DK2485761T3 - Fremgangsmåder og sammensætninger til øgning af iduronat-2-sulfatase-aktivitet i CNS - Google Patents
Fremgangsmåder og sammensætninger til øgning af iduronat-2-sulfatase-aktivitet i CNS Download PDFInfo
- Publication number
- DK2485761T3 DK2485761T3 DK10822810.7T DK10822810T DK2485761T3 DK 2485761 T3 DK2485761 T3 DK 2485761T3 DK 10822810 T DK10822810 T DK 10822810T DK 2485761 T3 DK2485761 T3 DK 2485761T3
- Authority
- DK
- Denmark
- Prior art keywords
- iduronate
- cns
- compositions
- increasing
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/06—Sulfuric ester hydrolases (3.1.6)
- C12Y301/06013—Iduronate-2-sulfatase (3.1.6.13)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25037809P | 2009-10-09 | 2009-10-09 | |
US25604909P | 2009-10-29 | 2009-10-29 | |
PCT/US2010/052113 WO2011044542A1 (en) | 2009-10-09 | 2010-10-08 | Methods and compositions for increasing iduronate 2-sulfatase activity in the cns |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2485761T3 true DK2485761T3 (da) | 2019-05-06 |
Family
ID=43857180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10822810.7T DK2485761T3 (da) | 2009-10-09 | 2010-10-08 | Fremgangsmåder og sammensætninger til øgning af iduronat-2-sulfatase-aktivitet i CNS |
Country Status (11)
Country | Link |
---|---|
US (4) | US8834874B2 (da) |
EP (3) | EP2485761B1 (da) |
JP (5) | JP2013507131A (da) |
DK (1) | DK2485761T3 (da) |
ES (1) | ES2725200T3 (da) |
HR (1) | HRP20190690T1 (da) |
HU (1) | HUE044865T2 (da) |
PL (1) | PL2485761T3 (da) |
PT (1) | PT2485761T (da) |
SI (1) | SI2485761T1 (da) |
WO (1) | WO2011044542A1 (da) |
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- 2010-10-08 JP JP2012533375A patent/JP2013507131A/ja not_active Withdrawn
- 2010-10-08 ES ES10822810T patent/ES2725200T3/es active Active
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Publication number | Publication date |
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JP2023033321A (ja) | 2023-03-10 |
US8834874B2 (en) | 2014-09-16 |
PL2485761T3 (pl) | 2019-10-31 |
WO2011044542A1 (en) | 2011-04-14 |
EP3533467B1 (en) | 2023-07-26 |
HUE044865T2 (hu) | 2019-11-28 |
US20180251535A1 (en) | 2018-09-06 |
PT2485761T (pt) | 2019-05-30 |
EP2485761A4 (en) | 2013-04-03 |
US20190185551A2 (en) | 2019-06-20 |
US11028156B2 (en) | 2021-06-08 |
JP2021008488A (ja) | 2021-01-28 |
US20110110935A1 (en) | 2011-05-12 |
EP4273164A3 (en) | 2024-01-24 |
JP2016155805A (ja) | 2016-09-01 |
EP4273164A2 (en) | 2023-11-08 |
ES2725200T3 (es) | 2019-09-20 |
JP2013507131A (ja) | 2013-03-04 |
EP2485761A1 (en) | 2012-08-15 |
US20150004160A1 (en) | 2015-01-01 |
EP2485761B1 (en) | 2019-02-27 |
US20210253681A1 (en) | 2021-08-19 |
JP2018154629A (ja) | 2018-10-04 |
US10011651B2 (en) | 2018-07-03 |
HRP20190690T1 (hr) | 2019-06-28 |
EP3533467A3 (en) | 2020-01-15 |
EP3533467A2 (en) | 2019-09-04 |
SI2485761T1 (sl) | 2019-05-31 |
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