TW200740470A - Diclofenac formulations and methods of use - Google Patents

Diclofenac formulations and methods of use

Info

Publication number
TW200740470A
TW200740470A TW095120788A TW95120788A TW200740470A TW 200740470 A TW200740470 A TW 200740470A TW 095120788 A TW095120788 A TW 095120788A TW 95120788 A TW95120788 A TW 95120788A TW 200740470 A TW200740470 A TW 200740470A
Authority
TW
Taiwan
Prior art keywords
methods
formulations
diclofenac
acute pain
diclofenac formulations
Prior art date
Application number
TW095120788A
Other languages
English (en)
Inventor
Giorgio Reiner
Alberto Reiner
Andreas Meyer
Original Assignee
Apr Applied Pharma Res Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37396065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200740470(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Apr Applied Pharma Res Sa filed Critical Apr Applied Pharma Res Sa
Publication of TW200740470A publication Critical patent/TW200740470A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
TW095120788A 2005-06-17 2006-06-12 Diclofenac formulations and methods of use TW200740470A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69202405P 2005-06-17 2005-06-17
US69175705P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
TW200740470A true TW200740470A (en) 2007-11-01

Family

ID=37396065

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095120788A TW200740470A (en) 2005-06-17 2006-06-12 Diclofenac formulations and methods of use

Country Status (24)

Country Link
US (7) US7759394B2 (zh)
EP (4) EP3103441B1 (zh)
KR (1) KR101352130B1 (zh)
CN (3) CN101272768A (zh)
AR (1) AR057378A1 (zh)
AU (1) AU2006257072B2 (zh)
BR (1) BRPI0612245A2 (zh)
CA (2) CA2932603C (zh)
EC (1) ECSP077989A (zh)
ES (3) ES2717879T3 (zh)
GT (1) GT200600261A (zh)
HK (1) HK1213814A1 (zh)
JO (1) JO3352B1 (zh)
MX (1) MX2007016072A (zh)
NO (1) NO342336B1 (zh)
NZ (1) NZ564002A (zh)
PE (1) PE20070074A1 (zh)
PL (1) PL1890680T3 (zh)
PT (1) PT1890680T (zh)
RU (1) RU2432160C2 (zh)
TR (1) TR201706038T4 (zh)
TW (1) TW200740470A (zh)
WO (1) WO2006133954A2 (zh)
ZA (1) ZA200710858B (zh)

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US6974595B1 (en) * 1996-05-17 2005-12-13 Proethic Pharmaceuticals, Inc. Pharmaceutical compositions based on Diclofenae
JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
US7700125B2 (en) * 2006-02-07 2010-04-20 Kowa Pharmaceuticals America, Inc. Moisture resistant container systems for rapidly bioavailable dosage forms
NZ579972A (en) * 2007-05-24 2012-03-30 Novartis Ag Oral dosage form of diclofenac providing fast absorption of drug
CN103932988A (zh) 2009-04-24 2014-07-23 伊休蒂卡有限公司 吲哚美辛的新剂型
NZ595987A (en) 2009-04-24 2014-02-28 Iceutica Pty Ltd A novel formulation of diclofenac
EP2480212B1 (en) * 2009-09-25 2016-07-06 Novartis Consumer Health S.A. Oral pharmaceutical composition comprising diclofenac
FR2984165B1 (fr) * 2011-12-16 2014-06-27 Pharmeuro Traitement des crises de migraines, notamment d'algies vasculaires de la face
US9526734B2 (en) 2014-06-09 2016-12-27 Iceutica Pty Ltd. Formulation of meloxicam
US9855234B2 (en) 2014-07-08 2018-01-02 Insys Development Company, Inc. Diclofenac sublingual spray
CN106580886A (zh) * 2016-12-05 2017-04-26 北京万全德众医药生物技术有限公司 一种双氯芬酸钾散剂及其制备方法
WO2019030773A1 (en) * 2017-08-10 2019-02-14 Sarudbhava Formulations Private Limited DICLOFENAC COMPOSITIONS WITH LOW DOSE
US11260026B2 (en) 2018-12-14 2022-03-01 Apr Applied Pharma Research Sa Ready to use diclofenac stick packs
KR20230022941A (ko) 2020-06-10 2023-02-16 에이피알 어플라이드 파르마 리서어치 에스.에이. 생체이용성 당-기반 디클로페낙 제형
EP3928766A1 (en) 2020-06-26 2021-12-29 Usso Barnas Pharmaceutical composition and use thereof
CN115317464B (zh) * 2022-09-01 2023-08-08 苏州弘森药业股份有限公司 一种双氯芬酸钾微胶囊及其制备方法

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JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه
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Also Published As

Publication number Publication date
EP2402003A2 (en) 2012-01-04
ES2717879T3 (es) 2019-06-26
CA2932603C (en) 2017-08-08
EP1890680B1 (en) 2017-03-08
AR057378A1 (es) 2007-11-28
EP3103441A1 (en) 2016-12-14
ZA200710858B (en) 2008-12-31
EP2402003A3 (en) 2012-05-09
MX2007016072A (es) 2008-03-10
JO3352B1 (ar) 2019-03-13
US8097651B2 (en) 2012-01-17
US9827197B2 (en) 2017-11-28
CN104856959A (zh) 2015-08-26
US20150064258A1 (en) 2015-03-05
ES2641889T3 (es) 2017-11-14
US8927604B2 (en) 2015-01-06
CN101272768A (zh) 2008-09-24
EP2402003B1 (en) 2020-05-06
NO20080352L (no) 2008-03-17
EP3103441B1 (en) 2022-03-16
ES2912897T3 (es) 2022-05-30
NO342336B1 (no) 2018-05-07
US20100204330A1 (en) 2010-08-12
AU2006257072B2 (en) 2012-08-16
HK1213814A1 (zh) 2016-07-15
CA2932603A1 (en) 2006-12-21
CA2632375A1 (en) 2006-12-21
US20170319484A1 (en) 2017-11-09
ECSP077989A (es) 2008-03-26
TR201706038T4 (tr) 2019-02-21
AU2006257072A1 (en) 2006-12-21
EP2705837A1 (en) 2014-03-12
PT1890680T (pt) 2017-05-05
KR20080024202A (ko) 2008-03-17
WO2006133954A3 (en) 2007-07-26
US20070015831A1 (en) 2007-01-18
CA2632375C (en) 2016-08-16
RU2432160C2 (ru) 2011-10-27
WO2006133954A2 (en) 2006-12-21
CN112755014A (zh) 2021-05-07
GT200600261A (es) 2007-02-05
PE20070074A1 (es) 2007-02-08
NZ564002A (en) 2011-03-31
US20130245122A1 (en) 2013-09-19
US20200323776A1 (en) 2020-10-15
BRPI0612245A2 (pt) 2010-10-26
KR101352130B1 (ko) 2014-02-06
EP1890680A2 (en) 2008-02-27
US7759394B2 (en) 2010-07-20
PL1890680T3 (pl) 2017-08-31
EP2705837B1 (en) 2019-02-20
US20090197961A1 (en) 2009-08-06
RU2008101784A (ru) 2009-07-27

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