EE200100174A - Genes for the 1-deoxy-D-xylulose biosynthetic pathway - Google Patents

Genes for the 1-deoxy-D-xylulose biosynthetic pathway

Info

Publication number
EE200100174A
EE200100174A EEP200100174A EEP200100174A EE200100174A EE 200100174 A EE200100174 A EE 200100174A EE P200100174 A EEP200100174 A EE P200100174A EE P200100174 A EEP200100174 A EE P200100174A EE 200100174 A EE200100174 A EE 200100174A
Authority
EE
Estonia
Prior art keywords
xylulose
deoxy
genes
biosynthetic pathway
biosynthetic
Prior art date
Application number
EEP200100174A
Other languages
Estonian (et)
Inventor
Jomaa Hassan
Original Assignee
Jomaa Pharmaka Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19923567A external-priority patent/DE19923567A1/en
Application filed by Jomaa Pharmaka Gmbh filed Critical Jomaa Pharmaka Gmbh
Publication of EE200100174A publication Critical patent/EE200100174A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0093Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1022Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/012671-Deoxy-D-xylulose-5-phosphate reductoisomerase (1.1.1.267)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y117/00Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/07Oxidoreductases acting on CH or CH2 groups (1.17) with an iron-sulfur protein as acceptor (1.17.7)
    • C12Y117/07001(E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase (1.17.7.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y202/00Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01Transketolases and transaldolases (2.2.1)
    • C12Y202/010071-Deoxy-D-xylulose-5-phosphate synthase (2.2.1.7)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EEP200100174A 1998-09-22 1999-09-22 Genes for the 1-deoxy-D-xylulose biosynthetic pathway EE200100174A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19843279 1998-09-22
DE19923567A DE19923567A1 (en) 1998-09-22 1999-05-21 Genes of the 1-deoxy-D-xylulose biosynthetic pathway
PCT/EP1999/007055 WO2000017233A2 (en) 1998-09-22 1999-09-22 Genes of the 1-desoxy-d-xylulose biosynthetic pathway

Publications (1)

Publication Number Publication Date
EE200100174A true EE200100174A (en) 2002-08-15

Family

ID=26048996

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100174A EE200100174A (en) 1998-09-22 1999-09-22 Genes for the 1-deoxy-D-xylulose biosynthetic pathway

Country Status (23)

Country Link
EP (1) EP1115849B1 (en)
JP (1) JP2002526061A (en)
CN (1) CN1319134A (en)
AP (1) AP2001002104A0 (en)
AT (1) ATE317007T1 (en)
AU (1) AU767213B2 (en)
BG (1) BG105361A (en)
BR (1) BR9914028A (en)
CA (1) CA2343919A1 (en)
CZ (1) CZ2001990A3 (en)
DE (1) DE59913101D1 (en)
EE (1) EE200100174A (en)
HR (1) HRP20010215A2 (en)
HU (1) HUP0203649A2 (en)
ID (1) ID29772A (en)
IL (1) IL141888A0 (en)
IS (1) IS5872A (en)
NO (1) NO20011459L (en)
OA (1) OA11656A (en)
PL (1) PL348428A1 (en)
SK (1) SK3922001A3 (en)
TR (1) TR200100836T2 (en)
WO (1) WO2000017233A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6806076B1 (en) 1998-04-14 2004-10-19 Kyowa Hakko Kogyo Co., Ltd. Process for producing isoprenoid compounds by microorganisms and a method for screening compounds with antibiotic or weeding activity
BR0010616A (en) 1999-04-15 2002-05-07 Calgene Llc Nucleic acid sequences to proteins involved in isoprenoid synthesis
DE19918949A1 (en) * 1999-04-27 2000-11-23 Basf Ag Overexpression of a DNA sequence coding for a 1-deoxy-D-xylulose-5-phosphate reductoisomerase in plants
BR0011289A (en) * 1999-05-21 2002-02-26 Jomaa Pharmaka Gmbh Use of genes in the deoxy-d-xylulose phosphate biosynthetic pathways to alter the isoprenoid concentration
EP1198575B1 (en) 1999-08-04 2007-09-19 Adelbert Bacher Isoprenoid biosynthesis
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
DE10021688A1 (en) * 2000-05-05 2001-11-15 Hassan Jomaa New DNA sequences involved in isoprenoid biosynthesis, useful in screening for compounds with e.g. antimicrobial and herbicidal activity
DE10027821A1 (en) * 2000-06-05 2001-12-06 Adelbert Bacher New intermediate in isoprenoid biosynthesis, useful in screening for potential herbicides, comprises mutant encoding-enzymes sequences for imparting herbicide resistance
WO2002012478A2 (en) * 2000-08-07 2002-02-14 Monsanto Technology, Llc Methyl-d-erythritol phosphate pathway genes
DE10201458A1 (en) 2001-04-11 2002-10-17 Adelbert Bacher New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
JP2004533244A (en) 2001-05-09 2004-11-04 モンサント テクノロジー リミテッド ライアビリティー カンパニー TyrA gene and uses thereof
CA2453817C (en) * 2001-07-20 2011-09-20 Bioagency Ag Organophosphorus compounds for the activation of gamma/delta t-cells
US7244877B2 (en) 2001-08-17 2007-07-17 Monsanto Technology Llc Methyltransferase from cotton and uses thereof
CN100400661C (en) 2001-10-25 2008-07-09 孟山都技术有限公司 Aromatic methyltransferases and uses thereof
CA2478957C (en) 2002-03-19 2013-07-02 Monsanto Technology, Llc Homogentisate prenyl transferase ("hpt") nucleic acids and polypeptides, and uses thereof
CN1681928A (en) 2002-08-05 2005-10-12 孟山都技术公司 Tocopherol biosynthesis related genes and uses thereof
CN106978425B (en) * 2017-02-17 2019-10-18 华中农业大学 The albumen of Babesia orientalis 1-deoxy-D-xylulose -5- phosphoric acid reduction isomerase gene and its coding
KR20200095534A (en) 2017-12-07 2020-08-10 지머젠 인코포레이티드 Biosynthetic pathway engineered for the production of (6E)-8-hydroxygeraniol by fermentation
JP2021506316A (en) 2017-12-21 2021-02-22 ザイマージェン インコーポレイテッド Microorganisms capable of producing nepetalactor oxidoreductase, nepetalactor synthase, and nepetalactone
CN109342634A (en) * 2018-12-07 2019-02-15 西北大学 A kind of method of column front derivation-HPLC measurement DXS enzymatic activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19752700A1 (en) * 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Deoxy-D-xylulose-5-phosphate synthase protein and modulators
WO1999052938A2 (en) * 1998-04-14 1999-10-21 Jomaa Hassan Identification of chemical active agents for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthetic pathway in parasites

Also Published As

Publication number Publication date
TR200100836T2 (en) 2001-10-22
CZ2001990A3 (en) 2002-01-16
WO2000017233A2 (en) 2000-03-30
SK3922001A3 (en) 2001-09-11
AU767213B2 (en) 2003-11-06
ID29772A (en) 2001-10-11
OA11656A (en) 2004-12-08
AP2001002104A0 (en) 2001-03-31
EP1115849B1 (en) 2006-02-01
CA2343919A1 (en) 2000-03-30
PL348428A1 (en) 2002-05-20
EP1115849A2 (en) 2001-07-18
WO2000017233A3 (en) 2000-05-25
JP2002526061A (en) 2002-08-20
DE59913101D1 (en) 2006-04-13
IS5872A (en) 2001-02-28
BR9914028A (en) 2001-07-03
BG105361A (en) 2001-10-31
CN1319134A (en) 2001-10-24
HUP0203649A2 (en) 2003-02-28
ATE317007T1 (en) 2006-02-15
NO20011459L (en) 2001-05-22
HRP20010215A2 (en) 2002-06-30
AU6194799A (en) 2000-04-10
NO20011459D0 (en) 2001-03-22
IL141888A0 (en) 2002-03-10

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