BG105361A - Genes of the 1-desoxy-d-xylulose biosynthetic pathway - Google Patents
Genes of the 1-desoxy-d-xylulose biosynthetic pathwayInfo
- Publication number
- BG105361A BG105361A BG105361A BG10536101A BG105361A BG 105361 A BG105361 A BG 105361A BG 105361 A BG105361 A BG 105361A BG 10536101 A BG10536101 A BG 10536101A BG 105361 A BG105361 A BG 105361A
- Authority
- BG
- Bulgaria
- Prior art keywords
- xylulose
- desoxy
- biosynthetic pathway
- genes
- gene
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0093—Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01267—1-Deoxy-D-xylulose-5-phosphate reductoisomerase (1.1.1.267)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
- C12Y117/07—Oxidoreductases acting on CH or CH2 groups (1.17) with an iron-sulfur protein as acceptor (1.17.7)
- C12Y117/07001—(E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase (1.17.7.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01007—1-Deoxy-D-xylulose-5-phosphate synthase (2.2.1.7)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The invention relates to the 1-desoxy-D-xylulose-5-phosphate reductoisomerase gene, the 1-desoxy-D-xylulose-5-phosphate-synthase gene and the gcpE gene of the 1-deoxy-D-xylulose biosynthetic pathway and to their use for the transforming vectors, host organisms and plants and for determining substances that inhibit this biosynthetic pathway. 18 claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843279 | 1998-09-22 | ||
DE19923567A DE19923567A1 (en) | 1998-09-22 | 1999-05-21 | Genes of the 1-deoxy-D-xylulose biosynthetic pathway |
PCT/EP1999/007055 WO2000017233A2 (en) | 1998-09-22 | 1999-09-22 | Genes of the 1-desoxy-d-xylulose biosynthetic pathway |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105361A true BG105361A (en) | 2001-10-31 |
Family
ID=26048996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105361A BG105361A (en) | 1998-09-22 | 2001-03-19 | Genes of the 1-desoxy-d-xylulose biosynthetic pathway |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1115849B1 (en) |
JP (1) | JP2002526061A (en) |
CN (1) | CN1319134A (en) |
AP (1) | AP2001002104A0 (en) |
AT (1) | ATE317007T1 (en) |
AU (1) | AU767213B2 (en) |
BG (1) | BG105361A (en) |
BR (1) | BR9914028A (en) |
CA (1) | CA2343919A1 (en) |
CZ (1) | CZ2001990A3 (en) |
DE (1) | DE59913101D1 (en) |
EE (1) | EE200100174A (en) |
HR (1) | HRP20010215A2 (en) |
HU (1) | HUP0203649A2 (en) |
ID (1) | ID29772A (en) |
IL (1) | IL141888A0 (en) |
IS (1) | IS5872A (en) |
NO (1) | NO20011459L (en) |
OA (1) | OA11656A (en) |
PL (1) | PL348428A1 (en) |
SK (1) | SK3922001A3 (en) |
TR (1) | TR200100836T2 (en) |
WO (1) | WO2000017233A2 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2736981A1 (en) | 1998-04-14 | 1999-10-21 | Kyowa Hakko Bio Co., Ltd. | Process for producing isoprenoid compounds by microorganisms |
ATE316578T1 (en) | 1999-04-15 | 2006-02-15 | Calgene Llc | NUCLEIC ACID SEQUENCES FOR PROTEINS INVOLVED IN TOCOPHEROL BIOSYNTHESIS |
DE19918949A1 (en) * | 1999-04-27 | 2000-11-23 | Basf Ag | Overexpression of a DNA sequence coding for a 1-deoxy-D-xylulose-5-phosphate reductoisomerase in plants |
EP1179187A1 (en) * | 1999-05-21 | 2002-02-13 | Jomaa Pharmaka GmbH | Use of genes of the deoxy-d-xylulose phosphate biosynthetic pathway for altering the concentration of isoprenoid |
WO2001011055A1 (en) | 1999-08-04 | 2001-02-15 | Adelbert Bacher | Isoprenoid biosynthesis |
US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
DE10021688A1 (en) * | 2000-05-05 | 2001-11-15 | Hassan Jomaa | New DNA sequences involved in isoprenoid biosynthesis, useful in screening for compounds with e.g. antimicrobial and herbicidal activity |
DE10027821A1 (en) | 2000-06-05 | 2001-12-06 | Adelbert Bacher | New intermediate in isoprenoid biosynthesis, useful in screening for potential herbicides, comprises mutant encoding-enzymes sequences for imparting herbicide resistance |
CA2418436C (en) | 2000-08-07 | 2017-07-11 | Monsanto Technology, Llc | Methyl-d-erythritol phosphate pathway genes |
DE10201458A1 (en) | 2001-04-11 | 2002-10-17 | Adelbert Bacher | New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies |
US7161061B2 (en) | 2001-05-09 | 2007-01-09 | Monsanto Technology Llc | Metabolite transporters |
EP1392106B1 (en) | 2001-05-09 | 2008-12-31 | Monsanto Technology LLC | Tyra genes and uses thereof |
EP1408984B1 (en) * | 2001-07-20 | 2008-10-22 | BioAgency AG | Organo-phosphorous compounds for activating gamma/delta t cells |
US7244877B2 (en) | 2001-08-17 | 2007-07-17 | Monsanto Technology Llc | Methyltransferase from cotton and uses thereof |
AU2002342114B2 (en) | 2001-10-25 | 2008-07-31 | Monsanto Technology Llc | Aromatic methyltransferases and uses thereof |
BR0308740A (en) | 2002-03-19 | 2007-01-09 | Monsanto Technology Llc | homogenous prenyl transferase ("hpt") nucleic acids and polypeptides, and their use |
BR0313270A (en) | 2002-08-05 | 2005-08-02 | Monsanto Technology Llc | Genes related to tocopherol biosynthesis and uses |
CN106978425B (en) * | 2017-02-17 | 2019-10-18 | 华中农业大学 | The albumen of Babesia orientalis 1-deoxy-D-xylulose -5- phosphoric acid reduction isomerase gene and its coding |
EP3720944A1 (en) | 2017-12-07 | 2020-10-14 | Zymergen Inc. | Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation |
CN111868047A (en) | 2017-12-21 | 2020-10-30 | 齐默尔根公司 | Nepetalactol oxidoreductase, nepetalactol synthase and microorganism capable of producing nepetalactone |
CN109342634A (en) * | 2018-12-07 | 2019-02-15 | 西北大学 | A kind of method of column front derivation-HPLC measurement DXS enzymatic activity |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19752700A1 (en) * | 1997-11-28 | 1999-06-02 | Hoechst Schering Agrevo Gmbh | 1-Deoxy-D-xylulose-5-phosphate synthase protein and modulators |
TR200002972T2 (en) * | 1998-04-14 | 2001-01-22 | Jomaa Hassan | Process for determination of active substances and chemical active substances for inhibition of the 1-deoxy-D-xylulose-5-phosphate biosynthesis pathway |
-
1999
- 1999-09-22 ID IDW20010573A patent/ID29772A/en unknown
- 1999-09-22 CN CN99811200A patent/CN1319134A/en active Pending
- 1999-09-22 CZ CZ2001990A patent/CZ2001990A3/en unknown
- 1999-09-22 HU HU0203649A patent/HUP0203649A2/en unknown
- 1999-09-22 TR TR2001/00836T patent/TR200100836T2/en unknown
- 1999-09-22 JP JP2000574141A patent/JP2002526061A/en active Pending
- 1999-09-22 WO PCT/EP1999/007055 patent/WO2000017233A2/en active IP Right Grant
- 1999-09-22 AU AU61947/99A patent/AU767213B2/en not_active Ceased
- 1999-09-22 EE EEP200100174A patent/EE200100174A/en unknown
- 1999-09-22 SK SK392-2001A patent/SK3922001A3/en unknown
- 1999-09-22 EP EP99948831A patent/EP1115849B1/en not_active Expired - Lifetime
- 1999-09-22 CA CA002343919A patent/CA2343919A1/en not_active Abandoned
- 1999-09-22 BR BR9914028-4A patent/BR9914028A/en not_active IP Right Cessation
- 1999-09-22 IL IL14188899A patent/IL141888A0/en unknown
- 1999-09-22 AP APAP/P/2001/002104A patent/AP2001002104A0/en unknown
- 1999-09-22 DE DE59913101T patent/DE59913101D1/en not_active Expired - Lifetime
- 1999-09-22 PL PL99348428A patent/PL348428A1/en not_active Application Discontinuation
- 1999-09-22 OA OA1200100074A patent/OA11656A/en unknown
- 1999-09-22 AT AT99948831T patent/ATE317007T1/en not_active IP Right Cessation
-
2001
- 2001-02-28 IS IS5872A patent/IS5872A/en unknown
- 2001-03-19 BG BG105361A patent/BG105361A/en unknown
- 2001-03-21 HR HR20010215A patent/HRP20010215A2/en not_active Application Discontinuation
- 2001-03-22 NO NO20011459A patent/NO20011459L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1319134A (en) | 2001-10-24 |
BR9914028A (en) | 2001-07-03 |
AU6194799A (en) | 2000-04-10 |
TR200100836T2 (en) | 2001-10-22 |
OA11656A (en) | 2004-12-08 |
SK3922001A3 (en) | 2001-09-11 |
EE200100174A (en) | 2002-08-15 |
IS5872A (en) | 2001-02-28 |
AU767213B2 (en) | 2003-11-06 |
HUP0203649A2 (en) | 2003-02-28 |
CZ2001990A3 (en) | 2002-01-16 |
AP2001002104A0 (en) | 2001-03-31 |
WO2000017233A3 (en) | 2000-05-25 |
NO20011459D0 (en) | 2001-03-22 |
JP2002526061A (en) | 2002-08-20 |
DE59913101D1 (en) | 2006-04-13 |
ATE317007T1 (en) | 2006-02-15 |
HRP20010215A2 (en) | 2002-06-30 |
NO20011459L (en) | 2001-05-22 |
EP1115849B1 (en) | 2006-02-01 |
CA2343919A1 (en) | 2000-03-30 |
IL141888A0 (en) | 2002-03-10 |
ID29772A (en) | 2001-10-11 |
EP1115849A2 (en) | 2001-07-18 |
WO2000017233A2 (en) | 2000-03-30 |
PL348428A1 (en) | 2002-05-20 |
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