NO992895D0 - Indan- eller dihydroindolderivater - Google Patents

Indan- eller dihydroindolderivater

Info

Publication number
NO992895D0
NO992895D0 NO992895A NO992895A NO992895D0 NO 992895 D0 NO992895 D0 NO 992895D0 NO 992895 A NO992895 A NO 992895A NO 992895 A NO992895 A NO 992895A NO 992895 D0 NO992895 D0 NO 992895D0
Authority
NO
Norway
Prior art keywords
indane
dihydroindole derivatives
dihydroindole
derivatives
Prior art date
Application number
NO992895A
Other languages
English (en)
Other versions
NO318978B1 (no
NO992895L (no
Inventor
Jens Kristian Perregaard
Benny Bang-Andersen
Henrik Pedersen
Ivan Mikkelsen
Robert Dancer
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO992895D0 publication Critical patent/NO992895D0/no
Publication of NO992895L publication Critical patent/NO992895L/no
Publication of NO318978B1 publication Critical patent/NO318978B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C5/00Details of stores covered by group G11C11/00
    • G11C5/02Disposition of storage elements, e.g. in the form of a matrix array
    • G11C5/025Geometric lay-out considerations of storage- and peripheral-blocks in a semiconductor storage device
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C7/00Arrangements for writing information into, or reading information out from, a digital store
    • G11C7/10Input/output [I/O] data interface arrangements, e.g. I/O data control circuits, I/O data buffers
    • G11C7/1048Data bus control circuits, e.g. precharging, presetting, equalising
NO19992895A 1996-12-20 1999-06-14 Substituerte dihydroindolderivater, farmasoytiske sammensetninger inneholdende dem og deres anvendelse. NO318978B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK151496 1996-12-20
PCT/DK1997/000587 WO1998028293A1 (en) 1996-12-20 1997-12-19 Indane or dihydroindole derivatives

Publications (3)

Publication Number Publication Date
NO992895D0 true NO992895D0 (no) 1999-06-14
NO992895L NO992895L (no) 1999-08-13
NO318978B1 NO318978B1 (no) 2005-05-30

Family

ID=8105631

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19992895A NO318978B1 (no) 1996-12-20 1999-06-14 Substituerte dihydroindolderivater, farmasoytiske sammensetninger inneholdende dem og deres anvendelse.
NO20044514A NO20044514L (no) 1996-12-20 2004-10-21 Indan- eller dihydroindolderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20044514A NO20044514L (no) 1996-12-20 2004-10-21 Indan- eller dihydroindolderivater

Country Status (28)

Country Link
US (3) US6262087B1 (no)
EP (1) EP0946542B1 (no)
JP (1) JP3251300B2 (no)
KR (1) KR100432297B1 (no)
CN (3) CN1146556C (no)
AR (1) AR008545A1 (no)
AT (1) ATE225784T1 (no)
AU (1) AU731243B2 (no)
BG (1) BG63968B1 (no)
BR (1) BR9714039A (no)
CZ (1) CZ297416B6 (no)
DE (1) DE69716296T2 (no)
DK (1) DK0946542T3 (no)
EA (1) EA002158B1 (no)
ES (1) ES2185058T3 (no)
HK (1) HK1025775A1 (no)
HU (1) HUP0000079A3 (no)
IL (1) IL130133A (no)
IS (1) IS2018B (no)
NO (2) NO318978B1 (no)
NZ (1) NZ335973A (no)
PL (1) PL188418B1 (no)
PT (1) PT946542E (no)
SK (1) SK283678B6 (no)
TR (1) TR199901407T2 (no)
UA (1) UA66778C2 (no)
WO (1) WO1998028293A1 (no)
ZA (1) ZA9711376B (no)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
TWI242011B (en) * 1997-03-31 2005-10-21 Eisai Co Ltd 1,4-substituted cyclic amine derivatives
PT1068199E (pt) * 1998-04-08 2003-02-28 Wyeth Corp N-ariloxietil-indoli-alquilaminas para o tratamento da depressao
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
TW528754B (en) * 1998-04-29 2003-04-21 Wyeth Corp Indolyl derivatibes as serotonergic agents
US6204274B1 (en) 1998-04-29 2001-03-20 American Home Products Corporation Indolyl derivatives as serotonergic agents
US6362371B1 (en) * 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
EP1083918A1 (en) * 1998-06-08 2001-03-21 Advanced Medicine, Inc. Novel therapeutic agents that modulate 5-ht receptors
AU4550699A (en) * 1998-06-08 1999-12-30 Advanced Medicine, Inc. Multibinding agents that modulate the 5-ht transporter
AU765317C (en) * 1998-06-19 2004-05-20 H. Lundbeck A/S 4,5,6 and 7-indole and indoline derivatives, their preparation and use
IL139962A0 (en) * 1998-06-19 2002-02-10 Lundbeck & Co As H 4,5,6 and 7-indole and indoline derivatives, their preparation and use
AR020773A1 (es) 1998-10-16 2002-05-29 Duphar Int Res Compuesto derivados de 3-(tetrahidropiridin-4-il)indol, metodo para prepararlo, una composicion farmaceutica que los contiene, metodo para preparar dicha composicion y uso del compuesto
PT1140886E (pt) 1998-12-23 2003-08-29 Lundbeck & Co As H Metodo para a preparacao de 5- cianoftalida
ES2195554T5 (es) 1999-04-14 2010-02-02 H. Lundbeck A/S Metodo para la preparacion de citalopram.
WO2000069424A2 (en) * 1999-05-12 2000-11-23 Solvay Pharmaceuticals B.V. Method of treating psychotic disorders
US6355644B1 (en) 1999-06-14 2002-03-12 Neurogen Corporation Benzylpiperazinyl-indolinylethanones
AU5487300A (en) * 1999-06-14 2001-01-02 Neurogen Corporation Benzylpiperazinyl-indolinylethanones
US6642228B1 (en) * 1999-06-24 2003-11-04 Toray Industries, Inc. α1b-adrenergic receptor antagonists
SK287018B6 (sk) 1999-08-23 2009-09-07 Solvay Pharmaceuticals B. V. Deriváty fenylpiperazínov, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitie
JP2003517481A (ja) 1999-12-17 2003-05-27 ブリストルーマイヤーズ スクイブ カンパニー 抗精神病複素環式化合物
IL153234A0 (en) * 2000-06-14 2003-07-06 Lundbeck & Co As H Indole derivatives useful for the treatment of cns disorders
SI1294710T1 (en) * 2000-06-14 2005-10-31 H. Lundbeck A/S Indole derivatives useful for the treatment of cns disorders
AR028685A1 (es) 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol
EP1299380B1 (en) * 2000-06-29 2004-06-09 H. Lundbeck A/S Indole derivatives useful for the treatment of cns disorders
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
AR032712A1 (es) * 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
AR033287A1 (es) * 2001-05-09 2003-12-10 Lundbeck & Co As H Tratamiento del adhd
WO2003080050A1 (en) * 2002-03-27 2003-10-02 H. Lundbeck A/S The use of 3-[1-[2-(1-acetyl-2,3-dihydro-1h-indol-3-yl)ethyl]-3,6-dihydro-2h-pyridin-4-yl]-6-chloro-1h-indole or its enantiomers for the treatment of diseases and disorders responsive to 5-ht (serotonin) re-uptake inhibition
WO2003102097A1 (en) * 2002-05-31 2003-12-11 H. Lundbeck A/S The hydrochloride of (s)-(+)-3-[1-[2-(1-acetyl-2,3-dihydro-1h-indol-3-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-6-chloro-1h-indole
AU2003243930A1 (en) * 2002-07-05 2004-01-23 H. Lundbeck A/S Pharmaceutical composition comprising (s)-(+)-3-(1-(2-(1-acetyl-2,3-dihydro-1h-indol-3-yl)ethyl)-1,2,3,6-tetrahydropyridin-4-yl)-6-chloro-1h-indole
WO2004020437A1 (en) * 2002-08-29 2004-03-11 H. Lundbeck A/S S-(+)-3-{1-[2-(2,3-dihydro-1h-indol-3-yl)ethyl]-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof
WO2004080407A2 (en) * 2003-03-07 2004-09-23 Predix Pharmaceuticals Holdings, Inc. New serotonin modulating compounds and uses therefor
NZ551543A (en) * 2004-05-11 2009-12-24 Egis Gyogyszergyar Nyrt Pyridine derivatives of alkyl oxindoles as 5-HT7 receptor active agents
ATE537153T1 (de) * 2004-09-09 2011-12-15 Merck Sharp & Dohme Arylspirolactamverbindungen als antagonisten des cgrp-rezeptors
DE602005016836D1 (de) * 2004-11-26 2009-11-05 Janssen Pharmaceutica Nv Chotischer und anxiolytischer aktivität
TW200800960A (en) * 2005-08-17 2008-01-01 Lundbeck & Co As H Novel 2,3-dihydroindole compounds
US7544685B2 (en) 2005-08-17 2009-06-09 H. Lundbeck A/S 2,3-dihydroindole compounds
WO2007050381A2 (en) * 2005-10-24 2007-05-03 Janssen Pharmaceutica, N.V. 3-piperidin-4-yl-indole orl-1 receptor modulators
WO2008015516A1 (en) * 2006-07-28 2008-02-07 Pfizer Products Inc. Fused tricyclic heterocycles for the treatment of schizophrenia
WO2008066900A1 (en) * 2006-11-28 2008-06-05 Valeant Pharmaceuticals International 1,4 diamino bicyclic retigabine analogues as potassium channel modulators
PL395469A1 (pl) 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego
WO2014102589A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
WO2014102588A2 (en) * 2012-12-27 2014-07-03 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US20210380536A1 (en) * 2018-10-17 2021-12-09 Nikang Therapeutics, Inc. Indane derivatives as hypoxia inducible factor-2(alpha) inhibitors
GB201919213D0 (en) * 2019-12-23 2020-02-05 Ucb Biopharma Sprl Dihydrocyclopenta-Isoquinoline-Sulfanamide derivatives compounds

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EP0316723B1 (en) * 1987-11-20 1992-09-30 Hoechst-Roussel Pharmaceuticals Incorporated 3-[4(1-Substituted-4-piperazinyl)butyl]-4-thiazolidinones a process for their preparation and their use as medicaments
FR2654104B1 (fr) 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
IE68675B1 (en) 1990-11-01 1996-07-10 Takeda Chemical Industries Ltd Aminocoumaran derivatives their production and use
FR2670491B1 (fr) 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
GB9305641D0 (en) 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
AU6215594A (en) 1993-03-18 1994-10-11 Merck Sharp & Dohme Limited Indole derivatives as dopamine d4 antagonists
DE4414113A1 (de) 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
JPH09512542A (ja) 1994-04-28 1997-12-16 メルク シヤープ エンド ドーム リミテツド D▲下4▼リセプタ拮抗剤としてのベンゾフラン誘導体
IL114026A (en) * 1994-06-08 1999-06-20 Lundbeck & Co As H 4-aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzo thiophenemethyl) piperidines tetrahydropyridines or piperazines and pharmaceutical compositions containing them
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
AU765317C (en) * 1998-06-19 2004-05-20 H. Lundbeck A/S 4,5,6 and 7-indole and indoline derivatives, their preparation and use

Also Published As

Publication number Publication date
ES2185058T3 (es) 2003-04-16
EP0946542A1 (en) 1999-10-06
WO1998028293A1 (en) 1998-07-02
JP3251300B2 (ja) 2002-01-28
IS5061A (is) 1999-05-28
US20010021777A1 (en) 2001-09-13
CN1282644C (zh) 2006-11-01
PT946542E (pt) 2003-02-28
SK283678B6 (sk) 2003-11-04
NO318978B1 (no) 2005-05-30
KR20000069621A (ko) 2000-11-25
AR008545A1 (es) 2000-01-19
IL130133A0 (en) 2000-06-01
ZA9711376B (en) 1998-07-21
CN1146556C (zh) 2004-04-21
HUP0000079A3 (en) 2002-11-28
HUP0000079A2 (hu) 2001-10-28
DK0946542T3 (da) 2003-02-10
CZ222799A3 (cs) 1999-12-15
US6262087B1 (en) 2001-07-17
CN1246117A (zh) 2000-03-01
DE69716296T2 (de) 2003-09-11
SK81399A3 (en) 1999-12-10
US6552044B2 (en) 2003-04-22
CN1515551A (zh) 2004-07-28
PL188418B1 (pl) 2005-01-31
IL130133A (en) 2005-08-31
ATE225784T1 (de) 2002-10-15
EA199900581A1 (ru) 2000-04-24
CN1495165A (zh) 2004-05-12
NO20044514L (no) 1999-08-13
US6352988B2 (en) 2002-03-05
EP0946542B1 (en) 2002-10-09
CN1244558C (zh) 2006-03-08
NZ335973A (en) 2000-11-24
HK1025775A1 (en) 2000-11-24
CZ297416B6 (cs) 2006-12-13
BG103561A (en) 2000-06-30
BG63968B1 (bg) 2003-08-29
US20010020095A1 (en) 2001-09-06
TR199901407T2 (xx) 1999-08-23
IS2018B (is) 2005-06-15
AU5310998A (en) 1998-07-17
JP2000513731A (ja) 2000-10-17
KR100432297B1 (ko) 2004-05-20
PL334011A1 (en) 2000-01-31
NO992895L (no) 1999-08-13
BR9714039A (pt) 2000-05-09
EA002158B1 (ru) 2001-12-24
UA66778C2 (uk) 2004-06-15
DE69716296D1 (de) 2002-11-14
AU731243B2 (en) 2001-03-29

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