KR20120049900A - 항원성 타우 펩타이드 및 이의 용도 - Google Patents
항원성 타우 펩타이드 및 이의 용도 Download PDFInfo
- Publication number
- KR20120049900A KR20120049900A KR1020127005415A KR20127005415A KR20120049900A KR 20120049900 A KR20120049900 A KR 20120049900A KR 1020127005415 A KR1020127005415 A KR 1020127005415A KR 20127005415 A KR20127005415 A KR 20127005415A KR 20120049900 A KR20120049900 A KR 20120049900A
- Authority
- KR
- South Korea
- Prior art keywords
- peptide
- tau
- antigenic
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22986009P | 2009-07-30 | 2009-07-30 | |
| US61/229,860 | 2009-07-30 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137028550A Division KR20130127547A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20120049900A true KR20120049900A (ko) | 2012-05-17 |
Family
ID=42941871
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127005415A Abandoned KR20120049900A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
| KR1020137028550A Ceased KR20130127547A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137028550A Ceased KR20130127547A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20110177109A1 (enEXAMPLES) |
| EP (1) | EP2459214A1 (enEXAMPLES) |
| JP (1) | JP2013500326A (enEXAMPLES) |
| KR (2) | KR20120049900A (enEXAMPLES) |
| CN (1) | CN102596236B (enEXAMPLES) |
| AR (1) | AR078085A1 (enEXAMPLES) |
| AU (1) | AU2010277254B2 (enEXAMPLES) |
| CA (1) | CA2768346A1 (enEXAMPLES) |
| CO (1) | CO6612199A2 (enEXAMPLES) |
| IN (1) | IN2012DN00446A (enEXAMPLES) |
| MX (1) | MX2012001194A (enEXAMPLES) |
| NZ (2) | NZ618391A (enEXAMPLES) |
| PE (1) | PE20120817A1 (enEXAMPLES) |
| RU (2) | RU2518291C2 (enEXAMPLES) |
| SG (1) | SG177637A1 (enEXAMPLES) |
| TW (2) | TWI461209B (enEXAMPLES) |
| WO (1) | WO2011013034A1 (enEXAMPLES) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG171829A1 (en) | 2008-12-09 | 2011-07-28 | Coley Pharm Group Inc | Immunostimulatory oligonucleotides |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| CA3239368A1 (en) | 2009-06-10 | 2010-12-16 | New York University | Immunological targeting of pathological tau proteins |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| RU2603078C2 (ru) * | 2010-10-07 | 2016-11-20 | Ац Иммуне С.А. | Фармацевтическая композиция |
| US20120244174A1 (en) | 2011-01-31 | 2012-09-27 | Intellect Neurosciences Inc. | Treatment of tauopathies |
| MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| AR092779A1 (es) | 2011-10-07 | 2015-05-06 | Ac Immune Sa | Composicon farmaceutica que comprende anticuerpos que se unen a conformeros de proteinas tau |
| US9657091B2 (en) | 2012-04-05 | 2017-05-23 | Ac Immune S.A. | Humanized tau antibody |
| KR102494798B1 (ko) * | 2012-07-03 | 2023-02-06 | 워싱턴 유니버시티 | Tau에 대한 항체 |
| HUE048780T2 (hu) | 2012-08-16 | 2020-09-28 | Ipierian Inc | Tauopátia kezelésére szolgáló módszerek |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| US9598485B2 (en) | 2013-03-15 | 2017-03-21 | Ac Immune S.A. | Anti-tau antibodies and methods of use |
| US10195257B2 (en) * | 2013-07-28 | 2019-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response |
| US10400018B2 (en) | 2014-02-14 | 2019-09-03 | Ipierian, Inc. | Tau peptides, anti-tau antibodies, and methods of use thereof |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| EP3166688B1 (en) | 2014-07-08 | 2024-08-21 | New York University | Tau imaging ligands and their uses in the diagnosis and treatment of tauopathy |
| US20180050097A1 (en) * | 2015-03-25 | 2018-02-22 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
| MA42380A (fr) | 2015-07-06 | 2018-05-16 | Ucb Biopharma Sprl | Anticorps se liant à tau |
| EP3334453A4 (en) | 2015-08-13 | 2019-02-06 | New York University | ANTIBODY-BASED SPECIFIC MOLECULES AND THEIR USES IN THE DIAGNOSIS AND TREATMENT OF TAUOPATHY, FOR TAU'S SPECIFIC ASP421 EPITOP |
| EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
| GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
| EA202091012A1 (ru) | 2017-10-25 | 2020-08-27 | Янссен Фармасьютикалз, Инк. | Композиции фосфорилированных тау-пептидов и их применения |
| SG11202003624SA (en) * | 2017-10-27 | 2020-05-28 | United Neuroscience | Tau peptide immunogen constructs |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
| CN110548135B (zh) | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
| GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
| AU2019356804B2 (en) * | 2018-10-07 | 2025-05-29 | Promis Neurosciences, Inc. | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
| JP7681316B2 (ja) * | 2019-02-08 | 2025-05-22 | プロセナ バイオサイエンシーズ リミテッド | タウを認識する抗体 |
| KR20210125048A (ko) | 2019-02-08 | 2021-10-15 | 에이씨 이뮨 에스.에이. | 인산화 타우 펩티드 백신의 안전한 투여 방법 |
| US20200291391A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| US11155609B2 (en) | 2019-04-05 | 2021-10-26 | TauC3 Biologies Limited | Anti-TAUC3 antibodies and uses thereof |
| JP7617852B2 (ja) | 2019-04-24 | 2025-01-20 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | タウワクチンの異種投与 |
| WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
| KR20220034733A (ko) * | 2019-05-27 | 2022-03-18 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 타우의 입체형태-특이적 에피토프, 이에 대한 항체 및 이와 관련된 방법 |
| GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| JP2023536746A (ja) * | 2020-08-07 | 2023-08-29 | プロシーナ バイオサイエンシーズ リミテッド | アルツハイマー病の処置のためのタウワクチン |
| JP7687699B2 (ja) * | 2020-09-08 | 2025-06-03 | 国立大学法人大阪大学 | リン酸化タウタンパク質を標的とする免疫原性組成物 |
| IL311337A (en) * | 2021-09-08 | 2024-05-01 | Joint Stock Company «Biocad» | A bispecific antibody that includes a heterogeneous dimer based on MHC proteins |
| KR20240082368A (ko) * | 2021-09-29 | 2024-06-10 | 얀센 파마슈티칼즈, 인코포레이티드 | 타우 포스포펩티드 접합체의 안전한 투여 방법 |
| CN115894659B (zh) * | 2022-10-19 | 2023-11-10 | 上海优宁维生物科技股份有限公司 | 微管相关蛋白Tau抗原及其制备方法和应用 |
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2010
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en active Application Filing
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| NZ598356A (en) | 2014-06-27 |
| AR078085A1 (es) | 2011-10-12 |
| CA2768346A1 (en) | 2011-02-03 |
| SG177637A1 (en) | 2012-03-29 |
| KR20130127547A (ko) | 2013-11-22 |
| CO6612199A2 (es) | 2013-02-01 |
| PE20120817A1 (es) | 2012-07-07 |
| CN102596236A (zh) | 2012-07-18 |
| US20110177109A1 (en) | 2011-07-21 |
| AU2010277254B2 (en) | 2015-05-07 |
| RU2518291C2 (ru) | 2014-06-10 |
| WO2011013034A1 (en) | 2011-02-03 |
| WO2011013034A4 (en) | 2011-04-28 |
| TWI461209B (zh) | 2014-11-21 |
| NZ618391A (en) | 2015-07-31 |
| CN102596236B (zh) | 2015-06-24 |
| MX2012001194A (es) | 2012-03-07 |
| TW201436804A (zh) | 2014-10-01 |
| TW201106968A (en) | 2011-03-01 |
| RU2012102701A (ru) | 2013-09-10 |
| EP2459214A1 (en) | 2012-06-06 |
| AU2010277254A1 (en) | 2012-02-09 |
| JP2013500326A (ja) | 2013-01-07 |
| RU2014112002A (ru) | 2015-10-10 |
| IN2012DN00446A (enEXAMPLES) | 2015-05-15 |
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