NZ237339A - Glycinamide derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
Glycinamide derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- NZ237339A NZ237339A NZ237339A NZ23733991A NZ237339A NZ 237339 A NZ237339 A NZ 237339A NZ 237339 A NZ237339 A NZ 237339A NZ 23733991 A NZ23733991 A NZ 23733991A NZ 237339 A NZ237339 A NZ 237339A
- Authority
- NZ
- New Zealand
- Prior art keywords
- quinolyl
- alk
- tert
- radical
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9002890A FR2659324B1 (fr) | 1990-03-07 | 1990-03-07 | N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant. |
FR9003838A FR2659966B1 (fr) | 1990-03-26 | 1990-03-26 | Derives de n-aralkyl glycinamide, leur preparation et les medicaments les contenant. |
FR9011651A FR2667066B2 (fr) | 1990-03-07 | 1990-09-21 | N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant. |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ237339A true NZ237339A (en) | 1992-10-28 |
Family
ID=27252167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ237339A NZ237339A (en) | 1990-03-07 | 1991-03-06 | Glycinamide derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0518961A1 (de) |
JP (1) | JPH05504968A (de) |
AU (1) | AU650261B2 (de) |
CA (1) | CA2074357A1 (de) |
HU (1) | HU210581B (de) |
IE (1) | IE910745A1 (de) |
IL (1) | IL97475A0 (de) |
NZ (1) | NZ237339A (de) |
PT (1) | PT96970A (de) |
WO (1) | WO1991013874A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658518B1 (fr) * | 1990-02-19 | 1992-04-30 | Rhone Poulenc Sante | N-phenyl n-alcoxycarbonylalkyle glycinamides, leur preparation et les medicaments les contenant. |
FR2695641B1 (fr) * | 1992-09-11 | 1994-11-25 | Rhone Poulenc Rorer Sa | (Amino-3 phényl)-1 éthanesulfonate d'hydroquinine optiquement actif, sa préparation et son utilisation. |
CN1141627A (zh) * | 1994-02-22 | 1997-01-29 | 默里尔药物公司 | 用于治疗雌激素相关肿瘤和疾病的新吲哚衍生物 |
FR2723739B1 (fr) * | 1994-08-19 | 1997-02-14 | Sanofi Sa | Derives de glycinamide, procedes pour leur preparation et medicaments les contenant. |
DK0832066T3 (da) | 1995-06-06 | 2001-11-19 | Pfizer | Substituerede N-(indol-2-carbonyl)amider og derivater som glycogenphosphorylaseinhibitorer |
ATE206702T1 (de) * | 1995-06-06 | 2001-10-15 | Pfizer | Substituierte n-(indol-2-carbonyl)-glycinamide und derivate als glycogen phosphorylase inhibitoren |
MY114711A (en) | 1995-06-06 | 2002-12-31 | Pfizer | Substituted n-(indole-2-carbonyl)-b-alanmamides and derivatives as antidiabetic agents |
US6696475B2 (en) | 1997-04-22 | 2004-02-24 | Neurosearch A/S | Substituted phenyl derivatives, their preparation and use |
BR9914638A (pt) | 1998-10-22 | 2001-07-03 | Neurosearch As | Composto, método para a preparação do mesmo, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio ou doença de um corpo de animal vivo |
US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
CA2476936A1 (en) * | 2002-02-20 | 2003-08-28 | Chih-Hung Lee | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor |
US7074805B2 (en) | 2002-02-20 | 2006-07-11 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US6933311B2 (en) | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
EP2054390B1 (de) | 2006-08-25 | 2012-04-11 | Abbott Laboratories | Indazolderivate zur hemmung von trpv1 und verwendungen davon |
JP2010513557A (ja) | 2006-12-20 | 2010-04-30 | アボット・ラボラトリーズ | 疼痛治療のためのtrpv1バニロイド受容体アンタゴニストとしてのn−(5,6,7,8−テトラヒドロナフタレン−1−イル)尿素誘導体および関連化合物 |
EP2489660A1 (de) | 2008-03-20 | 2012-08-22 | Abbott Laboratories | Verfahren zum Herstellen von Mitteln für das zentrale Nervensystem, die TRPV1-Antagonisten sind |
CN114181133B (zh) * | 2021-11-24 | 2023-04-28 | 上海应用技术大学 | 一种甘氨酸衍生乙酰胺化合物的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0166355A2 (de) * | 1984-06-26 | 1986-01-02 | Merck & Co. Inc. | Substituierte Aminophenyl- und Acylaminophenyl-Verbindungen und deren pharmazeutische Zusammensetzungen |
US4814463A (en) * | 1985-12-31 | 1989-03-21 | Biomeasure, Inc. | CCK antagonists |
FR2624698A1 (fr) * | 1987-12-18 | 1989-06-23 | Bernard Lyon I Universite Clau | Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-aminomalonyl ou aminosuccinyl amides utiles comme agents edulcorants |
EP0442878A4 (en) * | 1988-04-05 | 1991-10-23 | Abbott Laboratories | Derivatives of tryptophan as cck antagonists |
CA1326108C (en) * | 1988-04-12 | 1994-01-11 | Sun Hyuk Kim | Cck antagonists |
FR2658518B1 (fr) * | 1990-02-19 | 1992-04-30 | Rhone Poulenc Sante | N-phenyl n-alcoxycarbonylalkyle glycinamides, leur preparation et les medicaments les contenant. |
FR2667864B2 (fr) * | 1990-03-07 | 1994-08-05 | Rhone Poulenc Sante | Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant. |
-
1991
- 1991-03-05 CA CA002074357A patent/CA2074357A1/fr not_active Abandoned
- 1991-03-05 JP JP3505782A patent/JPH05504968A/ja active Pending
- 1991-03-05 AU AU74541/91A patent/AU650261B2/en not_active Ceased
- 1991-03-05 WO PCT/FR1991/000175 patent/WO1991013874A1/fr not_active Application Discontinuation
- 1991-03-05 HU HU9202864A patent/HU210581B/hu not_active IP Right Cessation
- 1991-03-05 EP EP91905834A patent/EP0518961A1/de not_active Withdrawn
- 1991-03-06 NZ NZ237339A patent/NZ237339A/en unknown
- 1991-03-06 IE IE074591A patent/IE910745A1/en unknown
- 1991-03-07 PT PT96970A patent/PT96970A/pt not_active Application Discontinuation
- 1991-03-07 IL IL97475A patent/IL97475A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HU210581B (en) | 1995-05-29 |
CA2074357A1 (fr) | 1991-09-08 |
EP0518961A1 (de) | 1992-12-23 |
IL97475A0 (en) | 1992-06-21 |
AU7454191A (en) | 1991-10-10 |
WO1991013874A1 (fr) | 1991-09-19 |
JPH05504968A (ja) | 1993-07-29 |
AU650261B2 (en) | 1994-06-16 |
HUT61731A (en) | 1993-03-01 |
IE910745A1 (en) | 1991-09-11 |
HU9202864D0 (en) | 1992-11-30 |
PT96970A (pt) | 1991-10-31 |
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