OA11656A - Genes of the 1-deoxy-D-xylulose biosynthetic pathway. - Google Patents

Genes of the 1-deoxy-D-xylulose biosynthetic pathway. Download PDF

Info

Publication number
OA11656A
OA11656A OA1200100074A OA1200100074A OA11656A OA 11656 A OA11656 A OA 11656A OA 1200100074 A OA1200100074 A OA 1200100074A OA 1200100074 A OA1200100074 A OA 1200100074A OA 11656 A OA11656 A OA 11656A
Authority
OA
OAPI
Prior art keywords
asn
lys
ile
leu
ser
Prior art date
Application number
OA1200100074A
Other languages
English (en)
Inventor
Hassan Jomaa
Original Assignee
Jomaa Pharmaka Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19923567A external-priority patent/DE19923567A1/de
Application filed by Jomaa Pharmaka Gmbh filed Critical Jomaa Pharmaka Gmbh
Publication of OA11656A publication Critical patent/OA11656A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0093—Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01267—1-Deoxy-D-xylulose-5-phosphate reductoisomerase (1.1.1.267)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/07—Oxidoreductases acting on CH or CH2 groups (1.17) with an iron-sulfur protein as acceptor (1.17.7)
    • C12Y117/07001—(E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase (1.17.7.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01—Transketolases and transaldolases (2.2.1)
    • C12Y202/01007—1-Deoxy-D-xylulose-5-phosphate synthase (2.2.1.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
OA1200100074A 1998-09-22 1999-09-22 Genes of the 1-deoxy-D-xylulose biosynthetic pathway. OA11656A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843279 1998-09-22
DE19923567A DE19923567A1 (de) 1998-09-22 1999-05-21 Gene des 1-Desoxy-D-xylulose-Biosynthesewegs

Publications (1)

Publication Number Publication Date
OA11656A true OA11656A (en) 2004-12-08

Family

ID=26048996

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200100074A OA11656A (en) 1998-09-22 1999-09-22 Genes of the 1-deoxy-D-xylulose biosynthetic pathway.

Country Status (23)

Country Link
EP (1) EP1115849B1 (id)
JP (1) JP2002526061A (id)
CN (1) CN1319134A (id)
AP (1) AP2001002104A0 (id)
AT (1) ATE317007T1 (id)
AU (1) AU767213B2 (id)
BG (1) BG105361A (id)
BR (1) BR9914028A (id)
CA (1) CA2343919A1 (id)
CZ (1) CZ2001990A3 (id)
DE (1) DE59913101D1 (id)
EE (1) EE200100174A (id)
HR (1) HRP20010215A2 (id)
HU (1) HUP0203649A2 (id)
ID (1) ID29772A (id)
IL (1) IL141888A0 (id)
IS (1) IS5872A (id)
NO (1) NO20011459L (id)
OA (1) OA11656A (id)
PL (1) PL348428A1 (id)
SK (1) SK3922001A3 (id)
TR (1) TR200100836T2 (id)
WO (1) WO2000017233A2 (id)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999053071A1 (fr) 1998-04-14 1999-10-21 Kyowa Hakko Kogyo Co., Ltd. Procede de production de composes isoprenoides au moyen de micro-organismes et procede de detection de composes ayant une action antibacterienne ou herbicide
JP2002541851A (ja) 1999-04-15 2002-12-10 カルジーン エルエルシー イソプレノイド合成に関与するタンパク質の核酸配列
DE19918949A1 (de) * 1999-04-27 2000-11-23 Basf Ag Überexpression einer DNA-Sequenz codierend für eine 1-Desoxy-D-Xylulose-5-Phosphat Reduktoisomerase in Pflanzen
IL146347A0 (en) * 1999-05-21 2002-07-25 Jomaa Pharmaka Gmbh Use of genes of the deoxy-d-xylulose phosphate biosynthetic pathway for altering the concentration of isoprenoid
US7122331B1 (en) 1999-08-04 2006-10-17 Wolfgang Eisenreich Isoprenoid biosynthesis
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
DE10021688A1 (de) * 2000-05-05 2001-11-15 Hassan Jomaa Gene des 1-Desoxy-D-xylulose-Biosynthesewegs
DE10027821A1 (de) * 2000-06-05 2001-12-06 Adelbert Bacher Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg
CA2418436C (en) 2000-08-07 2017-07-11 Monsanto Technology, Llc Methyl-d-erythritol phosphate pathway genes
DE10201458A1 (de) 2001-04-11 2002-10-17 Adelbert Bacher Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg
ATE419366T1 (de) 2001-05-09 2009-01-15 Monsanto Technology Llc Tyra-gene und ihre verwendung
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
KR100906018B1 (ko) * 2001-07-20 2009-07-06 바이오에이전시 아게 감마/델타 ｔ세포 활성화를 위한 유기-인 화합물
US7244877B2 (en) 2001-08-17 2007-07-17 Monsanto Technology Llc Methyltransferase from cotton and uses thereof
AR036962A1 (es) 2001-10-25 2004-10-13 Monsanto Technology Llc Metiltransferasas aromaticas y usos de las mismas
BRPI0308740B1 (pt) 2002-03-19 2018-11-21 Monsanto Technology Llc molécula de ácido nucléico codificando uma homogentisato prenil transferase (“hpt”) e método de produzir planta tendo semente com nível de tocoferol aumentado
EP1546334A4 (en) 2002-08-05 2007-01-03 Monsanto Technology Llc GENES ASSOCIATED WITH TOCOPHEROL BIOSYNTHESIS AND USES THEREOF
CN106978425B (zh) * 2017-02-17 2019-10-18 华中农业大学 东方巴贝斯虫1-脱氧-d-木酮糖-5-磷酸还原异构酶基因及其编码的蛋白
JP2021505154A (ja) 2017-12-07 2021-02-18 ザイマージェン インコーポレイテッド 発酵によって（６ｅ）−８−ヒドロキシゲラニオールを生産するための設計された生合成経路
CN111868047A (zh) 2017-12-21 2020-10-30 齐默尔根公司 荆芥内半缩醛氧化还原酶、荆芥内半缩醛合酶和能够产生荆芥内酯的微生物
CN109342634A (zh) * 2018-12-07 2019-02-15 西北大学 一种柱前衍生-hplc测定dxs酶催化活性的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19752700A1 (de) * 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Desoxy-D-xylulose-5-phosphat Synthase, Verfahren zur Identifizierung von Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase und Effektoren der 1-Desoxy-D-xylulose-5-phosphat Synthase
SK15232000A3 (sk) * 1998-04-14 2001-05-10 Hassan Jomaa Spôsob identifikácie chemických účinných látok a prostriedkov inhibície biosyntetickej cesty 1-deoxy-d-xylulóza-5-fosfátu

Also Published As

Publication number Publication date
IS5872A (is) 2001-02-28
SK3922001A3 (en) 2001-09-11
DE59913101D1 (de) 2006-04-13
AU767213B2 (en) 2003-11-06
WO2000017233A3 (de) 2000-05-25
WO2000017233A2 (de) 2000-03-30
EP1115849B1 (de) 2006-02-01
BG105361A (en) 2001-10-31
NO20011459L (no) 2001-05-22
PL348428A1 (en) 2002-05-20
TR200100836T2 (tr) 2001-10-22
AP2001002104A0 (en) 2001-03-31
ID29772A (id) 2001-10-11
JP2002526061A (ja) 2002-08-20
CA2343919A1 (en) 2000-03-30
HUP0203649A2 (hu) 2003-02-28
IL141888A0 (en) 2002-03-10
CZ2001990A3 (cs) 2002-01-16
NO20011459D0 (no) 2001-03-22
CN1319134A (zh) 2001-10-24
BR9914028A (pt) 2001-07-03
EE200100174A (et) 2002-08-15
AU6194799A (en) 2000-04-10
EP1115849A2 (de) 2001-07-18
HRP20010215A2 (en) 2002-06-30
ATE317007T1 (de) 2006-02-15

Similar Documents

Publication Publication Date Title
OA11656A (en) Genes of the 1-deoxy-D-xylulose biosynthetic pathway.
Ma et al. Molecular cloning and characterization of GPA1, a G protein alpha subunit gene from Arabidopsis thaliana.
US20030166197A1 (en) Ethylene insensitive plants
Reverdatto et al. A multisubunit acetyl coenzyme A carboxylase from soybean
CN101883783A (zh) 具有增强的产量相关性状的植物及其制备方法
CN111620935B (zh) ZmCEP1基因在调控玉米籽粒发育中的应用
CN113061171B (zh) 抗稻瘟病蛋白和基因、分离的核酸及其应用
CN114540369B (zh) OsBEE1基因在提高水稻产量中的应用
CN107326035B (zh) 一种调控水稻粒型和叶色的去泛素化酶基因ubp5及其应用
US6639130B2 (en) Plant sterol reductases and uses thereof
CN101553570A (zh) 通过调控谷氨酰胺合成酶的活性改进植物的籽粒的生产能力
Vogel et al. Expression of the two maize TATA binding protein genes and function of the encoded TBP proteins by complementation in yeast.
Bhattacharjee et al. Genomic organization and chromosomal localization of the Asna1 gene, a mouse homologue of a bacterial arsenic-translocating ATPase gene
CN107936099B (zh) Lhap1蛋白及其编码基因在调控植物光合作用中的应用
CN112708603B (zh) 水稻are2基因在植物氮代谢调控中的应用
CN115819536A (zh) 新型Zn-尼克酰胺转运蛋白及其应用
MXPA01011894A (es) Uso de genes de las trayectorias biosinteticas de fosfato de desoxi-d-xilulosa para alterar la concentracion de isoprenoides.
CN115247184A (zh) 一种籽粒粒型及产量控制基因及其应用
AU727951B2 (en) Method of changing the composition of the phospholipid produced by the living body and recombinant vector therefor
CN113929756A (zh) Gl11蛋白和编码gl11蛋白的基因在调控水稻粒形和千粒重中的应用
CN114891800B (zh) 玉米穗长基因及其应用
US20030199684A1 (en) Novel gene involved in brassinosteroid responses
MXPA01002978A (en) Genes of the 1-desoxy-d-xylulose biosynthetic pathway
CN113215156B (zh) 一种利用CRISPR/Cas9技术高效创制香味玉米的方法
CN114058718B (zh) 一种鉴别荷斯坦牛优质高产的分子标记及其制备方法