FR2667066B2 - N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant. - Google Patents

N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant.

Info

Publication number
FR2667066B2
FR2667066B2 FR9011651A FR9011651A FR2667066B2 FR 2667066 B2 FR2667066 B2 FR 2667066B2 FR 9011651 A FR9011651 A FR 9011651A FR 9011651 A FR9011651 A FR 9011651A FR 2667066 B2 FR2667066 B2 FR 2667066B2
Authority
FR
France
Prior art keywords
glycinamides
heterocyclyl
preparation
products containing
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9011651A
Other languages
English (en)
Other versions
FR2667066A2 (fr
Inventor
Bourzat Jean-Dominique
Capet Marc
Cotrel Claude
Guyon Claude
Manfre Franco
Roussel Gerard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9002890A external-priority patent/FR2659324B1/fr
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Priority to FR9011651A priority Critical patent/FR2667066B2/fr
Priority to CA002074357A priority patent/CA2074357A1/fr
Priority to AU74541/91A priority patent/AU650261B2/en
Priority to HU9202864A priority patent/HU210581B/hu
Priority to JP3505782A priority patent/JPH05504968A/ja
Priority to EP91905834A priority patent/EP0518961A1/fr
Priority to PCT/FR1991/000175 priority patent/WO1991013874A1/fr
Priority to IE074591A priority patent/IE910745A1/en
Priority to NZ237339A priority patent/NZ237339A/en
Priority to IL97475A priority patent/IL97475A0/xx
Priority to PT96970A priority patent/PT96970A/pt
Publication of FR2667066A2 publication Critical patent/FR2667066A2/fr
Priority to NO923457A priority patent/NO923457D0/no
Publication of FR2667066B2 publication Critical patent/FR2667066B2/fr
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9011651A 1990-03-07 1990-09-21 N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant. Expired - Lifetime FR2667066B2 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR9011651A FR2667066B2 (fr) 1990-03-07 1990-09-21 N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant.
PCT/FR1991/000175 WO1991013874A1 (fr) 1990-03-07 1991-03-05 Derives de glycinamide, leur preparation et les medicaments les contenant
AU74541/91A AU650261B2 (en) 1990-03-07 1991-03-05 Derivatives of glycinamide, their preparation and medicaments containing them
HU9202864A HU210581B (en) 1990-03-07 1991-03-05 Process for prep. of glycinamide deriv.s and pharmaceutical compn.s contg. them
JP3505782A JPH05504968A (ja) 1990-03-07 1991-03-05 グリシンアミド誘導体、その製造及びそれを含む医薬品
EP91905834A EP0518961A1 (fr) 1990-03-07 1991-03-05 Derives de glycinamide, leur preparation et les medicaments les contenant
CA002074357A CA2074357A1 (fr) 1990-03-07 1991-03-05 Derives de glycinamide, leur preparation et les medicaments les contenant
NZ237339A NZ237339A (en) 1990-03-07 1991-03-06 Glycinamide derivatives, their preparation and pharmaceutical compositions containing them
IE074591A IE910745A1 (en) 1990-03-07 1991-03-06 Glycinamide derivatives, their preparation, pharmaceutical¹compositions containing them, and their use
IL97475A IL97475A0 (en) 1990-03-07 1991-03-07 Glycinamide derivatives,their preparation,pharmaceutical compositions containing them,and their application
PT96970A PT96970A (pt) 1990-03-07 1991-03-07 Processo de preparacao de derivados da glicinamida e de composicoes farmaceuticas que os contem
NO923457A NO923457D0 (no) 1990-03-07 1992-09-04 Glycinamidderivater, deres fremstilling og medikamenter inneholdende derivatene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9002890A FR2659324B1 (fr) 1990-03-07 1990-03-07 N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant.
FR9011651A FR2667066B2 (fr) 1990-03-07 1990-09-21 N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant.

Publications (2)

Publication Number Publication Date
FR2667066A2 FR2667066A2 (fr) 1992-03-27
FR2667066B2 true FR2667066B2 (fr) 1993-06-25

Family

ID=26227912

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9011651A Expired - Lifetime FR2667066B2 (fr) 1990-03-07 1990-09-21 N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant.

Country Status (1)

Country Link
FR (1) FR2667066B2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166355A2 (fr) * 1984-06-26 1986-01-02 Merck & Co. Inc. Composés aminophényle et acylaminophényle substitués et les compositions pharmaceutiques les contenant
US4814463A (en) * 1985-12-31 1989-03-21 Biomeasure, Inc. CCK antagonists
EP0336356A3 (fr) * 1988-04-05 1991-09-25 Abbott Laboratories Dérivés du tryptophane antagonistes des CCK

Also Published As

Publication number Publication date
FR2667066A2 (fr) 1992-03-27

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