CN102348387B - 生产乳转铁蛋白的方法 - Google Patents

生产乳转铁蛋白的方法 Download PDF

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Publication number
CN102348387B
CN102348387B CN201080010953.6A CN201080010953A CN102348387B CN 102348387 B CN102348387 B CN 102348387B CN 201080010953 A CN201080010953 A CN 201080010953A CN 102348387 B CN102348387 B CN 102348387B
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lactotransferrin
lps
pharmaceutical composition
iron
solution
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CN102348387A (zh
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让-保罗·佩罗丹
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/30—Ion-exchange
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/34—Membrane process
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201080010953.6A 2009-01-28 2010-01-28 生产乳转铁蛋白的方法 Expired - Fee Related CN102348387B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20208809P 2009-01-28 2009-01-28
US61/202,088 2009-01-28
PCT/IB2010/000149 WO2010112988A1 (en) 2009-01-28 2010-01-28 Method for production of lactoferrin

Publications (2)

Publication Number Publication Date
CN102348387A CN102348387A (zh) 2012-02-08
CN102348387B true CN102348387B (zh) 2014-12-31

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CN201080010953.6A Expired - Fee Related CN102348387B (zh) 2009-01-28 2010-01-28 生产乳转铁蛋白的方法

Country Status (12)

Country Link
US (1) US9115211B2 (https=)
EP (1) EP2391225B1 (https=)
JP (1) JP5718254B2 (https=)
CN (1) CN102348387B (https=)
AU (1) AU2010231075B2 (https=)
CA (1) CA2750701C (https=)
DK (1) DK2391225T3 (https=)
ES (1) ES2805279T3 (https=)
NZ (1) NZ594212A (https=)
PL (1) PL2391225T3 (https=)
RU (1) RU2579661C2 (https=)
WO (1) WO2010112988A1 (https=)

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AU2013204850B2 (en) * 2012-10-08 2015-06-25 Murray Goulburn Co-Operative Co. Limited Improved process for purifying milk proteins and products thereof
AU2013204858B2 (en) * 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof
RO130063A8 (ro) 2014-08-28 2017-06-30 Romvac Company S.A. Producerea şi utilizarea ovotransferinei moderne ()
WO2016136904A1 (ja) * 2015-02-26 2016-09-01 味の素株式会社 チーズの製造方法及びチーズ改質用の製剤
FR3046603B1 (fr) 2016-01-11 2017-12-29 Michelin & Cie Procede de modification d'un caoutchouc naturel et caoutchouc naturel modifie
US12447166B2 (en) 2016-02-25 2025-10-21 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants
US12594285B2 (en) 2016-02-25 2026-04-07 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants
MX2018010198A (es) 2016-02-25 2019-06-12 Applied Biological Laboratories Inc Composiciones y metodos para proteger contra patogenos e irritantes transportados por el aire.
JP2022513594A (ja) 2018-11-06 2022-02-09 アルヘル プロジェクティランジェ イン インゼニリング ディー．オー．オー． 乳、初乳及び酸性又は甘性ホエーから高度に精製されたラクトフェリン及びラクトペルオキシダーゼを製造する方法
US20230001041A1 (en) 2020-01-30 2023-01-05 Nrl Pharma, Inc. Sanitary product carrying lactoferrin
AU2020203454B1 (en) * 2020-05-26 2021-07-22 HPS Tech Pty Ltd Processing protein
FR3115037B1 (fr) 2020-10-12 2025-02-21 Cie Laitiere Europeenne Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue
MX2024002323A (es) * 2021-08-23 2024-05-31 Lactea Therapeutics Llc Composiciones de lactoferrina y metodos de uso.
CA3229787A1 (en) * 2021-08-23 2023-03-02 Christopher HLUBB Lactoferrin compositions and methods of use
US20250136666A1 (en) * 2021-11-16 2025-05-01 Noumi Limited A method for producing a lactoferrin powder and uses thereof
DE202023102334U1 (de) 2023-04-28 2023-06-07 Mercurius Production Gmbh Lactoferrin und Vorrichtung zu dessen Herstellung
PL248495B1 (pl) * 2023-05-07 2025-12-22 Polmlek Spolka Z Ograniczona Odpowiedzialnoscia Sposób uzyskiwania laktoferyny w proszku z surowego mleka

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WO2006119644A1 (en) * 2005-05-13 2006-11-16 Crea Biopharma Inc. New purification method of lactoferrin
CN101117351A (zh) * 2007-04-30 2008-02-06 北京济普霖生物技术有限公司 一种从转基因牛乳中纯化重组人乳铁蛋白的方法
WO2009009706A1 (en) * 2007-07-10 2009-01-15 Glanbia Nutritionals Method for removing endotoxin from proteins

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Publication number Priority date Publication date Assignee Title
WO2006119644A1 (en) * 2005-05-13 2006-11-16 Crea Biopharma Inc. New purification method of lactoferrin
CN101117351A (zh) * 2007-04-30 2008-02-06 北京济普霖生物技术有限公司 一种从转基因牛乳中纯化重组人乳铁蛋白的方法
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Also Published As

Publication number Publication date
WO2010112988A1 (en) 2010-10-07
CN102348387A (zh) 2012-02-08
RU2011135536A (ru) 2013-03-10
ES2805279T3 (es) 2021-02-11
AU2010231075A1 (en) 2011-08-18
JP5718254B2 (ja) 2015-05-13
PL2391225T3 (pl) 2020-11-16
EP2391225A1 (en) 2011-12-07
US20110301077A1 (en) 2011-12-08
AU2010231075B2 (en) 2015-06-11
CA2750701A1 (en) 2010-10-07
US9115211B2 (en) 2015-08-25
EP2391225B1 (en) 2020-05-06
DK2391225T3 (da) 2020-07-20
NZ594212A (en) 2013-01-25
JP2012516319A (ja) 2012-07-19
RU2579661C2 (ru) 2016-04-10
CA2750701C (en) 2018-02-13

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