CO7151543A2 - Combinaciones terapéuticas y métodos para tratar el melanoma - Google Patents

Combinaciones terapéuticas y métodos para tratar el melanoma

Info

Publication number
CO7151543A2
CO7151543A2 CO14083118A CO14083118A CO7151543A2 CO 7151543 A2 CO7151543 A2 CO 7151543A2 CO 14083118 A CO14083118 A CO 14083118A CO 14083118 A CO14083118 A CO 14083118A CO 7151543 A2 CO7151543 A2 CO 7151543A2
Authority
CO
Colombia
Prior art keywords
methods
therapeutic combinations
treat melanoma
melanoma
treat
Prior art date
Application number
CO14083118A
Other languages
English (en)
Inventor
Paul Polakis
Jyoti Asundi
Suzanna Clark
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CO7151543A2 publication Critical patent/CO7151543A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Abstract

La invención proporciona combinaciones terapéuticas de anticuerpos anti-ETBR e inhibidores de la AMP quinasa y métodos para utilizarlos en el tratamiento del melanoma.
CO14083118A 2011-10-28 2014-04-16 Combinaciones terapéuticas y métodos para tratar el melanoma CO7151543A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161552893P 2011-10-28 2011-10-28
US201261678978P 2012-08-02 2012-08-02

Publications (1)

Publication Number Publication Date
CO7151543A2 true CO7151543A2 (es) 2014-12-29

Family

ID=48168400

Family Applications (1)

Application Number Title Priority Date Filing Date
CO14083118A CO7151543A2 (es) 2011-10-28 2014-04-16 Combinaciones terapéuticas y métodos para tratar el melanoma

Country Status (18)

Country Link
EP (1) EP2776051A4 (es)
JP (2) JP6251682B2 (es)
KR (1) KR20140097205A (es)
CN (1) CN104039340B (es)
AR (1) AR088509A1 (es)
AU (1) AU2012328980A1 (es)
BR (1) BR112014009953A2 (es)
CA (1) CA2850034A1 (es)
CL (1) CL2014001092A1 (es)
CO (1) CO7151543A2 (es)
EA (1) EA201490879A1 (es)
IL (1) IL232135A0 (es)
IN (1) IN2014CN03062A (es)
MX (1) MX2014004991A (es)
PE (1) PE20142312A1 (es)
SG (1) SG11201401815XA (es)
TW (1) TW201325613A (es)
WO (1) WO2013063001A1 (es)

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CN103842030B (zh) 2011-08-01 2018-07-31 霍夫曼-拉罗奇有限公司 使用pd-1轴结合拮抗剂和mek抑制剂治疗癌症的方法
US9216170B2 (en) 2012-03-19 2015-12-22 Hoffmann-La Roche Inc. Combination therapy for proliferative disorders
SG11201700074YA (en) 2014-07-15 2017-02-27 Genentech Inc Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors
RU2717570C2 (ru) 2014-10-10 2020-03-24 Пфайзер Инк. Синергистические комбинации ауристана
CA2994544C (en) * 2015-08-03 2021-03-30 Enb Therapeutics, Llc Compositions and methods for treating cancers associated with etbr activation
FR3053042B1 (fr) 2016-06-24 2018-08-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Anticorps dirige contre le sous-type b des recepteurs aux endothelines et ses utilisations
CA3049926A1 (en) 2017-01-17 2018-07-26 Heparegenix Gmbh Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death

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CN104039340B (zh) 2017-04-05
TW201325613A (zh) 2013-07-01
IN2014CN03062A (es) 2015-07-31
WO2013063001A1 (en) 2013-05-02
AR088509A1 (es) 2014-06-11
EA201490879A1 (ru) 2014-08-29
AU2012328980A1 (en) 2014-04-24
JP2018027948A (ja) 2018-02-22
EP2776051A1 (en) 2014-09-17
EP2776051A4 (en) 2015-06-17
JP6251682B2 (ja) 2017-12-20
CL2014001092A1 (es) 2014-07-25
IL232135A0 (en) 2014-05-28
SG11201401815XA (en) 2014-05-29
PE20142312A1 (es) 2015-01-25
CN104039340A (zh) 2014-09-10
BR112014009953A2 (pt) 2017-12-05
MX2014004991A (es) 2014-05-22
JP2014532648A (ja) 2014-12-08
CA2850034A1 (en) 2013-05-02
KR20140097205A (ko) 2014-08-06

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