NZ597512A - Novel fluorescent dyes and uses thereof - Google Patents

Novel fluorescent dyes and uses thereof

Info

Publication number
NZ597512A
NZ597512A NZ597512A NZ59751210A NZ597512A NZ 597512 A NZ597512 A NZ 597512A NZ 597512 A NZ597512 A NZ 597512A NZ 59751210 A NZ59751210 A NZ 59751210A NZ 597512 A NZ597512 A NZ 597512A
Authority
NZ
New Zealand
Prior art keywords
hydroxy
fluorescent dyes
disclosed
dimethyl
hydroxysuccinimide ester
Prior art date
Application number
NZ597512A
Other languages
English (en)
Inventor
Guoping Wang
Lakshmi S Kaanumalle
Hashem Akhavan-Tafti
Ravinder K Gupta
Silva Renuka De
Robert A Eickholt
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of NZ597512A publication Critical patent/NZ597512A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00Other synthetic dyes of known constitution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B7/00Indigoid dyes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/535Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NZ597512A 2009-07-16 2010-07-15 Novel fluorescent dyes and uses thereof NZ597512A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22598509P 2009-07-16 2009-07-16
PCT/US2010/042063 WO2011008912A1 (en) 2009-07-16 2010-07-15 Novel fluorescent dyes and uses thereof

Publications (1)

Publication Number Publication Date
NZ597512A true NZ597512A (en) 2014-03-28

Family

ID=43218117

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ597512A NZ597512A (en) 2009-07-16 2010-07-15 Novel fluorescent dyes and uses thereof

Country Status (12)

Country Link
US (2) US8367842B2 (enExample)
EP (1) EP2454329B1 (enExample)
JP (2) JP5777169B2 (enExample)
KR (1) KR101809758B1 (enExample)
CN (1) CN102498177B (enExample)
AU (1) AU2010273431B2 (enExample)
BR (1) BR112012001043A2 (enExample)
CA (1) CA2768352C (enExample)
IN (1) IN2012DN00454A (enExample)
NZ (1) NZ597512A (enExample)
SG (1) SG177676A1 (enExample)
WO (1) WO2011008912A1 (enExample)

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WO2011112966A1 (en) * 2010-03-11 2011-09-15 Promega Corporation Bioluminescent assays using cyanobenzothiazole compounds
CN102937576B (zh) * 2012-06-26 2015-10-21 广东德美精细化工股份有限公司 一种织物除油剂的防沾性能的评价方法
EP2719703A1 (en) * 2012-10-12 2014-04-16 Ecole Polytechnique Fédérale de Lausanne (EPFL) Precursor molecule for the synthesis of D-luciferin
CN102942537B (zh) * 2012-11-09 2014-07-02 浙江大学 一种用作pH荧光探针的苯并噻唑-苯胺类化合物及其制备方法
US9817929B1 (en) 2014-06-04 2017-11-14 Calypto Design Systems, Inc. Formal verification using microtransactions
KR20250012201A (ko) 2016-04-06 2025-01-23 소니그룹주식회사 스페이싱 링커 그룹을 포함하는 초고명도 이량체성 또는 중합체성 염료
EP3548470B1 (en) * 2016-12-01 2023-11-01 Promega Corporation 5,5-disubstituted luciferins and their use in luciferase-based assays
EP3802853A1 (en) * 2018-06-05 2021-04-14 Promega Corporation Luciferase enzymes for use with thermostable luciferins in bioluminescent assays
KR102854332B1 (ko) 2018-06-27 2025-09-03 소니그룹주식회사 디옥시리보오스를 포함하는 링커 군을 갖는 중합체성 염료
EP3820944A1 (en) * 2018-07-13 2021-05-19 Sony Corporation Polymeric dyes having a backbone comprising organophosphate units
CN110724114B (zh) * 2018-07-16 2022-10-21 北京工商大学 一种检测亚硫酸氢根及硫化氢的荧光探针
CN109633151B (zh) * 2018-12-26 2022-03-11 西北农林科技大学 一种肠炎沙门氏菌检测方法、试纸条及应用
CN110361378B (zh) * 2019-07-25 2021-04-02 浙江大学 基于荧光素乙酯的orac抗氧化活性评价方法及荧光指示剂
EP4034654A4 (en) * 2019-09-26 2024-03-27 Vidyasirimedhi Institute of Science and Technology LUCIFERIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION
WO2022125564A1 (en) 2020-12-07 2022-06-16 Sony Group Corporation Spacing linker group design for brightness enhancement in dimeric or polymeric dyes
KR20230158540A (ko) 2021-03-19 2023-11-20 칸토 덴카 코교 가부시키가이샤 D-루시페린 및 d-루시페린 유도체, 그리고 이들 화합물의 전구체, 그리고 이들의 제조 방법
CN116046735B (zh) * 2022-12-26 2025-08-22 南京大学 一种利用染料组成的传感器阵列检测全氟化合物的方法
CN119462681B (zh) * 2024-10-16 2025-09-30 聊城柏莱斯生物科技有限公司 一种荧光定量pcr参比染料及其制备方法与应用

Family Cites Families (16)

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DE3537877A1 (de) * 1985-10-24 1987-04-30 Geiger Reinhard Luciferin-derivate und immunoassays unter einsatz derartiger luciferin-derivate
DE68928412T2 (de) * 1988-07-08 1998-05-20 Jbl Scient Inc Herstellung und verwendung von fluoreszierenden benzothiazolderivaten
US6140051A (en) * 1997-07-21 2000-10-31 Promega Biosciences, Inc. Fluorescent dibenzazole derivatives and methods related thereto
AU7703400A (en) * 1999-09-14 2001-04-17 Xenoport, Inc. Substrates and screening methods for transport proteins
WO2003074566A2 (en) * 2002-03-01 2003-09-12 Immunomedics, Inc. Rs7 antibodies
US7541440B2 (en) * 2002-09-30 2009-06-02 Immunomedics, Inc. Chimeric, human and humanized anti-granulocyte antibodies and methods of use
CN100572555C (zh) * 2002-10-23 2009-12-23 犹他大学研究基金会 使用饱和染料的扩增子解链分析
DE10302787A1 (de) * 2003-01-24 2004-08-12 Schering Ag Hydrophile, Thiol-reaktive Cyaninfarbstoffe und deren Konjugate mit Biomolekülen für die Fluoreszenzdiagnostik
JP2006219381A (ja) * 2005-02-08 2006-08-24 Univ Of Electro-Communications 複素環化合物及び発光甲虫ルシフェラーゼ発光系用発光基質
EP3312292B1 (en) * 2005-05-31 2019-09-25 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
WO2007006019A1 (en) * 2005-07-06 2007-01-11 University Of South Florida Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression
KR100704007B1 (ko) * 2006-01-17 2007-04-04 한국과학기술연구원 화학발광 및 형광을 이용한 신속진단키트 및 이의 사용방법
JP5194258B2 (ja) * 2006-03-27 2013-05-08 国立大学法人電気通信大学 複素環化合物及び発光方法
WO2008147949A1 (en) * 2007-05-23 2008-12-04 Applera Corporation Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye
CN101270105B (zh) * 2008-04-08 2011-09-14 杨得锁 用于酶活性分析和酶抑制剂筛选的香豆素类化合物及合成方法
WO2010030343A1 (en) 2008-09-09 2010-03-18 Promega Corporation Bioluminescent assays using cyanobenzothiazole compounds

Also Published As

Publication number Publication date
KR20120037486A (ko) 2012-04-19
BR112012001043A2 (pt) 2016-03-15
IN2012DN00454A (enExample) 2015-05-15
JP2015165031A (ja) 2015-09-17
HK1168122A1 (en) 2012-12-21
JP2012533654A (ja) 2012-12-27
JP5777169B2 (ja) 2015-09-09
US20130131324A1 (en) 2013-05-23
SG177676A1 (en) 2012-02-28
CA2768352A1 (en) 2011-01-20
KR101809758B1 (ko) 2017-12-15
US8367842B2 (en) 2013-02-05
CN102498177A (zh) 2012-06-13
CA2768352C (en) 2016-10-11
WO2011008912A1 (en) 2011-01-20
EP2454329B1 (en) 2018-04-18
US8772501B2 (en) 2014-07-08
AU2010273431B2 (en) 2016-08-25
US20110014599A1 (en) 2011-01-20
AU2010273431A1 (en) 2012-02-02
CN102498177B (zh) 2014-12-24
AU2010273431A2 (en) 2012-03-01
EP2454329A1 (en) 2012-05-23

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