NZ594212A - Method for production of lactoferrin - Google Patents
Method for production of lactoferrinInfo
- Publication number
- NZ594212A NZ594212A NZ594212A NZ59421210A NZ594212A NZ 594212 A NZ594212 A NZ 594212A NZ 594212 A NZ594212 A NZ 594212A NZ 59421210 A NZ59421210 A NZ 59421210A NZ 594212 A NZ594212 A NZ 594212A
- Authority
- NZ
- New Zealand
- Prior art keywords
- lactoferrin
- milk
- angiogenin
- endotoxins
- lps
- Prior art date
Links
- 108010063045 Lactoferrin Proteins 0.000 title abstract 4
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title abstract 4
- 229940078795 lactoferrin Drugs 0.000 title abstract 4
- 235000021242 lactoferrin Nutrition 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000010445 Lactoferrin Human genes 0.000 title 1
- 239000002158 endotoxin Substances 0.000 abstract 4
- 102100032241 Lactotransferrin Human genes 0.000 abstract 3
- 102100022987 Angiogenin Human genes 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 108010072788 angiogenin Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 235000013336 milk Nutrition 0.000 abstract 2
- 239000008267 milk Substances 0.000 abstract 2
- 210000004080 milk Anatomy 0.000 abstract 2
- 239000002994 raw material Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 101710093543 Probable non-specific lipid-transfer protein Proteins 0.000 abstract 1
- 239000005862 Whey Substances 0.000 abstract 1
- 239000008351 acetate buffer Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 210000003022 colostrum Anatomy 0.000 abstract 1
- 235000021277 colostrum Nutrition 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 238000009928 pasteurization Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 235000020183 skimmed milk Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/30—Ion-exchange
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/34—Membrane process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20208809P | 2009-01-28 | 2009-01-28 | |
| PCT/IB2010/000149 WO2010112988A1 (en) | 2009-01-28 | 2010-01-28 | Method for production of lactoferrin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ594212A true NZ594212A (en) | 2013-01-25 |
Family
ID=41818728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ594212A NZ594212A (en) | 2009-01-28 | 2010-01-28 | Method for production of lactoferrin |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9115211B2 (https=) |
| EP (1) | EP2391225B1 (https=) |
| JP (1) | JP5718254B2 (https=) |
| CN (1) | CN102348387B (https=) |
| AU (1) | AU2010231075B2 (https=) |
| CA (1) | CA2750701C (https=) |
| DK (1) | DK2391225T3 (https=) |
| ES (1) | ES2805279T3 (https=) |
| NZ (1) | NZ594212A (https=) |
| PL (1) | PL2391225T3 (https=) |
| RU (1) | RU2579661C2 (https=) |
| WO (1) | WO2010112988A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013204850B2 (en) * | 2012-10-08 | 2015-06-25 | Murray Goulburn Co-Operative Co. Limited | Improved process for purifying milk proteins and products thereof |
| AU2013204858B2 (en) * | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
| RO130063A8 (ro) | 2014-08-28 | 2017-06-30 | Romvac Company S.A. | Producerea şi utilizarea ovotransferinei moderne () |
| WO2016136904A1 (ja) * | 2015-02-26 | 2016-09-01 | 味の素株式会社 | チーズの製造方法及びチーズ改質用の製剤 |
| FR3046603B1 (fr) | 2016-01-11 | 2017-12-29 | Michelin & Cie | Procede de modification d'un caoutchouc naturel et caoutchouc naturel modifie |
| US12447166B2 (en) | 2016-02-25 | 2025-10-21 | Applied Biological Laboratories, Inc. | Compositions and methods for protecting against airborne pathogens and irritants |
| US12594285B2 (en) | 2016-02-25 | 2026-04-07 | Applied Biological Laboratories, Inc. | Compositions and methods for protecting against airborne pathogens and irritants |
| MX2018010198A (es) | 2016-02-25 | 2019-06-12 | Applied Biological Laboratories Inc | Composiciones y metodos para proteger contra patogenos e irritantes transportados por el aire. |
| JP2022513594A (ja) | 2018-11-06 | 2022-02-09 | アルヘル プロジェクティランジェ イン インゼニリング ディー．オー．オー． | 乳、初乳及び酸性又は甘性ホエーから高度に精製されたラクトフェリン及びラクトペルオキシダーゼを製造する方法 |
| US20230001041A1 (en) | 2020-01-30 | 2023-01-05 | Nrl Pharma, Inc. | Sanitary product carrying lactoferrin |
| AU2020203454B1 (en) * | 2020-05-26 | 2021-07-22 | HPS Tech Pty Ltd | Processing protein |
| FR3115037B1 (fr) | 2020-10-12 | 2025-02-21 | Cie Laitiere Europeenne | Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue |
| MX2024002323A (es) * | 2021-08-23 | 2024-05-31 | Lactea Therapeutics Llc | Composiciones de lactoferrina y metodos de uso. |
| CA3229787A1 (en) * | 2021-08-23 | 2023-03-02 | Christopher HLUBB | Lactoferrin compositions and methods of use |
| US20250136666A1 (en) * | 2021-11-16 | 2025-05-01 | Noumi Limited | A method for producing a lactoferrin powder and uses thereof |
| DE202023102334U1 (de) | 2023-04-28 | 2023-06-07 | Mercurius Production Gmbh | Lactoferrin und Vorrichtung zu dessen Herstellung |
| PL248495B1 (pl) * | 2023-05-07 | 2025-12-22 | Polmlek Spolka Z Ograniczona Odpowiedzialnoscia | Sposób uzyskiwania laktoferyny w proszku z surowego mleka |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE61701B1 (en) | 1986-07-17 | 1994-11-30 | Morinaga Milk Industry Co Ltd | Process for producing bovine lactoferrin in high purity |
| US5571697A (en) * | 1989-05-05 | 1996-11-05 | Baylor College Of Medicine Texas Medical Center | Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus |
| JP2686831B2 (ja) * | 1989-09-22 | 1997-12-08 | 雪印乳業株式会社 | 鉄結合性蛋白質を分離、精製し、採取する方法 |
| US6096870A (en) * | 1994-01-05 | 2000-08-01 | Sepragen Corporation | Sequential separation of whey |
| ATE209862T1 (de) * | 1994-02-16 | 2001-12-15 | Pharming Intellectual Pty Bv | Isolierung von lactoferrin aus milch |
| JPH08217693A (ja) * | 1995-02-17 | 1996-08-27 | Yoshihisa Naito | 新規医薬組成物 |
| JP2974604B2 (ja) * | 1996-01-23 | 1999-11-10 | 雪印乳業株式会社 | 塩基性タンパク質組成物、塩基性ペプチド組成物及びその利用 |
| JPH1059864A (ja) * | 1996-08-15 | 1998-03-03 | Morinaga Milk Ind Co Ltd | 経口がん転移抑制剤 |
| JP2002326950A (ja) * | 2001-05-02 | 2002-11-15 | Meiji Milk Prod Co Ltd | 炎症性サイトカイン産生抑制剤 |
| US20030096736A1 (en) * | 2001-05-09 | 2003-05-22 | Kruzel Marian L. | Lactoferrin for age related disorders in humans |
| CN100467059C (zh) * | 2002-05-10 | 2009-03-11 | 阿根尼克斯有限公司 | 乳铁蛋白在治疗恶性肿瘤疾病中的用途 |
| US7238661B2 (en) * | 2002-05-24 | 2007-07-03 | Agennix, Inc. | Oral lactoferrin in the treatment of respiratory disorders |
| EP1712558A4 (en) * | 2004-02-03 | 2007-02-21 | Univ Kurume | PROCESS FOR SEPARATION / PURIFICATION OF CATIONIC PROTEIN |
| US20090306350A1 (en) * | 2005-05-13 | 2009-12-10 | Crea Biopharma Inc. | New purification method of lactoferrin |
| JP5087297B2 (ja) * | 2007-03-05 | 2012-12-05 | 森永乳業株式会社 | インターロイキン−１１産生促進剤 |
| CN101117351B (zh) * | 2007-04-30 | 2010-08-18 | 北京济普霖生物技术有限公司 | 一种从转基因牛乳中纯化重组人乳铁蛋白的方法 |
| US7919589B2 (en) * | 2007-07-10 | 2011-04-05 | Glanbia Nutritionals (Ireland), Ltd. | Method for removing endotoxin from proteins |
-
2010
- 2010-01-28 RU RU2011135536/10A patent/RU2579661C2/ru active
- 2010-01-28 WO PCT/IB2010/000149 patent/WO2010112988A1/en not_active Ceased
- 2010-01-28 ES ES10703352T patent/ES2805279T3/es active Active
- 2010-01-28 AU AU2010231075A patent/AU2010231075B2/en not_active Ceased
- 2010-01-28 PL PL10703352T patent/PL2391225T3/pl unknown
- 2010-01-28 NZ NZ594212A patent/NZ594212A/xx not_active IP Right Cessation
- 2010-01-28 DK DK10703352.4T patent/DK2391225T3/da active
- 2010-01-28 CA CA2750701A patent/CA2750701C/en not_active Expired - Fee Related
- 2010-01-28 JP JP2011546988A patent/JP5718254B2/ja not_active Expired - Fee Related
- 2010-01-28 EP EP10703352.4A patent/EP2391225B1/en active Active
- 2010-01-28 CN CN201080010953.6A patent/CN102348387B/zh not_active Expired - Fee Related
- 2010-01-28 US US13/146,798 patent/US9115211B2/en active Active - Reinstated
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010112988A1 (en) | 2010-10-07 |
| CN102348387A (zh) | 2012-02-08 |
| RU2011135536A (ru) | 2013-03-10 |
| ES2805279T3 (es) | 2021-02-11 |
| AU2010231075A1 (en) | 2011-08-18 |
| JP5718254B2 (ja) | 2015-05-13 |
| PL2391225T3 (pl) | 2020-11-16 |
| CN102348387B (zh) | 2014-12-31 |
| EP2391225A1 (en) | 2011-12-07 |
| US20110301077A1 (en) | 2011-12-08 |
| AU2010231075B2 (en) | 2015-06-11 |
| CA2750701A1 (en) | 2010-10-07 |
| US9115211B2 (en) | 2015-08-25 |
| EP2391225B1 (en) | 2020-05-06 |
| DK2391225T3 (da) | 2020-07-20 |
| JP2012516319A (ja) | 2012-07-19 |
| RU2579661C2 (ru) | 2016-04-10 |
| CA2750701C (en) | 2018-02-13 |
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