NZ337458A - A delta 5 desaturase for synthesis of PUFA's especially arachidonic acid (ARA) and compositions for synthesis of long chain polyunsaturated fatty acids - Google Patents

A delta 5 desaturase for synthesis of PUFA's especially arachidonic acid (ARA) and compositions for synthesis of long chain polyunsaturated fatty acids

Info

Publication number
NZ337458A
NZ337458A NZ337458A NZ33745898A NZ337458A NZ 337458 A NZ337458 A NZ 337458A NZ 337458 A NZ337458 A NZ 337458A NZ 33745898 A NZ33745898 A NZ 33745898A NZ 337458 A NZ337458 A NZ 337458A
Authority
NZ
New Zealand
Prior art keywords
synthesis
pufa
desaturase
ara
delta
Prior art date
Application number
NZ337458A
Other languages
English (en)
Inventor
Deborah Knutzon
Pradip Mukerji
Yung-Sheng Huang
Jennifer Thurmond
Sunita Chaudhary
Amanda Eun-Yeong Leonard
Original Assignee
Abbott Lab
Calgene Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab, Calgene Llc filed Critical Abbott Lab
Publication of NZ337458A publication Critical patent/NZ337458A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pediatric Medicine (AREA)
  • Animal Husbandry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
NZ337458A 1997-04-11 1998-04-10 A delta 5 desaturase for synthesis of PUFA's especially arachidonic acid (ARA) and compositions for synthesis of long chain polyunsaturated fatty acids NZ337458A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/833,610 US5972664A (en) 1997-04-11 1997-04-11 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
PCT/US1998/007422 WO1998046765A1 (en) 1997-04-11 1998-04-10 Methods and compositions for synthesis of long chain polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
NZ337458A true NZ337458A (en) 2000-07-28

Family

ID=25264859

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ337458A NZ337458A (en) 1997-04-11 1998-04-10 A delta 5 desaturase for synthesis of PUFA's especially arachidonic acid (ARA) and compositions for synthesis of long chain polyunsaturated fatty acids

Country Status (24)

Country Link
US (2) US5972664A (enEXAMPLES)
EP (1) EP1007691B1 (enEXAMPLES)
JP (1) JP4453881B2 (enEXAMPLES)
KR (2) KR20010006255A (enEXAMPLES)
CN (1) CN1253587A (enEXAMPLES)
AT (1) ATE277188T1 (enEXAMPLES)
AU (1) AU720725B2 (enEXAMPLES)
BG (1) BG103796A (enEXAMPLES)
BR (1) BR9809083A (enEXAMPLES)
CA (1) CA2286263A1 (enEXAMPLES)
DE (1) DE69826494T2 (enEXAMPLES)
DK (1) DK1007691T3 (enEXAMPLES)
ES (1) ES2229491T3 (enEXAMPLES)
HU (1) HUP0001295A3 (enEXAMPLES)
IL (1) IL132149A0 (enEXAMPLES)
IN (1) IN1998KO00639A (enEXAMPLES)
NO (1) NO994924L (enEXAMPLES)
NZ (1) NZ337458A (enEXAMPLES)
PL (1) PL336067A1 (enEXAMPLES)
PT (1) PT1007691E (enEXAMPLES)
SI (1) SI1007691T1 (enEXAMPLES)
SK (1) SK139799A3 (enEXAMPLES)
TR (1) TR199902466T2 (enEXAMPLES)
WO (1) WO1998046765A1 (enEXAMPLES)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6483008B1 (en) * 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
US6428990B1 (en) 1997-04-11 2002-08-06 Abbott Laboratories Human desaturase gene and uses thereof
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US7745694B1 (en) 1997-04-11 2010-06-29 Monsanto Technology Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US20030152983A1 (en) * 1997-12-23 2003-08-14 University Of Bristol Desaturase
EP1042485A2 (en) * 1997-12-23 2000-10-11 University Of Bristol Desaturase
WO1999061602A1 (en) * 1998-05-29 1999-12-02 Ohio University Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products
US6459018B1 (en) 1998-06-12 2002-10-01 Monsanto Technology Llc Polyunsaturated fatty acids in plants
US6677145B2 (en) * 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US20030163845A1 (en) 1998-09-02 2003-08-28 Pradip Mukerji Elongase genes and uses thereof
US6913916B1 (en) 1998-09-02 2005-07-05 Abbott Laboratories Elongase genes and uses thereof
WO2000020602A2 (en) * 1998-10-05 2000-04-13 Abbott Laboratories Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom
WO2000020603A1 (en) * 1998-10-05 2000-04-13 Abbott Laboratories Altered fatty acid biosynthesis in insect cells using delta five desaturase
US6140081A (en) * 1998-10-16 2000-10-31 The Scripps Research Institute Zinc finger binding domains for GNN
DE10030976A1 (de) 2000-06-30 2002-01-10 Basf Ag DELTA6-Desaturasegene exprimierende Pflanzen und PUFAS enthaltende Öle aus diesen Pflanzen und ein Verfahren zur Herstellung ungesättigter Fettsäuren
WO2001004636A1 (en) * 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
US7070970B2 (en) 1999-08-23 2006-07-04 Abbott Laboratories Elongase genes and uses thereof
BR0108198A (pt) 2000-02-09 2003-03-25 Basf Ag ácido nucleico isolado, construção de gene, sequência de aminoácidos, vetor, organismo, anticorpo, molécula de ácido nucleico anti-sentido, processo para a preparação de pufas, óleo, lipìdeo ou ácido graxo ou uma fração destes, composição, uso da composição oleaginosa, lipìdica ou de ácido graxo, kit, e, processo para identificar um antagonista de elongases
CN105483142A (zh) 2000-09-28 2016-04-13 生物源食物及科学公司 脂肪酸去饱和酶家族成员fad4、fad5、fad5-2和fad6及它们的应用
DE10102337A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
CA2435685C (en) * 2001-01-25 2011-06-07 Abbott Laboratories Desaturase genes and uses thereof
US6635451B2 (en) * 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
BR0306883A (pt) 2002-01-30 2004-12-07 Basf Plant Science Gmbh ácido nucléico isolado, sequências de ácido nucléico isolado e de aminoácido, construção de gene, vetor, organismo, processo para a produção de pufas, óleo, lipìdeo ou ácido graxo ou uma fração destes, composição de óleo, lipìdeo ou de ácido graxo, e, uso da mesma
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
BR122014000528B1 (pt) 2002-05-22 2016-02-16 Monsanto Technology Llc polinucleotídeo e vetor com atividade dessasturase no carbono 12 de molécula de ácido graxo, bem como método para produção de planta com óleo de semente contendo níveis alterados de ácidos graxos de ômega-3
WO2004057001A2 (en) 2002-12-19 2004-07-08 University Of Bristol Method for the production of polyunsaturated fatty acids
US20040172682A1 (en) * 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US8084074B2 (en) * 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
BRPI0407138A (pt) 2003-02-27 2006-01-10 Basf Plant Science Gmbh Sequência de ácido nucleico isolada, sequência de aminoácido, construção de gene, vetor, organismo transgênico não humano, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeo, ou um ácido graxo poliinsaturado ou uma fração dos mesmos, composições de óleo, de lipìdeos, ou de ácido graxo, e, uso do óleo, lipìdeos ou ácidos graxos ou de composições de óleo, de lipìdeos ou de ácido graxo
EP3121269A1 (de) 2003-03-31 2017-01-25 University Of Bristol Neue pflanzliche acyltransferase spezifisch für langkettige mehrfach ungesättigte fettsäuren
BRPI0409209A (pt) 2003-04-08 2006-03-28 Basf Plant Science Gmbh seqüência de ácido nucleico isolado, construto de gene, vetor, organismo não-humano transgênico, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeos ou ácidos graxos ou uma fração dos mesmos, composição de óleo, de lipìdeo ou de ácido graxo, e, uso de óleo, de lipìdeos ou de ácidos graxos ou de composição de óleo, de lipìdeo ou de ácido graxo
US7238482B2 (en) * 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7125672B2 (en) * 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
WO2005012316A2 (de) 2003-08-01 2005-02-10 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
WO2005021761A1 (en) * 2003-08-21 2005-03-10 Monsanto Technology Llc Fatty acid desaturases from primula
JP4916886B2 (ja) 2003-11-12 2012-04-18 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 油性植物および酵母中の多価不飽和脂肪酸レベルを変更するのに適したδ１５デサチュラーゼ
EP2333079B1 (en) 2004-01-20 2016-03-30 Monsanto Technology LLC Chimeric promoters for use in plants
CN1930277B (zh) 2004-02-27 2011-02-02 巴斯福植物科学有限公司 在转基因植物中产生多不饱和脂肪酸的方法
ATE528403T1 (de) 2004-02-27 2011-10-15 Basf Plant Science Gmbh Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
AU2005235081B2 (en) * 2004-04-16 2011-06-16 Monsanto Technology Llc Expression of fatty acid desaturases in corn
CA2563875C (en) 2004-04-22 2015-06-30 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CN102559364B (zh) 2004-04-22 2016-08-17 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
US20050266051A1 (en) * 2004-05-27 2005-12-01 The Procter & Gamble Company Pet food compositions and methods
ATE479757T1 (de) * 2004-06-04 2010-09-15 Fluxome Sciences As Stoffwechseltechnisch hergestellte zellen zur produktion mehrfach ungesättigter fettsäuren
AU2005267202B2 (en) * 2004-06-25 2011-10-27 Corteva Agriscience Llc Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
EP2194140A2 (en) 2005-03-02 2010-06-09 Metanomics GmbH Process for the production of fine chemicals
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
BRPI0611480B1 (pt) 2005-05-23 2016-06-07 Arcadia Biosciences Inc cártamo com ácido gama-linolênico elevado
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
EP1951866B1 (en) 2005-11-23 2014-07-30 E.I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US7723574B2 (en) 2005-11-24 2010-05-25 Basf Plant Science Gmbh Process for the production of Δ5-unsaturated fatty acids in transgenic organisms
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
EP1991047B1 (en) 2006-03-01 2012-09-26 Pioneer Hi-Bred International Inc. Compositions related to the quantitative trait locus 6 (qtl6) in maize and methods of use
US8629195B2 (en) 2006-04-08 2014-01-14 Bayer Materialscience Ag Production of polyurethane foams
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
EP2361986A1 (en) 2006-05-16 2011-08-31 Monsanto Technology LLC Use of non-agrobacterium bacterial species for plant transformation
US7695950B2 (en) * 2006-05-17 2010-04-13 E. I. Du Pont De Nemours And Company Δ5 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) * 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
ATE508186T1 (de) * 2006-07-19 2011-05-15 Monsanto Technology Llc Fettsäuredesaturasen aus tetraselmis suecica
US9029111B2 (en) 2006-08-24 2015-05-12 Basf Plant Science Gmbh Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
WO2008040787A2 (de) 2006-10-06 2008-04-10 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
PL2390338T3 (pl) * 2006-10-23 2014-01-31 Du Pont Delta-8 desaturazy i ich zastosowanie w wytwarzaniu polinienasyconych kwasów tłuszczowych
AU2008216707B2 (en) 2007-02-12 2014-06-19 E. I. Du Pont De Nemours And Company Production of arachidonic acid in oilseed plants
US7838729B2 (en) 2007-02-26 2010-11-23 Monsanto Technology Llc Chloroplast transit peptides for efficient targeting of DMO and uses thereof
US8030544B2 (en) 2007-03-09 2011-10-04 Monsanto Technology Llc Methods for plant transformation using spectinomycin selection
US7790156B2 (en) 2007-04-10 2010-09-07 E. I. Du Pont De Nemours And Company Δ-8 desaturases and their use in making polyunsaturated fatty acids
US8119860B2 (en) 2007-04-16 2012-02-21 E. I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US7943365B2 (en) 2007-05-03 2011-05-17 E.I. Du Pont De Nemours And Company Δ-5 desaturases and their use in making polyunsaturated fatty acids
WO2009016208A2 (de) 2007-07-31 2009-02-05 Basf Plant Science Gmbh Elongasen und verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
US20100263088A1 (en) 2007-12-14 2010-10-14 Basf Plant Science Gmbh Promoters From Brassica Napus For Seed Specific Gene Expression
MX2010011003A (es) 2008-04-07 2010-11-01 Monsanto Technology Llc Elementos regulatorios en las plantas y usos de los mismos.
EP2271223A2 (de) * 2008-04-25 2011-01-12 BASF Plant Science GmbH Pflanzensamenöl
CA2723072C (en) 2008-04-30 2017-01-10 Rothamsted Research Ltd. Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
US8168858B2 (en) * 2008-06-20 2012-05-01 E. I. Du Pont De Nemours And Company Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids
US8969066B2 (en) 2008-06-27 2015-03-03 Sapphire Energy, Inc. Induction of flocculation in photosynthetic organisms
EP3431607A3 (en) 2008-07-01 2019-03-06 BASF Plant Science GmbH Promoters from brassica napus for seed specific gene expression
CA2734810C (en) 2008-08-26 2018-06-19 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
US8268598B2 (en) * 2008-09-19 2012-09-18 E I Du Pont De Nemours And Company Mutant Δ5 desaturases mutated in the heme-binding motif (HPGG) and their use in making polyunsaturated fatty acids
CN113957105B (zh) 2008-11-18 2024-11-01 联邦科学技术研究组织 产生ω-3脂肪酸的酶和方法
CA2744930C (en) 2008-12-12 2018-03-20 Basf Plant Science Gmbh Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
US8060617B2 (en) * 2008-12-19 2011-11-15 Cisco Technology, Inc. Reserving network resources during scheduling of meeting event
US20120277117A1 (en) 2009-02-27 2012-11-01 Adel Zayed Hydroponic apparatus and methods of use
WO2010130725A1 (en) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
US8937214B2 (en) 2009-10-23 2015-01-20 Monsanto Technology Llc Methods and compositions for expression of transgenes in plants
EP3760726B1 (en) 2010-01-14 2024-10-30 Monsanto Technology LLC Plant regulatory elements and uses thereof
AU2011269059B2 (en) 2010-06-25 2016-01-28 Basf Plant Science Company Gmbh Acyltransferases and uses therof in fatty acid production
EP2609203B1 (en) 2010-08-26 2018-06-20 E. I. du Pont de Nemours and Company Recombinant microbial host cells for high eicosapentaenoic acid production
WO2012027698A1 (en) 2010-08-26 2012-03-01 E.I. Du Pont De Nemours And Company Mutant hpgg motif and hdash motif delta-5 desaturases and their use in making polyunsaturated fatty acids
NZ608144A (en) 2010-08-30 2014-12-24 Dow Agrosciences Llc Sugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics
WO2012083137A1 (en) 2010-12-17 2012-06-21 Monsanto Technology Llc Methods for improving competency of plant cells
MX356792B (es) 2011-03-25 2018-06-12 Monsanto Technology Llc Elementos de regulacion de plantas y sus usos.
MX395443B (es) 2011-05-13 2025-03-25 Monsanto Technology Llc Elementos reguladores de las plantas y sus usos.
IN2014DN06986A (enEXAMPLES) 2012-02-29 2015-04-10 Dow Agrosciences Llc
WO2013153404A1 (en) 2012-04-12 2013-10-17 Rothamsted Research Ltd Production of omega-3 long chain polyunsaturated fatty acids
US9663793B2 (en) 2012-04-20 2017-05-30 Monsanto Technology, Llc Plant regulatory elements and uses thereof
SG11201408362SA (en) 2012-06-15 2015-01-29 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
CN108893469B (zh) 2012-12-19 2022-09-02 孟山都技术公司 植物调控元件及其用途
ES2741223T3 (es) 2013-03-14 2020-02-10 Monsanto Technology Llc Elementos reguladores de plantas y usos de los mismos
MX2019011817A (es) 2013-03-14 2019-11-07 Monsanto Technology Llc Elementos reguladores de plantas y sus usos.
HUE055176T2 (hu) 2013-12-04 2021-11-29 Nippon Suisan Kaisha Ltd Mikrobiális olaj, eljárás mikrobiális olaj elõállítására, töményített mikrobiális olaj és eljárás töményített mikrobiális olaj elõállítására
CN111154724B (zh) 2013-12-18 2024-02-06 联邦科学技术研究组织 包含二十二碳六烯酸的提取的植物脂质
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
US20180228195A1 (en) * 2014-09-30 2018-08-16 Nestec S.A. Nutritional composition for use in promoting gut and/or liver maturation and/or repair
WO2016154631A1 (en) 2015-03-26 2016-09-29 The Texas A&M University System Conversion of lignin into bioplastics and lipid fuels
AU2016315655A1 (en) 2015-08-28 2018-02-01 E. I. Du Pont De Nemours And Company Ochrobactrum-mediated transformation of plants
MX390143B (es) 2015-10-02 2025-03-04 Monsanto Technology Llc Secuencias recombinantes de cromosoma b de maíz y sus usos
SG11201807333UA (en) 2016-03-11 2018-09-27 Monsanto Technology Llc Plant regulatory elements and uses thereof
CN109310062B (zh) 2016-05-24 2023-05-16 孟山都技术公司 植物调控元件和其用途
EP3475427A4 (en) 2016-06-28 2019-11-06 Monsanto Technology LLC METHOD AND COMPOSITIONS FOR USE IN GENOM MODIFICATION IN PLANTS
CA3029271A1 (en) 2016-06-28 2018-01-04 Cellectis Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
BR112019014797A2 (pt) 2017-01-19 2020-02-27 Monsanto Technology Llc Elementos reguladores de planta e usos dos mesmos
WO2019139616A1 (en) 2018-01-12 2019-07-18 The Texas A&M University System Increasing plant bioproduct yield
MX2021014528A (es) 2019-05-29 2022-01-06 Monsanto Technology Llc Metodos y composiciones para generar alelos dominantes usando edicion del genoma.
CN117120605A (zh) 2021-03-26 2023-11-24 旗舰创业创新七公司 用于产生环状多核糖核苷酸的组合物和方法
EP4314281A1 (en) 2021-03-26 2024-02-07 Flagship Pioneering Innovations VII, LLC Production of circular polyribonucleotides in a eukaryotic system
EP4314289A1 (en) 2021-03-26 2024-02-07 Flagship Pioneering Innovations VII, LLC Production of circular polyribonucleotides in a prokaryotic system
MX2024005239A (es) 2021-11-01 2024-07-22 Flagship Pioneering Innovations Vii Llc Polinucleotidos para modificar organismos.
US20250230452A1 (en) 2022-01-20 2025-07-17 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
AU2023337091A1 (en) 2022-09-09 2025-03-06 Eidgenössische Technische Hochschule Zürich Plant regulatory elements and uses thereof
WO2024091091A1 (ko) * 2022-10-28 2024-05-02 올케어플러스 주식회사 동물용 영양식 조성물 및 이의 제조 방법
AR132588A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de tymovirales artificiales
AR132585A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Sistemas de amplificación de arn satélite endornavirales para plantas
WO2024229385A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial ghabrivirales satellite rnas
AR132587A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de martellivirales artificiales
AR132591A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de secoviridae artificiales
AR132589A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de solemoviridae artificiales
WO2024229347A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial tombusviridae satellite rnas
WO2024229395A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Partitiviral satellite rna amplification systems for plants
AR132586A1 (es) 2023-05-03 2025-07-16 Flagship Pioneering Innovations Vii Llc Arn satélite de amalgavirus artificiales
US20250075226A1 (en) 2023-08-29 2025-03-06 University Of Freiburg Proteins for regulation of symbiotic infection and associated regulatory elements

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649295A (en) * 1970-06-01 1972-03-14 American Home Prod Humanized fat compositions and infant formulas thereof
US4058594A (en) * 1974-04-25 1977-11-15 John Williams Immuno-suppressive agents
EP0092076B1 (fr) * 1982-04-16 1986-12-17 Societe Des Produits Nestle S.A. Composition lipidique destinée à l'alimentation orale, entérale ou parentérale
US4670285A (en) * 1982-08-06 1987-06-02 The University Of Toronto Innovations Foundation Infant formula
GB8317248D0 (en) * 1983-06-24 1983-07-27 Wyeth John & Brother Ltd Fat compositions
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
US4920098A (en) * 1986-09-17 1990-04-24 Baxter International Inc. Nutritional support or therapy for individuals at risk or under treatment for atherosclerotic vascular, cardiovascular, and/or thrombotic diseases
US4843095A (en) * 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
US5057419A (en) * 1988-09-22 1991-10-15 Rutgers University Genetically engineered plasmid and organisms for the production of specialized oils
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5512482A (en) * 1990-04-26 1996-04-30 Calgene, Inc. Plant thioesterases
CA2083259C (en) * 1990-05-25 2007-05-15 William D. Hitz Nucleotide sequence of soybean stearoyl-acp desaturase gene
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
DE69231793T2 (de) * 1991-01-24 2001-11-08 Martek Corp., Columbia Mikrobielle öle und ihre verwendungen
JPH0591886A (ja) * 1991-09-30 1993-04-16 Suntory Ltd ８，１１−エイコサジエン酸及びこれを含有する脂質の製造方法
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5614393A (en) * 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
ATE242815T1 (de) * 1992-03-13 2003-06-15 Agrigenetics Inc Modifikation pflanzlicher öle durch verwendung von desaturase
WO1994011516A1 (en) 1992-11-17 1994-05-26 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
US7205457B1 (en) * 1993-02-05 2007-04-17 Monsanto Technology Llc Altered linolenic and linoleic acid content in plants
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US5654402A (en) * 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase

Also Published As

Publication number Publication date
HUP0001295A3 (en) 2003-10-28
ES2229491T3 (es) 2005-04-16
DK1007691T3 (da) 2004-12-20
PT1007691E (pt) 2005-02-28
JP2001523092A (ja) 2001-11-20
DE69826494D1 (de) 2004-10-28
NO994924L (no) 1999-11-30
BG103796A (bg) 2000-05-31
SI1007691T1 (en) 2005-02-28
EP1007691B1 (en) 2004-09-22
ATE277188T1 (de) 2004-10-15
SK139799A3 (en) 2000-05-16
IL132149A0 (en) 2001-03-19
CN1253587A (zh) 2000-05-17
DE69826494T2 (de) 2006-03-09
JP4453881B2 (ja) 2010-04-21
KR20010006258A (ko) 2001-01-26
CA2286263A1 (en) 1998-10-22
US6589767B1 (en) 2003-07-08
AU720725B2 (en) 2000-06-08
PL336067A1 (en) 2000-06-05
HUP0001295A1 (en) 2000-07-28
NO994924D0 (no) 1999-10-08
IN1998KO00639A (enEXAMPLES) 2005-03-18
US5972664A (en) 1999-10-26
EP1007691A1 (en) 2000-06-14
WO1998046765A1 (en) 1998-10-22
MX9909327A (es) 2000-04-30
KR20010006255A (ko) 2001-01-26
AU7114898A (en) 1998-11-11
TR199902466T2 (xx) 2000-07-21
BR9809083A (pt) 2000-08-01

Similar Documents

Publication Publication Date Title
NZ337458A (en) A delta 5 desaturase for synthesis of PUFA's especially arachidonic acid (ARA) and compositions for synthesis of long chain polyunsaturated fatty acids
NZ337459A (en) Nucleic acid construct in plants and dietary supplement
CY1106085T1 (el) Το ανθρωπινο γονιδιο της δελτα-5δεσατουρασης και οι χρησεις του
DE69405096D1 (de) Muttermilch-ersatzstoffe aus umgeestertentriglyceridmischungen
MY102058A (en) Enzyme inhibitors
PL322299A1 (en) Derivatives of insulin
HUT66057A (en) Interleukin 1beta protease and interleukin 1beta protease inhibitors
EP0751779A4 (en) SELECTIVE FUSEBLE COMPOUNDS BASED ON IMMINODEACETIC ACID ESTER BONDS
DE60227951D1 (de) Delta-4-desaturase-gene und ihre verwendung
MXPA03006663A (es) Genes de desaturasa y usos de los mismos.
AUPM767794A0 (en) Delivery of nucleic acids and peptides
CA2137378A1 (en) D-enzyme compositions and methods of their use
KR830004216A (ko) 아실펩타이드의 제조방법
AU1094892A (en) Improved activation of recombinant proteins
GR860399B (en) Process for obtaining peptidic derivatives pepstatine analogs renines inhibitors and proteases acids
EP1681350A3 (en) Porphorymonas gingivalis polypeptides and polynucleotides
KR970707162A (ko) II종 포스포리파제 A2 저해작용을 갖는 신규한 모노클로날 항체 및 그 일부를 포함하는 단백질(Novel monoclonal antibody having inhibitory effect on type II phospholipase A2 and protein containing a part of the same)
NO971621D0 (no) Keratinocyttvekstfaktoranaloger
WO1988000833A3 (en) Antipyretic and anti-inflammatory peptides
AR013618A1 (es) Metodo y composiciones para la distribucion y expresion de acidos nucleicos de interferon
DK0946590T3 (da) Dihydroxypropylcysteinpeptid og middel, der indeholder dette peptid
IL72489A0 (en) Preparation of polypeptides having an amide carboxyl terminal end
EP0933427A3 (en) Beta-carotene hydroxylase gene
EP0249412A3 (en) C-terminal alpha-amidating enzyme and process for production and use thereof
GB2188934A (en) Polypeptide production

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)