AU2017331329B2 - Recombinant binding proteins and their use - Google Patents
Recombinant binding proteins and their use Download PDFInfo
- Publication number
- AU2017331329B2 AU2017331329B2 AU2017331329A AU2017331329A AU2017331329B2 AU 2017331329 B2 AU2017331329 B2 AU 2017331329B2 AU 2017331329 A AU2017331329 A AU 2017331329A AU 2017331329 A AU2017331329 A AU 2017331329A AU 2017331329 B2 AU2017331329 B2 AU 2017331329B2
- Authority
- AU
- Australia
- Prior art keywords
- ala
- leu
- gly
- asp
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16190221 | 2016-09-22 | ||
| EP16190221.8 | 2016-09-22 | ||
| PCT/EP2017/073768 WO2018054971A1 (en) | 2016-09-22 | 2017-09-20 | Recombinant binding proteins and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2017331329A1 AU2017331329A1 (en) | 2019-04-04 |
| AU2017331329B2 true AU2017331329B2 (en) | 2020-10-29 |
Family
ID=57046984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2017331329A Ceased AU2017331329B2 (en) | 2016-09-22 | 2017-09-20 | Recombinant binding proteins and their use |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US10717772B2 (enExample) |
| EP (1) | EP3515933B9 (enExample) |
| JP (1) | JP6976335B2 (enExample) |
| KR (1) | KR102270315B1 (enExample) |
| CN (1) | CN109790206A (enExample) |
| AR (1) | AR109680A1 (enExample) |
| AU (1) | AU2017331329B2 (enExample) |
| BR (1) | BR112019005587A2 (enExample) |
| CA (1) | CA3036301C (enExample) |
| CL (1) | CL2019000729A1 (enExample) |
| CO (1) | CO2019002609A2 (enExample) |
| ES (1) | ES2953516T3 (enExample) |
| IL (1) | IL265489B (enExample) |
| MX (1) | MX377424B (enExample) |
| MY (1) | MY196882A (enExample) |
| NZ (1) | NZ751689A (enExample) |
| PH (1) | PH12019500596B1 (enExample) |
| SA (1) | SA519401369B1 (enExample) |
| WO (1) | WO2018054971A1 (enExample) |
| ZA (1) | ZA201901592B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020286715A1 (en) * | 2019-06-04 | 2021-12-23 | Molecular Partners Ag | Recombinant 4-1 BB binding proteins and their use |
| WO2020245746A1 (en) * | 2019-06-04 | 2020-12-10 | Molecular Partners Ag | Multispecific proteins |
| CA3139164A1 (en) * | 2019-06-04 | 2020-12-10 | Molecular Partners Ag | Recombinant fap binding proteins and their use |
| WO2020245171A1 (en) | 2019-06-04 | 2020-12-10 | Molecular Partners Ag | Designed ankyrin repeat domain with improved stability |
| CN114929730A (zh) | 2019-12-11 | 2022-08-19 | 分子合作伙伴股份公司 | 重组肽-mhc复合物结合蛋白及其生成和用途 |
| JP2023525518A (ja) | 2020-05-06 | 2023-06-16 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 新規アンキリンリピート結合タンパク質とその用途 |
| CN115996945A (zh) * | 2020-05-14 | 2023-04-21 | 分子合作伙伴股份公司 | 重组cd40结合蛋白及其用途 |
| WO2021229067A1 (en) | 2020-05-14 | 2021-11-18 | Molecular Partners Ag | Multispecific proteins |
| US20240108746A1 (en) | 2020-12-16 | 2024-04-04 | Molecular Partners Ag | Novel slow-release prodrugs |
| JP2024509890A (ja) | 2021-03-09 | 2024-03-05 | モレキュラー パートナーズ アクチェンゲゼルシャフト | プロテアーゼ切断可能なプロドラッグ |
| MX2023010543A (es) | 2021-03-09 | 2023-10-13 | Molecular Partners Ag | Ligadores multiespecificos de celulas t novedosos basados en darpin. |
| WO2022190018A1 (en) | 2021-03-09 | 2022-09-15 | Molecular Partners Ag | Novel darpin based cd123 engagers |
| CA3211248A1 (en) | 2021-03-09 | 2022-09-15 | Nina RESCHKE | Novel darpin based cd33 engagers |
| AU2022413461A1 (en) | 2021-12-14 | 2024-06-06 | Molecular Partners Ag | Designed repeat domains with dual binding specificity and their use |
| US20240228545A9 (en) | 2022-08-01 | 2024-07-11 | Molecular Partners Ag | Charge modified designed repeat domains and their use |
| WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
| KR20250151445A (ko) | 2023-02-17 | 2025-10-21 | 아블린쓰 엔.브이. | 신생아 fc 수용체에 결합하는 폴리펩티드 |
| WO2024179981A1 (en) | 2023-02-27 | 2024-09-06 | Molecular Partners Ag | Darpins for use in reducing renal accumulation of drugs |
| WO2024251742A1 (en) | 2023-06-06 | 2024-12-12 | Molecular Partners Ag | Recombinant cd2 binding proteins and their use |
| WO2024251628A1 (en) | 2023-06-06 | 2024-12-12 | Molecular Partners Ag | Recombinant cd16a binding proteins and their use |
| WO2025146491A1 (en) | 2024-01-05 | 2025-07-10 | Molecular Partners Ag | Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent |
| WO2025146487A1 (en) | 2024-01-05 | 2025-07-10 | Molecular Partners Ag | Multispecific binding proteins |
| WO2025163144A1 (en) | 2024-01-31 | 2025-08-07 | Molecular Partners Ag | Recombinant mesothelin binding proteins and their use |
| WO2025181039A1 (en) | 2024-03-01 | 2025-09-04 | Molecular Partners Ag | Therapeutic combinations comprising a multi-specific t cell engager |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016156596A1 (en) * | 2015-04-02 | 2016-10-06 | Molecular Partners Ag | Designed ankyrin repeat domains with binding specificity for serum albumin |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US7371376B1 (en) | 1996-10-18 | 2008-05-13 | Genentech, Inc. | Anti-ErbB2 antibodies |
| AU2002218166A1 (en) | 2000-09-08 | 2002-03-22 | Universitat Zurich | Collections of repeat proteins comprising repeat modules |
| CN100488981C (zh) * | 2001-08-24 | 2009-05-20 | 维多利亚大学创新和发展公司 | 含有蛋白酶激活序列的气单胞菌溶素原及其应用 |
| AU2005303912B2 (en) | 2004-11-12 | 2011-02-17 | Bayer Schering Pharma Aktiengesellschaft | Recombinant Newcastle Disease Virus |
| WO2007006665A1 (en) | 2005-07-08 | 2007-01-18 | University Of Zürich | Phage display using cotranslational translocation of fusion polypeptides |
| WO2009040338A1 (en) | 2007-09-24 | 2009-04-02 | University Of Zürich | Designed armadillo repeat proteins |
| US20110189203A1 (en) | 2007-11-27 | 2011-08-04 | Ablynx N.V. | Immunoglobulin constructs |
| MX359570B (es) | 2008-11-03 | 2018-10-01 | Molecular Partners Ag | Proteinas de union que inhiben la interaccion en el receptor de vegf-a. |
| TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質 |
| EP2643348B1 (en) * | 2010-11-26 | 2025-02-12 | Molecular Partners AG | Improved capping modules for designed ankyrin repeat proteins |
| JP2014519808A (ja) | 2011-04-29 | 2014-08-21 | ヤンセン バイオテツク，インコーポレーテツド | Ｉｌ４／ｉｌ１３に結合する反復タンパク質及び使用 |
| AU2013283296A1 (en) | 2012-06-28 | 2015-02-05 | Molecular Partners Ag | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
| AU2013331763B2 (en) | 2012-10-15 | 2018-02-15 | Universitat Zurich | Bispecific HER2 ligands for cancer therapy |
| EP2738180A1 (en) * | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| JP6486908B2 (ja) | 2013-05-31 | 2019-03-20 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 肝細胞増殖因子に結合する設計アンキリン反復タンパク質 |
-
2017
- 2017-09-20 NZ NZ751689A patent/NZ751689A/en not_active IP Right Cessation
- 2017-09-20 CA CA3036301A patent/CA3036301C/en active Active
- 2017-09-20 JP JP2019536693A patent/JP6976335B2/ja not_active Expired - Fee Related
- 2017-09-20 CN CN201780058511.0A patent/CN109790206A/zh active Pending
- 2017-09-20 PH PH1/2019/500596A patent/PH12019500596B1/en unknown
- 2017-09-20 MY MYPI2019001523A patent/MY196882A/en unknown
- 2017-09-20 MX MX2019003298A patent/MX377424B/es active IP Right Grant
- 2017-09-20 EP EP17778226.5A patent/EP3515933B9/en active Active
- 2017-09-20 WO PCT/EP2017/073768 patent/WO2018054971A1/en not_active Ceased
- 2017-09-20 AR ARP170102593A patent/AR109680A1/es not_active Application Discontinuation
- 2017-09-20 BR BR112019005587A patent/BR112019005587A2/pt not_active Application Discontinuation
- 2017-09-20 ES ES17778226T patent/ES2953516T3/es active Active
- 2017-09-20 US US15/710,001 patent/US10717772B2/en active Active
- 2017-09-20 AU AU2017331329A patent/AU2017331329B2/en not_active Ceased
- 2017-09-20 KR KR1020197009396A patent/KR102270315B1/ko not_active Expired - Fee Related
-
2019
- 2019-03-14 ZA ZA2019/01592A patent/ZA201901592B/en unknown
- 2019-03-19 IL IL265489A patent/IL265489B/en unknown
- 2019-03-20 SA SA519401369A patent/SA519401369B1/ar unknown
- 2019-03-21 CL CL2019000729A patent/CL2019000729A1/es unknown
- 2019-03-21 CO CONC2019/0002609A patent/CO2019002609A2/es unknown
-
2020
- 2020-06-22 US US16/907,415 patent/US20210130420A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016156596A1 (en) * | 2015-04-02 | 2016-10-06 | Molecular Partners Ag | Designed ankyrin repeat domains with binding specificity for serum albumin |
Also Published As
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| Publication | Publication Date | Title |
|---|---|---|
| AU2017331329B2 (en) | Recombinant binding proteins and their use | |
| AU2021286418B2 (en) | Designed ankyrin repeat domains with binding specificity for serum albumin | |
| CA2892747C (en) | Binding proteins comprising at least two repeat domains against her2. | |
| RU2778346C2 (ru) | Рекомбинантные связывающие белки и их применение | |
| HK40006908A (en) | Recombinant binding proteins and their use | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |