NO996453L - Nye tricykliske forbindelser med mettede ringer, samt medisinske blandinger inneholdende forbindelsene - Google Patents
Nye tricykliske forbindelser med mettede ringer, samt medisinske blandinger inneholdende forbindelseneInfo
- Publication number
- NO996453L NO996453L NO996453A NO996453A NO996453L NO 996453 L NO996453 L NO 996453L NO 996453 A NO996453 A NO 996453A NO 996453 A NO996453 A NO 996453A NO 996453 L NO996453 L NO 996453L
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen atom
- compounds
- atom
- amino
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Forbindelser som representeres ved den generelle formel (I), eller salter derav: hvor R representerer et hydrogenatom eller metyl, R1 betyr et hydrogenatom, halogenatom, hydroksy, benzyloksy, amino eller hydroksymetyl, R2 betyr et hydrogenatom, hydroksy- metyl, NHR3, SO2NR4R4' eller nitro, hvor R1 er et hydrogen- atom, metyl, SO2R5, formyl eller CONHRS|, med R5 er lavere alkyl, benzyl eller NR4R4', og 4 og R4' kan være identiske eller forskjellige fra hverandre for et hydrogenatom, lavere alkyl eller benzyl, RS| representerer et hydrogen- atom eller lavere alkyl, og Rs representerer et hydrogen- atom eller lavere alkyl, n er l eller 2, og X er et sekun- dært nitrogenatom, oksygenatom eller svovelatom og, i til- felle at n er l, betyr en av R7 og R8 er et hydrogenatom og den andre er et hydrogenatom, amino, acetylamino eller hyd- roksy, eller, i tilfelle at n er 2, er R8 et hydrogenatom og R7 er et hydrogenatom, amino, acetyl amino eller hyd- roksy, og *1 betyr et usymmetrisk karbonatom og *2 og *3 viser at karbonatomet er asymmetrisk, forutsatt at R' og R8 ikke betyr et hydrogenatom. Forbindelsene er terapeutisk aktive.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17819797 | 1997-07-03 | ||
PCT/JP1998/002680 WO1999001431A1 (fr) | 1997-07-03 | 1998-06-17 | Nouveaux composes tricycliques presentant des noyaux satures et compositions medicinales les contenant |
Publications (2)
Publication Number | Publication Date |
---|---|
NO996453D0 NO996453D0 (no) | 1999-12-23 |
NO996453L true NO996453L (no) | 2000-03-03 |
Family
ID=16044289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO996453A NO996453L (no) | 1997-07-03 | 1999-12-23 | Nye tricykliske forbindelser med mettede ringer, samt medisinske blandinger inneholdende forbindelsene |
Country Status (9)
Country | Link |
---|---|
US (1) | US6172099B1 (no) |
EP (1) | EP0997458A4 (no) |
KR (1) | KR100335169B1 (no) |
AU (1) | AU735249B2 (no) |
CA (1) | CA2296104A1 (no) |
DE (1) | DE997458T1 (no) |
ES (1) | ES2149742T1 (no) |
NO (1) | NO996453L (no) |
WO (1) | WO1999001431A1 (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA01001111A (es) | 1998-08-04 | 2002-04-24 | Metabolix Inc | Produccion de polihidroxialcanoato a partir de polioles. |
TW519537B (en) * | 1999-03-26 | 2003-02-01 | Asahi Chemical Ind | Process for the preparation of tricylic amino-alcohol derivatives |
AU3325900A (en) * | 1999-04-01 | 2000-10-23 | Asahi Kasei Kabushiki Kaisha | Method for the preparation of tricyclic amino alcohol derivatives through azides |
WO2001004092A1 (fr) * | 1999-07-09 | 2001-01-18 | Asahi Kasei Kabushiki Kaisha | Procede de preparation de derives d'alcools amines tricycliques |
CN1377342A (zh) * | 1999-09-03 | 2002-10-30 | 旭化成株式会社 | 三环氨基醇衍生物的制备方法 |
MXPA02003423A (es) * | 1999-10-04 | 2002-08-20 | Ashai Kasei Kabushiki Kaisha | Metodo para mejorar la solubilidad de los derivados de aminoalcoholes triciclicos. |
KR20020069215A (ko) * | 1999-12-16 | 2002-08-29 | 아사히 가세이 가부시키가이샤 | 신규한 치환기를 갖는 3환성 화합물 |
AU2710301A (en) * | 2000-01-28 | 2001-08-07 | Asahi Kasei Kabushiki Kaisha | Novel remedies with the use of beta3 agonist |
ATE369337T1 (de) * | 2000-04-28 | 2007-08-15 | Asahi Kasei Pharma Corp | Neue bizyklische verbindungen |
GB0010757D0 (en) | 2000-05-05 | 2000-06-28 | Astrazeneca Ab | Chemical compounds |
GB0029562D0 (en) * | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
WO2002074306A1 (fr) * | 2001-03-19 | 2002-09-26 | Asahi Kasei Kabushiki Kaisha | Remedes pour la steatose hepatique |
US20050020632A1 (en) * | 2001-08-31 | 2005-01-27 | Dominique Grimler | Optical isomers of an iloperidone metabolite |
GB0121941D0 (en) | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
CN100347158C (zh) * | 2001-10-25 | 2007-11-07 | 旭化成制药株式会社 | 二环化合物 |
AU2009301798B2 (en) | 2008-10-09 | 2012-03-01 | Asahi Kasei Pharma Corporation | Indazole compound |
AU2009301797B2 (en) | 2008-10-09 | 2012-03-01 | Asahi Kasei Pharma Corporation | Indazole derivative |
US20100222404A1 (en) * | 2008-11-04 | 2010-09-02 | Asahi Kasei Pharma Corporation | Indazole derivative dihydrochloride |
ES2394349B1 (es) | 2012-08-29 | 2013-11-04 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2332010A1 (fr) | 1975-11-18 | 1977-06-17 | Continental Pharma | Amino-alcool heterocyclique, son sel et son procede de preparation |
JPS5553262A (en) | 1978-10-17 | 1980-04-18 | Yamanouchi Pharmaceut Co Ltd | Phenylethanolamine derivative |
EP0023385B1 (en) | 1979-06-16 | 1982-12-15 | Beecham Group Plc | Ethanamine derivatives, their preparation and use in pharmaceutical compositions |
JPS5950671B2 (ja) | 1982-08-26 | 1984-12-10 | 山之内製薬株式会社 | フェニルエタノ−ルアミン誘導体およびその製造法 |
JPS6016980A (ja) * | 1983-07-06 | 1985-01-28 | Nippon Soda Co Ltd | ヘキサヒドロジベンゾフラン誘導体及びその製造方法 |
GB8419797D0 (en) | 1984-08-03 | 1984-09-05 | Beecham Group Plc | Compounds |
GB8926083D0 (en) | 1989-11-17 | 1990-01-10 | Ici Plc | Therapeutic agents |
US5061727A (en) | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
US5100891A (en) * | 1991-01-18 | 1992-03-31 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds |
PL312005A1 (en) * | 1993-06-14 | 1996-04-01 | Pfizer | Binary amines as antidiabetic and antiobesitic agents |
US5776983A (en) | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
US5541197A (en) | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
JPH08165276A (ja) | 1994-12-14 | 1996-06-25 | Dainippon Pharmaceut Co Ltd | 2−アルキルアミノ−1−フェニルエタノール誘導体 |
JPH11504648A (ja) * | 1995-05-10 | 1999-04-27 | ファイザー・インコーポレーテッド | β−アドレナリン作動性アゴニスト |
WO1997025311A1 (fr) * | 1996-01-10 | 1997-07-17 | Asahi Kasei Kogyo Kabushiki Kaisha | Nouveaux composes tricycliques et compositions medicamenteuses contenant ces composes |
AU4221697A (en) * | 1996-09-20 | 1998-04-14 | Yamanouchi Pharmaceutical Co., Ltd. | Novel tricyclic fused ring derivatives |
-
1998
- 1998-06-17 CA CA002296104A patent/CA2296104A1/en not_active Abandoned
- 1998-06-17 ES ES98928532T patent/ES2149742T1/es active Pending
- 1998-06-17 EP EP98928532A patent/EP0997458A4/en not_active Withdrawn
- 1998-06-17 AU AU80334/98A patent/AU735249B2/en not_active Ceased
- 1998-06-17 KR KR1020007000008A patent/KR100335169B1/ko not_active IP Right Cessation
- 1998-06-17 US US09/446,515 patent/US6172099B1/en not_active Expired - Fee Related
- 1998-06-17 WO PCT/JP1998/002680 patent/WO1999001431A1/ja not_active Application Discontinuation
- 1998-06-17 DE DE0997458T patent/DE997458T1/de active Pending
-
1999
- 1999-12-23 NO NO996453A patent/NO996453L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2296104A1 (en) | 1999-01-14 |
US6172099B1 (en) | 2001-01-09 |
WO1999001431A1 (fr) | 1999-01-14 |
ES2149742T1 (es) | 2000-11-16 |
AU735249B2 (en) | 2001-07-05 |
AU8033498A (en) | 1999-01-25 |
EP0997458A4 (en) | 2003-03-05 |
NO996453D0 (no) | 1999-12-23 |
KR20010015528A (ko) | 2001-02-26 |
EP0997458A1 (en) | 2000-05-03 |
KR100335169B1 (ko) | 2002-05-04 |
DE997458T1 (de) | 2001-03-01 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |