PE20071310A1 - Formulaciones liquidas de fenilefrina - Google Patents

Formulaciones liquidas de fenilefrina

Info

Publication number
PE20071310A1
PE20071310A1 PE2007000185A PE2007000185A PE20071310A1 PE 20071310 A1 PE20071310 A1 PE 20071310A1 PE 2007000185 A PE2007000185 A PE 2007000185A PE 2007000185 A PE2007000185 A PE 2007000185A PE 20071310 A1 PE20071310 A1 PE 20071310A1
Authority
PE
Peru
Prior art keywords
composition
liquid
phenylephrine
glycerin
sorbitol
Prior art date
Application number
PE2007000185A
Other languages
English (en)
Inventor
William Bubnis
Stephanie Shield
Amanda Alley
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PE20071310A1 publication Critical patent/PE20071310A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

REFERIDA A UNA COMPOSICION ACUOSA ORAL QUE COMPRENDE: FENILEFRINA, ENDULZANTE ARTIFICIAL, HASTA 45% P/V DE GLICERINA, HASTA 10% P/V DE SORBITOL; DONDE LA PROPORCION DE GLICERINA A SORBITOL ESTA ENTRE 2:1 Y 10:1. EL ENDULZANTE ARTIFICIAL SE SELECCIONA DE SUCRALOSA, SALES DE SACARINA, CICLAMATOS, ACESULFAME DE POTASIO, ASPARTAME Y MEZCLA DE ELLOS. LA COMPOSICION PUEDE INCLUIR UN SEGUNDO COMPUESTO ACTIVO TAL COMO ACETAMINOFEN, DIFENHIDRAMINA, DEXTROMETORFANO, ENTRE OTROS; ASI COMO UN AGENTE PRESERVANTE TAL COMO BENZOATO DE SODIO, SORBATOS, PARABENOS, EDTA O MEZCLAS DE ELLOS; UN ANTIOXIDANTE TAL COMO GALATO DE PROPILO. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DEL RESFRIADO
PE2007000185A 2006-02-21 2007-02-20 Formulaciones liquidas de fenilefrina PE20071310A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77463406P 2006-02-21 2006-02-21

Publications (1)

Publication Number Publication Date
PE20071310A1 true PE20071310A1 (es) 2007-12-12

Family

ID=38283964

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2007000185A PE20071310A1 (es) 2006-02-21 2007-02-20 Formulaciones liquidas de fenilefrina
PE2010001013A PE20110010A1 (es) 2006-02-21 2007-02-20 Formulaciones liquidas de fenilefrina

Family Applications After (1)

Application Number Title Priority Date Filing Date
PE2010001013A PE20110010A1 (es) 2006-02-21 2007-02-20 Formulaciones liquidas de fenilefrina

Country Status (12)

Country Link
US (4) US8940796B2 (es)
EP (2) EP2316425B1 (es)
AU (1) AU2007217799B2 (es)
CA (1) CA2642048C (es)
ES (2) ES2692890T3 (es)
HU (2) HUE043620T2 (es)
PE (2) PE20071310A1 (es)
PL (2) PL1986606T3 (es)
PT (2) PT2316425T (es)
TR (2) TR201815803T4 (es)
TW (1) TWI482620B (es)
WO (1) WO2007098128A2 (es)

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US8940796B2 (en) 2006-02-21 2015-01-27 Wyeth Llc Phenylephrine liquid formulations
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
US20070249727A1 (en) * 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
US20070254027A1 (en) 2006-04-28 2007-11-01 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
CA2653955C (en) * 2006-06-01 2015-10-27 Schering Corporation Pharmaceutical compositions for sustained release of phenylephrine
TW200808376A (en) * 2006-06-01 2008-02-16 Schering Corp Phenylephrine pulsed release formulations and pharmaceutical compositions
NZ573174A (en) * 2006-06-01 2012-01-12 Msd Consumer Care Inc Sustained release pharmaceutical dosage form containing phenylephrine
NZ573173A (en) * 2006-06-01 2012-03-30 Msd Consumer Care Inc Phenylephrine pharmaceutical formulation and compositions for colonic absorption
CN101848706A (zh) * 2007-06-01 2010-09-29 先灵-普劳健康护理产品公司 包含底物和含活性成分和聚乙烯醇的包衣的药用组合物
PE20091084A1 (es) * 2007-12-07 2009-07-23 Schering Plough Healthcare Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal
CA2919892C (en) 2013-08-12 2019-06-18 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015137829A1 (en) * 2014-03-12 2015-09-17 Angeles Relinda G Stable and palatable liquid pharmaceutical composition of phenylephrine and a maleate salt of an antihistamine
AU2015290098B2 (en) 2014-07-17 2018-11-01 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
CA2964628A1 (en) 2014-10-20 2016-04-28 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
CN104983732B (zh) * 2015-05-28 2018-05-04 华润三九医药股份有限公司 一种布洛肾素那敏片及其制备方法
CN104922124B (zh) * 2015-05-28 2017-06-30 华润三九医药股份有限公司 一种肾素那敏片及其制备方法
EP3820440A1 (en) * 2018-07-09 2021-05-19 Bayer HealthCare, LLC An aqueous-based composition containing xantan gum as inhibitor of microbial growth
CN109125257B (zh) * 2018-10-18 2020-12-01 云南大唐汉方制药股份有限公司 氨酚愈创肾素口服液及其制备方法
CN109044968B (zh) * 2018-10-18 2020-12-01 云南大唐汉方制药股份有限公司 氨酚右美肾素口服液及其制备方法
CN109045003B (zh) * 2018-10-18 2020-12-01 云南大唐汉方制药股份有限公司 氨酚拉明肾素口服液及其制备方法
CN110327339A (zh) * 2019-08-07 2019-10-15 北京博达绿洲医药科技研究有限公司 一种复方右美沙芬口服溶液及其制备方法和用途
CN110507607A (zh) * 2019-09-27 2019-11-29 葵花药业集团北京药物研究院有限公司 苯海拉明肾素口服液及其制备方法和用途
HUE065040T2 (hu) 2019-12-23 2024-04-28 Nutra Essential Otc S L Ibuprofént és fenilefrint tartalmazó folyékony készítmény
WO2021150747A1 (en) * 2020-01-22 2021-07-29 Nevakar Inc. Phenylephrine hydrochloride compositions and containers
CN111450051B (zh) * 2020-04-21 2022-03-18 武汉贝参药业股份有限公司 一种富马酸酮替芬口服溶液的制备方法
CN112076183A (zh) * 2020-08-28 2020-12-15 北京博达绿洲医药科技研究有限公司 包含盐酸去氧肾上腺素液体组合物
CN113081958B (zh) * 2021-05-01 2022-05-03 安徽新世纪药业有限公司 一种地氯雷他定口服溶液及其制备方法

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US20070254027A1 (en) * 2006-04-28 2007-11-01 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
TW200808376A (en) 2006-06-01 2008-02-16 Schering Corp Phenylephrine pulsed release formulations and pharmaceutical compositions

Also Published As

Publication number Publication date
WO2007098128A2 (en) 2007-08-30
US8940796B2 (en) 2015-01-27
HUE043620T2 (hu) 2019-08-28
PT2316425T (pt) 2018-11-13
ES2692890T3 (es) 2018-12-05
WO2007098128A3 (en) 2007-10-11
US20170333561A1 (en) 2017-11-23
EP2316425B1 (en) 2018-08-29
PE20110010A1 (es) 2011-01-12
US11419938B2 (en) 2022-08-23
TR201815803T4 (tr) 2018-11-21
EP1986606B1 (en) 2019-04-10
US9801941B2 (en) 2017-10-31
HUE039382T2 (hu) 2018-12-28
US11406712B2 (en) 2022-08-09
TR201906970T4 (tr) 2019-06-21
EP2316425A1 (en) 2011-05-04
AU2007217799B2 (en) 2012-12-13
US20190209688A1 (en) 2019-07-11
AU2007217799A1 (en) 2007-08-30
PT1986606T (pt) 2019-06-12
PL2316425T3 (pl) 2019-01-31
CA2642048A1 (en) 2007-08-30
TW200800143A (en) 2008-01-01
TWI482620B (zh) 2015-05-01
CA2642048C (en) 2015-11-24
US20070197661A1 (en) 2007-08-23
EP1986606A2 (en) 2008-11-05
US20150150976A1 (en) 2015-06-04
PL1986606T3 (pl) 2019-08-30
ES2728823T3 (es) 2019-10-28

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