HUP0000889A2 - Acarbose (acb) cluster from actinoplanes sp. se 50/110 - Google Patents

Acarbose (acb) cluster from actinoplanes sp. se 50/110

Info

Publication number
HUP0000889A2
HUP0000889A2 HU0000889A HUP0000889A HUP0000889A2 HU P0000889 A2 HUP0000889 A2 HU P0000889A2 HU 0000889 A HU0000889 A HU 0000889A HU P0000889 A HUP0000889 A HU P0000889A HU P0000889 A2 HUP0000889 A2 HU P0000889A2
Authority
HU
Hungary
Prior art keywords
actinoplanes
acb
acarbose
cluster
Prior art date
Application number
HU0000889A
Other languages
Hungarian (hu)
Inventor
Apeler Heiner Dr
Crueger Anneliese Dr
Uribe Paz Mart Diaz-Guardamino
Distler Juergen Dr
Klaus Goeke
Martin Jarling
Pape Hermann Dr
Piepersberg Wolfgang Dr
Schroeder Werner Dr
Ansgar Stratmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of HUP0000889A2 publication Critical patent/HUP0000889A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
HU0000889A 1997-02-28 1998-02-16 Acarbose (acb) cluster from actinoplanes sp. se 50/110 HUP0000889A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19708127A DE19708127A1 (en) 1997-02-28 1997-02-28 Acarbose acb clusters: isolation of other genes of acarbose biosynthesis and acarbose metabolism from Actinoplanes sp. SE 50/110 and its use

Publications (1)

Publication Number Publication Date
HUP0000889A2 true HUP0000889A2 (en) 2000-07-28

Family

ID=7821816

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000889A HUP0000889A2 (en) 1997-02-28 1998-02-16 Acarbose (acb) cluster from actinoplanes sp. se 50/110

Country Status (15)

Country Link
EP (1) EP0968294A1 (en)
KR (1) KR20000075777A (en)
CN (1) CN1249001A (en)
AU (1) AU6296898A (en)
BG (1) BG103672A (en)
BR (1) BR9807640A (en)
CA (1) CA2282735A1 (en)
CZ (1) CZ9903054A3 (en)
DE (1) DE19708127A1 (en)
HU (1) HUP0000889A2 (en)
IL (1) IL131433A0 (en)
NO (1) NO994164D0 (en)
PL (1) PL335369A1 (en)
WO (1) WO1998038313A1 (en)
ZA (1) ZA981659B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796915A3 (en) * 1996-03-22 1999-04-14 Bayer Ag Process for the preparation and use of acarviosyl-transferase in the conversion of ascarbose-homologous in acarbose and in the preparation of acarbose-homologous
TW201217533A (en) * 2010-08-04 2012-05-01 Bayer Pharma AG Genomics of actinoplanes utahensis
CN106167814B (en) * 2016-08-31 2019-08-09 河北华荣制药有限公司 A method of improving acarbose fermentation unit
CN106566796B (en) * 2016-10-28 2020-11-10 上海交通大学 Genetic operation system of acarbose producing bacterium Actinoplanes spp
CN112592878B (en) * 2020-12-25 2022-08-26 上海交通大学 Method for enhancing expression of positive regulatory protein gene to improve acarbose fermentation level
CN113444670A (en) * 2021-07-28 2021-09-28 山东鲁抗医药股份有限公司 Screening method and culture method of high-activity acarbose producing strain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19507214A1 (en) * 1995-03-02 1996-10-31 Bayer Ag Acarbose biosynthesis genes from Actinoplanes sp., Process for their isolation and their use
DE19622783A1 (en) * 1996-06-07 1997-12-11 Hoechst Ag Isolation of the biosynthetic genes for pseudo-oligosaccharides from Streptomyces glaucescens GLA.O and their use

Also Published As

Publication number Publication date
BR9807640A (en) 2000-03-21
IL131433A0 (en) 2001-01-28
PL335369A1 (en) 2000-04-25
CZ9903054A3 (en) 1999-11-17
KR20000075777A (en) 2000-12-26
BG103672A (en) 2000-05-31
WO1998038313A1 (en) 1998-09-03
ZA981659B (en) 1998-09-10
NO994164L (en) 1999-08-27
EP0968294A1 (en) 2000-01-05
AU6296898A (en) 1998-09-18
DE19708127A1 (en) 1998-09-03
CN1249001A (en) 2000-03-29
NO994164D0 (en) 1999-08-27
CA2282735A1 (en) 1998-09-03

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