PE20142312A1 - Combinaciones terapeuticas y metodos para tratar el melanoma - Google Patents

Combinaciones terapeuticas y metodos para tratar el melanoma

Info

Publication number
PE20142312A1
PE20142312A1 PE2014000603A PE2014000603A PE20142312A1 PE 20142312 A1 PE20142312 A1 PE 20142312A1 PE 2014000603 A PE2014000603 A PE 2014000603A PE 2014000603 A PE2014000603 A PE 2014000603A PE 20142312 A1 PE20142312 A1 PE 20142312A1
Authority
PE
Peru
Prior art keywords
inhibitor
methods
cytotoxin
combination
etbr
Prior art date
Application number
PE2014000603A
Other languages
English (en)
Spanish (es)
Inventor
Paul Polakis
Jyoti Asundi
Suzanna Clark
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PE20142312A1 publication Critical patent/PE20142312A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PE2014000603A 2011-10-28 2012-10-24 Combinaciones terapeuticas y metodos para tratar el melanoma PE20142312A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161552893P 2011-10-28 2011-10-28
US201261678978P 2012-08-02 2012-08-02

Publications (1)

Publication Number Publication Date
PE20142312A1 true PE20142312A1 (es) 2015-01-25

Family

ID=48168400

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2014000603A PE20142312A1 (es) 2011-10-28 2012-10-24 Combinaciones terapeuticas y metodos para tratar el melanoma

Country Status (19)

Country Link
EP (1) EP2776051A4 (enrdf_load_stackoverflow)
JP (2) JP6251682B2 (enrdf_load_stackoverflow)
KR (1) KR20140097205A (enrdf_load_stackoverflow)
CN (1) CN104039340B (enrdf_load_stackoverflow)
AR (1) AR088509A1 (enrdf_load_stackoverflow)
AU (1) AU2012328980A1 (enrdf_load_stackoverflow)
BR (1) BR112014009953A2 (enrdf_load_stackoverflow)
CA (1) CA2850034A1 (enrdf_load_stackoverflow)
CL (1) CL2014001092A1 (enrdf_load_stackoverflow)
CO (1) CO7151543A2 (enrdf_load_stackoverflow)
EA (1) EA201490879A1 (enrdf_load_stackoverflow)
IL (1) IL232135A0 (enrdf_load_stackoverflow)
IN (1) IN2014CN03062A (enrdf_load_stackoverflow)
MX (1) MX2014004991A (enrdf_load_stackoverflow)
PE (1) PE20142312A1 (enrdf_load_stackoverflow)
PH (1) PH12014500925A1 (enrdf_load_stackoverflow)
SG (1) SG11201401815XA (enrdf_load_stackoverflow)
TW (1) TW201325613A (enrdf_load_stackoverflow)
WO (1) WO2013063001A1 (enrdf_load_stackoverflow)

Families Citing this family (10)

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PH12014500270A1 (en) 2011-08-01 2014-03-31 Genentech Inc Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors
US9216170B2 (en) 2012-03-19 2015-12-22 Hoffmann-La Roche Inc. Combination therapy for proliferative disorders
SG10202007111TA (en) 2014-07-15 2020-09-29 Genentech Inc Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors
US10617670B2 (en) * 2014-10-10 2020-04-14 Pfizer Inc. Synergistic auristatin combinations
AU2016302254B2 (en) * 2015-08-03 2019-09-12 Enb Therapeutics, Inc. Compositions and methods for treating cancers associated with ETBR activation
FR3053042B1 (fr) * 2016-06-24 2018-08-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Anticorps dirige contre le sous-type b des recepteurs aux endothelines et ses utilisations
JP7300394B2 (ja) 2017-01-17 2023-06-29 ヘパリジェニックス ゲーエムベーハー 肝再生の促進又は肝細胞死の低減もしくは予防のためのプロテインキナーゼ阻害
WO2024209089A1 (en) 2023-04-07 2024-10-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Use of antibody against the endothelin receptor b for diagnostic and therapeutic applications
FR3155708A1 (fr) * 2023-11-27 2025-05-30 Skymab Biotherapeutics Conjugue anticorps-medicament et ses utilisations
FR3155709A1 (fr) * 2023-11-27 2025-05-30 Skymab Biotherapeutics Conjugue anticorps-medicament et ses utilisations

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EP2776051A1 (en) 2014-09-17
BR112014009953A2 (pt) 2017-12-05
AR088509A1 (es) 2014-06-11
IN2014CN03062A (enrdf_load_stackoverflow) 2015-07-31
CN104039340A (zh) 2014-09-10
JP2018027948A (ja) 2018-02-22
WO2013063001A1 (en) 2013-05-02
MX2014004991A (es) 2014-05-22
EA201490879A1 (ru) 2014-08-29
CN104039340B (zh) 2017-04-05
TW201325613A (zh) 2013-07-01
JP6251682B2 (ja) 2017-12-20
CL2014001092A1 (es) 2014-07-25
SG11201401815XA (en) 2014-05-29
KR20140097205A (ko) 2014-08-06
IL232135A0 (en) 2014-05-28
AU2012328980A1 (en) 2014-04-24
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CO7151543A2 (es) 2014-12-29
CA2850034A1 (en) 2013-05-02

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