NZ590115A - Monoclonal antibodies having homosubtype cross -neutralization properties against influenza a viruses subtype h1 - Google Patents

Monoclonal antibodies having homosubtype cross -neutralization properties against influenza a viruses subtype h1

Info

Publication number
NZ590115A
NZ590115A NZ590115A NZ59011509A NZ590115A NZ 590115 A NZ590115 A NZ 590115A NZ 590115 A NZ590115 A NZ 590115A NZ 59011509 A NZ59011509 A NZ 59011509A NZ 590115 A NZ590115 A NZ 590115A
Authority
NZ
New Zealand
Prior art keywords
monoclonal antibodies
properties against
against influenza
viruses
neutralization properties
Prior art date
Application number
NZ590115A
Other languages
English (en)
Inventor
Roberto Burioni
Massimo Clementi
Original Assignee
Pomona Ricerca Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40303127&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ590115(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pomona Ricerca Srl filed Critical Pomona Ricerca Srl
Publication of NZ590115A publication Critical patent/NZ590115A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ590115A 2008-05-27 2009-05-27 Monoclonal antibodies having homosubtype cross -neutralization properties against influenza a viruses subtype h1 NZ590115A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000398A ITTO20080398A1 (it) 2008-05-27 2008-05-27 Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
PCT/IB2009/052212 WO2009144667A1 (en) 2008-05-27 2009-05-27 Monoclonal antibodies having homosubtype cross -neutralization properties against influenza a viruses subtype h1

Publications (1)

Publication Number Publication Date
NZ590115A true NZ590115A (en) 2012-08-31

Family

ID=40303127

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ590115A NZ590115A (en) 2008-05-27 2009-05-27 Monoclonal antibodies having homosubtype cross -neutralization properties against influenza a viruses subtype h1

Country Status (17)

Country Link
US (1) US9243054B2 (enExample)
EP (1) EP2294084B2 (enExample)
JP (1) JP5792060B2 (enExample)
KR (1) KR101665146B1 (enExample)
CN (1) CN102124028B (enExample)
AU (1) AU2009252758B2 (enExample)
BR (1) BRPI0912285A2 (enExample)
CA (1) CA2725627C (enExample)
EA (1) EA022855B1 (enExample)
ES (1) ES2555486T5 (enExample)
IL (1) IL209499A (enExample)
IT (1) ITTO20080398A1 (enExample)
MX (1) MX2010012974A (enExample)
NZ (1) NZ590115A (enExample)
SG (1) SG191610A1 (enExample)
WO (1) WO2009144667A1 (enExample)
ZA (1) ZA201009273B (enExample)

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ITTO20080398A1 (it) 2008-05-27 2009-11-28 Pomona Biotechnologies Llc Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
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EP2552485B1 (en) * 2010-03-26 2017-03-08 Pomona Ricerca S.r.l. Full-length immunoglobulins of the igg isotype capable of recognizing a heterosubtype neutralizing epitope on the hemagglutinin stem region and their use as anti-influenza medicament
ITTO20110067A1 (it) * 2011-01-26 2012-07-27 Pomona Ricerca Srl Immunoglobuline intere di isotipo igg atte a riconoscere un epitopo di neutralizzazione eterosubtipica sulla regione stelo (stem region) dell'emoagglutinina e loro uso come medicamento antinfluenzale
CN102241768B (zh) * 2010-05-14 2013-12-25 中国科学院上海生命科学研究院 一种抗甲型h1n1流感病毒血凝素蛋白的抗体
JP2013540701A (ja) * 2010-08-12 2013-11-07 セラクローン サイエンシーズ, インコーポレイテッド 抗赤血球凝集素抗体組成物およびその使用方法
CN101988050B (zh) * 2010-12-09 2012-06-27 湖南出入境检验检疫局检验检疫技术中心 抗h1n1猪流感病毒血凝素蛋白单克隆抗体,杂交瘤细胞株及抗原捕获elisa试剂盒
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WO2012145572A1 (en) 2011-04-20 2012-10-26 The Trustees Of The University Of Pennsylvania Regimens and compositions for aav-mediated passive immunization of airborne pathogens
WO2013119793A1 (en) * 2012-02-07 2013-08-15 University Of Kansas Chemiluminescent nanoparticles and uses thereof
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
LT3052192T (lt) * 2013-10-02 2020-12-10 Medimmune, Llc Neutralizuojantys antikūnai prieš gripą a ir jų naudojimas
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JP6974943B2 (ja) 2014-05-13 2021-12-01 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 2種の抗体構築物を発現するaavを含む組成物およびこの使用
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US11535665B2 (en) 2015-05-13 2022-12-27 The Trustees Of The University Of Pennsylvania AAV-mediated expression of anti-influenza antibodies and methods of use thereof
PL3303384T3 (pl) 2015-06-01 2022-01-03 Medimmune, Llc Neutralizujące cząsteczki wiążące przeciw grypie i ich zastosowania
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CA3010313A1 (en) 2016-01-13 2017-07-20 Medimmune, Llc Method of treating influenza a
CA3015347A1 (en) 2016-02-24 2017-08-31 Visterra, Inc. Formulations of antibody molecules to influenza virus
WO2018160573A1 (en) 2017-02-28 2018-09-07 The Trustees Of The University Of Pennsylvania Influenza vaccines based on aav vectors
JOP20190200A1 (ar) 2017-02-28 2019-08-27 Univ Pennsylvania تركيبات نافعة في معالجة ضمور العضل النخاعي
WO2018160582A1 (en) 2017-02-28 2018-09-07 The Trustees Of The University Of Pennsylvania Adeno-associated virus (aav) clade f vector and uses therefor
KR101972238B1 (ko) * 2017-11-22 2019-04-24 한국생명공학연구원 인플루엔자 a 바이러스 특이적 항체 또는 그의 항원 결합 단편
EP3946613A1 (en) 2019-03-25 2022-02-09 Visterra, Inc. Compositions and methods for treating and preventing influenza
JP2023551903A (ja) 2020-12-01 2023-12-13 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 組織特異的標的化モチーフを有する新規組成物及びそれを含有する組成物
EP4329885A1 (en) 2021-04-27 2024-03-06 Generation Bio Co. Non-viral dna vectors expressing therapeutic antibodies and uses thereof
JP2025509607A (ja) 2022-03-14 2025-04-11 ジェネレーション バイオ カンパニー 異種プライムブーストワクチン組成物及び使用の方法
CN121175327A (zh) * 2023-05-23 2025-12-19 斯克里普斯研究学院 作为流感疫苗抗原的稳定的血凝素(ha)三聚体
CN121021682A (zh) * 2025-10-29 2025-11-28 山东第一医科大学(山东省医学科学院) 一种抗甲型h1n1亚型猪流感病毒的重组纳米抗体及其制备方法和应用

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Also Published As

Publication number Publication date
AU2009252758B2 (en) 2014-07-31
KR101665146B1 (ko) 2016-10-11
MX2010012974A (es) 2011-01-21
IL209499A (en) 2016-10-31
WO2009144667A1 (en) 2009-12-03
CN102124028A (zh) 2011-07-13
ES2555486T5 (es) 2019-02-15
EP2294084A1 (en) 2011-03-16
ES2555486T3 (es) 2016-01-04
EA022855B1 (ru) 2016-03-31
IL209499A0 (en) 2011-01-31
KR20110020865A (ko) 2011-03-03
ITTO20080398A1 (it) 2009-11-28
AU2009252758A1 (en) 2009-12-03
EP2294084B2 (en) 2018-09-05
US20110076265A1 (en) 2011-03-31
EP2294084B1 (en) 2015-09-09
BRPI0912285A2 (pt) 2015-10-20
JP2011524161A (ja) 2011-09-01
CA2725627C (en) 2019-08-06
ZA201009273B (en) 2012-05-01
JP5792060B2 (ja) 2015-10-07
CA2725627A1 (en) 2009-12-03
EA201071365A1 (ru) 2011-08-30
CN102124028B (zh) 2015-05-20
SG191610A1 (en) 2013-07-31
US9243054B2 (en) 2016-01-26

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