AR109680A1 - Proteínas recombinantes y sus usos - Google Patents
Proteínas recombinantes y sus usosInfo
- Publication number
- AR109680A1 AR109680A1 ARP170102593A ARP170102593A AR109680A1 AR 109680 A1 AR109680 A1 AR 109680A1 AR P170102593 A ARP170102593 A AR P170102593A AR P170102593 A ARP170102593 A AR P170102593A AR 109680 A1 AR109680 A1 AR 109680A1
- Authority
- AR
- Argentina
- Prior art keywords
- recombinant binding
- amino acid
- acid sequence
- nucleic acids
- binding protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Ácidos nucleicos que codifican dichas proteínas de unión recombinantes, composiciones farmacéuticas que comprenden dichas proteínas de unión recombinantes o ácidos nucleicos y el uso de dichas proteínas de unión recombinantes, ácidos nucleicos o composiciones farmacéuticas en el tratamiento de cáncer. Reivindicación 1: Una proteína de unión recombinante que comprende una secuencia de aminoácidos que tiene al menos un 88% de identidad de secuencia de aminoácidos con la proteína de unión recombinante que consiste en la SEQ ID Nº 21, en donde dicha proteína de unión recombinante comprende dos dominios diseñados con repeticiones de anquirina con especificidad de unión para seroalbúmina comprendiendo cada uno la secuencia de aminoácidos de SEQ ID Nº 14.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16190221 | 2016-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR109680A1 true AR109680A1 (es) | 2019-01-09 |
Family
ID=57046984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170102593A AR109680A1 (es) | 2016-09-22 | 2017-09-20 | Proteínas recombinantes y sus usos |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10717772B2 (es) |
| EP (1) | EP3515933B9 (es) |
| JP (1) | JP6976335B2 (es) |
| KR (1) | KR102270315B1 (es) |
| CN (1) | CN109790206A (es) |
| AR (1) | AR109680A1 (es) |
| AU (1) | AU2017331329B2 (es) |
| BR (1) | BR112019005587A2 (es) |
| CA (1) | CA3036301C (es) |
| CL (1) | CL2019000729A1 (es) |
| CO (1) | CO2019002609A2 (es) |
| ES (1) | ES2953516T3 (es) |
| IL (1) | IL265489B (es) |
| MX (1) | MX2019003298A (es) |
| MY (1) | MY196882A (es) |
| NZ (1) | NZ751689A (es) |
| PH (1) | PH12019500596A1 (es) |
| SA (1) | SA519401369B1 (es) |
| WO (1) | WO2018054971A1 (es) |
| ZA (1) | ZA201901592B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3139051A1 (en) * | 2019-06-04 | 2020-12-10 | Christian REICHEN | Multispecific proteins |
| CA3139041A1 (en) * | 2019-06-04 | 2020-12-10 | Christian REICHEN | Recombinant 4-1bb binding proteins and their use |
| AU2020286600A1 (en) * | 2019-06-04 | 2021-12-23 | Molecular Partners Ag | Recombinant FAP binding proteins and their use |
| BR112021024237A2 (pt) | 2019-06-04 | 2022-04-19 | Molecular Partners Ag | Domínio de repetição de anquirina projetado com estabilidade aprimorada |
| AU2020399230A1 (en) | 2019-12-11 | 2022-06-23 | Molecular Partners Ag | Recombinant peptide-MHC complex binding proteins and their generation and use |
| IL297940A (en) | 2020-05-06 | 2023-01-01 | Molecular Partners Ag | New ankyrin repeat binding proteins and their uses |
| WO2021229076A1 (en) * | 2020-05-14 | 2021-11-18 | Molecular Partners Ag | Recombinant cd40 binding proteins and their use |
| AU2021271129A1 (en) | 2020-05-14 | 2022-12-15 | Molecular Partners Ag | Multispecific proteins |
| WO2022130300A1 (en) | 2020-12-16 | 2022-06-23 | Molecular Partners Ag | Novel slow-release prodrugs |
| CA3211248A1 (en) | 2021-03-09 | 2022-09-15 | Nina RESCHKE | Novel darpin based cd33 engagers |
| EP4305063A1 (en) | 2021-03-09 | 2024-01-17 | Molecular Partners AG | Protease cleavable prodrugs |
| KR20230155464A (ko) | 2021-03-09 | 2023-11-10 | 몰리큘라 파트너스 아게 | 신규한 DARPin-기반 다중특이성 T-세포 인게이저 |
| AU2022233791A1 (en) | 2021-03-09 | 2023-09-28 | Molecular Partners Ag | Novel darpin based cd123 engagers |
| CA3239407A1 (en) | 2021-12-14 | 2023-06-22 | Simon FONTAINE | Designed repeat domains with dual binding specificity and their use |
| WO2024028278A1 (en) | 2022-08-01 | 2024-02-08 | Molecular Partners Ag | Charge modified designed repeat domains and their use |
| WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
| WO2024170756A1 (en) | 2023-02-17 | 2024-08-22 | Ablynx N.V. | Polypeptides binding to the neonatal fc receptor |
| WO2024179981A1 (en) | 2023-02-27 | 2024-09-06 | Molecular Partners Ag | Darpins for use in reducing renal accumulation of drugs |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US7371376B1 (en) | 1996-10-18 | 2008-05-13 | Genentech, Inc. | Anti-ErbB2 antibodies |
| ES2335861T3 (es) | 2000-09-08 | 2010-04-06 | Universitat Zurich | Grupos de proteinas repetitivas que comprenden modulos repetitivos. |
| WO2003018611A2 (en) * | 2001-08-24 | 2003-03-06 | University Of Victoria Innovation And Development Corporation | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
| KR20070085314A (ko) | 2004-11-12 | 2007-08-27 | 바이엘 쉐링 파마 악티엔게젤샤프트 | 재조합 뉴캐슬 질환 바이러스 |
| JP5042218B2 (ja) | 2005-07-08 | 2012-10-03 | ユニバーシティ・オブ・チューリッヒ | 融合ポリペプチドの翻訳と同時のトランスロケーションを使用するファージディスプレイ |
| EP2198022B1 (en) | 2007-09-24 | 2024-03-06 | University Of Zurich | Designed armadillo repeat proteins |
| JP2011504740A (ja) | 2007-11-27 | 2011-02-17 | アブリンクス エン．ヴェー． | ヘテロ二量体サイトカイン及び／又はこれらの受容体に指向性を有するアミノ酸配列、並びにこれを含むポリペプチド |
| CN102272148A (zh) | 2008-11-03 | 2011-12-07 | 分子组合公司 | 抑制vegf-a受体相互作用的结合蛋白 |
| TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質 |
| JP6105479B2 (ja) * | 2010-11-26 | 2017-03-29 | モレキュラー・パートナーズ・アーゲーＭｏｌｅｃｕｌａｒ Ｐａｒｔｎｅｒｓ Ａｇ | 血清アルブミンに結合する設計リピートタンパク質 |
| BR112013027766A2 (pt) | 2011-04-29 | 2016-11-29 | Janssen Biotech Inc | proteinas de repetição de ligação de il4/il13 e usos |
| US9163070B2 (en) | 2012-06-28 | 2015-10-20 | Molecular Partners Ag | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
| WO2014060365A1 (en) | 2012-10-15 | 2014-04-24 | Universität Zürich Prorektorat Mnw | Bispecific her2 ligands for cancer therapy |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| JP6486908B2 (ja) | 2013-05-31 | 2019-03-20 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 肝細胞増殖因子に結合する設計アンキリン反復タンパク質 |
| CN107454904A (zh) | 2015-04-02 | 2017-12-08 | 分子组合公司 | 对血清白蛋白具有结合特异性的经设计的锚蛋白重复结构域 |
-
2017
- 2017-09-20 AR ARP170102593A patent/AR109680A1/es unknown
- 2017-09-20 EP EP17778226.5A patent/EP3515933B9/en active Active
- 2017-09-20 MY MYPI2019001523A patent/MY196882A/en unknown
- 2017-09-20 ES ES17778226T patent/ES2953516T3/es active Active
- 2017-09-20 JP JP2019536693A patent/JP6976335B2/ja active Active
- 2017-09-20 CA CA3036301A patent/CA3036301C/en active Active
- 2017-09-20 CN CN201780058511.0A patent/CN109790206A/zh active Pending
- 2017-09-20 NZ NZ751689A patent/NZ751689A/en unknown
- 2017-09-20 BR BR112019005587A patent/BR112019005587A2/pt not_active Application Discontinuation
- 2017-09-20 KR KR1020197009396A patent/KR102270315B1/ko active IP Right Grant
- 2017-09-20 MX MX2019003298A patent/MX2019003298A/es active IP Right Grant
- 2017-09-20 WO PCT/EP2017/073768 patent/WO2018054971A1/en unknown
- 2017-09-20 US US15/710,001 patent/US10717772B2/en active Active
- 2017-09-20 AU AU2017331329A patent/AU2017331329B2/en active Active
-
2019
- 2019-03-14 ZA ZA2019/01592A patent/ZA201901592B/en unknown
- 2019-03-19 IL IL265489A patent/IL265489B/en unknown
- 2019-03-19 PH PH12019500596A patent/PH12019500596A1/en unknown
- 2019-03-20 SA SA519401369A patent/SA519401369B1/ar unknown
- 2019-03-21 CO CONC2019/0002609A patent/CO2019002609A2/es unknown
- 2019-03-21 CL CL2019000729A patent/CL2019000729A1/es unknown
-
2020
- 2020-06-22 US US16/907,415 patent/US20210130420A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3515933B9 (en) | 2023-08-16 |
| BR112019005587A2 (pt) | 2019-06-11 |
| AU2017331329B2 (en) | 2020-10-29 |
| US20210130420A1 (en) | 2021-05-06 |
| JP6976335B2 (ja) | 2021-12-08 |
| IL265489B (en) | 2021-07-29 |
| CN109790206A (zh) | 2019-05-21 |
| CA3036301C (en) | 2021-04-20 |
| EP3515933A1 (en) | 2019-07-31 |
| NZ751689A (en) | 2021-07-30 |
| RU2019111628A3 (es) | 2020-10-30 |
| PH12019500596A1 (en) | 2019-07-29 |
| AU2017331329A1 (en) | 2019-04-04 |
| KR102270315B1 (ko) | 2021-06-29 |
| JP2019531093A (ja) | 2019-10-31 |
| CO2019002609A2 (es) | 2019-05-31 |
| CA3036301A1 (en) | 2018-03-29 |
| IL265489A (en) | 2019-05-30 |
| KR20190050802A (ko) | 2019-05-13 |
| RU2019111628A (ru) | 2020-10-19 |
| MX2019003298A (es) | 2019-09-26 |
| CL2019000729A1 (es) | 2019-06-14 |
| EP3515933B1 (en) | 2023-06-07 |
| US20180155402A1 (en) | 2018-06-07 |
| SA519401369B1 (ar) | 2022-12-22 |
| ES2953516T3 (es) | 2023-11-14 |
| EP3515933C0 (en) | 2023-06-07 |
| US10717772B2 (en) | 2020-07-21 |
| ZA201901592B (en) | 2021-04-28 |
| MY196882A (en) | 2023-05-08 |
| WO2018054971A1 (en) | 2018-03-29 |
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