ZA981659B - Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use - Google Patents
Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their useInfo
- Publication number
- ZA981659B ZA981659B ZA981659A ZA981659A ZA981659B ZA 981659 B ZA981659 B ZA 981659B ZA 981659 A ZA981659 A ZA 981659A ZA 981659 A ZA981659 A ZA 981659A ZA 981659 B ZA981659 B ZA 981659B
- Authority
- ZA
- South Africa
- Prior art keywords
- acarbose
- actinoplanes
- acb
- biosynthesis
- metabolism genes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19708127A DE19708127A1 (en) | 1997-02-28 | 1997-02-28 | Acarbose acb clusters: isolation of other genes of acarbose biosynthesis and acarbose metabolism from Actinoplanes sp. SE 50/110 and its use |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA981659B true ZA981659B (en) | 1998-09-10 |
Family
ID=7821816
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA981659A ZA981659B (en) | 1997-02-28 | 1998-02-27 | Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0968294A1 (en) |
KR (1) | KR20000075777A (en) |
CN (1) | CN1249001A (en) |
AU (1) | AU6296898A (en) |
BG (1) | BG103672A (en) |
BR (1) | BR9807640A (en) |
CA (1) | CA2282735A1 (en) |
CZ (1) | CZ9903054A3 (en) |
DE (1) | DE19708127A1 (en) |
HU (1) | HUP0000889A2 (en) |
IL (1) | IL131433A0 (en) |
NO (1) | NO994164D0 (en) |
PL (1) | PL335369A1 (en) |
WO (1) | WO1998038313A1 (en) |
ZA (1) | ZA981659B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0796915A3 (en) * | 1996-03-22 | 1999-04-14 | Bayer Ag | Process for the preparation and use of acarviosyl-transferase in the conversion of ascarbose-homologous in acarbose and in the preparation of acarbose-homologous |
TW201217533A (en) * | 2010-08-04 | 2012-05-01 | Bayer Pharma AG | Genomics of actinoplanes utahensis |
CN106167814B (en) * | 2016-08-31 | 2019-08-09 | 河北华荣制药有限公司 | A method of improving acarbose fermentation unit |
CN106566796B (en) * | 2016-10-28 | 2020-11-10 | 上海交通大学 | Genetic operation system of acarbose producing bacterium Actinoplanes spp |
EP4045520A1 (en) * | 2019-10-16 | 2022-08-24 | Bayer Aktiengesellschaft | Methods for the improved formation of acarbose |
CN112592878B (en) * | 2020-12-25 | 2022-08-26 | 上海交通大学 | Method for enhancing expression of positive regulatory protein gene to improve acarbose fermentation level |
CN113444670A (en) * | 2021-07-28 | 2021-09-28 | 山东鲁抗医药股份有限公司 | Screening method and culture method of high-activity acarbose producing strain |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19507214A1 (en) * | 1995-03-02 | 1996-10-31 | Bayer Ag | Acarbose biosynthesis genes from Actinoplanes sp., Process for their isolation and their use |
DE19622783A1 (en) * | 1996-06-07 | 1997-12-11 | Hoechst Ag | Isolation of the biosynthetic genes for pseudo-oligosaccharides from Streptomyces glaucescens GLA.O and their use |
-
1997
- 1997-02-28 DE DE19708127A patent/DE19708127A1/en not_active Withdrawn
-
1998
- 1998-02-16 AU AU62968/98A patent/AU6296898A/en not_active Abandoned
- 1998-02-16 HU HU0000889A patent/HUP0000889A2/en unknown
- 1998-02-16 IL IL13143398A patent/IL131433A0/en unknown
- 1998-02-16 BR BR9807640A patent/BR9807640A/en not_active Application Discontinuation
- 1998-02-16 EP EP98906953A patent/EP0968294A1/en not_active Withdrawn
- 1998-02-16 CN CN98802927A patent/CN1249001A/en active Pending
- 1998-02-16 CZ CZ993054A patent/CZ9903054A3/en unknown
- 1998-02-16 KR KR1019997007849A patent/KR20000075777A/en not_active Application Discontinuation
- 1998-02-16 CA CA002282735A patent/CA2282735A1/en not_active Abandoned
- 1998-02-16 PL PL98335369A patent/PL335369A1/en unknown
- 1998-02-16 WO PCT/EP1998/000862 patent/WO1998038313A1/en not_active Application Discontinuation
- 1998-02-27 ZA ZA981659A patent/ZA981659B/en unknown
-
1999
- 1999-08-20 BG BG103672A patent/BG103672A/en unknown
- 1999-08-27 NO NO994164A patent/NO994164D0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE19708127A1 (en) | 1998-09-03 |
IL131433A0 (en) | 2001-01-28 |
NO994164L (en) | 1999-08-27 |
HUP0000889A2 (en) | 2000-07-28 |
CZ9903054A3 (en) | 1999-11-17 |
AU6296898A (en) | 1998-09-18 |
BG103672A (en) | 2000-05-31 |
EP0968294A1 (en) | 2000-01-05 |
BR9807640A (en) | 2000-03-21 |
PL335369A1 (en) | 2000-04-25 |
NO994164D0 (en) | 1999-08-27 |
CA2282735A1 (en) | 1998-09-03 |
KR20000075777A (en) | 2000-12-26 |
CN1249001A (en) | 2000-03-29 |
WO1998038313A1 (en) | 1998-09-03 |
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