PE20120817A1 - Peptidos tau antigenicos y usos de los mismos - Google Patents
Peptidos tau antigenicos y usos de los mismosInfo
- Publication number
- PE20120817A1 PE20120817A1 PE2012000116A PE2012000116A PE20120817A1 PE 20120817 A1 PE20120817 A1 PE 20120817A1 PE 2012000116 A PE2012000116 A PE 2012000116A PE 2012000116 A PE2012000116 A PE 2012000116A PE 20120817 A1 PE20120817 A1 PE 20120817A1
- Authority
- PE
- Peru
- Prior art keywords
- sequence
- seq
- amino acids
- vlp
- immunogen
- Prior art date
Links
- 230000000890 antigenic effect Effects 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 5
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 101000854943 Enterobacteria phage T4 Valyl-tRNA ligase modifier Proteins 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22986009P | 2009-07-30 | 2009-07-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20120817A1 true PE20120817A1 (es) | 2012-07-07 |
Family
ID=42941871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2012000116A PE20120817A1 (es) | 2009-07-30 | 2010-07-20 | Peptidos tau antigenicos y usos de los mismos |
Country Status (17)
Country | Link |
---|---|
US (1) | US20110177109A1 (enEXAMPLES) |
EP (1) | EP2459214A1 (enEXAMPLES) |
JP (1) | JP2013500326A (enEXAMPLES) |
KR (2) | KR20120049900A (enEXAMPLES) |
CN (1) | CN102596236B (enEXAMPLES) |
AR (1) | AR078085A1 (enEXAMPLES) |
AU (1) | AU2010277254B2 (enEXAMPLES) |
CA (1) | CA2768346A1 (enEXAMPLES) |
CO (1) | CO6612199A2 (enEXAMPLES) |
IN (1) | IN2012DN00446A (enEXAMPLES) |
MX (1) | MX2012001194A (enEXAMPLES) |
NZ (2) | NZ598356A (enEXAMPLES) |
PE (1) | PE20120817A1 (enEXAMPLES) |
RU (2) | RU2518291C2 (enEXAMPLES) |
SG (1) | SG177637A1 (enEXAMPLES) |
TW (2) | TW201436804A (enEXAMPLES) |
WO (1) | WO2011013034A1 (enEXAMPLES) |
Families Citing this family (45)
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MY160201A (en) | 2008-12-09 | 2017-02-28 | Coley Pharm Group Inc | Immunostimulatory oligonucleotides |
US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
EA032675B1 (ru) * | 2009-06-10 | 2019-07-31 | Нью-Йорк Юниверсити | Способ и композиции для лечения болезни альцгеймера и других таупатий |
AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
US9304138B2 (en) * | 2010-10-07 | 2016-04-05 | Katholieke Universiteit Leuven | Pharmaceutical composition |
US8703137B2 (en) | 2011-01-31 | 2014-04-22 | Intellect Neurosciences Inc. | Treatment of tauopathies |
MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
AR092779A1 (es) | 2011-10-07 | 2015-05-06 | Ac Immune Sa | Composicon farmaceutica que comprende anticuerpos que se unen a conformeros de proteinas tau |
EP2834270B1 (en) | 2012-04-05 | 2019-10-30 | AC Immune S.A. | Humanized tau antibody |
NZ703423A (en) * | 2012-07-03 | 2018-02-23 | Univ Washington | Antibodies to tau |
EP2885010B1 (en) | 2012-08-16 | 2020-01-01 | Ipierian, Inc. | Methods of treating a tauopathy |
US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
WO2014150877A2 (en) | 2013-03-15 | 2014-09-25 | Ac Immune S.A. | Anti-tau antibodies and methods of use |
US10195257B2 (en) * | 2013-07-28 | 2019-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response |
JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン,インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
WO2016007414A1 (en) | 2014-07-08 | 2016-01-14 | New York University | Tau imaging ligands and their uses in the diagnosis and treatment of tauopathy |
US20180050097A1 (en) * | 2015-03-25 | 2018-02-22 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
AU2016289753C1 (en) | 2015-07-06 | 2021-08-05 | UCB Biopharma SRL | Tau-binding antibodies |
JP6913078B2 (ja) | 2015-08-13 | 2021-08-04 | ニューヨーク・ユニバーシティ | タウの短縮型Asp421エピトープに特異的な、抗体を基にした分子、ならびにタウ異常症の診断および治療におけるそれらの使用 |
EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
AU2018355325B2 (en) | 2017-10-25 | 2024-11-28 | Ac Immune S.A. | Compositions of phosphorylated tau peptides and uses thereof |
CN119409835A (zh) * | 2017-10-27 | 2025-02-11 | 联脑科学公司 | Tau肽免疫原构建体 |
CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
CN110548135B (zh) * | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
WO2020073121A1 (en) * | 2018-10-07 | 2020-04-16 | The University Of British Columbia | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
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MX2021009508A (es) | 2019-02-08 | 2021-09-08 | Ac Immune Sa | Metodo para la administracion segura de una vacuna de peptido de tau fosforilado. |
US20200291391A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
US11155609B2 (en) | 2019-04-05 | 2021-10-26 | TauC3 Biologies Limited | Anti-TAUC3 antibodies and uses thereof |
US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
AU2020262899A1 (en) | 2019-04-24 | 2021-11-18 | Ac Immune S.A. | Heterologous administration of tau vaccines |
US12216122B2 (en) | 2019-05-20 | 2025-02-04 | Regeneron Pharmaceuticals, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (IDO1) |
CA3142040A1 (en) * | 2019-05-27 | 2020-12-03 | The University Of British Columbia | Conformation-specific epitopes in tau, antibodies thereto and methods related thereof |
GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
US20230302127A1 (en) * | 2020-08-07 | 2023-09-28 | Othair Prothena Limited | Tau vaccine for the treatment of alzheimer's disease |
WO2022054795A1 (ja) * | 2020-09-08 | 2022-03-17 | 国立大学法人大阪大学 | リン酸化タウタンパク質を標的とする免疫原性組成物 |
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CA2509484C (en) | 2002-12-10 | 2012-03-20 | Lorantis Ltd. | Stabilized immunogenic hbc chimer particles |
PL1701968T3 (pl) * | 2003-12-17 | 2015-11-30 | Wyeth Llc | Koniugaty nośników z peptydami immunogennymi i sposoby ich wytwarzania |
CA2572427A1 (en) | 2004-07-18 | 2006-01-18 | Heather L. Davis | Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses |
CA2574090A1 (en) | 2004-07-18 | 2006-12-21 | Coley Pharmaceutical Group, Ltd. | Methods and compositions for inducing innate immune responses |
RU2007117752A (ru) * | 2004-10-13 | 2008-11-20 | Аблинкс Н.В. (Be) | Нанотела (nanobodies тм) против бета-амилоида и полипептидов, содержащих бета-амилоид, для лечения нейродегенеративных заболеваний, таких как болезнь альцгеймера |
US8012936B2 (en) * | 2006-03-29 | 2011-09-06 | New York University | Tau fragments for immunotherapy |
ES2348312T3 (es) * | 2006-04-13 | 2010-12-02 | Bio Life Science Forschungs- Und Entwicklungsges.M.B.H. | Vacuna her-2/neu a base de múltiples péptidos. |
US20080166785A1 (en) | 2006-08-16 | 2008-07-10 | Monica Sala-Schaeffer | Polynucleotides allowing the expression and secretion of recombinant HBsAg virus-like particles containing a foreign peptide, their production and use |
EA032675B1 (ru) * | 2009-06-10 | 2019-07-31 | Нью-Йорк Юниверсити | Способ и композиции для лечения болезни альцгеймера и других таупатий |
FR3058624B1 (fr) | 2016-11-15 | 2018-12-07 | L'oreal | Brosse pour l'application d'un produit sur les cils et/ou les sourcils |
-
2010
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en active Application Filing
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
-
2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
-
2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW201106968A (en) | 2011-03-01 |
CO6612199A2 (es) | 2013-02-01 |
CN102596236A (zh) | 2012-07-18 |
SG177637A1 (en) | 2012-03-29 |
RU2014112002A (ru) | 2015-10-10 |
WO2011013034A1 (en) | 2011-02-03 |
NZ598356A (en) | 2014-06-27 |
AU2010277254B2 (en) | 2015-05-07 |
IN2012DN00446A (enEXAMPLES) | 2015-05-15 |
TWI461209B (zh) | 2014-11-21 |
EP2459214A1 (en) | 2012-06-06 |
JP2013500326A (ja) | 2013-01-07 |
US20110177109A1 (en) | 2011-07-21 |
RU2012102701A (ru) | 2013-09-10 |
AU2010277254A1 (en) | 2012-02-09 |
MX2012001194A (es) | 2012-03-07 |
KR20120049900A (ko) | 2012-05-17 |
WO2011013034A4 (en) | 2011-04-28 |
KR20130127547A (ko) | 2013-11-22 |
NZ618391A (en) | 2015-07-31 |
CN102596236B (zh) | 2015-06-24 |
TW201436804A (zh) | 2014-10-01 |
RU2518291C2 (ru) | 2014-06-10 |
CA2768346A1 (en) | 2011-02-03 |
AR078085A1 (es) | 2011-10-12 |
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