PE20110407A1 - Composicion farmaceutica que comprende una sal de estroncio, vitamina d y una ciclodextrina - Google Patents

Composicion farmaceutica que comprende una sal de estroncio, vitamina d y una ciclodextrina

Info

Publication number
PE20110407A1
PE20110407A1 PE2010001074A PE2010001074A PE20110407A1 PE 20110407 A1 PE20110407 A1 PE 20110407A1 PE 2010001074 A PE2010001074 A PE 2010001074A PE 2010001074 A PE2010001074 A PE 2010001074A PE 20110407 A1 PE20110407 A1 PE 20110407A1
Authority
PE
Peru
Prior art keywords
strontium
vitamin
cyclodextrin
pharmaceutical composition
beta
Prior art date
Application number
PE2010001074A
Other languages
English (en)
Inventor
Gilles Briault
Xavier Quenault
Cecile Poirier
Jean-Manuel Pean
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41719206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20110407(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of PE20110407A1 publication Critical patent/PE20110407A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) SAL DE ESTRONCIO SELECCIONADA DE RANELATO DE ESTRONCIO, MALONATO DE ESTRONCIO, L-ASCORBATO DE ESTRONCIO, GLUTAMATO DE ESTRONCIO, ENTRE OTROS, B) VITAMINA D TAL COMO COLECALCIFEROL EN UNA DOSIFICACION DE 1000 UI, C) BETA-CICLODEXTRINA SUSTITUIDA SELECCIONADA DE HPBCD (HIDROXIPROPIL-BETA.CICLODEXTRINAS), SBECD (SULFOBUTILETER-BETA-CICLODEXTRINAS), ENTRE OTRAS Y D) UNO O VARIOS EXCIPIENTES O VEHICULOS INERTES. LA RELACION MASICA ENTRE LA CANTIDAD DE VITAMINA D Y CICLODEXTRINA ESTA COMPRENDIDA ENTRE 1/40 Y 1/800. DICHA COMPOSICION ESTA EN FORMA DE COMPRIMIDOS PARA TRAGAR, PARA MASTICAR, COMPRIMIDOS EFERVESCENTES O EN FORMA DE GRANULOS PARA SOBRE SIENDO UTILES EN EL TRATAMIENTO DE ENFERMEDADES OSEAS O DE LA ARTROSIS
PE2010001074A 2009-11-27 2010-11-19 Composicion farmaceutica que comprende una sal de estroncio, vitamina d y una ciclodextrina PE20110407A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0905706A FR2953139B1 (fr) 2009-11-27 2009-11-27 Composition pharmaceutique comprenant un sel de strontium, de la vitamine d et une cyclodextrine

Publications (1)

Publication Number Publication Date
PE20110407A1 true PE20110407A1 (es) 2011-07-02

Family

ID=41719206

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2010001074A PE20110407A1 (es) 2009-11-27 2010-11-19 Composicion farmaceutica que comprende una sal de estroncio, vitamina d y una ciclodextrina

Country Status (31)

Country Link
US (1) US20110130370A1 (es)
EP (1) EP2335704A1 (es)
JP (1) JP2011111458A (es)
KR (1) KR101278935B1 (es)
CN (1) CN102078620A (es)
AP (1) AP2010005490A0 (es)
AR (1) AR079160A1 (es)
AU (1) AU2010241527B2 (es)
BR (1) BRPI1004685A2 (es)
CA (1) CA2723119C (es)
CL (1) CL2010001260A1 (es)
CO (1) CO6280058A1 (es)
CU (1) CU20100230A7 (es)
EA (1) EA018460B1 (es)
EC (1) ECSP10010622A (es)
FR (1) FR2953139B1 (es)
GE (1) GEP20135734B (es)
HN (1) HN2010002518A (es)
IL (1) IL209348A0 (es)
MA (1) MA32363B1 (es)
MX (1) MX2010012566A (es)
MY (1) MY158261A (es)
NZ (1) NZ589513A (es)
PE (1) PE20110407A1 (es)
SG (1) SG171542A1 (es)
SV (1) SV2010003744A (es)
TW (1) TW201200136A (es)
UA (1) UA105766C2 (es)
UY (1) UY33039A (es)
WO (1) WO2011064474A1 (es)
ZA (1) ZA201008230B (es)

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DK1993559T3 (en) 2006-02-03 2016-10-03 Opko Renal Llc Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
DK2481400T3 (da) 2007-04-25 2014-09-29 Opko Ip Holdings Ii Inc Orale præparater med kontrolleret frigivelse omfattende en vitamin D-forbindelse og en voksagtig bærer
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
LT2796457T (lt) 2009-11-27 2016-09-12 Genzyme Corporation Genz 112638, skirtas gošė arba fabri ligos gydymui kombinuota terapija
CN105796530A (zh) 2010-03-29 2016-07-27 赛特克罗公司 用于降低甲状旁腺水平的方法和组合物
CN102525975B (zh) * 2011-12-14 2013-06-19 天津药物研究院药业有限责任公司 雷奈酸锶口腔崩解片及其制备方法
CN102626420B (zh) * 2012-04-13 2014-06-25 深圳大学 一种含有锶、钙和维生素d的混合制剂
ES2505716T3 (es) * 2013-01-21 2015-09-04 Galenicum Health S.L. Composiciones farmacéuticas que comprenden una sal de ácido
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
CN103142623B (zh) * 2013-03-21 2014-04-16 青岛正大海尔制药有限公司 骨化三醇和雷尼酸锶的混悬颗粒及其制备方法
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
JP6706799B2 (ja) * 2014-12-19 2020-06-10 国立大学法人 長崎大学 新規ビスホスホン酸誘導体及びその用途
IL290855B2 (en) 2016-03-28 2024-06-01 Eirgen Pharma Ltd Treatment methods using vitamin D
US10463636B2 (en) * 2016-09-30 2019-11-05 Deanna J. Nelson Pharmaceutical quality strontium L-lactate
BR112019022455A2 (pt) * 2017-04-25 2020-05-12 Buck Institute For Research On Aging Formulações para prolongar o tempo de vida e de saúde
WO2019004984A2 (en) * 2017-05-29 2019-01-03 Biofarma Ilac Sanayi Ve Ticaret A.S. PHARMACEUTICAL FORMULATION COMPRISING CHOLECALCIFEROL
CN109276710A (zh) * 2018-11-23 2019-01-29 中国医学科学院药用植物研究所海南分所 一种增加骨密度的组合物及其制备方法和用途
CN112370429A (zh) * 2019-10-21 2021-02-19 广州富诺营养科技有限公司 一种直压型有机钙维生素d3咀嚼片及其制备方法
CN114452259A (zh) * 2021-07-28 2022-05-10 安徽旺盛添加剂有限公司 一种维生素d微囊钙片及其制备方法

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WO2005123130A2 (en) * 2004-06-17 2005-12-29 Osteologix A/S Improved treatments of rheumatic and arthritic diseases comprising combinations of a 5-lipoxygenase inhibitor
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ATE443541T1 (de) * 2004-06-25 2009-10-15 Strontin Aps Zusammensetzungen mit strontium und vitamin d und ihre verwendungen
CA2603235A1 (en) * 2005-03-28 2006-10-05 Bioresponse, Llc Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health
DE102005017775A1 (de) * 2005-04-13 2006-10-19 Schering Ag Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins
US20070218111A1 (en) * 2006-03-16 2007-09-20 Western Holdings, Llc Strontium compositions for bones
CN1823764A (zh) * 2006-03-27 2006-08-30 重庆医药工业研究院有限责任公司 一种含有雷奈酸锶和维生素d药物组合物
FR2899895B1 (fr) 2006-04-12 2010-09-17 Servier Lab Nouveaux sels de strontium d'acides sulfoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR100822133B1 (ko) * 2006-11-06 2008-04-15 한미약품 주식회사 비타민 ｄ 또는 이의 유도체의 고체분산체 및비스포스포네이트를 포함하는, 골다공증 예방 또는 치료용복합제제

Also Published As

Publication number Publication date
ECSP10010622A (es) 2011-06-30
AU2010241527B2 (en) 2013-12-19
FR2953139A1 (fr) 2011-06-03
US20110130370A1 (en) 2011-06-02
CO6280058A1 (es) 2011-05-20
CU20100230A7 (es) 2012-06-29
MY158261A (en) 2016-09-30
KR20110059546A (ko) 2011-06-02
TW201200136A (en) 2012-01-01
FR2953139B1 (fr) 2012-04-13
SV2010003744A (es) 2011-03-15
AP2010005490A0 (en) 2010-12-31
UY33039A (es) 2011-04-29
EA018460B1 (ru) 2013-08-30
HN2010002518A (es) 2012-09-03
SG171542A1 (en) 2011-06-29
AR079160A1 (es) 2011-12-28
GEP20135734B (en) 2013-01-25
NZ589513A (en) 2012-06-29
AU2010241527A1 (en) 2011-06-16
JP2011111458A (ja) 2011-06-09
UA105766C2 (uk) 2014-06-25
EA201001710A2 (ru) 2011-06-30
IL209348A0 (en) 2011-02-28
EA201001710A3 (ru) 2011-08-30
MA32363B1 (fr) 2011-06-01
WO2011064474A1 (fr) 2011-06-03
CA2723119A1 (fr) 2011-05-27
CA2723119C (fr) 2013-08-06
MX2010012566A (es) 2011-05-26
BRPI1004685A2 (pt) 2013-03-05
ZA201008230B (en) 2011-07-27
CL2010001260A1 (es) 2012-02-17
KR101278935B1 (ko) 2013-06-28
CN102078620A (zh) 2011-06-01
EP2335704A1 (fr) 2011-06-22

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