PE20120689A1 - Derivados de 5-fluoro-2-oxopirimidina-1(2h)-carboxilato - Google Patents
Derivados de 5-fluoro-2-oxopirimidina-1(2h)-carboxilatoInfo
- Publication number
- PE20120689A1 PE20120689A1 PE2012000170A PE2012000170A PE20120689A1 PE 20120689 A1 PE20120689 A1 PE 20120689A1 PE 2012000170 A PE2012000170 A PE 2012000170A PE 2012000170 A PE2012000170 A PE 2012000170A PE 20120689 A1 PE20120689 A1 PE 20120689A1
- Authority
- PE
- Peru
- Prior art keywords
- fluoro
- oxopyrimidine
- optionally substituted
- carboxylate
- compounds
- Prior art date
Links
- HRHMGDXHJNYKSR-UHFFFAOYSA-N OC(=O)N1C=C(F)C=NC1=O Chemical class OC(=O)N1C=C(F)C=NC1=O HRHMGDXHJNYKSR-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 2,2-DIMETHYL-PROPYL Chemical class 0.000 abstract 1
- 101000977048 Streptomyces cinnamonensis Uncharacterized protein in mutB 3'region Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- MMNNNCCLKAWPPZ-UHFFFAOYSA-N ethyl 4-amino-5-fluoro-2-oxopyrimidine-1-carboxylate Chemical compound CCOC(=O)N1C=C(F)C(N)=NC1=O MMNNNCCLKAWPPZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- CJEOHCPDDTWSQV-UHFFFAOYSA-N o-phenyl 4-amino-5-fluoro-2-oxopyrimidine-1-carbothioate Chemical compound C1=C(F)C(N)=NC(=O)N1C(=S)OC1=CC=CC=C1 CJEOHCPDDTWSQV-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23223209P | 2009-08-07 | 2009-08-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20120689A1 true PE20120689A1 (es) | 2012-06-06 |
Family
ID=43535293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2012000170A PE20120689A1 (es) | 2009-08-07 | 2010-08-05 | Derivados de 5-fluoro-2-oxopirimidina-1(2h)-carboxilato |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8318758B2 (enExample) |
| EP (1) | EP2462133B1 (enExample) |
| JP (1) | JP5818791B2 (enExample) |
| KR (1) | KR101792286B1 (enExample) |
| CN (1) | CN102548979B (enExample) |
| AU (1) | AU2010279408B2 (enExample) |
| BR (1) | BR112012002807B1 (enExample) |
| CA (1) | CA2769251C (enExample) |
| CL (1) | CL2012000314A1 (enExample) |
| CO (1) | CO6491089A2 (enExample) |
| CR (1) | CR20120033A (enExample) |
| DK (1) | DK2462133T3 (enExample) |
| EA (1) | EA022930B1 (enExample) |
| EC (1) | ECSP12011651A (enExample) |
| ES (1) | ES2506169T3 (enExample) |
| HN (1) | HN2012000261A (enExample) |
| IL (1) | IL217954A (enExample) |
| IN (1) | IN2012DN00695A (enExample) |
| MX (1) | MX2012001623A (enExample) |
| NI (1) | NI201200019A (enExample) |
| NZ (1) | NZ597638A (enExample) |
| PE (1) | PE20120689A1 (enExample) |
| PL (1) | PL2462133T3 (enExample) |
| PT (1) | PT2462133E (enExample) |
| RS (1) | RS53658B1 (enExample) |
| UA (1) | UA106086C2 (enExample) |
| WO (1) | WO2011017544A1 (enExample) |
| ZA (1) | ZA201305992B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA022289B1 (ru) * | 2009-08-07 | 2015-12-30 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Производные n1-сульфонил-5-фторпиримидинона |
| CN104994859B (zh) * | 2012-12-28 | 2018-10-26 | 阿达玛马克西姆股份有限公司 | 1-(取代的苯甲酰基)-5-氟-4-亚氨基-3-甲基-3,4-二氢嘧啶-2(1h)-酮衍生物 |
| AU2013370490B2 (en) | 2012-12-28 | 2018-05-10 | Adama Makhteshim Ltd. | N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxamide derivatives |
| CN110003118A (zh) * | 2012-12-28 | 2019-07-12 | 阿达玛马克西姆股份有限公司 | 制备羧酸酯衍生物的方法 |
| KR102309245B1 (ko) | 2012-12-31 | 2021-10-06 | 아다마 마켓심 리미티드 | 살진균제로서의 3-알킬-5-플루오로-4-치환된-이미노-3,4-디히드로피리미딘-2(1h)-온 유도체 |
| JP6585057B2 (ja) | 2013-12-31 | 2019-10-02 | アダマ・マクテシム・リミテッド | ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法 |
| EA030056B1 (ru) | 2013-12-31 | 2018-06-29 | Адама Мактешим Лтд. | Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами |
| WO2016040193A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
| CA3004297A1 (en) | 2015-11-06 | 2017-05-11 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-c]pyridines and their anti-inflammatory uses thereof |
| ES2933109T3 (es) | 2016-06-01 | 2023-02-02 | Biosplice Therapeutics Inc | Proceso para preparar N-(5-(3-(7-(3-fluorofenil)-3h-imidazo[4,5-c]piridin-2-il)-1h-indazol-5-il)piridin-3-il)-3-metilbutanamida |
| EP3655396A1 (en) | 2017-07-17 | 2020-05-27 | Adama Makhteshim Ltd. | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one |
| IL282939B2 (en) | 2018-11-05 | 2024-10-01 | Adama Makhteshim Ltd | Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4- dihydropyrimidin-2-one, and methods of use thereof |
| BR112022005464A2 (pt) | 2019-09-23 | 2022-08-16 | Adama Makhteshim Ltd | Processo para a preparação de 5-(flúor-4-imino-3-metil)-1-tosil-3,4-diidropirimidina-(1h)-ona |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3368938A (en) * | 1966-01-13 | 1968-02-13 | Hoffmann La Roche | Controlling fungi with 5-fluorocytosine |
| DK0888359T3 (da) * | 1996-03-11 | 2002-08-12 | Syngenta Participations Ag | Pyrimidin-4-on-derivat som pesticid |
| AU2003274652A1 (en) * | 2002-10-23 | 2004-05-13 | Obetherapy Biotechnology | Compounds, compositions and methods for modulating fat metabolism |
| EP2679586B1 (en) * | 2007-04-27 | 2016-02-10 | Daiichi Sankyo Company, Limited | Nitrogen-containing six-membered aromatic ring derivatives and pharmaceutical products containing the same |
| KR20110042204A (ko) | 2008-08-01 | 2011-04-25 | 다우 아그로사이언시즈 엘엘씨 | 살진균제로서의 5-플루오로시토신의 용도 |
-
2010
- 2010-08-05 NZ NZ597638A patent/NZ597638A/en unknown
- 2010-08-05 WO PCT/US2010/044585 patent/WO2011017544A1/en not_active Ceased
- 2010-08-05 AU AU2010279408A patent/AU2010279408B2/en not_active Ceased
- 2010-08-05 EP EP10807174.7A patent/EP2462133B1/en active Active
- 2010-08-05 IN IN695DEN2012 patent/IN2012DN00695A/en unknown
- 2010-08-05 DK DK10807174.7T patent/DK2462133T3/en active
- 2010-08-05 PE PE2012000170A patent/PE20120689A1/es not_active Application Discontinuation
- 2010-08-05 KR KR1020127005932A patent/KR101792286B1/ko not_active Expired - Fee Related
- 2010-08-05 US US12/851,304 patent/US8318758B2/en active Active
- 2010-08-05 BR BR112012002807-3A patent/BR112012002807B1/pt active IP Right Grant
- 2010-08-05 ES ES10807174.7T patent/ES2506169T3/es active Active
- 2010-08-05 JP JP2012523954A patent/JP5818791B2/ja active Active
- 2010-08-05 RS RS20140630A patent/RS53658B1/sr unknown
- 2010-08-05 PL PL10807174T patent/PL2462133T3/pl unknown
- 2010-08-05 UA UAA201202680A patent/UA106086C2/uk unknown
- 2010-08-05 PT PT108071747T patent/PT2462133E/pt unknown
- 2010-08-05 EA EA201270255A patent/EA022930B1/ru not_active IP Right Cessation
- 2010-08-05 CA CA2769251A patent/CA2769251C/en not_active Expired - Fee Related
- 2010-08-05 CN CN201080045339.3A patent/CN102548979B/zh active Active
- 2010-08-05 MX MX2012001623A patent/MX2012001623A/es active IP Right Grant
-
2012
- 2012-01-18 CR CR20120033A patent/CR20120033A/es unknown
- 2012-01-27 CO CO12012413A patent/CO6491089A2/es active IP Right Grant
- 2012-02-02 HN HN2012000261A patent/HN2012000261A/es unknown
- 2012-02-03 NI NI201200019A patent/NI201200019A/es unknown
- 2012-02-05 IL IL217954A patent/IL217954A/en active IP Right Grant
- 2012-02-06 CL CL2012000314A patent/CL2012000314A1/es unknown
- 2012-02-07 EC ECSP12011651 patent/ECSP12011651A/es unknown
-
2013
- 2013-08-14 ZA ZA2013/05992A patent/ZA201305992B/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |