NO991132L - 3-Substituerte pyrido[4',3',:4,5]tieno[2,3-D]pyrimidin-derivater, fremstilling og anvendelse derav - Google Patents

3-Substituerte pyrido[4',3',:4,5]tieno[2,3-D]pyrimidin-derivater, fremstilling og anvendelse derav

Info

Publication number
NO991132L
NO991132L NO991132A NO991132A NO991132L NO 991132 L NO991132 L NO 991132L NO 991132 A NO991132 A NO 991132A NO 991132 A NO991132 A NO 991132A NO 991132 L NO991132 L NO 991132L
Authority
NO
Norway
Prior art keywords
substituted
alkyl
trifluoromethyl
hydroxyl
residue
Prior art date
Application number
NO991132A
Other languages
English (en)
Norwegian (no)
Other versions
NO991132D0 (no
Inventor
Gerd Steiner
Wilfried Lubisch
Alfred Bach
Franz Emling
Karsten Wicke
Hans-Juergen Teschendorf
Berthold Behl
Frank Kerrigan
Sharon Cheetham
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO991132D0 publication Critical patent/NO991132D0/no
Publication of NO991132L publication Critical patent/NO991132L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO991132A 1996-09-10 1999-03-09 3-Substituerte pyrido[4',3',:4,5]tieno[2,3-D]pyrimidin-derivater, fremstilling og anvendelse derav NO991132L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19636769A DE19636769A1 (de) 1996-09-10 1996-09-10 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
PCT/EP1997/004593 WO1998011110A1 (de) 1996-09-10 1997-08-22 3-substituierte pyrido [4',3':4,5] thieno [2,3-d]pyrimidin-derivate, ihre herstellung und verwendung

Publications (2)

Publication Number Publication Date
NO991132D0 NO991132D0 (no) 1999-03-09
NO991132L true NO991132L (no) 1999-03-09

Family

ID=7805168

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991132A NO991132L (no) 1996-09-10 1999-03-09 3-Substituerte pyrido[4',3',:4,5]tieno[2,3-D]pyrimidin-derivater, fremstilling og anvendelse derav

Country Status (32)

Country Link
US (1) US6222034B1 (xx)
EP (1) EP0927184B1 (xx)
JP (1) JP2001500138A (xx)
KR (1) KR20000035987A (xx)
CN (2) CN1230962A (xx)
AR (1) AR009572A1 (xx)
AT (1) ATE252587T1 (xx)
AU (1) AU736678B2 (xx)
BG (1) BG63602B1 (xx)
BR (1) BR9711724A (xx)
CA (1) CA2265509A1 (xx)
CO (1) CO4900071A1 (xx)
CZ (1) CZ288896B6 (xx)
DE (2) DE19636769A1 (xx)
DK (1) DK0927184T3 (xx)
ES (1) ES2210570T3 (xx)
HK (1) HK1043593A1 (xx)
HR (1) HRP970484A2 (xx)
HU (1) HUP9904107A3 (xx)
ID (1) ID18260A (xx)
IL (1) IL128142A0 (xx)
NO (1) NO991132L (xx)
NZ (1) NZ334350A (xx)
PL (1) PL332144A1 (xx)
PT (1) PT927184E (xx)
RU (1) RU2198888C2 (xx)
SK (1) SK283039B6 (xx)
TR (1) TR199900503T2 (xx)
TW (1) TW480264B (xx)
UA (1) UA54449C2 (xx)
WO (1) WO1998011110A1 (xx)
ZA (1) ZA978081B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19724980A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724979A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19734444A1 (de) 1997-08-08 1999-02-11 Basf Ag 3-Substituierte 3,4,5,7-Tetrahydro-pyrrolo(3',4':4,5) thieno (2,3-d) pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19900545A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
DE19900673A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
FR2791980B1 (fr) * 1999-04-09 2001-07-06 Sod Conseils Rech Applic Pyrido-thieno-diazepines, leur procede de preparation, et les compositions pharmaceutiques les contenant
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
ATE374750T1 (de) * 2000-07-18 2007-10-15 Dainippon Sumitomo Pharma Co Serotoninwiederaufnahme-inhibitoren
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
US7030240B2 (en) * 2003-03-31 2006-04-18 Predix Pharmaceuticals Holdings, Inc. Piperidinylamino-thieno[2,3-d] pyrimidine compounds
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
US8114894B2 (en) * 2008-12-03 2012-02-14 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
RU2559626C9 (ru) * 2010-04-14 2016-05-27 Байер Интеллектуэль Проперти Гмбх Способ получения дитиин-тетракарбоксимидов

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE272079C (xx) *
DE272086C (xx) *
DE272088C (xx) *
DE1937459A1 (de) * 1968-08-02 1970-02-05 Ciba Geigy Neue Pyrimidinderivate und Verfahren zu ihrer Herstellung
US3823151A (en) * 1968-08-02 1974-07-09 Ciba Geigy Corp 4,5,6,7-tetrahydrothieno(2,3-d)pyridines
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩
DE3752141T2 (de) * 1986-02-24 1998-03-26 Mitsui Petrochemical Ind Mittel zur behandlung von neuropathie
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents

Also Published As

Publication number Publication date
CN1332168A (zh) 2002-01-23
CZ75999A3 (cs) 1999-06-16
AR009572A1 (es) 2000-04-26
HRP970484A2 (en) 1998-10-31
SK283039B6 (sk) 2003-02-04
ID18260A (id) 1998-03-19
EP0927184B1 (de) 2003-10-22
CA2265509A1 (en) 1998-03-19
NO991132D0 (no) 1999-03-09
TR199900503T2 (xx) 1999-07-21
ATE252587T1 (de) 2003-11-15
CO4900071A1 (es) 2000-03-27
HUP9904107A2 (hu) 2000-05-28
TW480264B (en) 2002-03-21
CZ288896B6 (cs) 2001-09-12
IL128142A0 (en) 1999-11-30
HK1043593A1 (zh) 2002-09-20
UA54449C2 (uk) 2003-03-17
KR20000035987A (ko) 2000-06-26
AU736678B2 (en) 2001-08-02
DE19636769A1 (de) 1998-03-12
SK23099A3 (en) 1999-08-06
DK0927184T3 (da) 2004-03-01
BG103122A (en) 1999-09-30
PT927184E (pt) 2004-03-31
BR9711724A (pt) 1999-08-24
ZA978081B (en) 1999-03-09
RU2198888C2 (ru) 2003-02-20
PL332144A1 (en) 1999-08-30
CN1230962A (zh) 1999-10-06
US6222034B1 (en) 2001-04-24
WO1998011110A1 (de) 1998-03-19
DE59710902D1 (de) 2003-11-27
ES2210570T3 (es) 2004-07-01
HUP9904107A3 (en) 2001-10-29
BG63602B1 (bg) 2002-06-28
EP0927184A1 (de) 1999-07-07
NZ334350A (en) 2000-07-28
JP2001500138A (ja) 2001-01-09
AU4207197A (en) 1998-04-02

Similar Documents

Publication Publication Date Title
NO991132L (no) 3-Substituerte pyrido[4',3',:4,5]tieno[2,3-D]pyrimidin-derivater, fremstilling og anvendelse derav
MY146532A (en) Thiazole derivative
NZ513561A (en) Pyridopyranoazepine derivatives, preparation and therapeutic use
DK0944617T3 (da) Krystaller af benzimidazolderivater og deres fremstilling
BG104248A (en) Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides
ES8802517A1 (es) Un procedimiento para preparar fenoxialquil (substituido con heterocido)-isoxazoles y furanos.
RU99106781A (ru) 3-замещенные производные пиридо[4',3':4,5]тиено[2,3-альфа]пиримидина, их получение и применение
HUP0400326A2 (hu) Orexin receptor antagonistákként alkalmazható ciklikus N-(aril-karbonil)-amin-származékok és ezeket tartalmazó gyógyszerkészítmények
NO20044592L (no) Aryl keton pyrrolo-triazinforbindelser nyttige som kinase inhibitorer
BR0215202A (pt) Compostos antagonistas seletivos a2b de pirimidina, sua sìntese e uso
BG104112A (en) 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazine derivatives and pharmaceutical compositions containing them
NO20072053L (no) Nye bis-azaindolderivater, fremstilling og farmasoytisk anvendelse derav som kinaseinhibitorer
DE602004024093D1 (de) 2,4-dioxo-3-chinazolinylarylsulfonylharnstoffe
TR199800464T1 (xx) Serotonin antagonistleri olarak kinolein-2(1H)-on t�revleri
BG103900A (en) 3-SUBSTITUTED 3,4-DIHYDRO-THIENO[2,3-d]PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND APPLICATION
NO970293L (no) Substituerte camptothecinderivater og fremgangsmåte for deres fremstilling
IT1232252B (it) Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione
NO20071008L (no) Fremgangsmate for fremstilling av N-piperidino-1,5-difenylpyrazol-3-karboksamidderivater
GR3031693T3 (en) Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
FR2847899B1 (fr) Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
NZ221699A (en) Pyridazinone derivatives; pharmaceutical compositions and intermediates
HUP0101469A2 (hu) 5-[(2-Imidazolidinilidén)-amino]-benzimidazol-származékok, előállításuk és alkalmazásuk javított metabolikus stabilitású alfa-adrenoceptor agonistákként
MXPA04003278A (es) Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina.
ZA921261B (en) Sulfonylurea derivatives, their preparation and their use.
MY132993A (en) 3-substituted pyrido [3',4': 4,5] thieno [2,3-d] pyrimidine derivatives, their preparation and use

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application