PE20120817A1 - Peptidos tau antigenicos y usos de los mismos - Google Patents
Peptidos tau antigenicos y usos de los mismosInfo
- Publication number
- PE20120817A1 PE20120817A1 PE2012000116A PE2012000116A PE20120817A1 PE 20120817 A1 PE20120817 A1 PE 20120817A1 PE 2012000116 A PE2012000116 A PE 2012000116A PE 2012000116 A PE2012000116 A PE 2012000116A PE 20120817 A1 PE20120817 A1 PE 20120817A1
- Authority
- PE
- Peru
- Prior art keywords
- sequence
- seq
- amino acids
- vlp
- immunogen
- Prior art date
Links
- 230000000890 antigenic effect Effects 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 5
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 101000854943 Enterobacteria phage T4 Valyl-tRNA ligase modifier Proteins 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22986009P | 2009-07-30 | 2009-07-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20120817A1 true PE20120817A1 (es) | 2012-07-07 |
Family
ID=42941871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2012000116A PE20120817A1 (es) | 2009-07-30 | 2010-07-20 | Peptidos tau antigenicos y usos de los mismos |
Country Status (17)
Country | Link |
---|---|
US (1) | US20110177109A1 (enEXAMPLES) |
EP (1) | EP2459214A1 (enEXAMPLES) |
JP (1) | JP2013500326A (enEXAMPLES) |
KR (2) | KR20130127547A (enEXAMPLES) |
CN (1) | CN102596236B (enEXAMPLES) |
AR (1) | AR078085A1 (enEXAMPLES) |
AU (1) | AU2010277254B2 (enEXAMPLES) |
CA (1) | CA2768346A1 (enEXAMPLES) |
CO (1) | CO6612199A2 (enEXAMPLES) |
IN (1) | IN2012DN00446A (enEXAMPLES) |
MX (1) | MX2012001194A (enEXAMPLES) |
NZ (2) | NZ618391A (enEXAMPLES) |
PE (1) | PE20120817A1 (enEXAMPLES) |
RU (2) | RU2518291C2 (enEXAMPLES) |
SG (1) | SG177637A1 (enEXAMPLES) |
TW (2) | TW201436804A (enEXAMPLES) |
WO (1) | WO2011013034A1 (enEXAMPLES) |
Families Citing this family (45)
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US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
CA2745096C (en) | 2008-12-09 | 2013-11-05 | Coley Pharmaceutical Group, Inc. | Immunostimulatory oligonucleotides |
UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
CA3239368A1 (en) | 2009-06-10 | 2010-12-16 | New York University | Immunological targeting of pathological tau proteins |
WO2012045882A2 (en) * | 2010-10-07 | 2012-04-12 | Ac Immune S.A. | Pharmaceutical composition |
AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
EP2670434B1 (en) | 2011-01-31 | 2018-12-26 | Tau Bio-Logic Corp. | Treatment of tauopathies |
MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
CN104080806B (zh) | 2011-10-07 | 2018-01-19 | Ac免疫有限公司 | 识别Tau的磷酸化特异抗体 |
CA2869438C (en) | 2012-04-05 | 2021-08-17 | Ac Immune S.A. | Humanized tau antibody |
NZ703423A (en) * | 2012-07-03 | 2018-02-23 | Univ Washington | Antibodies to tau |
NZ630542A (en) | 2012-08-16 | 2017-06-30 | Ipierian Inc | Methods of treating a tauopathy |
US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
JP6568514B2 (ja) | 2013-03-15 | 2019-08-28 | エーシー イミューン エス.エー. | 抗タウ抗体及び使用方法 |
EP3027205A4 (en) * | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
US10400018B2 (en) | 2014-02-14 | 2019-09-03 | Ipierian, Inc. | Tau peptides, anti-tau antibodies, and methods of use thereof |
TWI734975B (zh) | 2014-06-27 | 2021-08-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
CN107073297B (zh) | 2014-07-08 | 2021-09-14 | 纽约大学 | Tau显像配体和其在Tau蛋白病的诊断和治疗中的用途 |
WO2016154522A1 (en) * | 2015-03-25 | 2016-09-29 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
TN2017000543A1 (en) | 2015-07-06 | 2019-04-12 | Ucb Biopharma Sprl | Tau-binding antibodies |
JP6913078B2 (ja) | 2015-08-13 | 2021-08-04 | ニューヨーク・ユニバーシティ | タウの短縮型Asp421エピトープに特異的な、抗体を基にした分子、ならびにタウ異常症の診断および治療におけるそれらの使用 |
US11884707B2 (en) | 2016-09-29 | 2024-01-30 | Regeneron Pharmaceuticals, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase 1 (IDO1) and methods of making and using same |
GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
MA50465A (fr) | 2017-10-25 | 2020-09-02 | Ac Immune Sa | Compositions de peptides tau phosphorylés et leurs utilisations |
CN119409835A (zh) * | 2017-10-27 | 2025-02-11 | 联脑科学公司 | Tau肽免疫原构建体 |
CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
CN110548135B (zh) * | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
CA3148562A1 (en) | 2018-10-07 | 2020-04-16 | Neil R. Cashman | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
BR112021015501A2 (pt) * | 2019-02-08 | 2021-10-19 | Prothena Biosciences Limited | Anticorpos que reconhecem tau |
KR20210125048A (ko) | 2019-02-08 | 2021-10-15 | 에이씨 이뮨 에스.에이. | 인산화 타우 펩티드 백신의 안전한 투여 방법 |
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WO2020201828A1 (en) | 2019-04-05 | 2020-10-08 | Tauc3 Biologics Limited | Anti-tauc3 antibodies and uses thereof |
US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
JP7617852B2 (ja) | 2019-04-24 | 2025-01-20 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | タウワクチンの異種投与 |
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KR20220034733A (ko) * | 2019-05-27 | 2022-03-18 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 타우의 입체형태-특이적 에피토프, 이에 대한 항체 및 이와 관련된 방법 |
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EP4212172A4 (en) * | 2020-09-08 | 2024-10-16 | Osaka University | Immunogenic composition targeting phosphorylated tau protein |
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CN118613496A (zh) * | 2021-09-29 | 2024-09-06 | 杨森制药公司 | 安全施用Tau磷酸肽缀合物的方法 |
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GB0209878D0 (en) | 2002-04-30 | 2002-06-05 | Glaxosmithkline Biolog Sa | Vaccine |
EP1532167B1 (en) | 2002-07-17 | 2012-01-25 | Cytos Biotechnology AG | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
EP2338510A1 (en) * | 2002-07-19 | 2011-06-29 | Novartis Pharma AG | Vaccine compositions containing amyloid beta1-6 antigen arrays |
NZ540620A (en) | 2002-12-10 | 2009-03-31 | Lorantis Ltd | Stabilized immunogenic HBc chimer particles |
WO2005058940A2 (en) * | 2003-12-17 | 2005-06-30 | Wyeth | Immunogenic peptide carrier conjugates and methods of producing same |
JP2008506789A (ja) | 2004-07-18 | 2008-03-06 | シーエスエル、リミテッド | インターフェロン−ガンマ応答強化を誘発するための免疫刺激複合体及びオリゴヌクレオチド処方物 |
JP2008506683A (ja) | 2004-07-18 | 2008-03-06 | コーリー ファーマシューティカル グループ, リミテッド | 先天免疫応答を誘導するための方法および組成物 |
RU2007117752A (ru) * | 2004-10-13 | 2008-11-20 | Аблинкс Н.В. (Be) | Нанотела (nanobodies тм) против бета-амилоида и полипептидов, содержащих бета-амилоид, для лечения нейродегенеративных заболеваний, таких как болезнь альцгеймера |
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EP1844788B1 (en) * | 2006-04-13 | 2010-07-14 | Bio Life Science Forschungs- und Entwicklungsges.m.b.H. | HER-2/neu multi-peptide vaccine |
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FR3058624B1 (fr) | 2016-11-15 | 2018-12-07 | L'oreal | Brosse pour l'application d'un produit sur les cils et/ou les sourcils |
-
2010
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en active Application Filing
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
-
2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
-
2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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TW201106968A (en) | 2011-03-01 |
WO2011013034A1 (en) | 2011-02-03 |
RU2014112002A (ru) | 2015-10-10 |
NZ618391A (en) | 2015-07-31 |
TWI461209B (zh) | 2014-11-21 |
WO2011013034A4 (en) | 2011-04-28 |
CO6612199A2 (es) | 2013-02-01 |
TW201436804A (zh) | 2014-10-01 |
CA2768346A1 (en) | 2011-02-03 |
SG177637A1 (en) | 2012-03-29 |
RU2518291C2 (ru) | 2014-06-10 |
US20110177109A1 (en) | 2011-07-21 |
KR20130127547A (ko) | 2013-11-22 |
MX2012001194A (es) | 2012-03-07 |
EP2459214A1 (en) | 2012-06-06 |
AR078085A1 (es) | 2011-10-12 |
RU2012102701A (ru) | 2013-09-10 |
CN102596236B (zh) | 2015-06-24 |
CN102596236A (zh) | 2012-07-18 |
JP2013500326A (ja) | 2013-01-07 |
AU2010277254B2 (en) | 2015-05-07 |
NZ598356A (en) | 2014-06-27 |
KR20120049900A (ko) | 2012-05-17 |
IN2012DN00446A (enEXAMPLES) | 2015-05-15 |
AU2010277254A1 (en) | 2012-02-09 |
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