NZ331540A - Human bikunin - Google Patents

Human bikunin

Info

Publication number
NZ331540A
NZ331540A NZ331540A NZ33154097A NZ331540A NZ 331540 A NZ331540 A NZ 331540A NZ 331540 A NZ331540 A NZ 331540A NZ 33154097 A NZ33154097 A NZ 33154097A NZ 331540 A NZ331540 A NZ 331540A
Authority
NZ
New Zealand
Prior art keywords
placental
bikurun
seq
protein
sequence
Prior art date
Application number
NZ331540A
Other languages
English (en)
Inventor
Paul P Tamburini
Gary Davis
Katherine A Delaria
Christopher W Marlor
Daniel K Muller
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NZ331540A publication Critical patent/NZ331540A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • C07K14/8117Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Wood Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
NZ331540A 1996-03-11 1997-03-10 Human bikunin NZ331540A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1310696P 1996-03-11 1996-03-11
US1979396P 1996-06-14 1996-06-14
US72525196A 1996-10-04 1996-10-04
PCT/US1997/003894 WO1997033996A2 (en) 1996-03-11 1997-03-10 Human bikunin

Publications (1)

Publication Number Publication Date
NZ331540A true NZ331540A (en) 1999-10-28

Family

ID=27359773

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ331540A NZ331540A (en) 1996-03-11 1997-03-10 Human bikunin

Country Status (27)

Country Link
US (3) US6583108B1 (OSRAM)
EP (1) EP0891426B1 (OSRAM)
JP (2) JP3469584B2 (OSRAM)
KR (1) KR100356956B1 (OSRAM)
AR (3) AR006188A1 (OSRAM)
AT (1) ATE328083T1 (OSRAM)
AU (1) AU716923B2 (OSRAM)
BR (1) BR9708021A (OSRAM)
CA (1) CA2247888A1 (OSRAM)
CO (1) CO4600683A1 (OSRAM)
DE (1) DE69735996T2 (OSRAM)
DK (1) DK0891426T3 (OSRAM)
ES (1) ES2263174T3 (OSRAM)
HR (1) HRP970144B1 (OSRAM)
HU (1) HU226419B1 (OSRAM)
ID (1) ID16224A (OSRAM)
IL (1) IL126115A (OSRAM)
IN (1) IN192874B (OSRAM)
MY (1) MY120693A (OSRAM)
NZ (1) NZ331540A (OSRAM)
PA (1) PA8426301A1 (OSRAM)
PL (1) PL188387B1 (OSRAM)
PT (1) PT891426E (OSRAM)
SV (1) SV1997000018A (OSRAM)
TR (1) TR199801794T2 (OSRAM)
WO (1) WO1997033996A2 (OSRAM)
YU (1) YU8997A (OSRAM)

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US20040235715A1 (en) * 1999-11-12 2004-11-25 Bayer Corporation Method of producing glycosylated bikunin
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US7722536B2 (en) 2003-07-15 2010-05-25 Abbott Diabetes Care Inc. Glucose measuring device integrated into a holster for a personal area network device
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ATE551422T1 (de) 2005-02-18 2012-04-15 Angiochem Inc Aprotininpolypeptide zum transport einer verbindung durch die blut-hirn-schranke
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US9173891B2 (en) 2009-04-20 2015-11-03 Angiochem, Inc. Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
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Also Published As

Publication number Publication date
DK0891426T3 (da) 2006-10-02
IL126115A (en) 2007-03-08
AR058982A1 (es) 2008-03-05
HUP9902698A3 (en) 2001-06-28
CA2247888A1 (en) 1997-09-18
YU8997A (sh) 1999-09-27
HU226419B1 (en) 2008-12-29
PA8426301A1 (es) 2000-05-24
HRP970144B1 (en) 2004-10-31
EP0891426B1 (en) 2006-05-31
AR006188A1 (es) 1999-08-11
PT891426E (pt) 2006-10-31
KR100356956B1 (ko) 2003-03-15
US7452859B2 (en) 2008-11-18
US20030194398A1 (en) 2003-10-16
JP3469584B2 (ja) 2003-11-25
MY120693A (en) 2005-11-30
IL126115A0 (en) 1999-05-09
WO1997033996A2 (en) 1997-09-18
ID16224A (id) 1997-09-11
IN192874B (OSRAM) 2004-05-29
DE69735996T2 (de) 2007-02-15
KR19990087697A (ko) 1999-12-27
ES2263174T3 (es) 2006-12-01
EP0891426A2 (en) 1999-01-20
TR199801794T2 (xx) 2000-07-21
JP2004000208A (ja) 2004-01-08
DE69735996D1 (de) 2006-07-06
US7019123B2 (en) 2006-03-28
JP2001521367A (ja) 2001-11-06
AU2207797A (en) 1997-10-01
ATE328083T1 (de) 2006-06-15
HUP9902698A2 (hu) 1999-11-29
CO4600683A1 (es) 1998-05-08
BR9708021A (pt) 1999-07-27
SV1997000018A (es) 1999-01-14
PL188387B1 (pl) 2005-01-31
WO1997033996A3 (en) 1997-11-13
AR053063A2 (es) 2007-04-18
AU716923B2 (en) 2000-03-09
HRP970144A2 (en) 1998-04-30
US6583108B1 (en) 2003-06-24
US20060172946A1 (en) 2006-08-03
PL328822A1 (en) 1999-02-15

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