NZ207091A - Substituted benzazepinones and pharmaceutical compositions - Google Patents
Substituted benzazepinones and pharmaceutical compositionsInfo
- Publication number
- NZ207091A NZ207091A NZ207091A NZ20709184A NZ207091A NZ 207091 A NZ207091 A NZ 207091A NZ 207091 A NZ207091 A NZ 207091A NZ 20709184 A NZ20709184 A NZ 20709184A NZ 207091 A NZ207091 A NZ 207091A
- Authority
- NZ
- New Zealand
- Prior art keywords
- formula
- compound
- cor
- hydroxy
- benzazepin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/465,695 US4473575A (en) | 1982-07-19 | 1983-02-10 | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ207091A true NZ207091A (en) | 1985-11-08 |
Family
ID=23848805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ207091A NZ207091A (en) | 1983-02-10 | 1984-02-09 | Substituted benzazepinones and pharmaceutical compositions |
Country Status (24)
Country | Link |
---|---|
US (1) | US4473575A (zh-CN) |
EP (2) | EP0119954B1 (zh-CN) |
JP (2) | JPS59172473A (zh-CN) |
KR (1) | KR900009023B1 (zh-CN) |
AR (8) | AR242564A1 (zh-CN) |
AT (2) | ATE48598T1 (zh-CN) |
AU (1) | AU574061B2 (zh-CN) |
CA (2) | CA1225397A (zh-CN) |
CY (1) | CY1674A (zh-CN) |
DD (1) | DD218359A5 (zh-CN) |
DE (2) | DE3480705D1 (zh-CN) |
DK (2) | DK171257B1 (zh-CN) |
ES (10) | ES8609261A1 (zh-CN) |
FI (1) | FI77857C (zh-CN) |
GR (1) | GR79809B (zh-CN) |
HK (1) | HK97592A (zh-CN) |
HU (1) | HU192394B (zh-CN) |
IE (1) | IE56858B1 (zh-CN) |
IL (1) | IL70881A (zh-CN) |
NO (1) | NO166232C (zh-CN) |
NZ (1) | NZ207091A (zh-CN) |
PT (1) | PT78075B (zh-CN) |
SG (1) | SG94992G (zh-CN) |
ZA (1) | ZA84958B (zh-CN) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4473575A (en) * | 1982-07-19 | 1984-09-25 | Ciba-Geigy Corporation | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
US4575503A (en) * | 1983-02-10 | 1986-03-11 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
US4537885A (en) * | 1983-02-10 | 1985-08-27 | Ciba Geigy Corporation | Certain benzazocinone and benzazoninone derivatives |
US4600534A (en) * | 1984-02-06 | 1986-07-15 | Ciba-Geigy Corporation | Process and intermediates for manufacture of 3-(5-amino-1-carboxypentylamino)-tetrahydro-1-benzazepin-2-one-1-acetic acid |
DE3586445T2 (de) * | 1984-06-26 | 1993-01-14 | Merck & Co Inc | Kondensierte benzo-laktam-verbindungen und deren pharmazeutische zusammensetzungen. |
EP0166357A3 (en) * | 1984-06-26 | 1988-10-26 | Merck & Co. Inc. | Benzofused lactams and pharmaceutical compositions containing them |
US4692522A (en) * | 1985-04-01 | 1987-09-08 | Merck & Co., Inc. | Benzofused lactams useful as cholecystokinin antagonists |
US4785089A (en) * | 1985-06-13 | 1988-11-15 | Ciba-Geigy Corporation | Novel sulfonic acid esters and their preparation |
EP0237267B1 (en) * | 1986-03-11 | 1991-01-23 | Barry Anthony Thompson | Feeding livestock with polymers |
AT399717B (de) * | 1986-05-28 | 1995-07-25 | Ciba Geigy Ag | Verfahren zur herstellung von (2,5-dihydro-2-oxo- 5-phenyl-3-furanyl)aminen |
US4918187A (en) * | 1986-05-28 | 1990-04-17 | Ciba-Geigy Corporation | [2,5-Dihydro 5-phenyl-2-oxo-3-furanyl]amines |
FI88723C (fi) * | 1986-05-28 | 1993-06-28 | Ciba Geigy Ag | /2,5-dihydro-2-oxo-5-fenyl-3-furanyl/aminer samt deras anvaendning vid framstaellning av ACE-inhibitorer |
US5028704A (en) * | 1986-05-28 | 1991-07-02 | Ciba-Geigy Corporation | (2,5-dihydro 5-phenyl-2-oxo-3-furanyl)amines, methods of manufacture, and use thereof in the production of angiotensin converting enzyme inhibitors |
US4962105A (en) | 1987-10-19 | 1990-10-09 | Ciba-Geigy Corporation | Potentiation of antihypertensive effect of ace inhibitors |
JPH07116224B2 (ja) * | 1987-12-29 | 1995-12-13 | 吉富製薬株式会社 | ベンゾラクタム化合物 |
GB9100028D0 (en) * | 1991-01-02 | 1991-02-20 | Ici Plc | Compounds |
US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
US5552397A (en) * | 1992-05-18 | 1996-09-03 | E. R. Squibb & Sons, Inc. | Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase |
RU2124503C1 (ru) | 1992-05-18 | 1999-01-10 | И.Р.Сквибб энд Санз, Инк. | Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция |
GB9212308D0 (en) * | 1992-06-10 | 1992-07-22 | Ici Plc | Therapeutic compositions |
US5654294A (en) * | 1993-05-13 | 1997-08-05 | Bristol-Myers Squibb | Spiro lactam dual action inhibitors |
GB9311948D0 (en) * | 1993-06-10 | 1993-07-28 | Zeneca Ltd | Substituted nitrogen heterocycles |
ES2162907T3 (es) * | 1993-11-22 | 2002-01-16 | Merck & Co Inc | 3-acilaminobenzacepinas. |
US5801168A (en) * | 1994-06-09 | 1998-09-01 | Zeneca Limited | Substituted nitrogen heterocycles |
DK0776208T3 (da) * | 1994-08-18 | 2000-05-01 | Merck & Co Inc | 2,3-dihydro-1-(2,2,2-trifluorethyl)-2-oxo-5-phenyl-1H-1,4-benzodiazepiner |
US5587375A (en) * | 1995-02-17 | 1996-12-24 | Bristol-Myers Squibb Company | Azepinone compounds useful in the inhibition of ACE and NEP |
US5877313A (en) * | 1995-05-17 | 1999-03-02 | Bristol-Myers Squibb | Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP |
US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
US5635504A (en) * | 1995-06-07 | 1997-06-03 | Bristol-Myers Squibb Co. | Diazepine containing dual action inhibitors |
CA2222491A1 (en) * | 1995-06-07 | 1996-12-19 | Merck & Co., Inc. | Novel n-(2,4-dioxo-2,3,4,5-tetrahydro-1h-1,5-benzodiazepin-3yl)-3-amides |
US5650408A (en) * | 1995-06-07 | 1997-07-22 | Karanewsky; Donald S. | Thiazolo benzazepine containing dual action inhibitors |
US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
US6191166B1 (en) | 1997-11-21 | 2001-02-20 | Elan Pharmaceuticals, Inc. | Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis |
US6211235B1 (en) | 1996-11-22 | 2001-04-03 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting β-amyloid peptide release and/or its synthesis |
US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6683075B1 (en) | 1996-12-23 | 2004-01-27 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use |
JP2002241368A (ja) * | 1997-02-18 | 2002-08-28 | Shionogi & Co Ltd | 新規ベンゾラクタム誘導体およびそれを含有する医薬組成物 |
WO1998041510A1 (fr) * | 1997-03-14 | 1998-09-24 | Shionogi & Co., Ltd. | Nouveaux derives du benzolactame et compositions medicamenteuses les contenant |
US6569851B1 (en) | 1998-06-22 | 2003-05-27 | Elan Pharmaceutials, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6509331B1 (en) | 1998-06-22 | 2003-01-21 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6528505B1 (en) | 1998-06-22 | 2003-03-04 | Elan Pharmaceuticals, Inc. | Cyclic amino acid compounds pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6774125B2 (en) * | 1998-06-22 | 2004-08-10 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6552013B1 (en) | 1998-06-22 | 2003-04-22 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
WO2001035964A1 (en) * | 1999-11-18 | 2001-05-25 | Antexpharma, Inc. | Substituted 1-benzazepines and derivatives thereof |
US7795468B2 (en) * | 2001-01-19 | 2010-09-14 | Chevron U.S.A. Inc. | Functionalized higher diamondoids |
US6984645B2 (en) * | 2001-11-16 | 2006-01-10 | Bristol-Myers Squibb Company | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein |
US20050192265A1 (en) * | 2003-03-20 | 2005-09-01 | Thompson Richard C. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds |
US20050203168A1 (en) * | 2004-03-11 | 2005-09-15 | The Regents Of The University Of Michigan | Angiotensin converting enzyme inhibitor use for treatment and prevention of gastrointestinal disorders |
US8080579B2 (en) * | 2005-10-03 | 2011-12-20 | The Regents Of The University Of Michigan | Compositions and methods for treatment of inflammatory bowel disease |
US7592461B2 (en) | 2005-12-21 | 2009-09-22 | Bristol-Myers Squibb Company | Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
US20070238770A1 (en) * | 2006-04-05 | 2007-10-11 | Bristol-Myers Squibb Company | Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations |
CN101573340A (zh) | 2006-11-01 | 2009-11-04 | 百时美施贵宝公司 | 糖皮质激素受体AP-1和/或NF-κB活性的调节剂及其用途 |
EP2089355A2 (en) | 2006-11-01 | 2009-08-19 | Brystol-Myers Squibb Company | Modulators of glucocorticoid receptor, ap-1, and/or nf- kappa b activity and use thereof |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US7828840B2 (en) * | 2007-11-15 | 2010-11-09 | Med Institute, Inc. | Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists |
EP2328910B1 (en) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
JP2011525537A (ja) | 2008-06-24 | 2011-09-22 | ブリストル−マイヤーズ スクイブ カンパニー | グルココルチコイド受容体、AP−1、および/またはNF−κB活性のシクロペンタチオフェン調節剤およびその使用 |
EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
BR112015030326A2 (pt) | 2013-06-05 | 2017-08-29 | Synergy Pharmaceuticals Inc | Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos |
US9593113B2 (en) | 2013-08-22 | 2017-03-14 | Bristol-Myers Squibb Company | Imide and acylurea derivatives as modulators of the glucocorticoid receptor |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3330823A (en) * | 1964-12-16 | 1967-07-11 | Squibb & Sons Inc | N-amino-loweralkylene-benzo-lactams |
US3395150A (en) * | 1965-02-26 | 1968-07-30 | Squibb & Sons Inc | Benzothiazepine carboxamides and derivatives thereof |
GB1305278A (zh-CN) * | 1970-03-12 | 1973-01-31 | ||
JPS5129522B2 (zh-CN) * | 1972-07-13 | 1976-08-26 | ||
JPS5520970B2 (zh-CN) * | 1972-07-15 | 1980-06-06 | ||
FR2358151A1 (fr) * | 1976-03-31 | 1978-02-10 | Roussel Uclaf | Nouvelles benzazepines et leurs sels, procede de preparation et application a titre de medicaments |
IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
US4377515A (en) * | 1979-10-01 | 1983-03-22 | Merck & Co., Inc. | Long lasting agonists and antagonists of LH-RH |
GR74635B (zh-CN) * | 1980-08-18 | 1984-06-29 | Merck & Co Inc | |
US4409146A (en) * | 1980-10-06 | 1983-10-11 | Merck & Co., Inc. | Substituted caprolactam derivatives as antihypertensives |
IN156096B (zh-CN) * | 1981-03-19 | 1985-05-11 | Usv Pharma Corp | |
US4415496A (en) * | 1981-03-23 | 1983-11-15 | Merck & Co., Inc. | Bicyclic lactams |
GB2103614B (en) * | 1981-08-11 | 1984-11-21 | Ciba Geigy Ag | Benzazepin-2-ones |
ZA825779B (en) * | 1981-08-11 | 1984-04-25 | Ciba Geigy Ag | Benzazepins-2-ones |
US4410520A (en) * | 1981-11-09 | 1983-10-18 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
US4473575A (en) * | 1982-07-19 | 1984-09-25 | Ciba-Geigy Corporation | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
DE3373469D1 (en) * | 1982-09-30 | 1987-10-15 | Merck & Co Inc | 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents |
-
1983
- 1983-02-10 US US06/465,695 patent/US4473575A/en not_active Expired - Lifetime
-
1984
- 1984-02-06 EP EP84810071A patent/EP0119954B1/de not_active Expired - Lifetime
- 1984-02-06 AT AT84810072T patent/ATE48598T1/de active
- 1984-02-06 AT AT84810071T patent/ATE50989T1/de active
- 1984-02-06 DE DE8484810072T patent/DE3480705D1/de not_active Expired - Lifetime
- 1984-02-06 EP EP84810072A patent/EP0119955B1/de not_active Expired
- 1984-02-06 DE DE8484810071T patent/DE3481612D1/de not_active Expired - Lifetime
- 1984-02-07 IL IL70881A patent/IL70881A/xx not_active IP Right Cessation
- 1984-02-08 GR GR73754A patent/GR79809B/el unknown
- 1984-02-08 FI FI840513A patent/FI77857C/fi not_active IP Right Cessation
- 1984-02-08 CA CA000446971A patent/CA1225397A/en not_active Expired
- 1984-02-08 PT PT78075A patent/PT78075B/pt not_active IP Right Cessation
- 1984-02-08 CA CA000446970A patent/CA1218993A/en not_active Expired
- 1984-02-09 IE IE302/84A patent/IE56858B1/en not_active IP Right Cessation
- 1984-02-09 ZA ZA84958A patent/ZA84958B/xx unknown
- 1984-02-09 AU AU24430/84A patent/AU574061B2/en not_active Ceased
- 1984-02-09 JP JP59020905A patent/JPS59172473A/ja active Granted
- 1984-02-09 NO NO840487A patent/NO166232C/no unknown
- 1984-02-09 HU HU84523A patent/HU192394B/hu not_active IP Right Cessation
- 1984-02-09 ES ES529594A patent/ES8609261A1/es not_active Expired
- 1984-02-09 DK DK058284A patent/DK171257B1/da not_active IP Right Cessation
- 1984-02-09 DK DK58184A patent/DK58184A/da not_active Application Discontinuation
- 1984-02-09 NZ NZ207091A patent/NZ207091A/en unknown
- 1984-02-09 ES ES529595A patent/ES8707216A1/es not_active Expired
- 1984-02-09 DD DD84259979A patent/DD218359A5/de not_active IP Right Cessation
- 1984-02-10 KR KR1019840000630A patent/KR900009023B1/ko not_active IP Right Cessation
- 1984-02-10 AR AR84295689A patent/AR242564A1/es active
- 1984-02-10 JP JP59022031A patent/JPS59172475A/ja active Granted
-
1985
- 1985-06-13 ES ES544127A patent/ES8702363A1/es not_active Expired
- 1985-06-17 ES ES544258A patent/ES8609264A1/es not_active Expired
- 1985-06-17 ES ES544254A patent/ES8703859A1/es not_active Expired
- 1985-06-17 ES ES544255A patent/ES8609262A1/es not_active Expired
- 1985-06-17 ES ES544256A patent/ES8705409A1/es not_active Expired
- 1985-06-17 ES ES544259A patent/ES8700239A1/es not_active Expired
- 1985-06-17 ES ES544260A patent/ES8609265A1/es not_active Expired
- 1985-06-17 ES ES544257A patent/ES8609263A1/es not_active Expired
-
1986
- 1986-08-15 AR AR86304925A patent/AR243162A1/es active
- 1986-08-15 AR AR86304921A patent/AR242191A1/es active
- 1986-08-15 AR AR86304923A patent/AR243164A1/es active
- 1986-08-15 AR AR86304926A patent/AR243161A1/es active
- 1986-08-15 AR AR86304922A patent/AR243165A1/es active
- 1986-08-15 AR AR86304920A patent/AR242190A1/es active
- 1986-08-15 AR AR86304924A patent/AR243163A1/es active
-
1992
- 1992-09-21 SG SG949/92A patent/SG94992G/en unknown
- 1992-12-03 HK HK975/92A patent/HK97592A/xx not_active IP Right Cessation
-
1993
- 1993-10-10 CY CY1674A patent/CY1674A/xx unknown
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