BR9610580A - Anticorpos especìficos para prpse nativos - Google Patents

Anticorpos especìficos para prpse nativos

Info

Publication number
BR9610580A
BR9610580A BR9610580-1A BR9610580A BR9610580A BR 9610580 A BR9610580 A BR 9610580A BR 9610580 A BR9610580 A BR 9610580A BR 9610580 A BR9610580 A BR 9610580A
Authority
BR
Brazil
Prior art keywords
prp
antibody
source
phage
bind
Prior art date
Application number
BR9610580-1A
Other languages
English (en)
Inventor
Stanley B Prusiner
R Anthony Williamson
Dennis R Burton
Original Assignee
Univ California
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24104278&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9610580(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ California, Scripps Research Inst filed Critical Univ California
Publication of BR9610580A publication Critical patent/BR9610580A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

ANTICORPOS ESPECìFICO PARA PrP^ se^ NATIVOS Priónios são patógenos infecciosos que causam encefalopatias esponjiformes do sistema nervoso central em humanos e animais. A presente invenção refere-se a métodos para obtenção de anticorpos que se ligam especialmente à isoforma do distúrbio degenerativo contagioso de ocorrência natural da proteína dos priónios (PrP^ se^) e a métodos para uso dos anticorpos para detectar PrP^ se^ em amostras.
BR9610580-1A 1995-09-14 1996-09-13 Anticorpos especìficos para prpse nativos BR9610580A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52810495A 1995-09-14 1995-09-14
PCT/US1996/014840 WO1997010505A1 (en) 1995-09-14 1996-09-13 ANTIBODIES SPECIFIC FOR NATIVE PrP?Sc¿

Publications (1)

Publication Number Publication Date
BR9610580A true BR9610580A (pt) 2000-10-24

Family

ID=24104278

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610580-1A BR9610580A (pt) 1995-09-14 1996-09-13 Anticorpos especìficos para prpse nativos

Country Status (12)

Country Link
US (6) US5846533A (pt)
EP (2) EP1416280A3 (pt)
JP (3) JP3495738B2 (pt)
AT (1) ATE263374T1 (pt)
AU (1) AU707484B2 (pt)
BR (1) BR9610580A (pt)
CA (1) CA2231409C (pt)
DE (2) DE852011T1 (pt)
ES (1) ES2218598T3 (pt)
MX (1) MX9802019A (pt)
NZ (1) NZ318689A (pt)
WO (1) WO1997010505A1 (pt)

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US20030228303A1 (en) 2003-12-11
WO1997010505A1 (en) 1997-03-20
EP0852011A4 (en) 2001-04-18
EP0852011A1 (en) 1998-07-08
CA2231409A1 (en) 1997-03-20
ATE263374T1 (de) 2004-04-15
US20050158803A1 (en) 2005-07-21
EP0852011B1 (en) 2004-03-31
MX9802019A (es) 1998-10-31
JP3586275B2 (ja) 2004-11-10
JP2004002439A (ja) 2004-01-08
US6372214B1 (en) 2002-04-16
DE69632056D1 (de) 2004-05-06
DE69632056T2 (de) 2004-12-30
EP1416280A2 (en) 2004-05-06
EP1416280A3 (en) 2005-08-10
DE852011T1 (de) 2001-10-11
CA2231409C (en) 2003-02-11
US6562341B2 (en) 2003-05-13
US20020150571A1 (en) 2002-10-17
AU7073596A (en) 1997-04-01
JP3495738B2 (ja) 2004-02-09
JP3586273B2 (ja) 2004-11-10
US5846533A (en) 1998-12-08
NZ318689A (en) 1999-02-25
JP2004002396A (ja) 2004-01-08
AU707484B2 (en) 1999-07-08
US7052675B2 (en) 2006-05-30
ES2218598T3 (es) 2004-11-16
US6290954B1 (en) 2001-09-18
US6858397B2 (en) 2005-02-22
JP2000500005A (ja) 2000-01-11

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