CN102548979B - 5-氟代-2-氧代嘧啶-1(2h)-甲酸酯衍生物 - Google Patents

5-氟代-2-氧代嘧啶-1(2h)-甲酸酯衍生物 Download PDF

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Publication number
CN102548979B
CN102548979B CN201080045339.3A CN201080045339A CN102548979B CN 102548979 B CN102548979 B CN 102548979B CN 201080045339 A CN201080045339 A CN 201080045339A CN 102548979 B CN102548979 B CN 102548979B
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China
Prior art keywords
insecticides
herbicides
compounds
phenyl
methyl
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CN201080045339.3A
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English (en)
Chinese (zh)
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CN102548979A (zh
Inventor
T.博贝尔
K.布赖恩
B.洛斯巴赫
T.马丁
W.欧文
M.波班兹
S.索恩伯格
J.韦布斯特
姚成林
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Adama Makhteshim Ltd
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Dow AgroSciences LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN201080045339.3A 2009-08-07 2010-08-05 5-氟代-2-氧代嘧啶-1(2h)-甲酸酯衍生物 Active CN102548979B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23223209P 2009-08-07 2009-08-07
US61/232,232 2009-08-07
PCT/US2010/044585 WO2011017544A1 (en) 2009-08-07 2010-08-05 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives

Publications (2)

Publication Number Publication Date
CN102548979A CN102548979A (zh) 2012-07-04
CN102548979B true CN102548979B (zh) 2015-05-13

Family

ID=43535293

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Application Number Title Priority Date Filing Date
CN201080045339.3A Active CN102548979B (zh) 2009-08-07 2010-08-05 5-氟代-2-氧代嘧啶-1(2h)-甲酸酯衍生物

Country Status (28)

Country Link
US (1) US8318758B2 (enExample)
EP (1) EP2462133B1 (enExample)
JP (1) JP5818791B2 (enExample)
KR (1) KR101792286B1 (enExample)
CN (1) CN102548979B (enExample)
AU (1) AU2010279408B2 (enExample)
BR (1) BR112012002807B1 (enExample)
CA (1) CA2769251C (enExample)
CL (1) CL2012000314A1 (enExample)
CO (1) CO6491089A2 (enExample)
CR (1) CR20120033A (enExample)
DK (1) DK2462133T3 (enExample)
EA (1) EA022930B1 (enExample)
EC (1) ECSP12011651A (enExample)
ES (1) ES2506169T3 (enExample)
HN (1) HN2012000261A (enExample)
IL (1) IL217954A (enExample)
IN (1) IN2012DN00695A (enExample)
MX (1) MX2012001623A (enExample)
NI (1) NI201200019A (enExample)
NZ (1) NZ597638A (enExample)
PE (1) PE20120689A1 (enExample)
PL (1) PL2462133T3 (enExample)
PT (1) PT2462133E (enExample)
RS (1) RS53658B1 (enExample)
UA (1) UA106086C2 (enExample)
WO (1) WO2011017544A1 (enExample)
ZA (1) ZA201305992B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA106764C2 (uk) * 2009-08-07 2014-10-10 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні n1-сульфоніл-5-фторпіримідинону
US9622474B2 (en) * 2012-12-28 2017-04-18 Adama Makhteshim Ltd. N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2H)-carboxylate derivatives
HK1214518A1 (zh) * 2012-12-28 2016-07-29 Adama Makhteshim Ltd. 1-(经取代之苯甲醯基)-5-氟-4-亚胺基-3-甲基-3，4-二氢嘧啶-2(1h)-酮衍生物
US9321734B2 (en) 2012-12-28 2016-04-26 Dow Agrosciences Llc N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2H)-carboxamide derivatives
AU2013370494B2 (en) 2012-12-31 2017-08-17 Adama Makhteshim Ltd. 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1H)-one derivatives as fungicides
CN106068268A (zh) 2013-12-31 2016-11-02 阿达玛马克西姆股份有限公司 5‑氟‑4‑亚氨基‑3‑（烷基/取代烷基）‑1‑（芳基磺酰基）‑3,4‑二氢嘧啶‑2（1h）‑酮及其制备方法
EA030056B1 (ru) 2013-12-31 2018-06-29 Адама Мактешим Лтд. Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2017079759A1 (en) 2015-11-06 2017-05-11 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-c]pyridines and their anti-inflammatory uses thereof
SG10201912248RA (en) 2016-06-01 2020-02-27 Samumed Llc Process for preparing n-(5-(3-(7-(3-fluorophenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide
MA49639A (fr) 2017-07-17 2020-05-27 Adama Makhteshim Ltd Polymorphes de 5-fluoro-4-imino-3-méthyl-1-tosyl-3,4-dihydropyrimidin-2-one
CR20210270A (es) 2018-11-05 2021-07-20 Adama Makhteshim Ltd Mezclas y composiciones que comprenden 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2-ona, y métodos de uso de los mismos
US12466796B2 (en) 2019-09-23 2025-11-11 Adama Makhteshim Ltd. Process for preparing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1H)-one and derivatives of the compound

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3368938A (en) * 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU716248B2 (en) * 1996-03-11 2000-02-24 Novartis Ag Pyrimidin-4-one derivatives as pesticide
AU2003274652A1 (en) * 2002-10-23 2004-05-13 Obetherapy Biotechnology Compounds, compositions and methods for modulating fat metabolism
CN101730691A (zh) * 2007-04-27 2010-06-09 阿斯比奥制药株式会社 含氮芳香族六元环衍生物及含有它们的药物
UA107651C2 (en) 2008-08-01 2015-02-10 Dow Agrosciences Llc Use of 5-fluorocytosine as a fungicide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3368938A (en) * 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine

Also Published As

Publication number Publication date
IL217954A0 (en) 2012-03-29
RS53658B1 (sr) 2015-04-30
CL2012000314A1 (es) 2012-10-05
US20110034491A1 (en) 2011-02-10
KR101792286B1 (ko) 2017-10-31
BR112012002807B1 (pt) 2018-07-10
PT2462133E (pt) 2014-12-26
CR20120033A (es) 2012-03-22
EA022930B1 (ru) 2016-03-31
EA201270255A1 (ru) 2012-07-30
KR20120043069A (ko) 2012-05-03
JP2013501726A (ja) 2013-01-17
AU2010279408B2 (en) 2015-09-10
BR112012002807A8 (pt) 2017-07-11
NZ597638A (en) 2014-06-27
ZA201305992B (en) 2014-10-29
CA2769251A1 (en) 2011-02-10
WO2011017544A1 (en) 2011-02-10
EP2462133A4 (en) 2013-01-16
US8318758B2 (en) 2012-11-27
CN102548979A (zh) 2012-07-04
UA106086C2 (uk) 2014-07-25
AU2010279408A1 (en) 2012-02-09
DK2462133T3 (en) 2015-01-05
JP5818791B2 (ja) 2015-11-18
MX2012001623A (es) 2012-04-11
ECSP12011651A (es) 2012-03-30
HK1172892A1 (en) 2013-05-03
EP2462133B1 (en) 2014-09-24
PE20120689A1 (es) 2012-06-06
IN2012DN00695A (enExample) 2015-06-19
IL217954A (en) 2016-02-29
HN2012000261A (es) 2015-01-05
EP2462133A1 (en) 2012-06-13
NI201200019A (es) 2012-05-22
CO6491089A2 (es) 2012-07-31
ES2506169T3 (es) 2014-10-13
BR112012002807A2 (pt) 2015-10-13
PL2462133T3 (pl) 2015-03-31
CA2769251C (en) 2018-05-15

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