KR101752944B1 - 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법 - Google Patents

비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법 Download PDF

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Publication number
KR101752944B1
KR101752944B1 KR1020127030345A KR20127030345A KR101752944B1 KR 101752944 B1 KR101752944 B1 KR 101752944B1 KR 1020127030345 A KR1020127030345 A KR 1020127030345A KR 20127030345 A KR20127030345 A KR 20127030345A KR 101752944 B1 KR101752944 B1 KR 101752944B1
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KR
South Korea
Prior art keywords
emulsion
pro
docetaxel
oil
component
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Expired - Fee Related
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KR1020127030345A
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English (en)
Korean (ko)
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KR20130092992A (ko
Inventor
키이치로 나베타
Original Assignee
테이코쿠 팔마 유에스에이, 인코포레이티드
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020127030345A 2010-05-03 2011-04-29 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법 Expired - Fee Related KR101752944B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33070510P 2010-05-03 2010-05-03
US61/330,705 2010-05-03
PCT/US2011/034586 WO2011139899A2 (en) 2010-05-03 2011-04-29 Non-aqueous taxane pro-emulsion formulations and methods of making and using the same

Publications (2)

Publication Number Publication Date
KR20130092992A KR20130092992A (ko) 2013-08-21
KR101752944B1 true KR101752944B1 (ko) 2017-07-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127030345A Expired - Fee Related KR101752944B1 (ko) 2010-05-03 2011-04-29 비수성의 탁산 프로에멀젼 제제, 및 그의 제조 및 사용 방법

Country Status (22)

Country Link
US (2) US10842770B2 (enExample)
EP (1) EP2566474B1 (enExample)
JP (1) JP5824511B2 (enExample)
KR (1) KR101752944B1 (enExample)
CN (2) CN109745287A (enExample)
AP (1) AP3552A (enExample)
AU (1) AU2011248449B2 (enExample)
BR (1) BR112012028037A2 (enExample)
CA (1) CA2798180A1 (enExample)
CO (1) CO6640232A2 (enExample)
EA (1) EA027666B1 (enExample)
ES (1) ES2652509T3 (enExample)
IL (1) IL222785A0 (enExample)
MX (1) MX341082B (enExample)
MY (1) MY167224A (enExample)
NZ (1) NZ603828A (enExample)
PH (1) PH12012502163A1 (enExample)
SG (2) SG10201503234SA (enExample)
TW (2) TWI511726B (enExample)
UA (1) UA109275C2 (enExample)
WO (1) WO2011139899A2 (enExample)
ZA (1) ZA201208229B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX341082B (es) 2010-05-03 2016-08-08 Teikoku Pharma Usa Inc Formulaciones de pro-emulsion de taxano no acuosas y metodos para hacer y usar las mismas.
ES2687705T3 (es) * 2012-07-19 2018-10-26 Fujifilm Corporation Composición líquida que contiene un principio activo a base de taxano, proceso de producción de la misma y preparación medicinal líquida
JO3685B1 (ar) * 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
TWI531318B (zh) 2013-12-20 2016-05-01 財團法人食品工業發展研究所 微乳液預濃縮物和微乳液暨其製備方法
CN104720070A (zh) * 2013-12-20 2015-06-24 财团法人食品工业发展研究所 微乳液预浓缩物和微乳液及其制备方法
CN106176599A (zh) * 2015-05-06 2016-12-07 江苏天士力帝益药业有限公司 一种卡巴他赛脂肪乳注射剂及其制备方法
JP6292267B2 (ja) * 2016-09-13 2018-03-14 ニプロ株式会社 ドセタキセル製剤
CN110709105A (zh) * 2017-03-31 2020-01-17 技术防卫株式会社 载有药物的非水系组合物及其制备方法
JP2018115178A (ja) * 2018-03-15 2018-07-26 ニプロ株式会社 ドセタキセル製剤

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