NZ602693A - Immunogenic proteins and compositions for the treatment and prevention of streptococcus agalactiae - Google Patents

Immunogenic proteins and compositions for the treatment and prevention of streptococcus agalactiae

Info

Publication number
NZ602693A
NZ602693A NZ602693A NZ60269311A NZ602693A NZ 602693 A NZ602693 A NZ 602693A NZ 602693 A NZ602693 A NZ 602693A NZ 60269311 A NZ60269311 A NZ 60269311A NZ 602693 A NZ602693 A NZ 602693A
Authority
NZ
New Zealand
Prior art keywords
seq
fragment
amino acid
acid sequence
polypeptide
Prior art date
Application number
NZ602693A
Other languages
English (en)
Inventor
Guido Grandi
Domenico Maione
Cira Daniela Rinaudo
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NZ602693A publication Critical patent/NZ602693A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ602693A 2010-04-01 2011-04-01 Immunogenic proteins and compositions for the treatment and prevention of streptococcus agalactiae NZ602693A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1005625.7A GB201005625D0 (en) 2010-04-01 2010-04-01 Immunogenic proteins and compositions
PCT/IB2011/051415 WO2011121576A2 (en) 2010-04-01 2011-04-01 Immunogenic proteins and compositions

Publications (1)

Publication Number Publication Date
NZ602693A true NZ602693A (en) 2014-07-25

Family

ID=42228832

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ602693A NZ602693A (en) 2010-04-01 2011-04-01 Immunogenic proteins and compositions for the treatment and prevention of streptococcus agalactiae

Country Status (12)

Country Link
US (4) US9079946B2 (https=)
EP (1) EP2552477B1 (https=)
JP (2) JP5960121B2 (https=)
CN (1) CN102917729B (https=)
AU (1) AU2011234031B2 (https=)
CA (1) CA2795093A1 (https=)
ES (1) ES2740000T3 (https=)
GB (1) GB201005625D0 (https=)
MX (2) MX349948B (https=)
NZ (1) NZ602693A (https=)
SG (2) SG184151A1 (https=)
WO (1) WO2011121576A2 (https=)

Families Citing this family (13)

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GB201005625D0 (en) * 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
AR101455A1 (es) * 2014-08-05 2016-12-21 Glaxosmithkline Biologicals Sa Molécula portadora
US11612664B2 (en) 2016-04-05 2023-03-28 Gsk Vaccines S.R.L. Immunogenic compositions
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
CA3066020A1 (en) 2017-06-16 2018-12-20 Glaxosmithkline Biologicals Sa Method of treatment
GB201711274D0 (en) 2017-07-13 2017-08-30 Glaxosmithkline Biologicals Sa Novel intermediates for the preperation of GBS polysaccharide antigens
CN108840914B (zh) * 2018-08-13 2022-07-01 内蒙古民族大学 一种具有免疫原性的多肽、其抗体的制备方法以及用途
US12533418B2 (en) 2019-11-22 2026-01-27 Glaxosmithkline Biologicals Sa Dosage and administration of a bacterial saccharide glycoconjugate vaccine
US20230303637A1 (en) 2020-06-12 2023-09-28 Glaxosmithkline Biologicals Sa Gbs ferritin nanoparticles
US20240024489A1 (en) 2020-11-20 2024-01-25 Institut Pasteur Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
CN115057944B (zh) * 2022-06-24 2025-06-24 南京农业大学 一种针对所有gbs血清型的多表位亚单位疫苗
GB202215634D0 (en) * 2022-10-21 2022-12-07 Glaxosmithkline Biologicals Sa Polypeptide scaffold
EP4682154A1 (en) 2024-07-17 2026-01-21 Institut Pasteur Protected tetrasaccharides, their process of preparation and their use in the synthesis of oligosaccharides representing segments of o-antigens from diverse shigella flexneri serotypes

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GB201005625D0 (en) * 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions

Also Published As

Publication number Publication date
AU2011234031A1 (en) 2012-10-25
US20170296645A1 (en) 2017-10-19
US20150343051A1 (en) 2015-12-03
JP2016098231A (ja) 2016-05-30
EP2552477A2 (en) 2013-02-06
EP2552477B1 (en) 2019-05-15
GB201005625D0 (en) 2010-05-19
WO2011121576A3 (en) 2011-12-29
US20130071416A1 (en) 2013-03-21
AU2011234031B2 (en) 2015-05-21
SG184151A1 (en) 2012-10-30
JP2013523718A (ja) 2013-06-17
MX349948B (es) 2017-08-22
CN102917729B (zh) 2016-01-20
US9079946B2 (en) 2015-07-14
JP5960121B2 (ja) 2016-08-02
SG10201502583VA (en) 2015-05-28
US9725488B2 (en) 2017-08-08
WO2011121576A2 (en) 2011-10-06
US9458229B2 (en) 2016-10-04
CN102917729A (zh) 2013-02-06
MX2012011157A (es) 2012-11-12
ES2740000T3 (es) 2020-02-05
US10086060B2 (en) 2018-10-02
CA2795093A1 (en) 2011-10-06
US20160362457A1 (en) 2016-12-15

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