BRPI0413495A - reagentes de peptìdeos especìficos para prìons e seus usos - Google Patents
reagentes de peptìdeos especìficos para prìons e seus usosInfo
- Publication number
- BRPI0413495A BRPI0413495A BRPI0413495-8A BRPI0413495A BRPI0413495A BR PI0413495 A BRPI0413495 A BR PI0413495A BR PI0413495 A BRPI0413495 A BR PI0413495A BR PI0413495 A BRPI0413495 A BR PI0413495A
- Authority
- BR
- Brazil
- Prior art keywords
- prion
- reagents
- peptide reagents
- specific peptide
- diseases
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2828—Prion diseases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
Abstract
"REAGENTES DE PEPTìDEOS ESPECìFICOS PARA PRìONS E SEUS USOS". São descritos reagentes de peptídeos que interagem preferencialmente com a forma PrP¬ sc¬ da proteína de príon. Também são descritos métodos de uso dos reagentes ou anticorpos para os reagentes para detecção, diagnóstico, purificação, terapia e profilaxia para doenças por príons e doenças associadas a príons.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49496203P | 2003-08-13 | 2003-08-13 | |
US57036804P | 2004-05-12 | 2004-05-12 | |
US58650904P | 2004-07-09 | 2004-07-09 | |
PCT/US2004/026363 WO2005016127A2 (en) | 2003-08-13 | 2004-08-13 | Prion-specific peptide reagents |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0413495A true BRPI0413495A (pt) | 2006-10-17 |
Family
ID=34198970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0413495-8A BRPI0413495A (pt) | 2003-08-13 | 2004-08-13 | reagentes de peptìdeos especìficos para prìons e seus usos |
Country Status (14)
Country | Link |
---|---|
US (1) | US7439041B2 (pt) |
EP (1) | EP1653844B1 (pt) |
JP (3) | JP4709149B2 (pt) |
KR (1) | KR101166012B1 (pt) |
AU (2) | AU2004264953B2 (pt) |
BR (1) | BRPI0413495A (pt) |
CA (1) | CA2535261C (pt) |
DK (1) | DK1653844T3 (pt) |
ES (1) | ES2398394T3 (pt) |
HK (1) | HK1090275A1 (pt) |
IL (1) | IL173480A0 (pt) |
MX (1) | MXPA06001588A (pt) |
NZ (2) | NZ580256A (pt) |
WO (1) | WO2005016127A2 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050026165A1 (en) * | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
CA2448981C (en) * | 2001-05-31 | 2014-03-18 | Arete Associates | Misfolded protein sensor method |
US20060035242A1 (en) * | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
WO2005016127A2 (en) * | 2003-08-13 | 2005-02-24 | Chiron Corporation | Prion-specific peptide reagents |
US20060057671A1 (en) * | 2004-09-10 | 2006-03-16 | Orser Cindy S | Immobilized probes and methods of detecting conformationally altered prion proteins |
WO2006076497A2 (en) | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Osplation of pathogenic prions |
EP1848831A4 (en) * | 2005-01-13 | 2008-11-05 | Novartis Vaccines & Diagnostic | ELISA TESTS USING PRION-SPECIFIC PEPTIDE REAGENT |
WO2006076683A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Isolation and detection of pathogenic prions |
BRPI0607350A2 (pt) * | 2005-02-15 | 2009-09-01 | Adlyfe Inc | método para detecção da presença ou quantidade de uma proteìna erroneamente duplicada em uma amostra e kit |
AU2006254333B2 (en) * | 2005-06-01 | 2011-02-17 | Amgen Research (Munich) Gmbh | Anti-IL2 antibodies |
JP5209477B2 (ja) * | 2005-09-09 | 2013-06-12 | ノバルティス アーゲー | プリオンに特異的なペプトイド試薬 |
GB0519198D0 (en) * | 2005-09-20 | 2005-10-26 | Univ Cambridge Tech | Tse detection |
US8673579B2 (en) * | 2006-07-28 | 2014-03-18 | Adlyfe, Inc. | Peptide probes for diagnostics and therapeutics |
CA2684796A1 (en) * | 2007-04-04 | 2008-10-16 | Novartis Ag | Prion assay |
US20100291598A1 (en) * | 2007-04-04 | 2010-11-18 | David Peretz | Prion elisa |
WO2009041902A1 (en) * | 2007-09-25 | 2009-04-02 | Loefgren Kajsa | Prion protein derived cell penetrating peptides and their uses |
US8709472B1 (en) * | 2007-11-13 | 2014-04-29 | Abbott Cardiovascular Systems Inc. | Bioactive agent-loaded heart-targeting nanoparticles |
CN102083450A (zh) * | 2008-04-30 | 2011-06-01 | 诺华有限公司 | 致病性构象异构体的分析 |
EP2128618A1 (en) * | 2008-05-30 | 2009-12-02 | Prion Diagnostica S.r.l. | A process for monitoring the presence of pathogenic agents in biological fluids by nanostructured materials |
US20100129290A1 (en) * | 2008-11-26 | 2010-05-27 | I.S.T. Corporation | Smart contrast agent and detection method for detecting transition metal ions |
US10266585B2 (en) | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
CA2817973C (en) | 2010-10-15 | 2019-06-25 | The Board Of Regents Of The University Of Texas System | Antibodies that bind amyloid oligomers |
AU2016338410B2 (en) | 2015-10-14 | 2021-07-15 | X-Therma, Inc. | Compositions and methods for reducing ice crystal formation |
US11231720B2 (en) * | 2016-05-10 | 2022-01-25 | Lg Electronics Inc. | Moving robot and control method thereof |
US11000571B2 (en) * | 2016-06-27 | 2021-05-11 | Florida State University Research Foundation, Inc. | Modified fragments from the octarepeat region of prion protein as hemin binders |
US11660325B2 (en) | 2016-09-19 | 2023-05-30 | University Of Houston System | Compositions and methods of targeting cancer stem cells |
JP2021004175A (ja) * | 2017-09-04 | 2021-01-14 | 国立大学法人東北大学 | コンフォメーション病治療用材料、及びその製造方法、並びにコンフォメーション病医薬のスクリーニング方法 |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2128362T3 (es) | 1991-12-03 | 1999-05-16 | Proteus Molecular Design | Fragmentos de proteinas de prion. |
AU4376093A (en) | 1992-05-15 | 1993-12-13 | Instituto Nazionale Neurologico C. Besta | Soluble prion polypeptides, and methods for detecting and purifying thereof |
US5948763A (en) | 1995-06-07 | 1999-09-07 | New York University | Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
BR9610580A (pt) | 1995-09-14 | 2000-10-24 | Univ California | Anticorpos especìficos para prpse nativos |
US5750361A (en) | 1995-11-02 | 1998-05-12 | The Regents Of The University Of California | Formation and use of prion protein (PRP) complexes |
DE69818388T2 (de) | 1997-02-06 | 2004-07-01 | Enfer Technology Ltd. | Immunoassay für spongiforme encephalopathien |
EP0861900A1 (en) | 1997-02-21 | 1998-09-02 | Erziehungsdirektion Of The Canton Zurich | Immunological detection of prions |
DE19741607A1 (de) | 1997-09-20 | 1999-03-25 | Prionics Ag | Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen |
EP1073723B1 (en) * | 1998-04-14 | 2005-08-17 | Sugen, Inc. | Ste20-related protein kinases |
US6211149B1 (en) | 1998-08-03 | 2001-04-03 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors of formation of protease resistant prion protein |
FI982480A0 (fi) | 1998-11-17 | 1998-11-17 | Wallac Oy | Immunomääritys nisäkkäiden tarttuvan spongiomuotoisen aivotaudin määrittämiseksi |
EP1169646A2 (en) | 1999-01-25 | 2002-01-09 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
AU783484B2 (en) | 1999-06-23 | 2005-11-03 | Thallion Pharmaceuticals Inc. | Prion protein peptides and uses thereof |
BR0012765A (pt) | 1999-07-27 | 2002-04-02 | Imp College Innovations Ltd | Peptìdeo, métodos de fabricar um anticorpo, de fabricar um agente de ligação capaz de ligar-se a uma forma celular de uma proteìna de prion, de remover uma forma celular de uma proteìna de prion de uma amostra, e de usar um anticorpo e/ou agente de ligação, anticorpo, agente de ligação, uso de um anticorpo ou agente de ligação, kit, e , sequência de peptìdeo de uma forma celular de uma proteìna de prion |
CA2385743A1 (en) * | 1999-09-28 | 2001-04-05 | Universitat Zurich | Factors having prion-binding activity in serum and plasma and agents to detect transmissible spongiform encephalopathitis |
FR2801106B1 (fr) | 1999-11-12 | 2007-10-05 | Commissariat Energie Atomique | Procede de diagnostic d'une esst provoquee par une souche d'atnc dans un echantillon biologique et son utilisation dans le diagnostic differentiel des differentes souches d'atnc |
CA2405568A1 (en) | 2000-04-05 | 2001-10-18 | North Carolina State University | Prion-binding peptidic ligands and methods of using same |
US6642171B2 (en) * | 2000-04-28 | 2003-11-04 | Synuthane International, Inc. | Double metal cyanide catalysts containing polyglycol ether complexing agents |
WO2001097785A2 (en) | 2000-06-20 | 2001-12-27 | Caprion Pharmaceuticals Inc. | Basic copolymers for the treatment of prion-related-disease |
AU6408901A (en) | 2000-07-07 | 2002-01-21 | Applied Research Systems | Early diagnosis of conformational diseases |
GB0103508D0 (en) * | 2001-02-13 | 2001-03-28 | Univ Dundee | Screening method and agents |
CA2448981C (en) | 2001-05-31 | 2014-03-18 | Arete Associates | Misfolded protein sensor method |
CA2466841A1 (en) | 2001-11-21 | 2003-06-05 | New York University | Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid .beta., prion protein, amylin, .alpha.-synuclein, or polyglutamine repeats for induction of an immune response thereto |
AU2002358647A1 (en) | 2001-12-10 | 2003-06-23 | Laboratoires Serono Sa | Prion inhibiting peptides and derivatives thereof |
MXPA04008275A (es) | 2002-02-28 | 2005-04-25 | Microsens Biophage Ltd | Enlace de formas patologicas de proteinas de prion. |
NZ536054A (en) | 2002-04-09 | 2009-10-30 | Scripps Research Inst | Motif-grafted hybrid polypeptides and uses thereof |
US20040208919A1 (en) | 2002-06-13 | 2004-10-21 | Nicolau Yves C. | Vaccination against prion diseases |
DE10230141B4 (de) | 2002-07-04 | 2004-07-15 | Priontype Gmbh | Verfahren und Kit zur Anreicherung und zum Nachweis von veränderten Prion-Proteinen (PrPSc) |
EP1382971A1 (en) * | 2002-07-17 | 2004-01-21 | Pepscan Systems B.V. | Detection of prion disease |
US20060057636A1 (en) | 2002-08-21 | 2006-03-16 | Peter Heegaard | Composite peptide compounds for diagnosis and treatment of diseases caused by prion proteins |
US20040072236A1 (en) | 2002-09-27 | 2004-04-15 | Neil Cashman | PrPSc -interacting molecules and uses thereof |
WO2004037854A1 (en) | 2002-10-23 | 2004-05-06 | Centre For Research And Technology Hellas/Institute Of Agrobiotechnology In.A | Prion protein-binding peptide sequences |
WO2004046728A1 (en) | 2002-11-18 | 2004-06-03 | Prionics Ag | Method for the detection of prpsc |
NZ560410A (en) | 2002-12-03 | 2008-12-24 | Univ North Carolina State | Prion protein ligands and methods of use |
EP1457500A1 (en) | 2003-03-14 | 2004-09-15 | University of Zurich | Soluble hybrid prion proteins and their use in the diagnosis, prevention and treatment of transmissible spongiform encephalophathies |
SG187269A1 (en) | 2003-04-04 | 2013-02-28 | Univ North Carolina State | Prion protein binding materials and methods of use |
WO2004091523A2 (en) | 2003-04-14 | 2004-10-28 | American National Red Cross | Method for identifying ligands specific for structural isoforms of proteins |
WO2005016127A2 (en) * | 2003-08-13 | 2005-02-24 | Chiron Corporation | Prion-specific peptide reagents |
DE102004043782A1 (de) | 2004-09-08 | 2006-03-09 | Heinrich-Heine-Universität Düsseldorf | Polypeptide und Verfahren zur spezifischen Bindung von Prionen |
US20060057671A1 (en) | 2004-09-10 | 2006-03-16 | Orser Cindy S | Immobilized probes and methods of detecting conformationally altered prion proteins |
-
2004
- 2004-08-13 WO PCT/US2004/026363 patent/WO2005016127A2/en active Application Filing
- 2004-08-13 CA CA2535261A patent/CA2535261C/en not_active Expired - Fee Related
- 2004-08-13 EP EP04781105A patent/EP1653844B1/en active Active
- 2004-08-13 MX MXPA06001588A patent/MXPA06001588A/es active IP Right Grant
- 2004-08-13 AU AU2004264953A patent/AU2004264953B2/en not_active Ceased
- 2004-08-13 NZ NZ580256A patent/NZ580256A/en not_active IP Right Cessation
- 2004-08-13 DK DK04781105.4T patent/DK1653844T3/da active
- 2004-08-13 JP JP2006523408A patent/JP4709149B2/ja not_active Expired - Fee Related
- 2004-08-13 KR KR1020067002997A patent/KR101166012B1/ko not_active IP Right Cessation
- 2004-08-13 BR BRPI0413495-8A patent/BRPI0413495A/pt not_active IP Right Cessation
- 2004-08-13 US US10/917,646 patent/US7439041B2/en not_active Expired - Fee Related
- 2004-08-13 NZ NZ545385A patent/NZ545385A/en not_active IP Right Cessation
- 2004-08-13 ES ES04781105T patent/ES2398394T3/es active Active
-
2006
- 2006-02-01 IL IL173480A patent/IL173480A0/en unknown
- 2006-11-08 HK HK06112300.4A patent/HK1090275A1/xx not_active IP Right Cessation
-
2009
- 2009-10-14 AU AU2009225337A patent/AU2009225337B2/en not_active Ceased
-
2010
- 2010-02-18 JP JP2010034088A patent/JP2010158247A/ja not_active Withdrawn
-
2012
- 2012-10-18 JP JP2012230552A patent/JP2013033060A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2535261C (en) | 2015-11-24 |
CA2535261A1 (en) | 2005-02-24 |
NZ545385A (en) | 2010-12-24 |
EP1653844B1 (en) | 2012-12-12 |
AU2004264953A1 (en) | 2005-02-24 |
MXPA06001588A (es) | 2006-08-25 |
HK1090275A1 (en) | 2006-12-22 |
EP1653844A2 (en) | 2006-05-10 |
KR101166012B1 (ko) | 2012-07-23 |
US7439041B2 (en) | 2008-10-21 |
EP1653844A4 (en) | 2009-01-14 |
JP2010158247A (ja) | 2010-07-22 |
DK1653844T3 (da) | 2013-03-11 |
JP2013033060A (ja) | 2013-02-14 |
JP4709149B2 (ja) | 2011-06-22 |
NZ580256A (en) | 2011-07-29 |
WO2005016127A2 (en) | 2005-02-24 |
AU2004264953B2 (en) | 2009-07-23 |
KR20060066088A (ko) | 2006-06-15 |
AU2009225337B2 (en) | 2012-12-06 |
AU2009225337A1 (en) | 2009-11-05 |
WO2005016127A3 (en) | 2006-12-21 |
JP2007502120A (ja) | 2007-02-08 |
ES2398394T3 (es) | 2013-03-15 |
IL173480A0 (en) | 2006-06-11 |
US20050118645A1 (en) | 2005-06-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) Free format text: ALTERADO DE: CHIRON CORPORATION |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. PAGAR RESTAURACAO. |
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B08J | Incorrect entry in the gazette republished [chapter 8.10 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2256 DE 01/04/2014. TEXTO CORRETO: REFERENTE AO NAO RECOLHIMENTO DA 4A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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