NZ207959A - 4s-6-fluoro- 8-(deutero, tritio or halo)-spiro(chroman -4,4'-imidazoline)-2',5'-diones - Google Patents

4s-6-fluoro- 8-(deutero, tritio or halo)-spiro(chroman -4,4'-imidazoline)-2',5'-diones

Info

Publication number
NZ207959A
NZ207959A NZ207959A NZ20795984A NZ207959A NZ 207959 A NZ207959 A NZ 207959A NZ 207959 A NZ207959 A NZ 207959A NZ 20795984 A NZ20795984 A NZ 20795984A NZ 207959 A NZ207959 A NZ 207959A
Authority
NZ
New Zealand
Prior art keywords
spiro
chroman
fluoro
imidazolidine
dione
Prior art date
Application number
NZ207959A
Other languages
English (en)
Inventor
R Sarges
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NZ207959A publication Critical patent/NZ207959A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NZ207959A 1983-04-27 1984-04-26 4s-6-fluoro- 8-(deutero, tritio or halo)-spiro(chroman -4,4'-imidazoline)-2',5'-diones NZ207959A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/488,947 US4474967A (en) 1983-04-27 1983-04-27 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione

Publications (1)

Publication Number Publication Date
NZ207959A true NZ207959A (en) 1987-04-30

Family

ID=23941785

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ207959A NZ207959A (en) 1983-04-27 1984-04-26 4s-6-fluoro- 8-(deutero, tritio or halo)-spiro(chroman -4,4'-imidazoline)-2',5'-diones

Country Status (22)

Country Link
US (1) US4474967A (en, 2012)
EP (1) EP0124327A3 (en, 2012)
JP (1) JPS59205384A (en, 2012)
KR (1) KR860000915B1 (en, 2012)
AU (1) AU542142B2 (en, 2012)
CA (1) CA1226866A (en, 2012)
CS (1) CS250661B2 (en, 2012)
DD (1) DD219772A5 (en, 2012)
DK (1) DK208284A (en, 2012)
ES (1) ES8607312A1 (en, 2012)
FI (1) FI841657L (en, 2012)
GR (1) GR81491B (en, 2012)
HU (1) HU191755B (en, 2012)
IL (1) IL71656A (en, 2012)
NO (1) NO841627L (en, 2012)
NZ (1) NZ207959A (en, 2012)
PH (1) PH22869A (en, 2012)
PL (1) PL142759B1 (en, 2012)
PT (1) PT78476B (en, 2012)
SU (1) SU1240362A3 (en, 2012)
YU (1) YU43358B (en, 2012)
ZA (1) ZA843091B (en, 2012)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3565105D1 (en) * 1984-08-20 1988-10-27 Pfizer Process for the production as asymmetric hydantoins
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides
GB9317764D0 (en) * 1993-08-26 1993-10-13 Pfizer Ltd Therapeutic compound
AU2184499A (en) * 1998-01-30 1999-08-16 R-Tech Ueno, Ltd. Ophthalmic composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation

Also Published As

Publication number Publication date
NO841627L (no) 1984-10-29
YU43358B (en) 1989-06-30
JPS59205384A (ja) 1984-11-20
PL247379A1 (en) 1985-03-26
CA1226866A (en) 1987-09-15
DK208284D0 (da) 1984-04-26
HUT34197A (en) 1985-02-28
DK208284A (da) 1984-10-28
PL142759B1 (en) 1987-11-30
PT78476B (en) 1986-08-28
CS250661B2 (en) 1987-05-14
IL71656A0 (en) 1984-07-31
FI841657A7 (fi) 1984-10-28
IL71656A (en) 1987-10-20
PT78476A (en) 1984-05-01
PH22869A (en) 1989-01-19
EP0124327A2 (en) 1984-11-07
EP0124327A3 (en) 1985-07-31
FI841657A0 (fi) 1984-04-26
GR81491B (en, 2012) 1984-12-11
HU191755B (en) 1987-04-28
ZA843091B (en) 1985-12-24
KR840008355A (ko) 1984-12-14
US4474967A (en) 1984-10-02
FI841657L (fi) 1984-10-28
ES531873A0 (es) 1986-06-01
SU1240362A3 (ru) 1986-06-23
ES8607312A1 (es) 1986-06-01
KR860000915B1 (ko) 1986-07-18
AU2726384A (en) 1984-11-01
AU542142B2 (en) 1985-02-07
YU74184A (en) 1986-10-31
DD219772A5 (de) 1985-03-13

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