CL2019000729A1 - Proteínas de unión recombinantes y sus usos. - Google Patents
Proteínas de unión recombinantes y sus usos.Info
- Publication number
- CL2019000729A1 CL2019000729A1 CL2019000729A CL2019000729A CL2019000729A1 CL 2019000729 A1 CL2019000729 A1 CL 2019000729A1 CL 2019000729 A CL2019000729 A CL 2019000729A CL 2019000729 A CL2019000729 A CL 2019000729A CL 2019000729 A1 CL2019000729 A1 CL 2019000729A1
- Authority
- CL
- Chile
- Prior art keywords
- union
- recombinating
- associdus
- proteins
- binding proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE DESVELAN NUEVAS PROTEÍNAS DE UNIÓN RECOMBINANTES, QUE COMPRENDEN DOMINIOS DISEÑADOS CON REPETICIONES DE ANQUIRINA CON ESPECIFICIDAD DE UNIÓN PARA EL HER2, Y QUE COMPRENDEN DOMINIOS DISEÑADOS CON REPETICIONES DE ANQUIRINA CON ESPECIFICIDAD DE UNIÓN PARA LA SEROALBÚMINA, ASÍ COMO LOS ÁCIDOS NUCLEICOS QUE CODIFICAN DICHAS PROTEÍNAS DE UNIÓN RECOMBINANTES, COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN DICHAS PROTEÍNAS DE UNIÓN RECOMBINANTES O ÁCIDOS NUCLEICOS Y EL USO DE DICHAS PROTEÍNAS DE UNIÓN RECOMBINANTES, ÁCIDOS NUCLEICOS O COMPOSICIONES FARMACÉUTICAS EN EL TRATAMIENTO DE ENFERMEDADES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16190221 | 2016-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019000729A1 true CL2019000729A1 (es) | 2019-06-14 |
Family
ID=57046984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019000729A CL2019000729A1 (es) | 2016-09-22 | 2019-03-21 | Proteínas de unión recombinantes y sus usos. |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10717772B2 (es) |
| EP (1) | EP3515933B9 (es) |
| JP (1) | JP6976335B2 (es) |
| KR (1) | KR102270315B1 (es) |
| CN (1) | CN109790206A (es) |
| AR (1) | AR109680A1 (es) |
| AU (1) | AU2017331329B2 (es) |
| BR (1) | BR112019005587A2 (es) |
| CA (1) | CA3036301C (es) |
| CL (1) | CL2019000729A1 (es) |
| CO (1) | CO2019002609A2 (es) |
| ES (1) | ES2953516T3 (es) |
| IL (1) | IL265489B (es) |
| MX (1) | MX2019003298A (es) |
| MY (1) | MY196882A (es) |
| NZ (1) | NZ751689A (es) |
| PH (1) | PH12019500596A1 (es) |
| SA (1) | SA519401369B1 (es) |
| WO (1) | WO2018054971A1 (es) |
| ZA (1) | ZA201901592B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022535564A (ja) | 2019-06-04 | 2022-08-09 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 多選択性タンパク質 |
| JP2022535106A (ja) | 2019-06-04 | 2022-08-04 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 改善された安定性を有する設計されたアンキリン反復ドメイン |
| KR20220016942A (ko) * | 2019-06-04 | 2022-02-10 | 몰리큘라 파트너스 아게 | 재조합 fap 결합 단백질 및 이의 용도 |
| MX2022007120A (es) | 2019-12-11 | 2022-09-09 | Molecular Partners Ag | Proteínas de unión al complejo péptido-mhc recombinantes y su generación y uso. |
| JP2023525518A (ja) | 2020-05-06 | 2023-06-16 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 新規アンキリンリピート結合タンパク質とその用途 |
| KR20230022176A (ko) | 2020-05-14 | 2023-02-14 | 몰리큘라 파트너스 아게 | 다중특이적 단백질 |
| EP4149960A1 (en) * | 2020-05-14 | 2023-03-22 | Molecular Partners AG | Recombinant cd40 binding proteins and their use |
| CA3202358A1 (en) | 2020-12-16 | 2022-06-23 | Andreas BOSSHART | Novel slow-release prodrugs |
| AU2022233791A1 (en) | 2021-03-09 | 2023-09-28 | Molecular Partners Ag | Novel darpin based cd123 engagers |
| EP4305063A1 (en) | 2021-03-09 | 2024-01-17 | Molecular Partners AG | Protease cleavable prodrugs |
| EP4304731A1 (en) | 2021-03-09 | 2024-01-17 | Molecular Partners AG | Novel darpin based multi-specific t-cell engagers |
| JP2024508969A (ja) | 2021-03-09 | 2024-02-28 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 新規のＤＡＲＰｉｎに基づくＣＤ３３エンゲージャ |
| AU2022413461A1 (en) | 2021-12-14 | 2024-06-06 | Molecular Partners Ag | Designed repeat domains with dual binding specificity and their use |
| WO2024028278A1 (en) | 2022-08-01 | 2024-02-08 | Molecular Partners Ag | Charge modified designed repeat domains and their use |
| WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US7371376B1 (en) | 1996-10-18 | 2008-05-13 | Genentech, Inc. | Anti-ErbB2 antibodies |
| CA2421447C (en) | 2000-09-08 | 2012-05-08 | Universitat Zurich | Collections of repeat proteins comprising repeat modules |
| AU2002331720B2 (en) * | 2001-08-24 | 2007-10-11 | Johns Hopkins University | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
| CN101056646A (zh) | 2004-11-12 | 2007-10-17 | 拜耳先灵医药股份有限公司 | 重组新城疫病毒 |
| DK1902131T3 (da) | 2005-07-08 | 2010-03-01 | Univ Zuerich | Fag-display under anvendelse af cotranslational translokation af fusionspolypeptider |
| US9365629B2 (en) | 2007-09-24 | 2016-06-14 | University Of Zurich | Designed armadillo repeat proteins |
| CN101970490A (zh) | 2007-11-27 | 2011-02-09 | 埃博灵克斯股份有限公司 | 针对异二聚体细胞因子和/或其受体的氨基酸序列以及包括所述氨基酸序列的多肽 |
| NZ592591A (en) | 2008-11-03 | 2012-04-27 | Molecular Partners Ag | Binding proteins comprising ankyrin repeast domains that inhibit the vegf-a receptor interaction |
| AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
| JP6173216B2 (ja) * | 2010-11-26 | 2017-08-02 | モレキュラー・パートナーズ・アーゲーＭｏｌｅｃｕｌａｒ Ｐａｒｔｎｅｒｓ Ａｇ | 設計アンキリンリピートタンパク質のための改善されたキャッピングモジュール |
| KR20140039203A (ko) | 2011-04-29 | 2014-04-01 | 얀센 바이오테크 인코포레이티드 | Il4/il13 결합 반복 단백질 및 용도 |
| CN104508129A (zh) | 2012-06-28 | 2015-04-08 | 分子伴侣公司 | 设计的与血小板衍生生长因子结合的锚蛋白重复序列蛋白 |
| WO2014060365A1 (en) * | 2012-10-15 | 2014-04-24 | Universität Zürich Prorektorat Mnw | Bispecific her2 ligands for cancer therapy |
| EP2738180A1 (en) * | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| JP6486908B2 (ja) | 2013-05-31 | 2019-03-20 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 肝細胞増殖因子に結合する設計アンキリン反復タンパク質 |
| SG11201707606RA (en) * | 2015-04-02 | 2017-10-30 | Molecular Partners Ag | Designed ankyrin repeat domains with binding specificity for serum albumin |
-
2017
- 2017-09-20 WO PCT/EP2017/073768 patent/WO2018054971A1/en unknown
- 2017-09-20 US US15/710,001 patent/US10717772B2/en active Active
- 2017-09-20 MX MX2019003298A patent/MX2019003298A/es active IP Right Grant
- 2017-09-20 EP EP17778226.5A patent/EP3515933B9/en active Active
- 2017-09-20 CN CN201780058511.0A patent/CN109790206A/zh active Pending
- 2017-09-20 MY MYPI2019001523A patent/MY196882A/en unknown
- 2017-09-20 AU AU2017331329A patent/AU2017331329B2/en active Active
- 2017-09-20 JP JP2019536693A patent/JP6976335B2/ja active Active
- 2017-09-20 KR KR1020197009396A patent/KR102270315B1/ko active IP Right Grant
- 2017-09-20 BR BR112019005587A patent/BR112019005587A2/pt unknown
- 2017-09-20 CA CA3036301A patent/CA3036301C/en active Active
- 2017-09-20 AR ARP170102593A patent/AR109680A1/es unknown
- 2017-09-20 NZ NZ751689A patent/NZ751689A/en unknown
- 2017-09-20 ES ES17778226T patent/ES2953516T3/es active Active
-
2019
- 2019-03-14 ZA ZA2019/01592A patent/ZA201901592B/en unknown
- 2019-03-19 IL IL265489A patent/IL265489B/en unknown
- 2019-03-19 PH PH12019500596A patent/PH12019500596A1/en unknown
- 2019-03-20 SA SA519401369A patent/SA519401369B1/ar unknown
- 2019-03-21 CL CL2019000729A patent/CL2019000729A1/es unknown
- 2019-03-21 CO CONC2019/0002609A patent/CO2019002609A2/es unknown
-
2020
- 2020-06-22 US US16/907,415 patent/US20210130420A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017331329B2 (en) | 2020-10-29 |
| MY196882A (en) | 2023-05-08 |
| MX2019003298A (es) | 2019-09-26 |
| US10717772B2 (en) | 2020-07-21 |
| EP3515933C0 (en) | 2023-06-07 |
| ES2953516T3 (es) | 2023-11-14 |
| IL265489A (en) | 2019-05-30 |
| JP2019531093A (ja) | 2019-10-31 |
| IL265489B (en) | 2021-07-29 |
| RU2019111628A (ru) | 2020-10-19 |
| EP3515933A1 (en) | 2019-07-31 |
| AR109680A1 (es) | 2019-01-09 |
| EP3515933B1 (en) | 2023-06-07 |
| NZ751689A (en) | 2021-07-30 |
| CN109790206A (zh) | 2019-05-21 |
| CA3036301A1 (en) | 2018-03-29 |
| CA3036301C (en) | 2021-04-20 |
| US20210130420A1 (en) | 2021-05-06 |
| JP6976335B2 (ja) | 2021-12-08 |
| EP3515933B9 (en) | 2023-08-16 |
| CO2019002609A2 (es) | 2019-05-31 |
| KR102270315B1 (ko) | 2021-06-29 |
| PH12019500596A1 (en) | 2019-07-29 |
| SA519401369B1 (ar) | 2022-12-22 |
| AU2017331329A1 (en) | 2019-04-04 |
| RU2019111628A3 (es) | 2020-10-30 |
| BR112019005587A2 (pt) | 2019-06-11 |
| KR20190050802A (ko) | 2019-05-13 |
| WO2018054971A1 (en) | 2018-03-29 |
| US20180155402A1 (en) | 2018-06-07 |
| ZA201901592B (en) | 2021-04-28 |
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