PE20030476A1 - Composiciones farmaceuticas de acido micofenolico - Google Patents
Composiciones farmaceuticas de acido micofenolicoInfo
- Publication number
- PE20030476A1 PE20030476A1 PE2002001013A PE2002001013A PE20030476A1 PE 20030476 A1 PE20030476 A1 PE 20030476A1 PE 2002001013 A PE2002001013 A PE 2002001013A PE 2002001013 A PE2002001013 A PE 2002001013A PE 20030476 A1 PE20030476 A1 PE 20030476A1
- Authority
- PE
- Peru
- Prior art keywords
- mycophenolic acid
- refers
- tablet
- preparation
- treatment
- Prior art date
Links
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical group OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 title abstract 5
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 title abstract 4
- 229960000951 mycophenolic acid Drugs 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000654 additive Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0124953.1A GB0124953D0 (en) | 2001-10-17 | 2001-10-17 | Organic Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030476A1 true PE20030476A1 (es) | 2003-07-30 |
Family
ID=9924043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002001013A PE20030476A1 (es) | 2001-10-17 | 2002-10-15 | Composiciones farmaceuticas de acido micofenolico |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US20050013859A1 (https=) |
| EP (1) | EP1438040B2 (https=) |
| JP (2) | JP2005508959A (https=) |
| KR (1) | KR100671367B1 (https=) |
| CN (1) | CN1310640C (https=) |
| AR (2) | AR036813A1 (https=) |
| AT (1) | ATE374023T1 (https=) |
| AU (1) | AU2002338897B2 (https=) |
| BR (1) | BR0213355A (https=) |
| CA (1) | CA2460574A1 (https=) |
| CO (1) | CO5390076A1 (https=) |
| CY (1) | CY1107841T1 (https=) |
| DE (1) | DE60222687T3 (https=) |
| DK (1) | DK1438040T4 (https=) |
| EC (2) | ECSP024341A (https=) |
| ES (1) | ES2292819T5 (https=) |
| GB (1) | GB0124953D0 (https=) |
| HU (1) | HU231114B1 (https=) |
| IL (2) | IL160968A0 (https=) |
| MX (1) | MXPA04003636A (https=) |
| MY (1) | MY139206A (https=) |
| NO (1) | NO341804B1 (https=) |
| NZ (1) | NZ532280A (https=) |
| PE (1) | PE20030476A1 (https=) |
| PL (2) | PL415001A1 (https=) |
| PT (1) | PT1438040E (https=) |
| RU (2) | RU2338528C2 (https=) |
| SI (1) | SI1438040T2 (https=) |
| TW (1) | TWI333861B (https=) |
| WO (1) | WO2003032978A1 (https=) |
| ZA (1) | ZA200401977B (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0124953D0 (en) | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
| AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
| US20060069150A1 (en) * | 2004-07-20 | 2006-03-30 | Sandor Molnar | Processes for preparation of crystalline mycophenolate sodium |
| GB0419355D0 (en) * | 2004-08-31 | 2004-09-29 | Novartis Ag | Organic compounds |
| WO2006086500A2 (en) * | 2005-02-08 | 2006-08-17 | Aspreva Pharmaceuticals Sa | Compositions and methods for treating vascular, autoimmune and inflammatory diseases |
| US20060235009A1 (en) | 2005-02-08 | 2006-10-19 | Richard Glickman | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors |
| RU2008116578A (ru) * | 2005-09-30 | 2009-11-10 | Новартис АГ (CH) | Применение ингибиторов dpp-iv для лечения аутоиммунных заболеваний и отторжения трансплантата |
| US8597679B2 (en) | 2005-12-21 | 2013-12-03 | Basf Se | Fine-particle crosslinked polyvinylpyrrolidone as tablet disintegrant |
| US20090023805A1 (en) * | 2006-02-13 | 2009-01-22 | Anne Claire Marrast | Method of administration |
| CN102083410B (zh) | 2007-06-06 | 2013-04-17 | 巴斯夫欧洲公司 | 用于制备迅速崩解的片剂的药物制剂 |
| KR20160083132A (ko) | 2007-06-06 | 2016-07-11 | 바스프 에스이 | 급속 붕해 정제의 제조를 위한 제약 제제 |
| MX2010001711A (es) * | 2007-08-13 | 2010-03-11 | Panacea Biotec Ltd | Composiciones de liberacion extendida que comprenden micofenolato sodico y procedimientos de las mismas. |
| KR20100126465A (ko) * | 2008-03-05 | 2010-12-01 | 파나세아 바이오테크 리미티드 | 미코페놀레이트를 포함하는 변형 방출 제약 조성물 및 그것의 방법 |
| US20100010082A1 (en) * | 2008-07-09 | 2010-01-14 | Aspreva International Ltd. | Formulations for treating eye disorders |
| US20110086102A1 (en) * | 2009-10-13 | 2011-04-14 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
| WO2011046546A1 (en) * | 2009-10-13 | 2011-04-21 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
| WO2011051967A2 (en) * | 2009-10-23 | 2011-05-05 | Alkem Laboratories Ltd | Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof |
| GB201100786D0 (en) | 2011-01-18 | 2011-03-02 | Ems Sa | Pharmaceutical compositions of immunosuppressants |
| CN102793658A (zh) * | 2012-08-23 | 2012-11-28 | 无锡福祈制药有限公司 | 一种含有麦考酚酸或麦考酚酸盐的骨架型制剂及其包衣片 |
| CN103845323B (zh) * | 2012-11-30 | 2018-02-02 | 重庆华邦制药有限公司 | 麦考酚酸及其盐肠溶制剂和制备方法 |
| WO2014167442A1 (en) | 2013-03-26 | 2014-10-16 | Wockhardt Limited | Pharmaceutical compositions comprising mycophenolic acid or salts thereof |
| CN106727403A (zh) * | 2017-01-03 | 2017-05-31 | 无锡福祈制药有限公司 | 一种麦考酚钠肠溶片及其制备方法 |
| WO2018170022A2 (en) * | 2017-03-13 | 2018-09-20 | Okava Pharmaceuticals, Inc. | Methods and compositions for delivering mycophenolic acid active agents to non-human mammals |
| CA3102412A1 (en) | 2018-06-06 | 2019-12-12 | Metavant Sciences Gmbh | Methods of treating subjects having diabetes with chronic kidney disease |
| AU2019286326A1 (en) * | 2018-06-14 | 2020-12-10 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
| RU2723255C2 (ru) * | 2018-11-14 | 2020-06-09 | Общество с ограниченной ответственностью "Изварино Фарма" | Экструдат с микофенолятом натрия для получения пероральной твердой лекарственной формы |
| US12569481B2 (en) | 2020-06-12 | 2026-03-10 | Vanderbilt University | Methods of treatment for gastrointestinal motility disorders |
| EP4248958A3 (en) * | 2021-01-28 | 2024-01-03 | Priothera SAS | Methods of treatment with s1p receptor modulators |
| AU2021424131A1 (en) * | 2021-01-28 | 2023-07-27 | Priothera Limited | Methods of treatment with s1p receptor modulators |
| EP4346790A4 (en) * | 2021-05-26 | 2025-04-16 | The Texas A&M University System | Biodegradable mucoadhesive pharmaceutical formulations and methods thereof |
| CN117442580B (zh) * | 2023-12-21 | 2024-04-05 | 泊诺(天津)创新医药研究有限公司 | 一种高生物利用度麦考酚钠肠溶片及其制备方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1157100A (en) † | 1966-09-27 | 1969-07-02 | Ici Ltd | Pharmaceutical Compositions |
| GB1157099A (en) * | 1966-09-27 | 1969-07-02 | Ici Ltd | Fermentation Process |
| GB1203328A (en) * | 1968-06-04 | 1970-08-26 | Ici Ltd | Pharmaceutical compositions |
| US3705946A (en) * | 1971-05-25 | 1972-12-12 | Lilly Co Eli | Method of treating hyperuricemia |
| US3880995A (en) * | 1973-05-14 | 1975-04-29 | Lilly Co Eli | Treatment of arthritis with mycophenolic acid and derivatives |
| JPS56127093A (en) * | 1980-03-10 | 1981-10-05 | Ajinomoto Co Inc | Preparation of mycophenolic acid |
| US4959387A (en) * | 1986-01-23 | 1990-09-25 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
| US4725622A (en) * | 1986-01-23 | 1988-02-16 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
| US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
| US4748173A (en) * | 1987-01-30 | 1988-05-31 | Syntex (U.S.A.) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions |
| US5177072A (en) * | 1987-01-30 | 1993-01-05 | Syntex (U.S.A.) Inc. | Treatment of autoimmune inflammatory, and psoriatic diseases with heterocyclic aminoalkyl esters of mycophenolic acid and derivatives |
| EP0670724A1 (en) * | 1992-11-24 | 1995-09-13 | Syntex (U.S.A.) Inc. | Use of mycophenolic acid, mycophenolate mofetil or derivate thereof to inhibit stenosis |
| WO1994012184A1 (en) * | 1992-11-24 | 1994-06-09 | Syntex (U.S.A.) Inc. | Use of mycophenolic acid, mycophenolate mofetil or derivate thereof to inhibit stenosis |
| US5656290A (en) * | 1993-02-26 | 1997-08-12 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
| US5843479A (en) * | 1993-02-26 | 1998-12-01 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
| US5651983A (en) * | 1993-02-26 | 1997-07-29 | The Procter & Gamble Company | Bisacodyl dosage form for colonic delivery |
| CA2156726C (en) * | 1993-02-26 | 2000-10-17 | Paula Denise Davis | Bisacodyl dosage form |
| US5455045A (en) * | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
| CZ301771B6 (cs) * | 1993-10-01 | 2010-06-16 | Syntex (U.S.A.) Llc. | Farmaceutický prostredek ve forme suchého granulátu obsahující mofetil mykofenolát nebo kyselinu mykofenolovou a zpusob jeho prípravy |
| US5514663A (en) * | 1993-10-19 | 1996-05-07 | The Procter & Gamble Company | Senna dosage form |
| EP0724441A1 (en) * | 1993-10-19 | 1996-08-07 | The Procter & Gamble Company | Picosulphate dosage form |
| US5482718A (en) * | 1994-03-23 | 1996-01-09 | Hoffmann-La Roche Inc. | Colon-targeted delivery system |
| US5686106A (en) * | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
| ID18663A (id) * | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
| JP2002544167A (ja) * | 1999-05-10 | 2002-12-24 | ノバルティス アクチエンゲゼルシャフト | 有機化合物 |
| HUP9903226A2 (en) * | 1999-09-23 | 2002-08-28 | Gyogyszerki | Process for producing mycophenolic acid and derivatives thereof |
| WO2001064931A1 (en) * | 2000-02-29 | 2001-09-07 | Biocon India Limited | Manufacture and purification of mycophenolic acid |
| GB0124953D0 (en) | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
| GB0301259D0 (en) | 2003-01-20 | 2003-02-19 | Novartis Ag | Organic compounds |
-
2001
- 2001-10-17 GB GBGB0124953.1A patent/GB0124953D0/en not_active Ceased
-
2002
- 2002-10-15 CO CO02092380A patent/CO5390076A1/es not_active Application Discontinuation
- 2002-10-15 TW TW091123694A patent/TWI333861B/zh not_active IP Right Cessation
- 2002-10-15 AR ARP020103852A patent/AR036813A1/es not_active Application Discontinuation
- 2002-10-15 PE PE2002001013A patent/PE20030476A1/es not_active Application Discontinuation
- 2002-10-16 DE DE60222687.2T patent/DE60222687T3/de not_active Expired - Lifetime
- 2002-10-16 DK DK02777314.2T patent/DK1438040T4/da active
- 2002-10-16 IL IL16096802A patent/IL160968A0/xx unknown
- 2002-10-16 JP JP2003535782A patent/JP2005508959A/ja active Pending
- 2002-10-16 SI SI200230646T patent/SI1438040T2/sl unknown
- 2002-10-16 KR KR1020047005588A patent/KR100671367B1/ko not_active Ceased
- 2002-10-16 CA CA002460574A patent/CA2460574A1/en not_active Abandoned
- 2002-10-16 WO PCT/EP2002/011589 patent/WO2003032978A1/en not_active Ceased
- 2002-10-16 CN CNB028198611A patent/CN1310640C/zh not_active Expired - Fee Related
- 2002-10-16 HU HU0600451A patent/HU231114B1/hu unknown
- 2002-10-16 US US10/492,289 patent/US20050013859A1/en not_active Abandoned
- 2002-10-16 MY MYPI20023865A patent/MY139206A/en unknown
- 2002-10-16 AU AU2002338897A patent/AU2002338897B2/en not_active Expired
- 2002-10-16 PT PT02777314T patent/PT1438040E/pt unknown
- 2002-10-16 PL PL415001A patent/PL415001A1/pl unknown
- 2002-10-16 NZ NZ532280A patent/NZ532280A/en not_active IP Right Cessation
- 2002-10-16 BR BRPI0213355-5A patent/BR0213355A/pt active Search and Examination
- 2002-10-16 RU RU2004115332/15A patent/RU2338528C2/ru not_active IP Right Cessation
- 2002-10-16 PL PL367738A patent/PL234541B1/pl unknown
- 2002-10-16 AT AT02777314T patent/ATE374023T1/de active
- 2002-10-16 ES ES02777314T patent/ES2292819T5/es not_active Expired - Lifetime
- 2002-10-16 MX MXPA04003636A patent/MXPA04003636A/es active IP Right Grant
- 2002-10-16 EP EP02777314.2A patent/EP1438040B2/en not_active Expired - Lifetime
- 2002-11-19 EC EC2002004341A patent/ECSP024341A/es unknown
- 2002-11-19 EC EC2002004342A patent/ECSP024342A/es unknown
-
2004
- 2004-03-11 ZA ZA200401977A patent/ZA200401977B/en unknown
- 2004-03-18 IL IL160968A patent/IL160968A/en active IP Right Grant
- 2004-05-03 NO NO20041785A patent/NO341804B1/no not_active IP Right Cessation
-
2007
- 2007-08-13 RU RU2007130786/15A patent/RU2381026C2/ru not_active IP Right Cessation
- 2007-12-19 CY CY20071101618T patent/CY1107841T1/el unknown
-
2009
- 2009-01-23 JP JP2009012781A patent/JP2009137996A/ja active Pending
-
2010
- 2010-05-03 US US12/772,608 patent/US20100210717A1/en not_active Abandoned
-
2012
- 2012-05-04 AR ARP120101574A patent/AR085778A2/es not_active Application Discontinuation
- 2012-05-29 US US13/482,003 patent/US20120237601A1/en not_active Abandoned
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