JP5818791B2 - ５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体 - Google Patents

５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体 Download PDF

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JP5818791B2
JP5818791B2 JP2012523954A JP2012523954A JP5818791B2 JP 5818791 B2 JP5818791 B2 JP 5818791B2 JP 2012523954 A JP2012523954 A JP 2012523954A JP 2012523954 A JP2012523954 A JP 2012523954A JP 5818791 B2 JP5818791 B2 JP 5818791B2
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membered
optionally substituted
benzyl
phenyl
ring system
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Japanese (ja)
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JP2013501726A (ja
JP2013501726A5 (enExample
Inventor
ボベル，ティモシー
ブライアン，クリスティー
ロールスバッハ，ベス
マーティン，ティモシー
オーウェン，ダブリュー．
ポバンズ，マーク
ソーンバーグ，スコット
ウェブスター，ジェフェリー
ヤオ，チェンリン
Original Assignee
ダウ アグロサイエンシィズ エルエルシー
ダウ アグロサイエンシィズ エルエルシー
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Application filed by ダウ アグロサイエンシィズ エルエルシー, ダウ アグロサイエンシィズ エルエルシー filed Critical ダウ アグロサイエンシィズ エルエルシー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2012523954A 2009-08-07 2010-08-05 ５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体 Active JP5818791B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23223209P 2009-08-07 2009-08-07
US61/232,232 2009-08-07
PCT/US2010/044585 WO2011017544A1 (en) 2009-08-07 2010-08-05 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives

Publications (3)

Publication Number Publication Date
JP2013501726A JP2013501726A (ja) 2013-01-17
JP2013501726A5 JP2013501726A5 (enExample) 2015-04-16
JP5818791B2 true JP5818791B2 (ja) 2015-11-18

Family

ID=43535293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012523954A Active JP5818791B2 (ja) 2009-08-07 2010-08-05 ５−フルオロ−２−オキソピリミジン−１（２ｈ）−カルボキシレート誘導体

Country Status (28)

Country Link
US (1) US8318758B2 (enExample)
EP (1) EP2462133B1 (enExample)
JP (1) JP5818791B2 (enExample)
KR (1) KR101792286B1 (enExample)
CN (1) CN102548979B (enExample)
AU (1) AU2010279408B2 (enExample)
BR (1) BR112012002807B1 (enExample)
CA (1) CA2769251C (enExample)
CL (1) CL2012000314A1 (enExample)
CO (1) CO6491089A2 (enExample)
CR (1) CR20120033A (enExample)
DK (1) DK2462133T3 (enExample)
EA (1) EA022930B1 (enExample)
EC (1) ECSP12011651A (enExample)
ES (1) ES2506169T3 (enExample)
HN (1) HN2012000261A (enExample)
IL (1) IL217954A (enExample)
IN (1) IN2012DN00695A (enExample)
MX (1) MX2012001623A (enExample)
NI (1) NI201200019A (enExample)
NZ (1) NZ597638A (enExample)
PE (1) PE20120689A1 (enExample)
PL (1) PL2462133T3 (enExample)
PT (1) PT2462133E (enExample)
RS (1) RS53658B1 (enExample)
UA (1) UA106086C2 (enExample)
WO (1) WO2011017544A1 (enExample)
ZA (1) ZA201305992B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5784603B2 (ja) * 2009-08-07 2015-09-24 ダウ アグロサイエンシィズ エルエルシー Ｎ１−スルホニル−５−フルオロピリミジノン誘導体
RU2015131149A (ru) 2012-12-28 2017-02-03 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи N-(замещенные)-5-фтор-4-имино-3-метил-2-оксо-3,4-дигидропиримидин-1(2н)-карбоксамидные производные
EP2938194B1 (en) * 2012-12-28 2019-11-27 Adama Makhteshim Ltd. N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2h)-carboxylate derivatives
UA117123C2 (uk) * 2012-12-28 2018-06-25 Адама Махтешім Лтд. Похідні 1-(заміщений бензоїл)-5-фтор-4-іміно-3-метил-3,4-дигідропіримідин-2(1h)-ону
CN112094262A (zh) 2012-12-31 2020-12-18 阿达玛马克西姆股份有限公司 作为杀真菌剂的化合物
CN106028816A (zh) 2013-12-31 2016-10-12 阿达玛马克西姆股份有限公司 用防治谷类中真菌的协同杀真菌混合物
NZ722438A (en) 2013-12-31 2018-01-26 Adama Makhteshim Ltd 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
KR20180080262A (ko) 2015-11-06 2018-07-11 사뮤메드, 엘엘씨 골관절염의 치료
SMT202200486T1 (it) 2016-06-01 2023-01-13 Biosplice Therapeutics Inc Processo per la preparazione di n-(5-(3-(7-(3- fluorofen il)-3h-imidaz0[4,5-c]piridin-2-il)-1h-indazol-5- il)piridin-3-il)-3-metilbutanammide
JP2020527563A (ja) 2017-07-17 2020-09-10 アダマ・マクテシム・リミテッド ５−フルオロ−４−イミノ−３−メチル−１−トシル−３，４−ジヒドロピリミジン−２−オンの多形体
CR20210270A (es) 2018-11-05 2021-07-20 Adama Makhteshim Ltd Mezclas y composiciones que comprenden 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2-ona, y métodos de uso de los mismos
AR120035A1 (es) 2019-09-23 2022-01-26 Adama Makhteshim Ltd Proceso para preparar 5-(fluoro-4-imino-3-metil)-1-tosil-3,4-dihidropirimidin-(1h)-ona y derivados del compuesto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3368938A (en) * 1966-01-13 1968-02-13 Hoffmann La Roche Controlling fungi with 5-fluorocytosine
DK0888359T3 (da) 1996-03-11 2002-08-12 Syngenta Participations Ag Pyrimidin-4-on-derivat som pesticid
WO2004037159A2 (en) * 2002-10-23 2004-05-06 Obetherapy Biotechnology Compounds, compositions and methods for modulating fat metabolism
SI2151439T1 (sl) * 2007-04-27 2014-05-30 Daiichi Sankyo Company, Limited Nitrogeniran aromatski derivat s 6-členskim obročem in farmacevtsko sredstvo, ki obsega ta derivat
MX2011001091A (es) 2008-08-01 2011-03-15 Dow Agrosciences Llc Uso de 5-fluorocitosina como un fungicida.

Also Published As

Publication number Publication date
IL217954A (en) 2016-02-29
IN2012DN00695A (enExample) 2015-06-19
RS53658B1 (sr) 2015-04-30
PL2462133T3 (pl) 2015-03-31
WO2011017544A1 (en) 2011-02-10
BR112012002807A2 (pt) 2015-10-13
CN102548979A (zh) 2012-07-04
NI201200019A (es) 2012-05-22
US20110034491A1 (en) 2011-02-10
JP2013501726A (ja) 2013-01-17
UA106086C2 (uk) 2014-07-25
DK2462133T3 (en) 2015-01-05
KR20120043069A (ko) 2012-05-03
NZ597638A (en) 2014-06-27
CL2012000314A1 (es) 2012-10-05
BR112012002807A8 (pt) 2017-07-11
AU2010279408B2 (en) 2015-09-10
CA2769251A1 (en) 2011-02-10
HK1172892A1 (en) 2013-05-03
AU2010279408A1 (en) 2012-02-09
CR20120033A (es) 2012-03-22
MX2012001623A (es) 2012-04-11
US8318758B2 (en) 2012-11-27
CO6491089A2 (es) 2012-07-31
KR101792286B1 (ko) 2017-10-31
PT2462133E (pt) 2014-12-26
EA022930B1 (ru) 2016-03-31
EP2462133A1 (en) 2012-06-13
CA2769251C (en) 2018-05-15
EP2462133A4 (en) 2013-01-16
ZA201305992B (en) 2014-10-29
EA201270255A1 (ru) 2012-07-30
ES2506169T3 (es) 2014-10-13
IL217954A0 (en) 2012-03-29
BR112012002807B1 (pt) 2018-07-10
EP2462133B1 (en) 2014-09-24
PE20120689A1 (es) 2012-06-06
ECSP12011651A (es) 2012-03-30
CN102548979B (zh) 2015-05-13
HN2012000261A (es) 2015-01-05

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