ZA981659B - Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use - Google Patents

Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use

Info

Publication number
ZA981659B
ZA981659B ZA981659A ZA981659A ZA981659B ZA 981659 B ZA981659 B ZA 981659B ZA 981659 A ZA981659 A ZA 981659A ZA 981659 A ZA981659 A ZA 981659A ZA 981659 B ZA981659 B ZA 981659B
Authority
ZA
South Africa
Prior art keywords
acarbose
actinoplanes
acb
biosynthesis
metabolism genes
Prior art date
Application number
ZA981659A
Inventor
Anneliese Crueger
Heiner Apeler
Werner Schroder
Hermann Pape
Klaus Goeke
Wolfgang Piepersberg
Jurgen Distler
Uribe Paz Mart Diaz-Guardamino
Martin Jarling
Ansgar Stratmann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA981659B publication Critical patent/ZA981659B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA981659A 1997-02-28 1998-02-27 Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use ZA981659B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19708127A DE19708127A1 (en) 1997-02-28 1997-02-28 Acarbose acb clusters: isolation of other genes of acarbose biosynthesis and acarbose metabolism from Actinoplanes sp. SE 50/110 and its use

Publications (1)

Publication Number Publication Date
ZA981659B true ZA981659B (en) 1998-09-10

Family

ID=7821816

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA981659A ZA981659B (en) 1997-02-28 1998-02-27 Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use

Country Status (15)

Country Link
EP (1) EP0968294A1 (en)
KR (1) KR20000075777A (en)
CN (1) CN1249001A (en)
AU (1) AU6296898A (en)
BG (1) BG103672A (en)
BR (1) BR9807640A (en)
CA (1) CA2282735A1 (en)
CZ (1) CZ9903054A3 (en)
DE (1) DE19708127A1 (en)
HU (1) HUP0000889A2 (en)
IL (1) IL131433A0 (en)
NO (1) NO994164D0 (en)
PL (1) PL335369A1 (en)
WO (1) WO1998038313A1 (en)
ZA (1) ZA981659B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796915A3 (en) * 1996-03-22 1999-04-14 Bayer Ag Process for the preparation and use of acarviosyl-transferase in the conversion of ascarbose-homologous in acarbose and in the preparation of acarbose-homologous
TW201217533A (en) * 2010-08-04 2012-05-01 Bayer Pharma AG Genomics of actinoplanes utahensis
CN106167814B (en) * 2016-08-31 2019-08-09 河北华荣制药有限公司 A method of improving acarbose fermentation unit
CN106566796B (en) * 2016-10-28 2020-11-10 上海交通大学 Genetic operation system of acarbose producing bacterium Actinoplanes spp
CN112592878B (en) * 2020-12-25 2022-08-26 上海交通大学 Method for enhancing expression of positive regulatory protein gene to improve acarbose fermentation level
CN113444670A (en) * 2021-07-28 2021-09-28 山东鲁抗医药股份有限公司 Screening method and culture method of high-activity acarbose producing strain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19507214A1 (en) * 1995-03-02 1996-10-31 Bayer Ag Acarbose biosynthesis genes from Actinoplanes sp., Process for their isolation and their use
DE19622783A1 (en) * 1996-06-07 1997-12-11 Hoechst Ag Isolation of the biosynthetic genes for pseudo-oligosaccharides from Streptomyces glaucescens GLA.O and their use

Also Published As

Publication number Publication date
HUP0000889A2 (en) 2000-07-28
BG103672A (en) 2000-05-31
KR20000075777A (en) 2000-12-26
NO994164L (en) 1999-08-27
CA2282735A1 (en) 1998-09-03
WO1998038313A1 (en) 1998-09-03
DE19708127A1 (en) 1998-09-03
CZ9903054A3 (en) 1999-11-17
PL335369A1 (en) 2000-04-25
AU6296898A (en) 1998-09-18
IL131433A0 (en) 2001-01-28
EP0968294A1 (en) 2000-01-05
CN1249001A (en) 2000-03-29
BR9807640A (en) 2000-03-21
NO994164D0 (en) 1999-08-27

Similar Documents

Publication Publication Date Title
PL330847A1 (en) Plant gene of p-hydroxyphenylpyrogronianic dioxygenase
GB2297572B (en) Well valve
IL116935A0 (en) Venlafaxine for the treatment of hypothalmic amenorrhea
HUP0004393A3 (en) Pesticide against plant-pathogenic microorganisms
GB9526522D0 (en) Valve arrangement
ZA981659B (en) Acarbose ACB cluster isolation of further acarbose biosynthesis and acarbose metabolism genes from actinoplanes SP.SE50/110 and their use
HUP9600500A2 (en) Genes from actinoplanes sp. for biosynthesis of acarbose, process for their isolation and their use
GB9506051D0 (en) Gene expression
GB2305489B (en) Valve
ZA968873B (en) Isomerisation of equillin
GB9503341D0 (en) Valve
PL326300A1 (en) Valve
GB2305713B (en) Valve
GB9514789D0 (en) Valves
GB9519701D0 (en) Valve
GB9516228D0 (en) Anti-butterfly valve
TW301911U (en) Improved structure of open valve
GB2317673B (en) Valves
TW302062U (en) Improved structure of post-plug type valve
TW441733U (en) Structure improvement of ball-shaped valve
GB9615797D0 (en) Gene expression
GB9525962D0 (en) Gene expression
GB2300403B (en) Valve
GB9521711D0 (en) Gene therapy
GB9520433D0 (en) Gene therapy