NZ603828A - Non-aqueous taxane pro-emulsion formulations and methods of making and using the same - Google Patents
Non-aqueous taxane pro-emulsion formulations and methods of making and using the sameInfo
- Publication number
- NZ603828A NZ603828A NZ603828A NZ60382811A NZ603828A NZ 603828 A NZ603828 A NZ 603828A NZ 603828 A NZ603828 A NZ 603828A NZ 60382811 A NZ60382811 A NZ 60382811A NZ 603828 A NZ603828 A NZ 603828A
- Authority
- NZ
- New Zealand
- Prior art keywords
- pro
- emulsion formulations
- component
- aqueous
- emulsion
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 title abstract 8
- 239000000839 emulsion Substances 0.000 title abstract 7
- 229940123237 Taxane Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 4
- 229960003668 docetaxel Drugs 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 239000003125 aqueous solvent Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33070510P | 2010-05-03 | 2010-05-03 | |
| PCT/US2011/034586 WO2011139899A2 (en) | 2010-05-03 | 2011-04-29 | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ603828A true NZ603828A (en) | 2015-09-25 |
Family
ID=44858719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ603828A NZ603828A (en) | 2010-05-03 | 2011-04-29 | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10842770B2 (enExample) |
| EP (1) | EP2566474B1 (enExample) |
| JP (1) | JP5824511B2 (enExample) |
| KR (1) | KR101752944B1 (enExample) |
| CN (2) | CN102970990A (enExample) |
| AP (1) | AP3552A (enExample) |
| AU (1) | AU2011248449B2 (enExample) |
| BR (1) | BR112012028037A2 (enExample) |
| CA (1) | CA2798180A1 (enExample) |
| CO (1) | CO6640232A2 (enExample) |
| EA (1) | EA027666B1 (enExample) |
| ES (1) | ES2652509T3 (enExample) |
| IL (1) | IL222785A0 (enExample) |
| MX (1) | MX341082B (enExample) |
| MY (1) | MY167224A (enExample) |
| NZ (1) | NZ603828A (enExample) |
| PH (1) | PH12012502163A1 (enExample) |
| SG (2) | SG10201503234SA (enExample) |
| TW (2) | TW201526889A (enExample) |
| UA (1) | UA109275C2 (enExample) |
| WO (1) | WO2011139899A2 (enExample) |
| ZA (1) | ZA201208229B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5824511B2 (ja) | 2010-05-03 | 2015-11-25 | テイコク ファーマ ユーエスエー インコーポレーテッド | 非水タキサンプロエマルジョン配合物ならびにそれを調製および使用する方法 |
| JP5847942B2 (ja) * | 2012-07-19 | 2016-01-27 | 富士フイルム株式会社 | タキサン系活性成分含有液体組成物、その製造方法及び液体製剤 |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| CN104720070A (zh) * | 2013-12-20 | 2015-06-24 | 财团法人食品工业发展研究所 | 微乳液预浓缩物和微乳液及其制备方法 |
| TWI531318B (zh) | 2013-12-20 | 2016-05-01 | 財團法人食品工業發展研究所 | 微乳液預濃縮物和微乳液暨其製備方法 |
| CN106176599A (zh) * | 2015-05-06 | 2016-12-07 | 江苏天士力帝益药业有限公司 | 一种卡巴他赛脂肪乳注射剂及其制备方法 |
| JP6292267B2 (ja) * | 2016-09-13 | 2018-03-14 | ニプロ株式会社 | ドセタキセル製剤 |
| CN110709105A (zh) * | 2017-03-31 | 2020-01-17 | 技术防卫株式会社 | 载有药物的非水系组合物及其制备方法 |
| JP2018115178A (ja) * | 2018-03-15 | 2018-07-26 | ニプロ株式会社 | ドセタキセル製剤 |
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