KR20140097205A - 흑색종을 치료하는 치료 조합물 및 방법 - Google Patents
흑색종을 치료하는 치료 조합물 및 방법 Download PDFInfo
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- KR20140097205A KR20140097205A KR1020147013878A KR20147013878A KR20140097205A KR 20140097205 A KR20140097205 A KR 20140097205A KR 1020147013878 A KR1020147013878 A KR 1020147013878A KR 20147013878 A KR20147013878 A KR 20147013878A KR 20140097205 A KR20140097205 A KR 20140097205A
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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| US61/678,978 | 2012-08-02 | ||
| PCT/US2012/061533 WO2013063001A1 (en) | 2011-10-28 | 2012-10-24 | Therapeutic combinations and methods of treating melanoma |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20170058432A (ko) * | 2014-10-10 | 2017-05-26 | 화이자 인코포레이티드 | 상승 효과적 아우리스타틴 조합 |
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| JP6238459B2 (ja) | 2011-08-01 | 2017-11-29 | ジェネンテック， インコーポレイテッド | Ｐｄ−１軸結合アンタゴニストとｍｅｋ阻害剤を使用する癌の治療方法 |
| US9216170B2 (en) | 2012-03-19 | 2015-12-22 | Hoffmann-La Roche Inc. | Combination therapy for proliferative disorders |
| CN106573060A (zh) | 2014-07-15 | 2017-04-19 | 豪夫迈·罗氏有限公司 | 使用pd‑1轴结合拮抗剂和mek抑制剂治疗癌症的组合物 |
| WO2017024032A2 (en) * | 2015-08-03 | 2017-02-09 | Enb Therapeutics, Llc | Compositions and methods for treating cancers associated with etbr activation |
| FR3053042B1 (fr) | 2016-06-24 | 2018-08-10 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Anticorps dirige contre le sous-type b des recepteurs aux endothelines et ses utilisations |
| AU2018209164B2 (en) | 2017-01-17 | 2021-11-04 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| WO2024209089A1 (en) | 2023-04-07 | 2024-10-10 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Use of antibody against the endothelin receptor b for diagnostic and therapeutic applications |
| FR3155708A1 (fr) * | 2023-11-27 | 2025-05-30 | Skymab Biotherapeutics | Conjugue anticorps-medicament et ses utilisations |
| FR3155709A1 (fr) * | 2023-11-27 | 2025-05-30 | Skymab Biotherapeutics | Conjugue anticorps-medicament et ses utilisations |
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2012
- 2012-10-24 EP EP12842985.9A patent/EP2776051A4/en not_active Withdrawn
- 2012-10-24 CN CN201280065175.XA patent/CN104039340B/zh not_active Expired - Fee Related
- 2012-10-24 AR ARP120103974A patent/AR088509A1/es unknown
- 2012-10-24 BR BR112014009953A patent/BR112014009953A2/pt not_active IP Right Cessation
- 2012-10-24 SG SG11201401815XA patent/SG11201401815XA/en unknown
- 2012-10-24 AU AU2012328980A patent/AU2012328980A1/en not_active Abandoned
- 2012-10-24 IN IN3062CHN2014 patent/IN2014CN03062A/en unknown
- 2012-10-24 KR KR1020147013878A patent/KR20140097205A/ko not_active Withdrawn
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- 2012-10-24 PH PH1/2014/500925A patent/PH12014500925A1/en unknown
- 2012-10-24 WO PCT/US2012/061533 patent/WO2013063001A1/en active Application Filing
- 2012-10-24 JP JP2014538892A patent/JP6251682B2/ja not_active Expired - Fee Related
- 2012-10-24 CA CA2850034A patent/CA2850034A1/en not_active Abandoned
- 2012-10-24 TW TW101139342A patent/TW201325613A/zh unknown
- 2012-10-24 PE PE2014000603A patent/PE20142312A1/es not_active Application Discontinuation
- 2012-10-24 EA EA201490879A patent/EA201490879A1/ru unknown
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2014
- 2014-04-16 CO CO14083118A patent/CO7151543A2/es not_active Application Discontinuation
- 2014-04-22 IL IL232135A patent/IL232135A0/en unknown
- 2014-04-28 CL CL2014001092A patent/CL2014001092A1/es unknown
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2017
- 2017-08-24 JP JP2017161010A patent/JP2018027948A/ja not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170058432A (ko) * | 2014-10-10 | 2017-05-26 | 화이자 인코포레이티드 | 상승 효과적 아우리스타틴 조합 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2776051A1 (en) | 2014-09-17 |
| PE20142312A1 (es) | 2015-01-25 |
| CN104039340A (zh) | 2014-09-10 |
| IN2014CN03062A (enrdf_load_stackoverflow) | 2015-07-31 |
| SG11201401815XA (en) | 2014-05-29 |
| CN104039340B (zh) | 2017-04-05 |
| EA201490879A1 (ru) | 2014-08-29 |
| IL232135A0 (en) | 2014-05-28 |
| CL2014001092A1 (es) | 2014-07-25 |
| BR112014009953A2 (pt) | 2017-12-05 |
| MX2014004991A (es) | 2014-05-22 |
| JP2018027948A (ja) | 2018-02-22 |
| TW201325613A (zh) | 2013-07-01 |
| JP2014532648A (ja) | 2014-12-08 |
| EP2776051A4 (en) | 2015-06-17 |
| JP6251682B2 (ja) | 2017-12-20 |
| AR088509A1 (es) | 2014-06-11 |
| WO2013063001A1 (en) | 2013-05-02 |
| AU2012328980A1 (en) | 2014-04-24 |
| CA2850034A1 (en) | 2013-05-02 |
| CO7151543A2 (es) | 2014-12-29 |
| PH12014500925A1 (en) | 2014-06-09 |
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