EA201001710A2 - Фармацевтическая композиция, которая содержит соль стронция, витамин d и циклодекстрин - Google Patents

Фармацевтическая композиция, которая содержит соль стронция, витамин d и циклодекстрин

Info

Publication number
EA201001710A2
EA201001710A2 EA201001710A EA201001710A EA201001710A2 EA 201001710 A2 EA201001710 A2 EA 201001710A2 EA 201001710 A EA201001710 A EA 201001710A EA 201001710 A EA201001710 A EA 201001710A EA 201001710 A2 EA201001710 A2 EA 201001710A2
Authority
EA
Eurasian Patent Office
Prior art keywords
cyclodextrin
vitamin
pharmaceutical composition
contains salt
salt strontium
Prior art date
Application number
EA201001710A
Other languages
English (en)
Other versions
EA018460B1 (ru
EA201001710A3 (ru
Inventor
Жиль Бриоль
Ксавье Кеноль
Сесиль Пойрье
Жан-Маньюэль Пеан
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41719206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201001710(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA201001710A2 publication Critical patent/EA201001710A2/ru
Publication of EA201001710A3 publication Critical patent/EA201001710A3/ru
Publication of EA018460B1 publication Critical patent/EA018460B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

Фармацевтическая композиция, которая содержит соль стронция, витамин D и циклодекстрин.
EA201001710A 2009-11-27 2010-11-26 Фармацевтическая композиция, которая содержит соль стронция, витамин d и циклодекстрин EA018460B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0905706A FR2953139B1 (fr) 2009-11-27 2009-11-27 Composition pharmaceutique comprenant un sel de strontium, de la vitamine d et une cyclodextrine

Publications (3)

Publication Number Publication Date
EA201001710A2 true EA201001710A2 (ru) 2011-06-30
EA201001710A3 EA201001710A3 (ru) 2011-08-30
EA018460B1 EA018460B1 (ru) 2013-08-30

Family

ID=41719206

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001710A EA018460B1 (ru) 2009-11-27 2010-11-26 Фармацевтическая композиция, которая содержит соль стронция, витамин d и циклодекстрин

Country Status (31)

Country Link
US (1) US20110130370A1 (ru)
EP (1) EP2335704A1 (ru)
JP (1) JP2011111458A (ru)
KR (1) KR101278935B1 (ru)
CN (1) CN102078620A (ru)
AP (1) AP2010005490A0 (ru)
AR (1) AR079160A1 (ru)
AU (1) AU2010241527B2 (ru)
BR (1) BRPI1004685A2 (ru)
CA (1) CA2723119C (ru)
CL (1) CL2010001260A1 (ru)
CO (1) CO6280058A1 (ru)
CU (1) CU20100230A7 (ru)
EA (1) EA018460B1 (ru)
EC (1) ECSP10010622A (ru)
FR (1) FR2953139B1 (ru)
GE (1) GEP20135734B (ru)
HN (1) HN2010002518A (ru)
IL (1) IL209348A0 (ru)
MA (1) MA32363B1 (ru)
MX (1) MX2010012566A (ru)
MY (1) MY158261A (ru)
NZ (1) NZ589513A (ru)
PE (1) PE20110407A1 (ru)
SG (1) SG171542A1 (ru)
SV (1) SV2010003744A (ru)
TW (1) TW201200136A (ru)
UA (1) UA105766C2 (ru)
UY (1) UY33039A (ru)
WO (1) WO2011064474A1 (ru)
ZA (1) ZA201008230B (ru)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1993559T3 (pl) 2006-02-03 2017-01-31 Opko Renal, Llc Leczenie niedoboru i deficytu witaminy d z zastosowaniem 25-hydroksywitaminy d2 i 25-hydroksywitaminy d3
LT2679228T (lt) 2006-06-21 2018-05-10 Opko Ireland Global Holdings, Ltd. Terapija naudojant vitamino d atstatymo agentą ir vitamino d hormoninį pakaitinį agentą
WO2008134512A1 (en) 2007-04-25 2008-11-06 Cytochroma Inc. Oral controlled release compositions comprising vitamin d compound and waxy carrier
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
PT3133070T (pt) 2009-11-27 2019-11-11 Genzyme Corp Eliglustat (genz 112638) como inibidor de glicosilceramida-sintase para utilização num método de tratamento de doença de fabry ou de gaucher, o método compreendendo ajustar a dose terapêutica individual ao metabolismo do p-450 do doente
KR102125424B1 (ko) 2010-03-29 2020-06-22 사이토크로마 인코포레이티드 부갑상선 수준을 낮추기 위한 방법 및 조성물
CN102525975B (zh) * 2011-12-14 2013-06-19 天津药物研究院药业有限责任公司 雷奈酸锶口腔崩解片及其制备方法
CN102626420B (zh) * 2012-04-13 2014-06-25 深圳大学 一种含有锶、钙和维生素d的混合制剂
ES2505716T3 (es) * 2013-01-21 2015-09-04 Galenicum Health S.L. Composiciones farmacéuticas que comprenden una sal de ácido
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
CN103142623B (zh) * 2013-03-21 2014-04-16 青岛正大海尔制药有限公司 骨化三醇和雷尼酸锶的混悬颗粒及其制备方法
CR20170085A (es) 2014-08-07 2017-04-25 Opko Ireland Global Holdings Ltd Terapia adjuntiva con 25-hidroxi vitamina d
WO2016098904A1 (ja) * 2014-12-19 2016-06-23 国立大学法人 長崎大学 新規ビスホスホン酸誘導体及びその用途
JP7032322B2 (ja) 2016-03-28 2022-03-08 オプコ アイルランド グローバル ホールディングス リミテッド ビタミンｄ治療法
US10463636B2 (en) * 2016-09-30 2019-11-05 Deanna J. Nelson Pharmaceutical quality strontium L-lactate
SG10202107237SA (en) * 2017-04-25 2021-08-30 Buck Inst Res Aging Formulations for extending lifespan and healthspan
WO2019004984A2 (en) * 2017-05-29 2019-01-03 Biofarma Ilac Sanayi Ve Ticaret A.S. PHARMACEUTICAL FORMULATION COMPRISING CHOLECALCIFEROL
CN109276710A (zh) * 2018-11-23 2019-01-29 中国医学科学院药用植物研究所海南分所 一种增加骨密度的组合物及其制备方法和用途
CN112370429A (zh) * 2019-10-21 2021-02-19 广州富诺营养科技有限公司 一种直压型有机钙维生素d3咀嚼片及其制备方法
CN114452259A (zh) * 2021-07-28 2022-05-10 安徽旺盛添加剂有限公司 一种维生素d微囊钙片及其制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52130904A (en) * 1976-04-26 1977-11-02 Teijin Ltd Stabilization of vitamin d#
HU177586B (en) * 1978-12-19 1981-11-28 Chinoin Gyogyszer Es Vegyeszet New process for preparing stable inclusion complexes of vitamine d with cyclodextrin
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
FR2651497B1 (fr) 1989-09-01 1991-10-25 Adir Nouveaux sels de metaux bivalents de l'acide n, n-di (carboxymethyl)amino-2 cyano-3 carboxymethyl-4 carboxy-5 thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.
CN1110275A (zh) * 1994-04-06 1995-10-18 福建省药品检验所 一种维生素D与羟丙基-β-环糊精的包合物
FR2749759B1 (fr) 1996-06-17 1999-11-26 Adir Utilisation de sels de strontium pour l'obtention de compositions pharmaceutiques destinees au traitement de l'arthrose
JP2003514925A (ja) * 1999-11-12 2003-04-22 ピサ・アンド・ピサ・エルエルシー ベータ−シクロデキストリン及び関連化合物の部分メチルエーテルの結晶性混合物
WO2001048024A1 (en) * 1999-12-23 2001-07-05 Cerestar Holding B.V. Stabilized cyclodextrin complexes
JP2003268005A (ja) * 2002-03-14 2003-09-25 Medorekkusu:Kk 包接体の製造法
SI1622630T1 (sl) * 2003-05-07 2012-12-31 Osteologix A/S Stroncijeva kombinacije za profilakso/zdravljenje patologij hrustanca in/ali kosti
AU2004237437B2 (en) * 2003-05-07 2011-01-20 Osteologix A/S Controlled release composition containing a strontium salt
DK1534305T3 (da) 2003-05-07 2007-02-05 Osteologix As Behandling af brusk-/knoglelidelser med vandoplöselige strontiumsalte
CN100374632C (zh) * 2003-05-30 2008-03-12 三井化学株式会社 人造毛发用纤维
CA2531136A1 (en) * 2003-07-04 2005-01-13 Nycomed Danmark Aps Parathyroid hormone (pth) containing pharmaceutical compositions for oral use
WO2005123130A2 (en) * 2004-06-17 2005-12-29 Osteologix A/S Improved treatments of rheumatic and arthritic diseases comprising combinations of a 5-lipoxygenase inhibitor
CN101018586B (zh) * 2004-06-25 2014-08-27 莫克瓦洛Spf有限公司 含锶和维生素d的组合物及其用途
MXPA06015187A (es) * 2004-06-25 2007-09-27 Strontin Aps Composiciones que comprenden estroncio y vitamina d y usos de las mismas.
CA2603235A1 (en) * 2005-03-28 2006-10-05 Bioresponse, Llc Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health
DE102005017775A1 (de) * 2005-04-13 2006-10-19 Schering Ag Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins
US20070218111A1 (en) * 2006-03-16 2007-09-20 Western Holdings, Llc Strontium compositions for bones
CN1823764A (zh) * 2006-03-27 2006-08-30 重庆医药工业研究院有限责任公司 一种含有雷奈酸锶和维生素d药物组合物
FR2899895B1 (fr) 2006-04-12 2010-09-17 Servier Lab Nouveaux sels de strontium d'acides sulfoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR100822133B1 (ko) * 2006-11-06 2008-04-15 한미약품 주식회사 비타민 ｄ 또는 이의 유도체의 고체분산체 및비스포스포네이트를 포함하는, 골다공증 예방 또는 치료용복합제제

Also Published As

Publication number Publication date
NZ589513A (en) 2012-06-29
EA018460B1 (ru) 2013-08-30
CA2723119C (fr) 2013-08-06
MA32363B1 (fr) 2011-06-01
AU2010241527A1 (en) 2011-06-16
PE20110407A1 (es) 2011-07-02
SG171542A1 (en) 2011-06-29
MX2010012566A (es) 2011-05-26
AU2010241527B2 (en) 2013-12-19
KR20110059546A (ko) 2011-06-02
JP2011111458A (ja) 2011-06-09
UY33039A (es) 2011-04-29
FR2953139A1 (fr) 2011-06-03
AR079160A1 (es) 2011-12-28
WO2011064474A1 (fr) 2011-06-03
AP2010005490A0 (en) 2010-12-31
IL209348A0 (en) 2011-02-28
CA2723119A1 (fr) 2011-05-27
ZA201008230B (en) 2011-07-27
KR101278935B1 (ko) 2013-06-28
EA201001710A3 (ru) 2011-08-30
FR2953139B1 (fr) 2012-04-13
CO6280058A1 (es) 2011-05-20
ECSP10010622A (es) 2011-06-30
TW201200136A (en) 2012-01-01
SV2010003744A (es) 2011-03-15
BRPI1004685A2 (pt) 2013-03-05
GEP20135734B (en) 2013-01-25
US20110130370A1 (en) 2011-06-02
CN102078620A (zh) 2011-06-01
UA105766C2 (ru) 2014-06-25
HN2010002518A (es) 2012-09-03
EP2335704A1 (fr) 2011-06-22
CU20100230A7 (es) 2012-06-29
MY158261A (en) 2016-09-30
CL2010001260A1 (es) 2012-02-17

Similar Documents

Publication Publication Date Title
EA201001710A2 (ru) Фармацевтическая композиция, которая содержит соль стронция, витамин d и циклодекстрин
BRPI1010768A2 (pt) composto, e, composição farmacêutica.
CL2012002979A1 (es) Derivados de n3-sustituido-n1-sulfonil-5-fluorpirimidinona.
EA201300146A1 (ru) ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ МОДУЛЯТОРА c-МЕТ
BR112015003259A2 (pt) composto, composição farmacêutica, e, composição de vacina.
EA201200617A1 (ru) Полимеры на основе циклодекстрина для доставки лекарственных средств
BRPI1016190A2 (pt) compostos farmacêuticos.
BR112014025041B8 (pt) Composição farmacêutica
BR112013003536A2 (pt) composição, e utilização de uma composição.
BR112012003800A2 (pt) composição, peptídeo, e formulação farmacêutica.
BR112013019327A2 (pt) composto, e, composição.
BR112014009889A2 (pt) compostos dissubstituídos, compostos e composição farmacêutica
EA201490761A1 (ru) R(+)-n-формилпропаргиламиноиндан
BR112012000831A2 (pt) compostos, composições farmacêuticas e métodos relacionados
FR2966719B1 (fr) Implant glenoidien.
IT1398070B1 (it) Proiettore da palcoscenico.
CL2009001973S1 (es) Mostrador.
CO6761388A2 (es) Composiciones pharmaceuticas que comprenden alisporivir
TR200900882A2 (tr) Tadı ve kokusu maskelenmiş, bıyoyararlanımı yüksek farmasotık bileşimler.
BR112014032501A2 (pt) composto, e, composição farmacêutica.
IT1399492B1 (it) Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina.
EA201301355A1 (ru) Композиция и таблетка, содержащая ралтегравир
BRPI0811431A2 (pt) Composição farmacêutica aquosa.
BR112013016029A2 (pt) composição farmacêutica de fosfomicina.
BR112013015701A2 (pt) derivado de sulfeto difelina, medicamento e composição farmacêutica contendo o referido derivado

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU