PA8570001A1 - Aminoacidos con afinidad por la proteina a2 delta - Google Patents

Aminoacidos con afinidad por la proteina a2 delta

Info

Publication number
PA8570001A1
PA8570001A1 PA20038570001A PA8570001A PA8570001A1 PA 8570001 A1 PA8570001 A1 PA 8570001A1 PA 20038570001 A PA20038570001 A PA 20038570001A PA 8570001 A PA8570001 A PA 8570001A PA 8570001 A1 PA8570001 A1 PA 8570001A1
Authority
PA
Panama
Prior art keywords
delta
amino acids
affinity
protein
subunity
Prior art date
Application number
PA20038570001A
Other languages
English (en)
Inventor
David Juergen Wustrow
Nancy Sue Barta
Jacob Bradley Schwartz
Andrew John Thorpe
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28675482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8570001(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PA8570001A1 publication Critical patent/PA8570001A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

ESTA INVENCION SE REFIERE A CIERTOS B-AMINOACIDOS QUE SE UNEN A LA SUBUNIDAD ALFA-2-DELTA (A2O) DE UN CANAL DE CALCIO. ESTOS COMPUESTOS Y SUS SALES FARMACEUTICAMENTE ACEPTABLES SON UTILES EN EL TRATAMIENTO DE UNA VARIEDAD DE TRASTORNOS PSIQUIATRICOS, DEL DOLOR Y OTROS.
PA20038570001A 2002-03-28 2003-03-28 Aminoacidos con afinidad por la proteina a2 delta PA8570001A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36841302P 2002-03-28 2002-03-28

Publications (1)

Publication Number Publication Date
PA8570001A1 true PA8570001A1 (es) 2003-12-10

Family

ID=28675482

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20038570001A PA8570001A1 (es) 2002-03-28 2003-03-28 Aminoacidos con afinidad por la proteina a2 delta

Country Status (43)

Country Link
US (3) US7064147B2 (es)
EP (2) EP1492761B1 (es)
JP (2) JP3831379B2 (es)
KR (2) KR100694719B1 (es)
CN (2) CN100462351C (es)
AP (1) AP1791A (es)
AR (2) AR039154A1 (es)
AU (1) AU2003208538B2 (es)
BR (1) BR0308814A (es)
CA (1) CA2480872C (es)
CR (1) CR7501A (es)
CU (1) CU23331B7 (es)
CY (1) CY1109304T1 (es)
DE (1) DE60328469D1 (es)
DK (1) DK1492761T3 (es)
EA (2) EA008709B1 (es)
EC (1) ECSP045319A (es)
ES (1) ES2327910T3 (es)
GE (2) GEP20084298B (es)
GT (2) GT200300072A (es)
HK (1) HK1076627A1 (es)
HR (2) HRP20040891A2 (es)
IL (2) IL164110A0 (es)
IS (2) IS7451A (es)
MA (1) MA27188A1 (es)
MX (1) MXPA04009373A (es)
MY (1) MY131424A (es)
NI (1) NI200300043A (es)
NO (2) NO20044614L (es)
NZ (2) NZ535364A (es)
OA (1) OA12795A (es)
PA (1) PA8570001A1 (es)
PE (1) PE20040349A1 (es)
PL (1) PL209750B1 (es)
PT (1) PT1492761E (es)
RS (2) RS20050667A (es)
SI (1) SI1492761T1 (es)
TN (1) TNSN04186A1 (es)
TW (1) TWI225864B (es)
UA (2) UA80116C2 (es)
UY (1) UY27738A1 (es)
WO (1) WO2003082807A2 (es)
ZA (1) ZA200407536B (es)

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NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US7419981B2 (en) 2002-08-15 2008-09-02 Pfizer Inc. Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
CA2572324A1 (en) * 2003-07-02 2005-01-13 Warner-Lambert Company Llc Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
CA2540208A1 (en) 2003-09-25 2005-04-07 Warner-Lambert Company Llc Amino acids with affinity for the alpha2delta-protein
RU2344121C2 (ru) * 2003-09-25 2009-01-20 УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си Способы лечения заболеваний у млекопитающих
KR100847922B1 (ko) * 2004-03-12 2008-07-22 워너-램버트 캄파니 엘엘씨 Ｃ1-대칭 비스포스핀 리간드 및 프레가발린의 비대칭합성에서의 이들의 용도
WO2006008612A2 (en) * 2004-07-09 2006-01-26 Warner-Lambert Company Llc Preparation of beta-amino acids having affinity for the alpha-2-delta protein
WO2006092692A1 (en) * 2005-03-01 2006-09-08 Pfizer Limited Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
KR20070107147A (ko) * 2005-03-24 2007-11-06 파마시아 앤드 업존 캄파니 엘엘씨 알파-2-델타 단백질에 친화성을 갖는 광학적으로 순수한베타-아미노산의 제조
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US9266895B2 (en) 2012-09-10 2016-02-23 Principia Biopharma Inc. Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors
US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
SG11201606858RA (en) 2014-02-21 2016-09-29 Principia Biopharma Inc Salts and solid form of a btk inhibitor
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