KR100671367B1 - 미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물 - Google Patents

미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물 Download PDF

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Publication number
KR100671367B1
KR100671367B1 KR1020047005588A KR20047005588A KR100671367B1 KR 100671367 B1 KR100671367 B1 KR 100671367B1 KR 1020047005588 A KR1020047005588 A KR 1020047005588A KR 20047005588 A KR20047005588 A KR 20047005588A KR 100671367 B1 KR100671367 B1 KR 100671367B1
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KR
South Korea
Prior art keywords
solid dosage
mycophenolate
mycophenolic acid
tablets
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020047005588A
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English (en)
Korean (ko)
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KR20050037409A (ko
Inventor
위르겐 데데릭스
토마스 리가시
Original Assignee
노파르티스 아게
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Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20050037409A publication Critical patent/KR20050037409A/ko
Application granted granted Critical
Publication of KR100671367B1 publication Critical patent/KR100671367B1/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020047005588A 2001-10-17 2002-10-16 미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물 Ceased KR100671367B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0124953.1 2001-10-17
GBGB0124953.1A GB0124953D0 (en) 2001-10-17 2001-10-17 Organic Compounds

Publications (2)

Publication Number Publication Date
KR20050037409A KR20050037409A (ko) 2005-04-21
KR100671367B1 true KR100671367B1 (ko) 2007-01-19

Family

ID=9924043

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047005588A Ceased KR100671367B1 (ko) 2001-10-17 2002-10-16 미코페놀산 또는 미코페놀레이트 염을 포함하는 제약조성물

Country Status (31)

Country Link
US (3) US20050013859A1 (https=)
EP (1) EP1438040B2 (https=)
JP (2) JP2005508959A (https=)
KR (1) KR100671367B1 (https=)
CN (1) CN1310640C (https=)
AR (2) AR036813A1 (https=)
AT (1) ATE374023T1 (https=)
AU (1) AU2002338897B2 (https=)
BR (1) BR0213355A (https=)
CA (1) CA2460574A1 (https=)
CO (1) CO5390076A1 (https=)
CY (1) CY1107841T1 (https=)
DE (1) DE60222687T3 (https=)
DK (1) DK1438040T4 (https=)
EC (2) ECSP024341A (https=)
ES (1) ES2292819T5 (https=)
GB (1) GB0124953D0 (https=)
HU (1) HU231114B1 (https=)
IL (2) IL160968A0 (https=)
MX (1) MXPA04003636A (https=)
MY (1) MY139206A (https=)
NO (1) NO341804B1 (https=)
NZ (1) NZ532280A (https=)
PE (1) PE20030476A1 (https=)
PL (2) PL415001A1 (https=)
PT (1) PT1438040E (https=)
RU (2) RU2338528C2 (https=)
SI (1) SI1438040T2 (https=)
TW (1) TWI333861B (https=)
WO (1) WO2003032978A1 (https=)
ZA (1) ZA200401977B (https=)

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WO2006086500A2 (en) * 2005-02-08 2006-08-17 Aspreva Pharmaceuticals Sa Compositions and methods for treating vascular, autoimmune and inflammatory diseases
US20060235009A1 (en) 2005-02-08 2006-10-19 Richard Glickman Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors
RU2008116578A (ru) * 2005-09-30 2009-11-10 Новартис АГ (CH) Применение ингибиторов dpp-iv для лечения аутоиммунных заболеваний и отторжения трансплантата
US8597679B2 (en) 2005-12-21 2013-12-03 Basf Se Fine-particle crosslinked polyvinylpyrrolidone as tablet disintegrant
US20090023805A1 (en) * 2006-02-13 2009-01-22 Anne Claire Marrast Method of administration
CN102083410B (zh) 2007-06-06 2013-04-17 巴斯夫欧洲公司 用于制备迅速崩解的片剂的药物制剂
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US20110086102A1 (en) * 2009-10-13 2011-04-14 Teva Pharmaceutical Industries Ltd. Delayed release compositions
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CN103845323B (zh) * 2012-11-30 2018-02-02 重庆华邦制药有限公司 麦考酚酸及其盐肠溶制剂和制备方法
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CN106727403A (zh) * 2017-01-03 2017-05-31 无锡福祈制药有限公司 一种麦考酚钠肠溶片及其制备方法
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AU2019286326A1 (en) * 2018-06-14 2020-12-10 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
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US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
EP4248958A3 (en) * 2021-01-28 2024-01-03 Priothera SAS Methods of treatment with s1p receptor modulators
AU2021424131A1 (en) * 2021-01-28 2023-07-27 Priothera Limited Methods of treatment with s1p receptor modulators
EP4346790A4 (en) * 2021-05-26 2025-04-16 The Texas A&M University System Biodegradable mucoadhesive pharmaceutical formulations and methods thereof
CN117442580B (zh) * 2023-12-21 2024-04-05 泊诺(天津)创新医药研究有限公司 一种高生物利用度麦考酚钠肠溶片及其制备方法

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Also Published As

Publication number Publication date
MXPA04003636A (es) 2004-07-27
NO20041785L (no) 2004-05-03
TWI333861B (en) 2010-12-01
RU2007130786A (ru) 2009-02-20
ATE374023T1 (de) 2007-10-15
US20100210717A1 (en) 2010-08-19
DK1438040T4 (da) 2020-01-27
CN1564684A (zh) 2005-01-12
EP1438040A1 (en) 2004-07-21
GB0124953D0 (en) 2001-12-05
RU2338528C2 (ru) 2008-11-20
ZA200401977B (en) 2006-05-31
CY1107841T1 (el) 2013-06-19
DK1438040T3 (da) 2008-02-04
AR036813A1 (es) 2004-10-06
CN1310640C (zh) 2007-04-18
HK1067861A1 (en) 2005-04-22
RU2381026C2 (ru) 2010-02-10
SI1438040T2 (sl) 2020-02-28
BR0213355A (pt) 2006-05-23
PL234541B1 (pl) 2020-03-31
AU2002338897B2 (en) 2006-10-19
ES2292819T3 (es) 2008-03-16
ECSP024341A (es) 2003-12-01
DE60222687T2 (de) 2008-07-17
ECSP024342A (es) 2003-03-10
MY139206A (en) 2009-08-28
HUP0600451A2 (en) 2006-09-28
IL160968A (en) 2016-04-21
PT1438040E (pt) 2008-01-02
PL415001A1 (pl) 2016-02-29
JP2005508959A (ja) 2005-04-07
IL160968A0 (en) 2004-08-31
PL367738A1 (en) 2005-03-07
US20050013859A1 (en) 2005-01-20
NZ532280A (en) 2007-05-31
DE60222687T3 (de) 2020-03-05
DE60222687D1 (de) 2007-11-08
KR20050037409A (ko) 2005-04-21
ES2292819T5 (es) 2020-05-29
RU2004115332A (ru) 2005-04-20
NO341804B1 (no) 2018-01-22
EP1438040B1 (en) 2007-09-26
US20120237601A1 (en) 2012-09-20
SI1438040T1 (sl) 2008-04-30
CO5390076A1 (es) 2004-04-30
PE20030476A1 (es) 2003-07-30
WO2003032978A1 (en) 2003-04-24
AR085778A2 (es) 2013-10-30
JP2009137996A (ja) 2009-06-25
HU231114B1 (hu) 2020-09-28
CA2460574A1 (en) 2003-04-24
EP1438040B2 (en) 2019-10-16

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Comment text: Trial Decision on Invalidation (Patent, Utility Model, Industrial Design)

Patent event code: PJ20011S05I

Appeal kind category: Invalidation

Decision date: 20171222

Appeal identifier: 2017200001175

Request date: 20170217

FPAY Annual fee payment

Payment date: 20180103

Year of fee payment: 12

PR1001 Payment of annual fee

Payment date: 20180103

Start annual number: 12

End annual number: 12

J2X2 Appeal (before the supreme court)

Free format text: TRIAL NUMBER: 2018300010282; APPEAL BEFORE THE SUPREME COURT FOR INVALIDATION

PJ2002 Appeal before the supreme court

Comment text: Trial Decision on Invalidation (Patent, Utility Model, Industrial Design)

Patent event date: 20170119

Patent event code: PJ20021S05I

Request date: 20180131

Appeal identifier: 2018300010282

Appeal kind category: Invalidation

Decision date: 20191031

FPAY Annual fee payment

Payment date: 20190103

Year of fee payment: 13

PR1001 Payment of annual fee

Payment date: 20190103

Start annual number: 13

End annual number: 13

J302 Written judgement (patent court)

Free format text: TRIAL NUMBER: 2017200001175; JUDGMENT (PATENT COURT) FOR INVALIDATION REQUESTED 20170217

Effective date: 20171222

J303 Written judgement (supreme court)

Free format text: TRIAL NUMBER: 2018300010282; JUDGMENT (SUPREME COURT) FOR INVALIDATION REQUESTED 20180131

Effective date: 20191031

PJ1302 Judgment (patent court)

Patent event date: 20191108

Comment text: Written Judgment (Patent Court)

Patent event code: PJ13021S01D

Request date: 20170217

Decision date: 20171222

Appeal identifier: 2017200001175

Appeal kind category: Invalidation

PJ1303 Judgment (supreme court)

Comment text: Written Judgment (Supreme Court)

Patent event date: 20191108

Patent event code: PJ13031S01D

Decision date: 20191031

Appeal kind category: Invalidation

Request date: 20180131

Appeal identifier: 2018300010282

PJ2201 Remand (intellectual property tribunal)

Patent event code: PJ22012S01I

Comment text: Written Judgment (Patent Court)

Patent event date: 20191108

Request date: 20191108

Appeal kind category: Invalidation

Appeal identifier: 2019130000159

Decision date: 20191121

J301 Trial decision

Free format text: TRIAL NUMBER: 2019130000159; TRIAL DECISION FOR INVALIDATION REQUESTED 20191108

Effective date: 20191121

PJ1301 Trial decision

Patent event code: PJ13011S09D

Patent event date: 20191121

Comment text: Trial Decision on Final Judgment on Revocation

Appeal kind category: Invalidation

Request date: 20191108

Decision date: 20191121

Appeal identifier: 2019130000159

FPAY Annual fee payment

Payment date: 20200103

Year of fee payment: 14

PR1001 Payment of annual fee

Payment date: 20200103

Start annual number: 14

End annual number: 14

PC2102 Extinguishment

Termination category: Others

Termination date: 20200304

G170 Re-publication after modification of scope of protection [patent]
PG1701 Publication of correction

Publication date: 20200312