PE20030289A1 - Hidrolizado de proteinas de suero bioactivo mejorado - Google Patents
Hidrolizado de proteinas de suero bioactivo mejoradoInfo
- Publication number
- PE20030289A1 PE20030289A1 PE2001000942A PE2001000942A PE20030289A1 PE 20030289 A1 PE20030289 A1 PE 20030289A1 PE 2001000942 A PE2001000942 A PE 2001000942A PE 2001000942 A PE2001000942 A PE 2001000942A PE 20030289 A1 PE20030289 A1 PE 20030289A1
- Authority
- PE
- Peru
- Prior art keywords
- protease
- whey protein
- hydrolysis
- enzyme
- hydrolyzed
- Prior art date
Links
- 108010046377 Whey Proteins Proteins 0.000 title abstract 4
- 235000021119 whey protein Nutrition 0.000 title abstract 4
- 230000000975 bioactive effect Effects 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 6
- 108090000790 Enzymes Proteins 0.000 abstract 6
- 108091005804 Peptidases Proteins 0.000 abstract 5
- 239000004365 Protease Substances 0.000 abstract 4
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 4
- 230000007062 hydrolysis Effects 0.000 abstract 4
- 238000006460 hydrolysis reaction Methods 0.000 abstract 4
- 235000019419 proteases Nutrition 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108091005508 Acid proteases Proteins 0.000 abstract 1
- 108090000145 Bacillolysin Proteins 0.000 abstract 1
- 108091005658 Basic proteases Proteins 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 108091005507 Neutral proteases Proteins 0.000 abstract 1
- 102000035092 Neutral proteases Human genes 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- -1 VALIDASE Proteins 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 108010009355 microbial metalloproteinases Proteins 0.000 abstract 1
- 235000019833 protease Nutrition 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Dairy Products (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
SE REFIERE A UN PROCESO PARA PREPARAR UN HIDROLIZADO DE PROTEINA DE SUERO MEJORADO QUE CONTIENE PEPTIDOS BIOACTIVOS QUE COMPRENDEN UN AISLADO DE PROTEINA DE SUERO CON UNA O MAS ENZIMAS CARACTERIZADO: i) LA ENZIMA ES UNA PROTEASA LABIL AL CALOR; ii) SE CONDUCE LA HIDROLISIS A UNA TEMPERATURA ENTRE 30°C Y 65°C A UN pH DE 3.5 A 9.0 CUANDO ES UNA PROTEASA NEUTRA, A UN pH DE 2.5 A 6.0 CUANDO LA ENZIMA ES UNA PROTEASA ACIDA Y A UN pH 5.0 A 10.0 CUANDO LA ENZIMA ES UNA PROTEASA ALCALINA; iii) LA HIDROLISIS SE TERMINA CUANDO SE ALCANZA UN GRADO DE HIDROLISI Y NO MAYOR DE UN 10%; iv) SE TERMINA LA HIDROLISIS AL DESACTIVAR UNA O MAS ENZIMAS; v) LAS CONDICIONES PARA EL PASO iv) SON SUFICIENTEMENTE LIGERAS PARA EVITAR MANIFIESTA DESNATURALIZACION DE PEPTIDOS O PROTEINAS RESIDUALES EN DICHO HIDROLIZADO. LA ENZIMA SE SELECCIONA DE PROTEASA P6, PROTEASA A, PROTEASA M, PEPTIDASA, NEUTRASE, VALIDASE, AFP 2000. EL HIDROLIZADO DE PROTEINA DE SUERO COMPRENDE UNO O MAS PEPTIDOS BIOACTIVOS SELECCIONADOS DE SAP [SEQ ID NO: 1] , MKG [SEQ ID NO:2], ALPMH [SEQ ID N0:3], ENTRE OTROS. LA ADMINISTRACION DE UN HIDROLIZADO WPI ES UTIL PARA EL TRATAMIENTO DE HIPERTENSION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ506866A NZ506866A (en) | 2000-09-11 | 2000-09-11 | Bioactive whey protein hydrolysate free of bitter flavours wherein the enzyme used is a heat labile protease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030289A1 true PE20030289A1 (es) | 2003-03-25 |
Family
ID=19928101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000942A PE20030289A1 (es) | 2000-09-11 | 2001-09-20 | Hidrolizado de proteinas de suero bioactivo mejorado |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1317186B1 (es) |
| JP (1) | JP2004508025A (es) |
| KR (1) | KR100845362B1 (es) |
| CN (1) | CN1229031C (es) |
| AT (1) | ATE494795T1 (es) |
| AU (2) | AU2001290376B2 (es) |
| BR (1) | BR0113812A (es) |
| CA (1) | CA2421714A1 (es) |
| DE (1) | DE60143846D1 (es) |
| DK (1) | DK1317186T3 (es) |
| ES (1) | ES2359789T3 (es) |
| HK (1) | HK1063132A1 (es) |
| HU (1) | HUP0302370A2 (es) |
| MX (1) | MXPA03002109A (es) |
| NO (1) | NO326072B1 (es) |
| NZ (1) | NZ506866A (es) |
| PE (1) | PE20030289A1 (es) |
| WO (1) | WO2002019837A1 (es) |
| ZA (1) | ZA200301982B (es) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004021797A1 (en) | 2002-07-29 | 2004-03-18 | Aminotech As | Method for production of peptides/amino acids produced by said method and use of the same |
| TWI317636B (en) * | 2002-11-22 | 2009-12-01 | Meiji Dairies Corp | Nutritional compositions for liver disease patients or for patients underhigh levels of invasive stress |
| US7399496B2 (en) * | 2003-02-07 | 2008-07-15 | Glanbia Nutritionals (Ireland) Limited | Hydrolyzed whey protein compositions |
| EP1568707A1 (en) * | 2004-02-26 | 2005-08-31 | Puleva Biotech, S.A. | Antihypertensive peptides from casein hydrolysates |
| CN100415768C (zh) * | 2004-11-29 | 2008-09-03 | 中国农业大学 | 乳清蛋白酶法生产血管紧张素转化酶（ace）抑制肽的方法 |
| US20100056458A1 (en) * | 2005-06-30 | 2010-03-04 | Campina Nederland Holding B.V. | Peptides Inhibiting Angiotensin-Converting Enzyme |
| EP1998637A1 (en) * | 2006-03-24 | 2008-12-10 | Unilever N.V. | Healthy food product |
| JP5306188B2 (ja) * | 2006-06-15 | 2013-10-02 | マレー・ゴールバーン・コー−オペラティヴ・カンパニー・リミテッド | 筋肉回復を高めるための乳清タンパク質および加水分解物を含む調製物 |
| EP1967524A1 (en) * | 2007-03-06 | 2008-09-10 | Friesland Brands B.V. | Methods for producing ACE-inhibitory peptides from whey and peptides obtained thereby |
| US20090196973A1 (en) * | 2008-02-01 | 2009-08-06 | Rich Products Corporation | Foam Compositions |
| DE102008032828A1 (de) * | 2008-07-02 | 2010-01-07 | Technische Universität Dresden | Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel |
| US9055752B2 (en) | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
| CN101736067B (zh) * | 2010-01-08 | 2012-04-18 | 中国农业大学 | 一种乳清蛋白降血压肽及其制备方法与应用 |
| CN101829316B (zh) * | 2010-04-30 | 2012-07-11 | 中国人民解放军总医院 | 一种乳清蛋白水解物及其在制备降糖药物中的用途 |
| UA112972C2 (uk) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | Рідкий молочний концентрат з високим вмістом сухих речовин |
| WO2012075570A1 (en) * | 2010-12-09 | 2012-06-14 | Mcgill University | Bioactive peptides and proteins containing bioactive peptides, their uses and processes for making the same |
| JP5892687B2 (ja) | 2011-07-07 | 2016-03-23 | 高砂香料工業株式会社 | 風味改善ペプチド |
| CN103695518B (zh) * | 2013-12-30 | 2016-04-06 | 东北农业大学 | 利用乳清蛋白肽降低血清胆固醇水平的产品和制备方法 |
| US10639334B2 (en) * | 2014-01-07 | 2020-05-05 | Mead Johnson Nutrition Company | Pediatric nutritional composition with milk peptides for healthy growth and development |
| CN103805664B (zh) * | 2014-03-06 | 2017-04-05 | 渤海大学 | 一种低敏性糖基化乳清蛋白水解物及其制备方法 |
| WO2015169928A1 (en) * | 2014-05-07 | 2015-11-12 | Nestec S.A. | Foamable dairy product |
| JP6022738B2 (ja) * | 2014-06-16 | 2016-11-09 | キリン株式会社 | 記憶学習機能及び／又は認知機能を増強するための組成物 |
| JP6262694B2 (ja) * | 2014-08-18 | 2018-01-17 | 森永乳業株式会社 | プロリルオリゴペプチダーゼ阻害剤 |
| WO2016174651A2 (en) | 2015-10-01 | 2016-11-03 | Frieslandcampina Nederland B.V. | Liquid nutritional composition comprising micellar casein and hydrolysed whey protein |
| JPWO2017086303A1 (ja) * | 2015-11-16 | 2018-09-20 | キリン株式会社 | ペプチド組成物およびその製造方法 |
| BR112018010672B1 (pt) | 2015-12-18 | 2022-05-10 | Société des Produits Nestlé S.A. | Composições líquidas esterilizadas por calor com alto teor de proteína, seu processo contínuo de preparação, uso de proteína hidrolisada, e método para controlar a viscosidade e evitar o gosto amargo das ditas composições |
| CN107136295B (zh) * | 2016-03-01 | 2021-07-27 | 内蒙古伊利实业集团股份有限公司 | 一种部分水解乳清蛋白粉及其制备方法 |
| CN107814836A (zh) * | 2017-12-01 | 2018-03-20 | 浙江熊猫乳业集团股份有限公司 | 一种生物活性多肽fpgpipns及其制备方法和应用 |
| CN107858394B (zh) * | 2017-12-25 | 2021-09-07 | 内蒙古蒙牛乳业（集团）股份有限公司 | 乳清蛋白水解产物的制备方法 |
| JP2022534723A (ja) | 2019-05-29 | 2022-08-03 | アーラ フーズ エエムビエ | 味が良い（Ｐａｌａｔａｂｌｅ）高度に加水分解されたホエイタンパク質加水分解物 |
| CN113061175B (zh) * | 2020-12-17 | 2023-04-21 | 西北民族大学 | 以曲拉为原料制备的钙共沉淀蛋白及其制备方法 |
| CN115669945B (zh) * | 2022-10-24 | 2024-03-08 | 上海艾斯顿医疗科技有限公司 | 一种具有神经营养作用的脂质体包裹多肽及制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK589785A (da) * | 1985-12-18 | 1987-06-19 | Samuelsson Ernst Gunnar | Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet |
| SE459140B (sv) * | 1986-11-25 | 1989-06-12 | Albuglobe Ab | Hydrolys av vassleprotein foer att underlaetta avskiljning av fett daerifraan |
| WO1991013554A1 (en) * | 1990-03-09 | 1991-09-19 | Novo Nordisk A/S | Protein hydrolysates |
| DE69216231T2 (de) * | 1991-05-31 | 1997-06-12 | Danmark Protein As | Verfahren zur herstellung eines molkeprotein-hydrolysates |
| AU2468292A (en) * | 1991-08-30 | 1993-04-05 | Teagasc, The Agriculture And Food Development Authority | Hypoallergenic whey protein hydrolysate |
| DK71292D0 (es) * | 1992-05-27 | 1992-05-27 | Novo Nordisk As | |
| JP3059595B2 (ja) * | 1992-11-20 | 2000-07-04 | 森永乳業株式会社 | 沈澱を生じない乳清蛋白質分解物の製造法 |
| AU692612B2 (en) * | 1994-10-14 | 1998-06-11 | Morinaga Milk Industry Company Limited | Peptide mixture and products thereof |
| JPH11509727A (ja) * | 1995-06-30 | 1999-08-31 | エムディ フーズ エイ．エム．ビィ．エイ． | ペプチド混合物の製法 |
| JPH1033115A (ja) * | 1996-07-24 | 1998-02-10 | Nouchikusangiyou Shinko Jigyodan | ホエー飲料とその製造法 |
| AU761477B2 (en) * | 1998-06-17 | 2003-06-05 | New Zealand Dairy Board | Bioactive whey protein hydrolysate |
| MY129566A (en) * | 1999-01-19 | 2007-04-30 | Nestle Sa | A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance |
-
2000
- 2000-09-11 NZ NZ506866A patent/NZ506866A/en unknown
-
2001
- 2001-09-11 AT AT01970375T patent/ATE494795T1/de not_active IP Right Cessation
- 2001-09-11 AU AU2001290376A patent/AU2001290376B2/en not_active Ceased
- 2001-09-11 WO PCT/NZ2001/000188 patent/WO2002019837A1/en active IP Right Grant
- 2001-09-11 ES ES01970375T patent/ES2359789T3/es not_active Expired - Lifetime
- 2001-09-11 AU AU9037601A patent/AU9037601A/xx active Pending
- 2001-09-11 EP EP01970375A patent/EP1317186B1/en not_active Expired - Lifetime
- 2001-09-11 MX MXPA03002109A patent/MXPA03002109A/es not_active Application Discontinuation
- 2001-09-11 CA CA002421714A patent/CA2421714A1/en not_active Abandoned
- 2001-09-11 KR KR1020037003596A patent/KR100845362B1/ko not_active IP Right Cessation
- 2001-09-11 DK DK01970375.0T patent/DK1317186T3/da active
- 2001-09-11 CN CNB018187250A patent/CN1229031C/zh not_active Expired - Fee Related
- 2001-09-11 HU HU0302370A patent/HUP0302370A2/hu unknown
- 2001-09-11 JP JP2002524329A patent/JP2004508025A/ja active Pending
- 2001-09-11 DE DE60143846T patent/DE60143846D1/de not_active Expired - Lifetime
- 2001-09-11 BR BR0113812-0A patent/BR0113812A/pt not_active IP Right Cessation
- 2001-09-20 PE PE2001000942A patent/PE20030289A1/es not_active Application Discontinuation
-
2003
- 2003-03-10 NO NO20031096A patent/NO326072B1/no not_active IP Right Cessation
- 2003-03-11 ZA ZA200301982A patent/ZA200301982B/en unknown
-
2004
- 2004-08-09 HK HK04105950A patent/HK1063132A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE494795T1 (de) | 2011-01-15 |
| EP1317186B1 (en) | 2011-01-12 |
| EP1317186A4 (en) | 2006-04-19 |
| CA2421714A1 (en) | 2002-03-14 |
| CN1474656A (zh) | 2004-02-11 |
| MXPA03002109A (es) | 2004-05-24 |
| JP2004508025A (ja) | 2004-03-18 |
| KR20030046442A (ko) | 2003-06-12 |
| ZA200301982B (en) | 2004-06-25 |
| DE60143846D1 (de) | 2011-02-24 |
| HUP0302370A2 (hu) | 2003-10-28 |
| HK1063132A1 (en) | 2004-12-17 |
| WO2002019837A1 (en) | 2002-03-14 |
| AU9037601A (en) | 2002-03-22 |
| CN1229031C (zh) | 2005-11-30 |
| DK1317186T3 (da) | 2011-05-02 |
| NO326072B1 (no) | 2008-09-15 |
| AU2001290376B2 (en) | 2005-08-25 |
| ES2359789T3 (es) | 2011-05-26 |
| NO20031096L (no) | 2003-05-07 |
| NZ506866A (en) | 2003-05-30 |
| BR0113812A (pt) | 2005-02-01 |
| EP1317186A1 (en) | 2003-06-11 |
| NO20031096D0 (no) | 2003-03-10 |
| KR100845362B1 (ko) | 2008-07-09 |
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