NZ274500A - 7-phenoxyalkyl-1,2,4-triazolo[1,5-a]pyrimidine derivatives; pharmaceutical compositions - Google Patents

7-phenoxyalkyl-1,2,4-triazolo[1,5-a]pyrimidine derivatives; pharmaceutical compositions

Info

Publication number
NZ274500A
NZ274500A NZ274500A NZ27450094A NZ274500A NZ 274500 A NZ274500 A NZ 274500A NZ 274500 A NZ274500 A NZ 274500A NZ 27450094 A NZ27450094 A NZ 27450094A NZ 274500 A NZ274500 A NZ 274500A
Authority
NZ
New Zealand
Prior art keywords
triazolo
pyrimidine
ethyl
formula
compounds
Prior art date
Application number
NZ274500A
Other languages
English (en)
Inventor
David John Heal
Fernandez Maria Isab Fernandez
Bruce Jeremy Sargent
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of NZ274500A publication Critical patent/NZ274500A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
NZ274500A 1993-10-13 1994-10-12 7-phenoxyalkyl-1,2,4-triazolo[1,5-a]pyrimidine derivatives; pharmaceutical compositions NZ274500A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939321162A GB9321162D0 (en) 1993-10-13 1993-10-13 Therapeutic agents

Publications (1)

Publication Number Publication Date
NZ274500A true NZ274500A (en) 1997-06-24

Family

ID=10743505

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ274500A NZ274500A (en) 1993-10-13 1994-10-12 7-phenoxyalkyl-1,2,4-triazolo[1,5-a]pyrimidine derivatives; pharmaceutical compositions

Country Status (31)

Country Link
US (1) US5753665A (enFirst)
EP (1) EP0723546B1 (enFirst)
JP (1) JPH09503771A (enFirst)
CN (1) CN1040537C (enFirst)
AT (1) ATE188966T1 (enFirst)
AU (1) AU679573B2 (enFirst)
BG (1) BG62405B1 (enFirst)
BR (1) BR9407812A (enFirst)
CA (1) CA2173857A1 (enFirst)
CZ (1) CZ106996A3 (enFirst)
DE (1) DE69422724T2 (enFirst)
DK (1) DK0723546T3 (enFirst)
ES (1) ES2142413T3 (enFirst)
FI (1) FI961630A7 (enFirst)
GB (1) GB9321162D0 (enFirst)
GR (1) GR3032480T3 (enFirst)
HU (1) HUT74580A (enFirst)
IL (1) IL111259A (enFirst)
IN (1) IN179169B (enFirst)
MY (1) MY112110A (enFirst)
NO (1) NO306509B1 (enFirst)
NZ (1) NZ274500A (enFirst)
PL (1) PL177920B1 (enFirst)
PT (1) PT723546E (enFirst)
RO (1) RO117020B1 (enFirst)
RU (1) RU2136684C1 (enFirst)
SK (1) SK282329B6 (enFirst)
TW (1) TW372237B (enFirst)
UA (1) UA42738C2 (enFirst)
WO (1) WO1995010521A1 (enFirst)
ZA (1) ZA947949B (enFirst)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506382D0 (en) * 1995-03-29 1995-05-17 Boots Co Plc Pharmaceutical compositions
GB9507348D0 (en) * 1995-04-08 1995-05-31 Knoll Ag Therapeutic agents
US5714607A (en) * 1995-12-01 1998-02-03 American Cyanamid Company Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
ATE236904T1 (de) 1996-07-25 2003-04-15 Merck Sharp & Dohme Substituierte triazolo-pyridazin-derivate als liganden von gaba-rezeptoren
GB9617727D0 (en) * 1996-08-23 1996-10-02 Knoll Ag Process
GB9626746D0 (en) * 1996-12-23 1997-02-12 Knoll Ag Process
DE19706336A1 (de) * 1997-02-19 1998-08-20 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Alkoholen
DE19706337A1 (de) 1997-02-19 1998-08-20 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Estern
DE19707008A1 (de) 1997-02-21 1998-08-27 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Alkoholen
JP2002527519A (ja) * 1998-10-16 2002-08-27 メルク シャープ エンド ドーム リミテッド Ｇａｂａ受容体のリガンドとしてのピラゾロトリアジン誘導体
GB9906126D0 (en) * 1999-03-18 1999-05-12 Knoll Ag Pharmaceutical formulations
GB9906130D0 (en) * 1999-03-18 1999-05-12 Knoll Ag Compounds for use in therapy
GB9906124D0 (en) * 1999-03-18 1999-05-12 Knoll Ag Therapeutic agent
GB9914743D0 (en) * 1999-06-24 1999-08-25 Knoll Ag Therapeutic agents
CA2413802A1 (en) * 2000-06-30 2002-01-10 Mark R. Schmitt Substituted-triazolopyrimidines as anticancer agents
TWI334868B (en) * 2003-06-03 2010-12-21 Nippon Kayaku Kk [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof
AU2005214167B2 (en) 2004-02-13 2008-08-07 Warner-Lambert Company Llc Androgen receptor modulators
CA2563291A1 (en) 2004-04-13 2005-10-27 Warner-Lambert Company Llc 4-cyano-phenoxy-alkyl carboxyl derivatives as androgen modulators
BRPI0509980A (pt) 2004-04-22 2007-10-16 Warner Lambert Co moduladores de androgênio
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
EP2328414B1 (en) * 2008-08-29 2013-12-11 Concert Pharmaceuticals Inc. Substituted triazolo-pyridazine derivatives
WO2010112484A1 (en) * 2009-04-01 2010-10-07 Neurosearch A/S SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
DK2414365T3 (da) 2009-04-01 2014-03-31 Aniona Aps SUBSTITUEREDE [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINER OG ANVENDELSE HERAF SOM KALIUMKANALMODULATORER
EP2438069A1 (en) 2009-04-01 2012-04-11 NeuroSearch A/S Substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as potassium channel modulators
CN113874377A (zh) 2019-05-13 2021-12-31 埃科莱布美国股份有限公司 作为铜腐蚀抑制剂的1,2,4-三唑并[1,5-a]嘧啶衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE46306B1 (en) * 1977-02-11 1983-05-04 Ici Ltd Safeguarded toxic chemical compositions containing an emetic
FR2549834B1 (fr) * 1983-07-25 1985-10-18 Sanofi Sa Derives de triazolo-pyrimidine, leur procede de preparation et leur application therapeutique en tant que tonicardiaques
WO1989001478A1 (en) * 1987-08-07 1989-02-23 The Australian National University ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES
US5387747A (en) * 1992-02-24 1995-02-07 Laboratoires Upsa Triazolopyrimidine derivatives which are angiotensin II receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present

Also Published As

Publication number Publication date
NO961435D0 (no) 1996-04-11
UA42738C2 (uk) 2001-11-15
HU9600959D0 (en) 1996-06-28
WO1995010521A1 (en) 1995-04-20
PT723546E (pt) 2000-04-28
TW372237B (en) 1999-10-21
ATE188966T1 (de) 2000-02-15
SK43796A3 (en) 1996-10-02
ES2142413T3 (es) 2000-04-16
FI961630A0 (fi) 1996-04-12
CZ106996A3 (en) 1996-09-11
DE69422724D1 (de) 2000-02-24
ZA947949B (en) 1996-01-23
SK282329B6 (sk) 2002-01-07
AU7855494A (en) 1995-05-04
DK0723546T3 (da) 2000-05-01
BG62405B1 (bg) 1999-10-29
BG100485A (bg) 1996-11-29
MY112110A (en) 2001-04-30
IL111259A (en) 1998-02-08
CA2173857A1 (en) 1995-04-20
CN1135754A (zh) 1996-11-13
PL177920B1 (pl) 2000-01-31
IL111259A0 (en) 1995-03-30
NO306509B1 (no) 1999-11-15
HUT74580A (en) 1997-01-28
DE69422724T2 (de) 2000-09-07
EP0723546A1 (en) 1996-07-31
NO961435L (no) 1996-06-10
AU679573B2 (en) 1997-07-03
EP0723546B1 (en) 2000-01-19
GB9321162D0 (en) 1993-12-01
GR3032480T3 (en) 2000-05-31
FI961630A7 (fi) 1996-04-12
IN179169B (enFirst) 1997-09-06
CN1040537C (zh) 1998-11-04
US5753665A (en) 1998-05-19
RO117020B1 (ro) 2001-09-28
RU2136684C1 (ru) 1999-09-10
JPH09503771A (ja) 1997-04-15
BR9407812A (pt) 1997-05-06
PL313970A1 (en) 1996-08-05

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