JP5818791B2 - ５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体 - Google Patents

５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体 Download PDF

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JP5818791B2
JP5818791B2 JP2012523954A JP2012523954A JP5818791B2 JP 5818791 B2 JP5818791 B2 JP 5818791B2 JP 2012523954 A JP2012523954 A JP 2012523954A JP 2012523954 A JP2012523954 A JP 2012523954A JP 5818791 B2 JP5818791 B2 JP 5818791B2
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membered
optionally substituted
benzyl
phenyl
ring system
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Japanese (ja)
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JP2013501726A5 (enExample
JP2013501726A (ja
Inventor
ボベル，ティモシー
ブライアン，クリスティー
ロールスバッハ，ベス
マーティン，ティモシー
オーウェン，ダブリュー．
ポバンズ，マーク
ソーンバーグ，スコット
ウェブスター，ジェフェリー
ヤオ，チェンリン
Original Assignee
ダウ アグロサイエンシィズ エルエルシー
ダウ アグロサイエンシィズ エルエルシー
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Application filed by ダウ アグロサイエンシィズ エルエルシー, ダウ アグロサイエンシィズ エルエルシー filed Critical ダウ アグロサイエンシィズ エルエルシー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms

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  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2012523954A 2009-08-07 2010-08-05 ５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体 Active JP5818791B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23223209P 2009-08-07 2009-08-07
US61/232,232 2009-08-07
PCT/US2010/044585 WO2011017544A1 (en) 2009-08-07 2010-08-05 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives

Publications (3)

Publication Number Publication Date
JP2013501726A JP2013501726A (ja) 2013-01-17
JP2013501726A5 JP2013501726A5 (enExample) 2015-04-16
JP5818791B2 true JP5818791B2 (ja) 2015-11-18

Family

ID=43535293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012523954A Active JP5818791B2 (ja) 2009-08-07 2010-08-05 ５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体

Country Status (28)

Country Link
US (1) US8318758B2 (enExample)
EP (1) EP2462133B1 (enExample)
JP (1) JP5818791B2 (enExample)
KR (1) KR101792286B1 (enExample)
CN (1) CN102548979B (enExample)
AU (1) AU2010279408B2 (enExample)
BR (1) BR112012002807B1 (enExample)
CA (1) CA2769251C (enExample)
CL (1) CL2012000314A1 (enExample)
CO (1) CO6491089A2 (enExample)
CR (1) CR20120033A (enExample)
DK (1) DK2462133T3 (enExample)
EA (1) EA022930B1 (enExample)
EC (1) ECSP12011651A (enExample)
ES (1) ES2506169T3 (enExample)
HN (1) HN2012000261A (enExample)
IL (1) IL217954A (enExample)
IN (1) IN2012DN00695A (enExample)
MX (1) MX2012001623A (enExample)
NI (1) NI201200019A (enExample)
NZ (1) NZ597638A (enExample)
PE (1) PE20120689A1 (enExample)
PL (1) PL2462133T3 (enExample)
PT (1) PT2462133E (enExample)
RS (1) RS53658B1 (enExample)
UA (1) UA106086C2 (enExample)
WO (1) WO2011017544A1 (enExample)
ZA (1) ZA201305992B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA022289B1 (ru) * 2009-08-07 2015-12-30 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Производные n1-сульфонил-5-фторпиримидинона
CN104994859B (zh) * 2012-12-28 2018-10-26 阿达玛马克西姆股份有限公司 1-(取代的苯甲酰基)-5-氟-4-亚氨基-3-甲基-3,4-二氢嘧啶-2(1h)-酮衍生物
AU2013370490B2 (en) 2012-12-28 2018-05-10 Adama Makhteshim Ltd. N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxamide derivatives
CN110003118A (zh) * 2012-12-28 2019-07-12 阿达玛马克西姆股份有限公司 制备羧酸酯衍生物的方法
KR102309245B1 (ko) 2012-12-31 2021-10-06 아다마 마켓심 리미티드 살진균제로서의 3-알킬-5-플루오로-4-치환된-이미노-3,4-디히드로피리미딘-2(1h)-온 유도체
JP6585057B2 (ja) 2013-12-31 2019-10-02 アダマ・マクテシム・リミテッド ５−フルオロ−４−イミノ−３−（アルキル／置換アルキル）−１−（アリールスルホニル）−３，４−ジヒドロピリミジン−２（１ｈ）−オンおよびそれらの調製方法
EA030056B1 (ru) 2013-12-31 2018-06-29 Адама Мактешим Лтд. Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
CA3004297A1 (en) 2015-11-06 2017-05-11 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-c]pyridines and their anti-inflammatory uses thereof
ES2933109T3 (es) 2016-06-01 2023-02-02 Biosplice Therapeutics Inc Proceso para preparar N-(5-(3-(7-(3-fluorofenil)-3h-imidazo[4,5-c]piridin-2-il)-1h-indazol-5-il)piridin-3-il)-3-metilbutanamida
EP3655396A1 (en) 2017-07-17 2020-05-27 Adama Makhteshim Ltd. Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one
IL282939B2 (en) 2018-11-05 2024-10-01 Adama Makhteshim Ltd Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4- dihydropyrimidin-2-one, and methods of use thereof
BR112022005464A2 (pt) 2019-09-23 2022-08-16 Adama Makhteshim Ltd Processo para a preparação de 5-(flúor-4-imino-3-metil)-1-tosil-3,4-diidropirimidina-(1h)-ona

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3368938A (en) * 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine
DK0888359T3 (da) * 1996-03-11 2002-08-12 Syngenta Participations Ag Pyrimidin-4-on-derivat som pesticid
AU2003274652A1 (en) * 2002-10-23 2004-05-13 Obetherapy Biotechnology Compounds, compositions and methods for modulating fat metabolism
EP2679586B1 (en) * 2007-04-27 2016-02-10 Daiichi Sankyo Company, Limited Nitrogen-containing six-membered aromatic ring derivatives and pharmaceutical products containing the same
KR20110042204A (ko) 2008-08-01 2011-04-25 다우 아그로사이언시즈 엘엘씨 살진균제로서의 5-플루오로시토신의 용도

Also Published As

Publication number Publication date
CN102548979A (zh) 2012-07-04
RS53658B1 (sr) 2015-04-30
AU2010279408B2 (en) 2015-09-10
ES2506169T3 (es) 2014-10-13
NI201200019A (es) 2012-05-22
US20110034491A1 (en) 2011-02-10
ECSP12011651A (es) 2012-03-30
CA2769251C (en) 2018-05-15
BR112012002807A2 (pt) 2015-10-13
IL217954A (en) 2016-02-29
UA106086C2 (uk) 2014-07-25
KR20120043069A (ko) 2012-05-03
JP2013501726A (ja) 2013-01-17
BR112012002807B1 (pt) 2018-07-10
KR101792286B1 (ko) 2017-10-31
EP2462133B1 (en) 2014-09-24
PT2462133E (pt) 2014-12-26
US8318758B2 (en) 2012-11-27
MX2012001623A (es) 2012-04-11
ZA201305992B (en) 2014-10-29
EA201270255A1 (ru) 2012-07-30
NZ597638A (en) 2014-06-27
CO6491089A2 (es) 2012-07-31
BR112012002807A8 (pt) 2017-07-11
IN2012DN00695A (enExample) 2015-06-19
CL2012000314A1 (es) 2012-10-05
CN102548979B (zh) 2015-05-13
CR20120033A (es) 2012-03-22
EA022930B1 (ru) 2016-03-31
CA2769251A1 (en) 2011-02-10
PE20120689A1 (es) 2012-06-06
EP2462133A1 (en) 2012-06-13
HN2012000261A (es) 2015-01-05
DK2462133T3 (en) 2015-01-05
EP2462133A4 (en) 2013-01-16
WO2011017544A1 (en) 2011-02-10
HK1172892A1 (en) 2013-05-03
PL2462133T3 (pl) 2015-03-31
IL217954A0 (en) 2012-03-29
AU2010279408A1 (en) 2012-02-09

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