NZ718283A - Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof - Google Patents

Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof

Info

Publication number
NZ718283A
NZ718283A NZ718283A NZ71828314A NZ718283A NZ 718283 A NZ718283 A NZ 718283A NZ 718283 A NZ718283 A NZ 718283A NZ 71828314 A NZ71828314 A NZ 71828314A NZ 718283 A NZ718283 A NZ 718283A
Authority
NZ
New Zealand
Prior art keywords
seq
amino acid
sequence
antibody
acid sequence
Prior art date
Application number
NZ718283A
Other languages
English (en)
Inventor
Olga Vasiljeva
Stephen Moore
Margaret Nguyen
Daniel Hostetter
Jeanne Flandez
Original Assignee
Cytomx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytomx Therapeutics Inc filed Critical Cytomx Therapeutics Inc
Priority to NZ756892A priority Critical patent/NZ756892A/en
Publication of NZ718283A publication Critical patent/NZ718283A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/95Fusion polypeptide containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ718283A 2013-09-25 2014-09-25 Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof NZ718283A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ756892A NZ756892A (en) 2013-09-25 2014-09-25 Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361882377P 2013-09-25 2013-09-25
US201461971332P 2014-03-27 2014-03-27
PCT/US2014/057523 WO2015048329A2 (en) 2013-09-25 2014-09-25 Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof

Publications (1)

Publication Number Publication Date
NZ718283A true NZ718283A (en) 2022-05-27

Family

ID=51691175

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ718283A NZ718283A (en) 2013-09-25 2014-09-25 Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof
NZ756892A NZ756892A (en) 2013-09-25 2014-09-25 Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ756892A NZ756892A (en) 2013-09-25 2014-09-25 Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof

Country Status (12)

Country Link
US (4) US20150087810A1 (enExample)
EP (1) EP3049111A2 (enExample)
JP (5) JP6915987B2 (enExample)
KR (3) KR102488220B1 (enExample)
CN (3) CN118165076A (enExample)
AU (3) AU2014324884B2 (enExample)
CA (2) CA3214529A1 (enExample)
IL (3) IL291329B1 (enExample)
MX (2) MX379106B (enExample)
NZ (2) NZ718283A (enExample)
RU (1) RU2715232C2 (enExample)
WO (1) WO2015048329A2 (enExample)

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