NZ545385A - Prion-specific peptide reagents - Google Patents

Prion-specific peptide reagents

Info

Publication number
NZ545385A
NZ545385A NZ545385A NZ54538504A NZ545385A NZ 545385 A NZ545385 A NZ 545385A NZ 545385 A NZ545385 A NZ 545385A NZ 54538504 A NZ54538504 A NZ 54538504A NZ 545385 A NZ545385 A NZ 545385A
Authority
NZ
New Zealand
Prior art keywords
prion
pathogenic
peptide reagent
conformational
peptide
Prior art date
Application number
NZ545385A
Other languages
English (en)
Inventor
Melissa D Michelitsch
Celine Hu
Ronald N Zuckermann
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Priority to NZ580256A priority Critical patent/NZ580256A/en
Publication of NZ545385A publication Critical patent/NZ545385A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
NZ545385A 2003-08-13 2004-08-13 Prion-specific peptide reagents NZ545385A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ580256A NZ580256A (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents comprising the sequence KKRPKPGG

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49496203P 2003-08-13 2003-08-13
US57036804P 2004-05-12 2004-05-12
US58650904P 2004-07-09 2004-07-09
PCT/US2004/026363 WO2005016127A2 (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents

Publications (1)

Publication Number Publication Date
NZ545385A true NZ545385A (en) 2010-12-24

Family

ID=34198970

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ545385A NZ545385A (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents
NZ580256A NZ580256A (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents comprising the sequence KKRPKPGG

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ580256A NZ580256A (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents comprising the sequence KKRPKPGG

Country Status (13)

Country Link
US (1) US7439041B2 (enExample)
EP (1) EP1653844B1 (enExample)
JP (3) JP4709149B2 (enExample)
KR (1) KR101166012B1 (enExample)
AU (2) AU2004264953B2 (enExample)
BR (1) BRPI0413495A (enExample)
CA (1) CA2535261C (enExample)
DK (1) DK1653844T3 (enExample)
ES (1) ES2398394T3 (enExample)
IL (1) IL173480A0 (enExample)
MX (1) MXPA06001588A (enExample)
NZ (2) NZ545385A (enExample)
WO (1) WO2005016127A2 (enExample)

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US20050026165A1 (en) * 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
AU2002320045B2 (en) * 2001-05-31 2008-05-08 Adlyfe, Inc. Misfolded protein sensor method
ES2398394T3 (es) * 2003-08-13 2013-03-15 Novartis Vaccines And Diagnostics, Inc. Reactivos peptídicos específicos de prión
US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
US20060057671A1 (en) * 2004-09-10 2006-03-16 Orser Cindy S Immobilized probes and methods of detecting conformationally altered prion proteins
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
WO2006076497A2 (en) 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Osplation of pathogenic prions
US20090130774A1 (en) * 2005-01-13 2009-05-21 David Peretz Elisa assays using prion-specific peptide reagents
EP1853915B1 (en) * 2005-02-15 2011-10-12 Adlyfe, Inc. Method for detecting misfolded proteins and prions
CN101189265B (zh) * 2005-06-01 2012-07-04 米克罗麦特股份公司 抗il2抗体
WO2007030804A1 (en) * 2005-09-09 2007-03-15 Novartis Ag Prion-specific peptoid reagents
GB0519198D0 (en) * 2005-09-20 2005-10-26 Univ Cambridge Tech Tse detection
JP5097206B2 (ja) * 2006-07-28 2012-12-12 エイディーライフ インコーポレイティッド 診断および治療のためのペプチドプローブ
EP2140272A1 (en) * 2007-04-04 2010-01-06 Novartis Ag Prion elisa
JP2010523977A (ja) * 2007-04-04 2010-07-15 ノバルティス アーゲー プリオンアッセイ
WO2009041902A1 (en) * 2007-09-25 2009-04-02 Loefgren Kajsa Prion protein derived cell penetrating peptides and their uses
US8709472B1 (en) * 2007-11-13 2014-04-29 Abbott Cardiovascular Systems Inc. Bioactive agent-loaded heart-targeting nanoparticles
JP2011520108A (ja) * 2008-04-30 2011-07-14 ノバルティス アーゲー 病原性配座異性体についてのアッセイ
EP2128618A1 (en) * 2008-05-30 2009-12-02 Prion Diagnostica S.r.l. A process for monitoring the presence of pathogenic agents in biological fluids by nanostructured materials
US20100129290A1 (en) * 2008-11-26 2010-05-27 I.S.T. Corporation Smart contrast agent and detection method for detecting transition metal ions
US10266585B2 (en) 2009-08-28 2019-04-23 The Board Of Regents Of The Univerity Of Texas System Methods of treating brain injury
CA2817973C (en) 2010-10-15 2019-06-25 The Board Of Regents Of The University Of Texas System Antibodies that bind amyloid oligomers
WO2017066454A2 (en) 2015-10-14 2017-04-20 X-Therma, Inc. Compositions and methods for reducing ice crystal formation
KR102201144B1 (ko) * 2016-05-10 2021-01-11 엘지전자 주식회사 이동 로봇 및 그 제어방법
US11000571B2 (en) * 2016-06-27 2021-05-11 Florida State University Research Foundation, Inc. Modified fragments from the octarepeat region of prion protein as hemin binders
US11660325B2 (en) 2016-09-19 2023-05-30 University Of Houston System Compositions and methods of targeting cancer stem cells
JP2021004175A (ja) * 2017-09-04 2021-01-14 国立大学法人東北大学 コンフォメーション病治療用材料、及びその製造方法、並びにコンフォメーション病医薬のスクリーニング方法

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EP1416280A3 (en) 1995-09-14 2005-08-10 The Regents of the University of California Antibodies specific for native PrPsc
US5750361A (en) 1995-11-02 1998-05-12 The Regents Of The University Of California Formation and use of prion protein (PRP) complexes
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JP5122705B2 (ja) 1999-01-25 2013-01-16 ミナーヴァ・バイオテクノロジーズ・コーポレーション 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出
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BR0012765A (pt) 1999-07-27 2002-04-02 Imp College Innovations Ltd Peptìdeo, métodos de fabricar um anticorpo, de fabricar um agente de ligação capaz de ligar-se a uma forma celular de uma proteìna de prion, de remover uma forma celular de uma proteìna de prion de uma amostra, e de usar um anticorpo e/ou agente de ligação, anticorpo, agente de ligação, uso de um anticorpo ou agente de ligação, kit, e , sequência de peptìdeo de uma forma celular de uma proteìna de prion
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JP4783727B2 (ja) 2003-04-04 2011-09-28 パソゲン リムーバル アンド ダイアグノスティック テクノロジーズ インコーポレーテッド プリオンタンパク質結合物質と使用法
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ES2398394T3 (es) * 2003-08-13 2013-03-15 Novartis Vaccines And Diagnostics, Inc. Reactivos peptídicos específicos de prión
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US20060057671A1 (en) 2004-09-10 2006-03-16 Orser Cindy S Immobilized probes and methods of detecting conformationally altered prion proteins

Also Published As

Publication number Publication date
AU2009225337A1 (en) 2009-11-05
HK1090275A1 (en) 2006-12-22
IL173480A0 (en) 2006-06-11
AU2004264953A1 (en) 2005-02-24
EP1653844A4 (en) 2009-01-14
KR101166012B1 (ko) 2012-07-23
NZ580256A (en) 2011-07-29
KR20060066088A (ko) 2006-06-15
JP2013033060A (ja) 2013-02-14
ES2398394T3 (es) 2013-03-15
JP2010158247A (ja) 2010-07-22
CA2535261A1 (en) 2005-02-24
AU2009225337B2 (en) 2012-12-06
WO2005016127A3 (en) 2006-12-21
US20050118645A1 (en) 2005-06-02
DK1653844T3 (da) 2013-03-11
EP1653844B1 (en) 2012-12-12
US7439041B2 (en) 2008-10-21
BRPI0413495A (pt) 2006-10-17
WO2005016127A2 (en) 2005-02-24
EP1653844A2 (en) 2006-05-10
JP2007502120A (ja) 2007-02-08
CA2535261C (en) 2015-11-24
JP4709149B2 (ja) 2011-06-22
MXPA06001588A (es) 2006-08-25
AU2004264953B2 (en) 2009-07-23

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Free format text: THE TITLE HAS BEEN CORRECTED TO TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 04 SEP 2007; STATUS: REJECTED; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 29 NOV 2010; STATUS: OVERWRITTEN; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 14 JUL 2008; STATUS: REJECTED; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 14 OCT 2009; STATUS: REJECTED; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 11 NOV 2009; STATUS: REJECTED; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 26 MAY 2010; STATUS: REJECTED; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILING DATE: 24 DEC 2010; STATUS: SUPERSEDED; PUBLICATION DATE: 24 DEC 2010; TITLE: PRION-SPECIFIC PEPTIDE REAGENTS; FILI

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