PE20150957A1 - Celulas para producir iduronato-2-sulfatasa recombinante - Google Patents

Celulas para producir iduronato-2-sulfatasa recombinante

Info

Publication number
PE20150957A1
PE20150957A1 PE2014002538A PE2014002538A PE20150957A1 PE 20150957 A1 PE20150957 A1 PE 20150957A1 PE 2014002538 A PE2014002538 A PE 2014002538A PE 2014002538 A PE2014002538 A PE 2014002538A PE 20150957 A1 PE20150957 A1 PE 20150957A1
Authority
PE
Peru
Prior art keywords
cells
sulfatase
produce recombinant
fge
recombinant iduronate
Prior art date
Application number
PE2014002538A
Other languages
English (en)
Spanish (es)
Inventor
Ferenc Boldog
Michael Heartlein
Original Assignee
Shire Human Genetic Therapies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetic Therapies filed Critical Shire Human Genetic Therapies
Publication of PE20150957A1 publication Critical patent/PE20150957A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0051Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y108/00Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/99Oxidoreductases acting on sulfur groups as donors (1.8) with other acceptors (1.8.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/06Sulfuric ester hydrolases (3.1.6)
    • C12Y301/06013Iduronate-2-sulfatase (3.1.6.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/106Plasmid DNA for vertebrates
    • C12N2800/107Plasmid DNA for vertebrates for mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PE2014002538A 2012-06-29 2013-06-28 Celulas para producir iduronato-2-sulfatasa recombinante PE20150957A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261666719P 2012-06-29 2012-06-29

Publications (1)

Publication Number Publication Date
PE20150957A1 true PE20150957A1 (es) 2015-07-15

Family

ID=49778522

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2014002538A PE20150957A1 (es) 2012-06-29 2013-06-28 Celulas para producir iduronato-2-sulfatasa recombinante

Country Status (27)

Country Link
US (3) US9150841B2 (enExample)
EP (1) EP2874649B1 (enExample)
JP (3) JP6067849B2 (enExample)
KR (1) KR101710487B1 (enExample)
CN (2) CN107267460A (enExample)
AU (3) AU2013282400B2 (enExample)
BR (1) BR112014032560B1 (enExample)
CA (1) CA2877521C (enExample)
CL (1) CL2014003568A1 (enExample)
CO (1) CO7240394A2 (enExample)
CR (1) CR20140586A (enExample)
DO (1) DOP2014000298A (enExample)
EA (2) EA202090805A1 (enExample)
ES (1) ES2718346T3 (enExample)
GT (1) GT201400302A (enExample)
HK (1) HK1209331A1 (enExample)
IL (3) IL236343A (enExample)
MX (2) MX336716B (enExample)
MY (2) MY157086A (enExample)
NZ (2) NZ703137A (enExample)
PE (1) PE20150957A1 (enExample)
PH (2) PH12016500011B1 (enExample)
SG (2) SG10201509397SA (enExample)
TR (1) TR201904435T4 (enExample)
UA (1) UA118955C2 (enExample)
WO (1) WO2014005019A2 (enExample)
ZA (1) ZA201409396B (enExample)

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Also Published As

Publication number Publication date
MX366155B (es) 2019-06-28
US20160053238A1 (en) 2016-02-25
AU2018200710B2 (en) 2019-11-14
IL274266A (en) 2020-06-30
HK1209331A1 (en) 2016-04-01
JP2015521848A (ja) 2015-08-03
MY189314A (en) 2022-02-04
JP2016105737A (ja) 2016-06-16
BR112014032560A2 (pt) 2018-03-06
IL254560A0 (en) 2017-11-30
CO7240394A2 (es) 2015-04-17
EP2874649A4 (en) 2016-05-04
CA2877521A1 (en) 2014-01-03
WO2014005019A3 (en) 2014-02-27
JP6302499B2 (ja) 2018-03-28
KR101710487B1 (ko) 2017-02-27
TR201904435T4 (tr) 2019-05-21
GT201400302A (es) 2019-05-22
PH12014502868A1 (en) 2015-02-23
IL236343A0 (en) 2015-02-26
UA118955C2 (uk) 2019-04-10
CR20140586A (es) 2015-04-06
ES2718346T3 (es) 2019-07-01
NZ703137A (en) 2017-08-25
EP2874649A2 (en) 2015-05-27
DOP2014000298A (es) 2015-03-31
US20140004593A1 (en) 2014-01-02
CA2877521C (en) 2021-06-01
AU2018200710A1 (en) 2018-02-22
US20180010108A1 (en) 2018-01-11
JP6067849B2 (ja) 2017-01-25
CN104540517A (zh) 2015-04-22
AU2013282400B2 (en) 2016-02-04
JP6755272B2 (ja) 2020-09-16
IL274266B (en) 2021-04-29
PH12014502868B1 (en) 2015-02-23
US9719074B2 (en) 2017-08-01
WO2014005019A2 (en) 2014-01-03
IL236343A (en) 2017-10-31
SG10201509397SA (en) 2015-12-30
HK1209651A1 (en) 2016-04-08
AU2013282400A1 (en) 2015-01-29
US9150841B2 (en) 2015-10-06
EA202090805A1 (ru) 2020-11-30
MX336716B (es) 2016-01-28
MX2015000189A (es) 2015-04-08
EP2874649B1 (en) 2019-01-02
PH12016500011A1 (en) 2019-08-14
AU2016200460A1 (en) 2016-02-18
KR20150030242A (ko) 2015-03-19
BR112014032560B1 (pt) 2022-04-26
MY157086A (en) 2016-04-19
SG11201408702VA (en) 2015-02-27
JP2018088933A (ja) 2018-06-14
AU2016200460B2 (en) 2017-11-02
CN107267460A (zh) 2017-10-20
ZA201409396B (en) 2018-05-30
NZ734670A (en) 2019-12-20
EA035511B1 (ru) 2020-06-26
CL2014003568A1 (es) 2015-04-24
PH12016500011B1 (en) 2022-07-15
IL254560B (en) 2020-05-31
EA201492183A1 (ru) 2015-06-30

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