OA12245A - Benzoamide piperidine compounds as substance P antagonists. - Google Patents
Benzoamide piperidine compounds as substance P antagonists. Download PDFInfo
- Publication number
- OA12245A OA12245A OA1200200312A OA1200200312A OA12245A OA 12245 A OA12245 A OA 12245A OA 1200200312 A OA1200200312 A OA 1200200312A OA 1200200312 A OA1200200312 A OA 1200200312A OA 12245 A OA12245 A OA 12245A
- Authority
- OA
- OAPI
- Prior art keywords
- methyl
- phenyl
- methoxy
- piperidin
- ylamino
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19592200P | 2000-04-10 | 2000-04-10 | |
| US21292200P | 2000-06-20 | 2000-06-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA12245A true OA12245A (en) | 2003-11-10 |
Family
ID=26891472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA1200200312A OA12245A (en) | 2000-04-10 | 2001-04-06 | Benzoamide piperidine compounds as substance P antagonists. |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1272484B1 (is) |
| JP (1) | JP4001486B2 (is) |
| KR (1) | KR20020087134A (is) |
| CN (1) | CN1432011A (is) |
| AP (1) | AP2002002647A0 (is) |
| AR (2) | AR033976A1 (is) |
| AT (1) | ATE299875T1 (is) |
| AU (1) | AU2001246761A1 (is) |
| BG (1) | BG107135A (is) |
| BR (1) | BR0109936A (is) |
| CA (1) | CA2405089A1 (is) |
| CZ (1) | CZ20023213A3 (is) |
| DE (1) | DE60112064T2 (is) |
| EA (1) | EA005409B1 (is) |
| EE (1) | EE200200588A (is) |
| ES (1) | ES2244599T3 (is) |
| HR (1) | HRP20020808A2 (is) |
| HU (1) | HUP0300413A2 (is) |
| IL (1) | IL152209A0 (is) |
| IS (1) | IS6561A (is) |
| MA (1) | MA26891A1 (is) |
| MX (1) | MXPA02010029A (is) |
| NO (1) | NO20024874L (is) |
| NZ (1) | NZ521346A (is) |
| OA (1) | OA12245A (is) |
| PA (1) | PA8515101A1 (is) |
| PE (1) | PE20011311A1 (is) |
| PL (1) | PL358623A1 (is) |
| SK (1) | SK13942002A3 (is) |
| UY (1) | UY26662A1 (is) |
| WO (1) | WO2001077100A2 (is) |
| YU (1) | YU73902A (is) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0109871D0 (en) * | 2001-04-20 | 2001-06-13 | Glaxo Group Ltd | Metering method for particulate material |
| WO2003053929A1 (fr) * | 2001-12-21 | 2003-07-03 | Toray Fine Chemicals Co., Ltd. | Procede de production de derives de cis-piperidine optiquement actifs |
| US20040006135A1 (en) * | 2002-06-19 | 2004-01-08 | Pfizer Inc. | Combination treatment for depression and anxiety |
| CN1662206A (zh) | 2002-06-25 | 2005-08-31 | 惠氏公司 | 硫代－2－羟基吲哚衍生物在治疗皮肤病中的用途 |
| EP1531824A4 (en) | 2002-06-25 | 2005-09-21 | Wyeth Corp | CYCLOTHIOCARBAMATIVE DERIVATIVES AS PR MODULATORS AND THEIR USE IN TREATING SKIN DISORDERS |
| WO2004031190A1 (en) * | 2002-10-04 | 2004-04-15 | Merck Sharp & Dohme Limited | Azabicyclic amine derivatives as nk-1 receptor antagonists |
| WO2004037247A1 (en) * | 2002-10-21 | 2004-05-06 | Irm Llc | Oxindoles with anti-hiv activity |
| US6911544B2 (en) | 2002-10-23 | 2005-06-28 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine |
| PL376836A1 (pl) * | 2002-11-12 | 2006-01-09 | Pfizer Products Inc. | Sposób przekształcania mieszaniny cis-trans podstawionych benzylidenoamin w czysty izomer cis |
| US7022605B2 (en) * | 2002-11-12 | 2006-04-04 | Micron Technology, Inc. | Atomic layer deposition methods |
| AU2003902882A0 (en) * | 2003-06-10 | 2003-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Piperidyl derivatives |
| ES2246687B2 (es) | 2004-02-11 | 2006-11-16 | Miguel Muñoz Saez | Utilizacion de antagonistas no peptidicos de receptores nk1 para la produccion de apoptosis en celulas tumorales. |
| NZ552792A (en) * | 2004-08-20 | 2009-12-24 | Targacept Inc | The use of N-aryl diazaspiracyclic compounds in the treatment of addiction |
| WO2006135783A2 (en) * | 2005-06-10 | 2006-12-21 | Wisconsin Alumni Research Foundation | Compositions and methods for modulating angiogenesis |
| TW200800959A (en) | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
| US20070135380A1 (en) | 2005-08-12 | 2007-06-14 | Radiorx, Inc. | O-nitro compounds, pharmaceutical compositions thereof and uses thereof |
| US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
| DE102006033114A1 (de) * | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclische Azaindol-Derivate |
| TW200901974A (en) | 2007-01-16 | 2009-01-16 | Wyeth Corp | Compounds, compositions, and methods of making and using them |
| WO2008090114A1 (en) | 2007-01-24 | 2008-07-31 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| US8471041B2 (en) | 2010-02-09 | 2013-06-25 | Alliant Techsystems Inc. | Methods of synthesizing and isolating N-(bromoacetyl)-3,3-dinitroazetidine and a composition including the same |
| KR101491938B1 (ko) | 2010-07-14 | 2015-02-10 | 노파르티스 아게 | Ｉｐ 수용체 효능제 헤테로시클릭 화합물 |
| ES2376564B1 (es) | 2010-08-12 | 2013-01-24 | Manuel Vicente Salinas Martín | Utilización de anticuerpos contra los receptores nk1, nk2 y/o nk3, para producir apoptosis en las células tumorales y modificar el estroma, la inmunidad y la vascularización intra y peritumorales, como tratamiento del cáncer. |
| US8664247B2 (en) | 2011-08-26 | 2014-03-04 | Radiorx, Inc. | Acyclic organonitro compounds for use in treating cancer |
| US9139519B2 (en) | 2011-10-07 | 2015-09-22 | Epicentrx, Inc. | Organonitro thioether compounds and medical uses thereof |
| WO2013052803A2 (en) | 2011-10-07 | 2013-04-11 | Radiorx, Inc. | Methods and compositions comprising a nitrite-reductase promoter for treatment of medical disorders and preservation of blood products |
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| US3539584A (en) * | 1967-11-14 | 1970-11-10 | Colgate Palmolive Co | 5-substituted-2,1-benzisothiazolines |
| US4581356A (en) * | 1983-03-22 | 1986-04-08 | Fujisawa Pharmaceutical Co., Ltd. | Triazine derivatives, and pharmaceutical compositions comprising the same |
| JPH0772175B2 (ja) * | 1990-09-28 | 1995-08-02 | フアイザー・インコーポレイテツド | 窒素含有非芳香族複素環の縮合環類似体 |
| TW202432B (is) * | 1991-06-21 | 1993-03-21 | Pfizer | |
| ES2155601T3 (es) * | 1995-07-07 | 2001-05-16 | Pfizer | Compuestos de benzolactama sustituidos como antagonistas de la sustancia p. |
| TWI220143B (en) * | 1998-05-13 | 2004-08-11 | Solvay Pharm Gmbh | Method for stereochemically controlled production of isomerically pure highly substituted azacyclic compounds and novel cyclic compounds, and intermediate products |
| WO2000073312A1 (en) * | 1999-05-26 | 2000-12-07 | Astrazeneca Ab | Compounds |
| SE9901901D0 (sv) * | 1999-05-26 | 1999-05-26 | Astra Ab | Compounds |
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