NZ751689A - Recombinant binding proteins and their use - Google Patents

Recombinant binding proteins and their use Download PDF

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Publication number
NZ751689A
NZ751689A NZ751689A NZ75168917A NZ751689A NZ 751689 A NZ751689 A NZ 751689A NZ 751689 A NZ751689 A NZ 751689A NZ 75168917 A NZ75168917 A NZ 75168917A NZ 751689 A NZ751689 A NZ 751689A
Authority
NZ
New Zealand
Prior art keywords
protein
seq
ankyrin repeat
binding protein
recombinant binding
Prior art date
Application number
NZ751689A
Other languages
English (en)
Inventor
Clara Metz
Ulrike Fiedler
Ignacio Dolado
Heike Maria Strobel
Original Assignee
Molecular Partners Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Partners Ag filed Critical Molecular Partners Ag
Publication of NZ751689A publication Critical patent/NZ751689A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ751689A 2016-09-22 2017-09-20 Recombinant binding proteins and their use NZ751689A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16190221 2016-09-22
PCT/EP2017/073768 WO2018054971A1 (en) 2016-09-22 2017-09-20 Recombinant binding proteins and their use

Publications (1)

Publication Number Publication Date
NZ751689A true NZ751689A (en) 2021-07-30

Family

ID=57046984

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ751689A NZ751689A (en) 2016-09-22 2017-09-20 Recombinant binding proteins and their use

Country Status (20)

Country Link
US (2) US10717772B2 (enExample)
EP (1) EP3515933B9 (enExample)
JP (1) JP6976335B2 (enExample)
KR (1) KR102270315B1 (enExample)
CN (1) CN109790206A (enExample)
AR (1) AR109680A1 (enExample)
AU (1) AU2017331329B2 (enExample)
BR (1) BR112019005587A2 (enExample)
CA (1) CA3036301C (enExample)
CL (1) CL2019000729A1 (enExample)
CO (1) CO2019002609A2 (enExample)
ES (1) ES2953516T3 (enExample)
IL (1) IL265489B (enExample)
MX (1) MX377424B (enExample)
MY (1) MY196882A (enExample)
NZ (1) NZ751689A (enExample)
PH (1) PH12019500596B1 (enExample)
SA (1) SA519401369B1 (enExample)
WO (1) WO2018054971A1 (enExample)
ZA (1) ZA201901592B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020286600A1 (en) * 2019-06-04 2021-12-23 Molecular Partners Ag Recombinant FAP binding proteins and their use
AU2020289080A1 (en) * 2019-06-04 2021-12-23 Molecular Partners Ag Multispecific proteins
EP3980452A1 (en) * 2019-06-04 2022-04-13 Molecular Partners AG Recombinant 4-1bb binding proteins and their use
CA3138805A1 (en) 2019-06-04 2020-12-10 Johannes Schilling Designed ankyrin repeat domain with improved stability
CN114929730A (zh) 2019-12-11 2022-08-19 分子合作伙伴股份公司 重组肽-mhc复合物结合蛋白及其生成和用途
MX2022013945A (es) * 2020-05-06 2023-02-14 Molecular Partners Ag Nuevas proteinas de union a repeticiones de anquirina y sus usos.
JP2023528204A (ja) 2020-05-14 2023-07-04 モレキュラー パートナーズ アクチェンゲゼルシャフト 多選択性タンパク質
US20240279309A1 (en) * 2020-05-14 2024-08-22 Molecular Partners Ag Recombinant cd40 binding proteins and their use
WO2022130300A1 (en) 2020-12-16 2022-06-23 Molecular Partners Ag Novel slow-release prodrugs
JP2024509904A (ja) 2021-03-09 2024-03-05 モレキュラー パートナーズ アクチェンゲゼルシャフト 新規なDARPinに基づく多重特異性T細胞エンゲージャ
US20240156980A1 (en) 2021-03-09 2024-05-16 Molecular Partners Ag Protease cleavable prodrugs
EP4304730A1 (en) 2021-03-09 2024-01-17 Molecular Partners AG Novel darpin based cd33 engagers
AU2022233791A1 (en) 2021-03-09 2023-09-28 Molecular Partners Ag Novel darpin based cd123 engagers
IL313411A (en) 2021-12-14 2024-08-01 Molecular Partners Ag Designed repeat domains with dual binding specificity and their use
CN119731200A (zh) 2022-08-01 2025-03-28 分子合作伙伴股份公司 经电荷修饰设计的重复结构域及其用途
WO2024038307A1 (en) 2022-08-19 2024-02-22 Novartis Ag Dosing regimens for sars-cov-2 binding molecules
EP4665755A1 (en) 2023-02-17 2025-12-24 Ablynx N.V. Polypeptides binding to the neonatal fc receptor
WO2024179981A1 (en) 2023-02-27 2024-09-06 Molecular Partners Ag Darpins for use in reducing renal accumulation of drugs
WO2024251628A1 (en) 2023-06-06 2024-12-12 Molecular Partners Ag Recombinant cd16a binding proteins and their use
CN121263440A (zh) 2023-06-06 2026-01-02 分子合作伙伴股份公司 重组cd2结合蛋白及其用途
WO2025146487A1 (en) 2024-01-05 2025-07-10 Molecular Partners Ag Multispecific binding proteins
WO2025146491A1 (en) 2024-01-05 2025-07-10 Molecular Partners Ag Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
WO2025163144A1 (en) 2024-01-31 2025-08-07 Molecular Partners Ag Recombinant mesothelin binding proteins and their use
WO2025181039A1 (en) 2024-03-01 2025-09-04 Molecular Partners Ag Therapeutic combinations comprising a multi-specific t cell engager
WO2026013280A1 (en) * 2024-07-11 2026-01-15 Johann Wolfgang Goethe-Universität Frankfurt am Main Designed ankyrin repeat proteins binding p53, and uses thereof

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SE509359C2 (sv) 1989-08-01 1999-01-18 Cemu Bioteknik Ab Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
US7371376B1 (en) 1996-10-18 2008-05-13 Genentech, Inc. Anti-ErbB2 antibodies
CA2421447C (en) 2000-09-08 2012-05-08 Universitat Zurich Collections of repeat proteins comprising repeat modules
PT1567641E (pt) * 2001-08-24 2012-08-21 Uvic Industry Partnerships Inc Proaerolisina contendo sequência de activação de proteases e métodos de uso para o tratamento do cancro da próstata
CN101875919A (zh) 2004-11-12 2010-11-03 拜耳先灵医药股份有限公司 重组新城疫病毒
RU2412249C2 (ru) 2005-07-08 2011-02-20 Юниверсити Оф Цюрих Фаговый дисплей с применением котрансляционной транслокации слитых полипептидов
CA2700391A1 (en) 2007-09-24 2009-04-02 University Of Zuerich Designed armadillo repeat proteins
CN101970490A (zh) 2007-11-27 2011-02-09 埃博灵克斯股份有限公司 针对异二聚体细胞因子和/或其受体的氨基酸序列以及包括所述氨基酸序列的多肽
EP2358746B1 (en) 2008-11-03 2020-09-16 Molecular Partners AG Binding proteins inhibiting the vegf-a receptor interaction
TWI510246B (zh) 2010-04-30 2015-12-01 Molecular Partners Ag 抑制vegf-a受體交互作用的經修飾結合性蛋白質
EP2643349B1 (en) * 2010-11-26 2019-09-04 Molecular Partners AG Designed repeat proteins binding to serum albumin
KR20140039203A (ko) 2011-04-29 2014-04-01 얀센 바이오테크 인코포레이티드 Il4/il13 결합 반복 단백질 및 용도
WO2014001442A1 (en) 2012-06-28 2014-01-03 Molecular Partners Ag Designed ankyrin repeat proteins binding to platelet-derived growth factor
JP2015532306A (ja) * 2012-10-15 2015-11-09 チューリッヒ大学 癌治療のための二重特異性her2リガンド
EP2738180A1 (en) 2012-11-30 2014-06-04 Molecular Partners AG Binding proteins comprising at least two binding domains against HER2.
US11453708B2 (en) 2013-05-31 2022-09-27 Molecular Partners Ag Designed ankyrin repeat proteins binding to hepatocyte growth factor
US9458211B1 (en) * 2015-04-02 2016-10-04 Molecular Partners Ag Recombinant proteins that simultaneously bind HGF, VEGF-A and serum albumin, comprising ankyrin repeat domains

Also Published As

Publication number Publication date
EP3515933B1 (en) 2023-06-07
US20180155402A1 (en) 2018-06-07
CA3036301A1 (en) 2018-03-29
PH12019500596A1 (en) 2019-07-29
AU2017331329B2 (en) 2020-10-29
CO2019002609A2 (es) 2019-05-31
SA519401369B1 (ar) 2022-12-22
EP3515933C0 (en) 2023-06-07
AR109680A1 (es) 2019-01-09
BR112019005587A2 (pt) 2019-06-11
KR102270315B1 (ko) 2021-06-29
ZA201901592B (en) 2021-04-28
IL265489A (en) 2019-05-30
CA3036301C (en) 2021-04-20
RU2019111628A (ru) 2020-10-19
MY196882A (en) 2023-05-08
EP3515933A1 (en) 2019-07-31
WO2018054971A1 (en) 2018-03-29
CL2019000729A1 (es) 2019-06-14
EP3515933B9 (en) 2023-08-16
JP6976335B2 (ja) 2021-12-08
IL265489B (en) 2021-07-29
PH12019500596B1 (en) 2024-02-21
US20210130420A1 (en) 2021-05-06
AU2017331329A1 (en) 2019-04-04
JP2019531093A (ja) 2019-10-31
KR20190050802A (ko) 2019-05-13
RU2019111628A3 (enExample) 2020-10-30
ES2953516T3 (es) 2023-11-14
MX377424B (es) 2025-03-10
MX2019003298A (es) 2019-09-26
US10717772B2 (en) 2020-07-21
CN109790206A (zh) 2019-05-21

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PSEA Patent sealed
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Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 20 SEP 2023 BY DENNEMEYER + CO. S.A.R.L.

Effective date: 20220913

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 20 SEP 2024 BY DENNEMEYER + CO. S.A.R.L.

Effective date: 20230911

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