PE20070074A1 - Formulaciones de diclofenaco - Google Patents

Formulaciones de diclofenaco

Info

Publication number
PE20070074A1
PE20070074A1 PE2006000678A PE2006000678A PE20070074A1 PE 20070074 A1 PE20070074 A1 PE 20070074A1 PE 2006000678 A PE2006000678 A PE 2006000678A PE 2006000678 A PE2006000678 A PE 2006000678A PE 20070074 A1 PE20070074 A1 PE 20070074A1
Authority
PE
Peru
Prior art keywords
formulation
diclofenac formulations
migrana
dichlofenac
preference
Prior art date
Application number
PE2006000678A
Other languages
English (en)
Inventor
Giorgio Reiner
Alberto Reiner
Andreas Meyer
Original Assignee
Applied Pharma Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37396065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20070074(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Pharma Res filed Critical Applied Pharma Res
Publication of PE20070074A1 publication Critical patent/PE20070074A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

REFERIDA A UNA FORMULACION FARMACEUTICA, EN POLVO O LIQUIDA, QUE CONTIENE 50 MG DE DICLOFENACO O UNA SAL DEL MISMO. DICHA FORMULACION PUEDE CONTENER MANITOL FINO Y/O GRUESO, UN BICARBONATO DE METAL ALCALINO, DE PREFERENCIA BICARBONATO DE POTASIO, DIBEHENATO DE GLICERILO, AGUA, ALCOHOL ETILICO. DICHA FORMULACION ES UTIL EN EL TRATAMIENTO DE LA MIGRANA Y SINTOMAS QUE LO ACOMPANAN, DOLOR AGUDO, ENTRE OTROS
PE2006000678A 2005-06-17 2006-06-16 Formulaciones de diclofenaco PE20070074A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69175705P 2005-06-17 2005-06-17
US69202405P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
PE20070074A1 true PE20070074A1 (es) 2007-02-08

Family

ID=37396065

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000678A PE20070074A1 (es) 2005-06-17 2006-06-16 Formulaciones de diclofenaco

Country Status (24)

Country Link
US (7) US7759394B2 (es)
EP (4) EP2402003B1 (es)
KR (1) KR101352130B1 (es)
CN (3) CN101272768A (es)
AR (1) AR057378A1 (es)
AU (1) AU2006257072B2 (es)
BR (1) BRPI0612245A2 (es)
CA (2) CA2932603C (es)
EC (1) ECSP077989A (es)
ES (3) ES2912897T3 (es)
GT (1) GT200600261A (es)
HK (1) HK1213814A1 (es)
JO (1) JO3352B1 (es)
MX (1) MX2007016072A (es)
NO (1) NO342336B1 (es)
NZ (1) NZ564002A (es)
PE (1) PE20070074A1 (es)
PL (1) PL1890680T3 (es)
PT (1) PT1890680T (es)
RU (1) RU2432160C2 (es)
TR (1) TR201706038T4 (es)
TW (1) TW200740470A (es)
WO (1) WO2006133954A2 (es)
ZA (1) ZA200710858B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974595B1 (en) * 1996-05-17 2005-12-13 Proethic Pharmaceuticals, Inc. Pharmaceutical compositions based on Diclofenae
JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
US7700125B2 (en) * 2006-02-07 2010-04-20 Kowa Pharmaceuticals America, Inc. Moisture resistant container systems for rapidly bioavailable dosage forms
MX2009012458A (es) * 2007-05-24 2009-12-02 Novartis Ag Forma de dosificacion oral que permite una rapida absorcion de un farmaco.
SG175315A1 (en) 2009-04-24 2011-11-28 Iceutica Pty Ltd A novel formulation of indomethacin
CN106420667A (zh) 2009-04-24 2017-02-22 伊休蒂卡有限公司 双氯芬酸的新剂型
EP2480212B1 (en) * 2009-09-25 2016-07-06 Novartis Consumer Health S.A. Oral pharmaceutical composition comprising diclofenac
FR2984165B1 (fr) * 2011-12-16 2014-06-27 Pharmeuro Traitement des crises de migraines, notamment d'algies vasculaires de la face
US9526734B2 (en) 2014-06-09 2016-12-27 Iceutica Pty Ltd. Formulation of meloxicam
US9855234B2 (en) 2014-07-08 2018-01-02 Insys Development Company, Inc. Diclofenac sublingual spray
CN106580886A (zh) * 2016-12-05 2017-04-26 北京万全德众医药生物技术有限公司 一种双氯芬酸钾散剂及其制备方法
WO2019030773A1 (en) * 2017-08-10 2019-02-14 Sarudbhava Formulations Private Limited DICLOFENAC COMPOSITIONS WITH LOW DOSE
US11260026B2 (en) 2018-12-14 2022-03-01 Apr Applied Pharma Research Sa Ready to use diclofenac stick packs
EP4164612A1 (en) 2020-06-10 2023-04-19 Apr Applied Pharma Research S.A. Bioavailable sugar-based diclofenac formulations
EP3928766A1 (en) 2020-06-26 2021-12-29 Usso Barnas Pharmaceutical composition and use thereof
CN115317464B (zh) * 2022-09-01 2023-08-08 苏州弘森药业股份有限公司 一种双氯芬酸钾微胶囊及其制备方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
US4344929A (en) 1980-04-25 1982-08-17 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
JPS57191962A (en) 1981-05-20 1982-11-25 Hitachi Ltd Fuel cell
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
CH673395A5 (es) * 1987-01-30 1990-03-15 Ciba Geigy Ag
US5211957A (en) 1988-03-25 1993-05-18 Ciba-Geigy Corporation Solid rapidly disintegrating dosage form
IT1226549B (it) 1988-07-12 1991-01-24 Resa Farma Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose.
GB8824392D0 (en) 1988-10-18 1988-11-23 Ciba Geigy Ag Dispersible formulation
GB8920693D0 (en) 1989-09-13 1989-10-25 Nicholas Kiwi Pty Ltd Non-effervescent ibuprofen compositions
EP0466640B1 (de) 1990-06-28 1995-05-24 Ciba-Geigy Ag Alpha-Carbonylphenylacetonitrilderivate als Stabilisatoren für organische Materialien
EP0466650A2 (en) 1990-07-11 1992-01-15 Warner-Lambert Company Improvements in non-steroidal anti-inflammatory therapy
MX9300110A (es) 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
CA2141582C (en) 1992-08-05 2003-09-30 Angelo Mario Morella Pelletised pharmaceutical composition
IT1264696B1 (it) 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
EP0867426B1 (de) 1993-09-07 2002-06-26 Gerhard Dr. Gergely Modifizierte Kristalle einer festen, essbaren, organischen Säure
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
JPH10500982A (ja) 1994-05-27 1998-01-27 ファーマーク、ネダーランド、ベスローテン、フェンノートシャップ 医薬組成物
ZA959469B (en) 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
IT1283029B1 (it) * 1996-05-17 1998-04-03 Resa Farma Composizioni farmaceutiche a base di diclofenac
DE19538555A1 (de) 1995-10-17 1997-04-24 Beiersdorf Ag Gegen Akne und entzündete Comedonen wirksame Wirkstoffkombinationen
JP2000508649A (ja) * 1996-04-16 2000-07-11 ノバルティス・コンシューマー・ヘルス・ソシエテ・アノニム 速崩解性経口剤形物
US7687542B2 (en) * 1996-05-17 2010-03-30 Kowa Pharmaeuticals America, Inc. Rapidly bioavailable tablet and capsule formulations of diclofenac
US6974595B1 (en) * 1996-05-17 2005-12-13 Proethic Pharmaceuticals, Inc. Pharmaceutical compositions based on Diclofenae
US20060013896A1 (en) * 1996-05-17 2006-01-19 Giorgio Reiner Methods of treating acute pain using diclofenac
US5854279A (en) 1996-06-04 1998-12-29 Eisai Co., Ltd Therapeutic agent for dermatosis
US5914129A (en) 1996-07-23 1999-06-22 Mauskop; Alexander Analgesic composition for treatment of migraine headaches
US6586458B1 (en) 1996-08-16 2003-07-01 Pozen Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US5788987A (en) 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
JP5026635B2 (ja) 1998-09-10 2012-09-12 ニュコメデ ダンマルク アンパーツセルスカブ 医薬物質の迅速放出医薬組成物
ES2199916T3 (es) * 2001-11-20 2004-03-01 Apr Applied Pharma Research S.A. Composiciones farmaceuticas hidrosolubles no efervescentes que comprenden farmacos antiinflamatorios no esteroideos.
CA2524773C (en) * 2003-05-08 2014-04-08 Nektar Therapeutics Uk Ltd Particulate coformulations of active substances with excipients
JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
US7939561B2 (en) * 2006-02-07 2011-05-10 Apr Applied Pharma Research S.A. Blister packaging for acute pain regimens
US7700125B2 (en) * 2006-02-07 2010-04-20 Kowa Pharmaceuticals America, Inc. Moisture resistant container systems for rapidly bioavailable dosage forms

Also Published As

Publication number Publication date
PL1890680T3 (pl) 2017-08-31
ES2641889T3 (es) 2017-11-14
CA2932603A1 (en) 2006-12-21
GT200600261A (es) 2007-02-05
EP2402003A3 (en) 2012-05-09
PT1890680T (pt) 2017-05-05
JO3352B1 (ar) 2019-03-13
RU2432160C2 (ru) 2011-10-27
RU2008101784A (ru) 2009-07-27
EP1890680B1 (en) 2017-03-08
US7759394B2 (en) 2010-07-20
US8927604B2 (en) 2015-01-06
EP2705837A1 (en) 2014-03-12
MX2007016072A (es) 2008-03-10
US20090197961A1 (en) 2009-08-06
EP2705837B1 (en) 2019-02-20
US20170319484A1 (en) 2017-11-09
US20100204330A1 (en) 2010-08-12
US20150064258A1 (en) 2015-03-05
KR101352130B1 (ko) 2014-02-06
CN104856959A (zh) 2015-08-26
US20200323776A1 (en) 2020-10-15
US9827197B2 (en) 2017-11-28
CN112755014A (zh) 2021-05-07
ES2912897T3 (es) 2022-05-30
AU2006257072A1 (en) 2006-12-21
CN101272768A (zh) 2008-09-24
BRPI0612245A2 (pt) 2010-10-26
CA2632375A1 (en) 2006-12-21
ES2717879T3 (es) 2019-06-26
US8097651B2 (en) 2012-01-17
US20130245122A1 (en) 2013-09-19
TR201706038T4 (tr) 2019-02-21
NO20080352L (no) 2008-03-17
CA2632375C (en) 2016-08-16
ECSP077989A (es) 2008-03-26
AU2006257072B2 (en) 2012-08-16
EP1890680A2 (en) 2008-02-27
HK1213814A1 (zh) 2016-07-15
AR057378A1 (es) 2007-11-28
CA2932603C (en) 2017-08-08
EP2402003B1 (en) 2020-05-06
WO2006133954A3 (en) 2007-07-26
WO2006133954A2 (en) 2006-12-21
KR20080024202A (ko) 2008-03-17
EP3103441B1 (en) 2022-03-16
NO342336B1 (no) 2018-05-07
EP3103441A1 (en) 2016-12-14
ZA200710858B (en) 2008-12-31
NZ564002A (en) 2011-03-31
TW200740470A (en) 2007-11-01
US20070015831A1 (en) 2007-01-18
EP2402003A2 (en) 2012-01-04

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